Fujikawa Makoto 藤川誠

… Alternative Names

藤川誠フジカワマコト

FUJIKAWA Makoto 藤川誠

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Researcher Number	90573048
Other IDs	https://orcid.org/0000-0002-8100-3718
Affiliation (Current)	2024: 愛知医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2017 – 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2014 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 2012 – 2013: 東京理科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / Pathological medical chemistry / Metabolomics Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator エネルギー代謝 / 呼吸鎖 / アルツハイマー病 / ミトコンドリア / インスリン / ATP合成 / GSIS / ATP / インスリン分泌 / 糖尿病 / 生体エネルギー代謝 / 代謝学 / エネルギー代謝制御 … More Except Principal Investigator … More in cilico分子設計 / キナーゼ阻害剤 / チロシンキナーゼ / アポトーシス / アロステリック部位 / ペプチド / in silico分子設計 / チロシンキナーゼ阻害剤 / Met / 癌 / 医薬分子設計 Less

血球エネルギー代謝解析による認知症早期診断の開発研究Principal Investigator
- Principal Investigator
  
  藤川誠
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Tokyo Medical and Dental University
Functional analysis of MLCK during insulin secretion in islet beta cellsPrincipal Investigator
- Principal Investigator
  
  Fujikawa Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Creation of novel anticancer lead compounds targeting receptor-type tyrosine kinase Met molecule
- Principal Investigator
  
  TANUMA Sei-ichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Science
Identification of novel energy metabolism-related genes by MASC assayPrincipal Investigator
- Principal Investigator
  
  FUJIKAWA Makoto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tokyo Medical and Dental University
  Tokyo University of Science

All 2014 2013 2012

All Journal Article Presentation Book

[Book] 波紋疾走ほとばしる生命エネルギー2014
- Author(s)
  Makoto Fujikawa
- Total Pages
  1
- Publisher
  日本生物工学会
- Data Source
  KAKENHI-PROJECT-24790917
[Journal Article] Population of ATP synthase molecules in mitochondria is limited by available 6.8-kDa proteolipid protein (MLQ)2014
- Author(s)
  Fujikawa M, Ohsakaya S, Sugawara K and Yoshida M
- Journal Title
  
  Genes Cells
  
  Volume: 19 Issue: 2 Pages: 153-60
- DOI
  10.1111/gtc.12121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790917
[Journal Article] Screening of protein kinase inhibitors and knockdown experiments identified four kinases that affect mitochondrial ATP synthesis activity2013
- Author(s)
  Sugawara K, Fujikawa M and Yoshida M
- Journal Title
  
  FEBS Lett
  
  Volume: 587 Issue: 23 Pages: 3843-7
- DOI
  10.1016/j.febslet.2013.10.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790917
[Journal Article] Implication of bidirectional promoters containing duplicated GGAA motifs of mitochondrial function-associated genes2013
- Author(s)
  F. Uchiumi, M. Fujikawa, S. Miyazaki, S. Tanuma
- Journal Title
  
  AIMS Mol. Sci
  
  Volume: 1 Pages: 1-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460156
[Journal Article] Evaluation of intra-mitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation2013
- Author(s)
  Kioka H, Kato H, Fujikawa M, Tsukamoto O, Suzuki T, Imamura H, Nakano A, Higo S, Yamazaki S, Matsuzaki T, Tkafuji K, Asanuma H, Asakura M, Minamino T, Shintani Y, Yoshida M, Noji H, Kitakaze M, Komuro I, Asano Y and Takashima S
- Journal Title
  
  PNAS
  
  Volume: 111 Issue: 1 Pages: 273-278
- DOI
  10.1073/pnas.1318547111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-23227006, KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24570149, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790757, KAKENHI-PROJECT-24790917, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-25461119, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26461108
[Journal Article] Distribution and Dynamics of Intracellular ATP Level, and their Regulation2013
- Author(s)
  今村博臣、安東友美、藤川誠
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 53 Issue: 1 Pages: 020-023
- DOI
  10.2142/biophys.53.020
- NAID
  10031139021
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687011, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790917
[Journal Article] Effects of thujaplicins on the promoter activities of the human SIRT1 and telomere maintenance factor encoding genes2012
- Author(s)
  F. Uchiumi, H. Tachibana, H. Abe, A. Yoshimori , T. Kamiya, M. Fujikawa, S. Larsen, A. Honma, S. Ebizuka, S. Tanuma.
- Journal Title
  
