Kawaguchi Kazunori 川口和紀

… Alternative Names

KAWAGUCHI Kazunori 川口和紀

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Researcher Number	90579632
Other IDs
Affiliation (Current)	2025: 金沢大学, 医学系, 協力研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 金沢大学, 医学系, 協力研究員 2021: 金沢大学, 医学系, 特任教授 2019: 金沢大学, 医学系, 特任教授 2016 – 2018: 金沢大学, 附属病院, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology
Keywords	Principal Investigator B型肝炎ウイルス / シングルセル解析 / 肝星細胞 / 肝類洞内皮細胞 / 肝非実質細胞 / 肝細胞増殖因子 / 類洞内皮細胞 / 血管内皮細胞 / ウィルス / 細胞分離 … More / 肝細胞がん / 肝線維化 / HBV cccDNA / Notchシグナル / 核酸アナログ / 肝細胞癌 … More Except Principal Investigator ウィルス / 発現制御 / 感染症 / 遺伝子 / ウイルス Less

Viral impact of hepatic non-parenchymal cells on Hepatitis B virus infected hepatocytesPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Kazunori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa University
Pathological deterioration of liver component cells by hepatitis B virus infection and the mechanism of hepatocarcinogenesisPrincipal Investigator
- Principal Investigator
  
  Kawaguchi Kazunori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
B型肝炎ウイルスゲノタイプ別感染肝組織構成細胞の変化と病態の解明Principal Investigator
- Principal Investigator
  
  川口和紀
- Project Period (FY)
  2017
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Elucidation of the mechanisms of HBV infection using single cell transcriptome analysis
- Principal Investigator
  
  HONDA Masao
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 肝臓クリニカルアップデート2018
- Author(s)
  川口和紀、本多政夫、金子周一
- Total Pages
  4
- Publisher
  医学図書出版
- ISBN
  9784865172928
- Data Source
  KAKENHI-PROJECT-17K09414
[Book] 内科学（第11版）【机上版】2017
- Author(s)
  矢﨑義雄（総編集）, 川口和紀
- Total Pages
  2534
- Publisher
  朝倉書店
- ISBN
  9784254322705
- Data Source
  KAKENHI-PROJECT-17K09414
[Journal Article] Serum MYCN as a predictive biomarker of prognosis and therapeutic response in the prevention of hepatocellular carcinoma recurrence2024
- Author(s)
  Qin XY, Shirakami Y, Honda M, Yeh SH, Numata K, Lai YY, Li CL, Wei F, Xu Y, Imai K, Takai K, Chuma M, Komatsu N, Furutani Y, Gailhouste L, Aikata H, Chayama K, Enomoto M, Tateishi R, Kawaguchi K, Yamashita T, Kaneko S, Nagaoka K, Tanaka M, Sasaki Y, Tanaka Y, Baba H, Miura K, Ochi S, Masaki T, et al
- Journal Title
  
  International Journal of Cancer
  
  Volume: － Issue: 3 Pages: 582-594
- DOI
  10.1002/ijc.34893
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08342, KAKENHI-PROJECT-21K07892, KAKENHI-PROJECT-22K08724, KAKENHI-PROJECT-20K07349, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K07940
[Journal Article] Potential utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction?associated steatohepatitis2024
- Author(s)
  Lyu Junyan、Okada Hikari、Sunagozaka Hajime、Kawaguchi Kazunori、Shimakami Tetsuro、Nio Kouki、Murai Kazuhisa、Shirasaki Takayoshi、Yoshida Mika、Arai Kuniaki、Yamashita Tatsuya、Tanaka Takuji、Harada Kenichi、Takamura Toshinari、Kaneko Shuichi、Yamashita Taro、Honda Masao
- Journal Title
  
  Hepatology Communications
  
  Volume: 8 Issue: 5
- DOI
  10.1097/hc9.0000000000000425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-21H04823
[Journal Article] Nucleos(t)ide analogs for hepatitis B virus infection differentially regulate the growth factor signaling in hepatocytes2024
- Author(s)
  Shimizu Ryogo、Murai Kazuhisa、Tanaka Kensuke、Sato Yuga、Takeda Naho、Nakasyo Saki、Shirasaki Takayoshi、Kawaguchi Kazunori、Shimakami Tetsuro、Nio Kouki、Nakaya Yuki、Kagiwada Harumi、Horimoto Katsuhisa、Mizokami Masashi、Kaneko Shuichi、Murata Kazumoto、Yamashita Taro、Honda Masao
- Journal Title
  
  Hepatology Communications
  
  Volume: 8 Issue: 1
- DOI
  10.1097/hc9.0000000000000351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-21H04823
[Journal Article] Aldo-keto reductase family 1 member B10 is regulated by nucleos(t)ide analogues for chronic hepatitis B2023
- Author(s)
  Orita Noriaki、Kawaguchi Kazunori、Honda Masao、Shimode Tetsuhiro、Hayakawa Nozomu、Terashima Takeshi、Komura Takuya、Nishikawa Masashi、Horii Rika、Nio Kouki、Shimakami Tetsuro、Takatori Hajime、Arai Kuniaki、Sakai Yoshio、Yamashita Tatsuya、Mizukoshi Eishiro、Kaneko Shuichi、Kagaya Takashi、Yamashita Taro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 674 Pages: 133-139
- DOI
  10.1016/j.bbrc.2023.06.093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16984, KAKENHI-PROJECT-21K07940
[Journal Article] Functional involvement of endothelial lipase in hepatitis B virus infection2023
- Author(s)
  Shirasaki Takayoshi、Murai Kazuhisa、Ishida Atsuya、Kuroki Kazuyuki、Kawaguchi Kazunori、Wang Ying、Ito Satoru、Matsushima Kouji、Yanagawa Hiroshi、Yamashita Taro、Kaneko Shuichi、Honda Masao
- Journal Title
  
  Hepatology Communications
  
  Volume: 7 Issue: 9
- DOI
  10.1097/hc9.0000000000000206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-21H04823
[Journal Article] Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation2023
- Author(s)
  Li Ying-Yi、Kuroki Kazuyuki、Shimakami Tetsuro、Murai Kazuhisa、Kawaguchi Kazunori、Yamashita Taro、Kaneko Shuichi、Honda Masao
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 15 Issue: 3 Pages: 533-558
- DOI
  10.1016/j.jcmgh.2022.10.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07940
[Journal Article] Identification of a Transmembrane Protein Involved in Shear Stress Signaling and Hepatocarcinogenesis After a Sustained Virological Response to Hepatitis C Virus2023
- Author(s)
  Nishikawa Masashi、Okada Hikari、Kawaguchi Kazunori、Shimakami Tetsuro、Nio Kouki、Arai Kuniaki、Yamashita Tatsuya、Sasaki Motoko、Kaneko Shuichi、Yamashita Taro、Honda Masao
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 16 Issue: 2 Pages: 263-286
- DOI
  10.1016/j.jcmgh.2023.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06957, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-21K07905, KAKENHI-PROJECT-21H04823
[Journal Article] Alterations in Hepatocellular Carcinoma-Specific Immune Responses Following Hepatitis C Virus Elimination by Direct-Acting Antivirals2022
- Author(s)
  Li Shihui、Mizukoshi Eishiro、Kawaguchi Kazunori、Miura Miyabi、Nishino Michiko、Shimakami Tetsuro、Arai Kuniaki、Yamashita Taro、Sakai Yoshio、Yamashita Tatsuya、Honda Masao、Kaneko Shuichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 19 Pages: 11623-11623
- DOI
  10.3390/ijms231911623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-21H02899
[Journal Article] A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes2022
- Author(s)
  Sumiyadorj Ariunaa、Murai Kazuhisa、Shimakami Tetsuro、Kuroki Kazuyuki、Nishikawa Tomoki、Kakuya Masaki、Yamada Atsumu、Wang Ying、Ishida Atsuya、Shirasaki Takayoshi、Kawase Shotaro、Li Ying‐Yi、Okada Hikari、Nio Kouki、Kawaguchi Kazunori、Honda Masao、Kaneko Shuichi
- Journal Title
  
  Hepatology Communications
  
  Volume: 6 Issue: 9 Pages: 2441-2454
- DOI
  10.1002/hep4.2018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20KK0178
[Journal Article] Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET2022
- Author(s)
  Shirasaki Takayoshi、Yamagoe Satoshi、Shimakami Tetsuro、Murai Kazuhisa、Imamura Ryu、Ishii Kiyo-Aki、Takayama Hiroaki、Matsumoto Yukako、Tajima-Shirasaki Natsumi、Yamashita Taro、Yoshikawa Tomoki、Takimoto Kazuhiro、Kaneko Shuichi、Matsumoto Kunio、Takamura Toshinari、Honda Masao
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 3176-3176
- DOI
  10.1038/s41467-022-30879-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-21H02695
[Journal Article] Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice2021
- Author(s)
  Ishida Kosuke、Seki Akihiro、Kawaguchi Kazunori、Nasti Alessandro、Yamato Masatoshi、Inui Hiiro、Komura Takuya、Yamashita Taro、Arai Kuniaki、Yamashita Tatsuya、Mizukoshi Eishiro、Honda Masao、Wada Takashi、Harada Kenichi、Kaneko Shuichi、Sakai Yoshio
- Journal Title
  
  Stem Cell Research
  
  Volume: 54 Pages: 102425-102425
- DOI
  10.1016/j.scr.2021.102425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-20K08327, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20K17017
[Journal Article] Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy2021
- Author(s)
  Sakai Y, Fukunishi S, Takamura M, Kawaguchi K, Inoue O, Usui S, Takashima S, Seki A, Asai A, Tsuchimoto Y, Nasti A, Bich Ho TT, Imai Y, Yoshimura K, Murayama T, Yamashita T, Arai K, Yamashita T, Mizukoshi E, Honda M, Wada T, Harada K, Higuchi K, Kaneko S.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 18 Pages: 97-101
- DOI
  10.1016/j.reth.2021.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-17H01886, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-21K07940
[Journal Article] Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair2021
- Author(s)
  Yano M, Honda M, Wada T, Kaneko S, Sakai Y.（ほか17名、19番目）
- Journal Title
  