  Pharmaceutica Analytica Acta
  
  Volume: 3 Issue: 05 Pages: 159-159
- DOI
  10.4172/2153-2435.1000159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590107, KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-24510270, KAKENHI-PROJECT-24790917
[Journal Article] Assessing the actual contribution of IF1, an inhibitor of mitochondrial FoF1, to ATP homeostasis, cell growth, mitochondrial morphology and cell viability2012
- Author(s)
  Fujikawa M, Imamura H, Nakamura J, Yoshida M
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Issue: 22 Pages: 18781-18787
- DOI
  10.1074/jbc.m112.345793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590977, KAKENHI-PROJECT-22687011, KAKENHI-PROJECT-23227006, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790917
[Presentation] ヒトGlyoxalase I SNPの活性に対する影響についてのin silico, in vitro解析2014
- Author(s)
  嶋田　奈実，藤川　誠，吉森　篤史，高澤　涼子，田沼　靖一
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本大学黒髪キャンパス，水道町周辺
- Data Source
  KAKENHI-PROJECT-25460156
[Presentation] in silico手法を用いた新規HMGB1/RAGE結合阻害剤の創製2014
- Author(s)
  手井　祐太，小川　夏実，横上　菜月，橘　晴輝，吉森　篤史，藤川　誠，高澤　涼子，田沼　靖一
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本大学黒髪キャンパス，水道町周辺
- Data Source
  KAKENHI-PROJECT-25460156
[Presentation] アポトーシスにおけるGSK-3β限定分解の分子機構の解明2013
- Author(s)
  西岡隼哉, 衛藤慎一, 藤川誠, 秋本和憲, 高澤涼子, 田沼靖一
- Organizer
  第86回日本生化学大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25460156
[Presentation] ヒトGlyoxalase I のSNPによる活性の差異に関する検討2013
- Author(s)
  嶋田奈実, 藤川誠, 高澤涼子, 田沼靖一
- Organizer
  第86回日本生化学大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25460156
[Presentation] マッシュルームチロシナーゼに対するツヤプリシン類の結合部位のホットスポットアミノ酸残基の構造学的解析2013
- Author(s)
  大山貴央, 高橋哲, 吉森篤史, 藤川誠, 阿部英明, 神谷貴紀, 海老塚重夫, 阿部武彦, 田沼靖一
- Organizer
  第86回日本生化学大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25460156
[Presentation] IF1 (mitochondrial FoF1 inhibitor protein); from single molecule to knock-out mouse2012
- Author(s)
  T. Suzuki, M. Fujikawa, J. Nakamura, M. Yoshida
- Organizer
  EBEC (European Bioenergetics Conference)
- Place of Presentation
  ドイツ (フライブルグ)
- Data Source
  KAKENHI-PROJECT-24790917
[Presentation] Functional identification of unknown genes localized at mitochondria using MASC assay2012
- Author(s)
  Fujikawa M, Mori M, Sugawara K and Yoshida M
- Organizer
  Japan Society of Cell Biology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790917
[Presentation] Screening of protein kinase inhibitors that affect ATP synthesis activity using MASC assay2012
- Author(s)
  K. Sugawara, M. Fujikawa, M. Yoshida
- Organizer
  EBEC (European Bioenergetics Conference)
- Place of Presentation
  ドイツ (フライブルグ)
- Data Source
  KAKENHI-PROJECT-24790917
[Presentation] A novel mitochondrial protein m62, which is identified by MASC assay screening, is essential for FoF1-ATP synthase activity and the mRNA level is regulated by the amount of glucose supply2012
- Author(s)
  Fujikawa M and Yoshida M
- Organizer
  Molecular Biology Society of Japan
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790917
[Presentation] Novel factors essential for human mitochondrial FoF1-ATP synthase activity found by MASC (Mitochondrial Activity of SLO-permeabilized Cells) screening2012
- Author(s)
  Fujikawa M and Yoshida M
- Organizer
  EBEC (European Bioenergetics Conference)
- Place of Presentation
  ドイツ (フライブルグ)
- Data Source
  KAKENHI-PROJECT-24790917

1. TANUMA Sei-ichi (10142449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. TAKASAWA Ryoko (10398828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. IMAMURA Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 野地博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujikawa Makoto 藤川 誠

藤川 誠 フジカワ マコト

FUJIKAWA Makoto 藤川 誠

Research Projects

Research Products

Co-Researchers

血球エネルギー代謝解析による認知症早期診断の開発研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of MLCK during insulin secretion in islet beta cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation of novel anticancer lead compounds targeting receptor-type tyrosine kinase Met molecule

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel energy metabolism-related genes by MASC assayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 波紋疾走 ほとばしる生命エネルギー2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Population of ATP synthase molecules in mitochondria is limited by available 6.8-kDa proteolipid protein (MLQ)2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Screening of protein kinase inhibitors and knockdown experiments identified four kinases that affect mitochondrial ATP synthesis activity2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Implication of bidirectional promoters containing duplicated GGAA motifs of mitochondrial function-associated genes2013

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of intra-mitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distribution and Dynamics of Intracellular ATP Level, and their Regulation2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Effects of thujaplicins on the promoter activities of the human SIRT1 and telomere maintenance factor encoding genes2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Assessing the actual contribution of IF1, an inhibitor of mitochondrial FoF1, to ATP homeostasis, cell growth, mitochondrial morphology and cell viability2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヒトGlyoxalase I SNPの活性に対する影響についてのin silico, in vitro解析2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] in silico手法を用いた新規HMGB1/RAGE結合阻害剤の創製2014

Author(s)

Organizer

Fujikawa Makoto 藤川誠

藤川誠フジカワマコト

FUJIKAWA Makoto 藤川誠

[Book] 波紋疾走ほとばしる生命エネルギー2014