  Regenerative Therapy
  
  Volume: 18 Pages: 497-507
- DOI
  10.1016/j.reth.2021.11.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-20K08327, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20K17017
[Journal Article] Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma2020
- Author(s)
  Hashiba Tomomi、Yamashita Taro、et al
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 20 Issue: 2 Pages: 30039-4
- DOI
  10.1016/j.jcmgh.2020.02.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02792, KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-18K19538, KAKENHI-PROJECT-17K15934, KAKENHI-PROJECT-20K08280, KAKENHI-PROJECT-19K17485
[Journal Article] DOCK11 and DENND2A play pivotal roles in the maintenance of hepatitis B virus in host cells.2020
- Author(s)
  Hashimoto S, Shirasaki T, Yamashita T, Iwabuchi S, Suzuki Y, Takamura Y, Ukita Y, Deshimaru S, Okayama T, Ikeo K, Kuroki K, Kawaguchi K, Mizukoshi E, Matsushima K, Honda M, Kaneko S
- Journal Title
  
  PLoS One
  
  Volume: 16(2) Issue: 2 Pages: e0246313-e0246313
- DOI
  10.1371/journal.pone.0246313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06399, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20H02592
[Journal Article] Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation2019
- Author(s)
  Wang Zijing、Kawaguchi Kazunori、Honda Masao、Hashimoto Shinichi、Shirasaki Takayoshi、Okada Hikari、Orita Noriaki、Shimakami Tetsuro、Yamashita Taro、Sakai Yoshio、Mizukoshi Eishiro、Murakami Seishi、Kaneko Shuichi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1621-1621
- DOI
  10.1038/s41598-018-38139-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17H01540
[Journal Article] Surrogacy of Time to Progression for Overall Survival in Advanced Hepatocellular Carcinoma Treated with Systemic Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials2019
- Author(s)
  Terashima Takeshi、Yamashita Tatsuya、Toyama Tadashi、Arai Kuniaki、Kawaguchi Kazunori、Kitamura Kazuya、Yamashita Taro、Sakai Yoshio、Mizukoshi Eishiro、Honda Masao、Kaneko Shuichi
- Journal Title
  
  Liver Cancer
  
  Volume: 8 Issue: 2 Pages: 130-139
- DOI
  10.1159/000489505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17K09413
[Journal Article] B型肝炎ウイルス感染状態における肝の細胞間シグナル機構2019
- Author(s)
  川口和紀、本多政夫、金子周一
- Journal Title
  
  月刊「細胞」
  
  Volume: 51 Pages: 29-31
- Data Source
  KAKENHI-PROJECT-17K09414
[Journal Article] Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis.2019
- Author(s)
  M Kanno, K Kawaguchi, M Honda, R Horii, H Takatori, T Shimakami, K Kitamura, K Arai, T Yamashita, Y Sakai, T Yamashita, E Mizukoshi, S Kaneko.
- Journal Title
  
  J Gastroenterol
  
  Volume: - Issue: 6 Pages: 549-557
- DOI
  10.1007/s00535-019-01551-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-18H02793, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414
[Journal Article] Distinct notch signaling expression patterns between nucleoside and nucleotide analogues treatment for hepatitis B virus infection.2018
- Author(s)
  Wang Z, Kawaguchi K, Honda M, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 501 Issue: 3 Pages: 682-687
- DOI
  10.1016/j.bbrc.2018.04.236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-18H02793
[Journal Article] Analysis of the liver functional reserve of patients with advanced hepatocellular carcinoma undergoing sorafenib treatment: Prospects for regorafenib therapy.2018
- Author(s)
  Terashima T, Yamashita T, Sunagozaka H, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.
- Journal Title
  
  Hepatol Res
  
  Volume: 48 Issue: 12 Pages: 956-966
- DOI
  10.1111/hepr.13196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-17K15934, KAKENHI-PROJECT-18H02793
[Journal Article] The Role of Notch Signaling in Liver Diseases: Contribution to Development and Cancer2017
- Author(s)
  Kawaguchi Kazunori、Honda Masao、Kaneko Shuichi
- Journal Title
  
  International Journal of Cancer and Clinical Research
  
  Volume: 4 Issue: 1
- DOI
  10.23937/2378-3419/1410079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09414
[Journal Article] Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B.2017
- Author(s)
  Kawaguchi K, Honda M, Ohta H, Terashima T, Shimakami T, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Komura T, Unoura M, Kaneko S
- Journal Title
  
  J Gastroenterol
  
  Volume: ePub ahead Issue: 6 Pages: 740-751
- DOI
  10.1007/s00535-017-1386-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-17K15934, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-18H02793
[Journal Article] Beneficial Effect of Maintaining Hepatic Reserve during Chemotherapy on the Outcomes of Patients with Hepatocellular Carcinoma.2017
- Author(s)
  Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.
- Journal Title
  
  Liver Cancer
  
  Volume: 6 Issue: 3 Pages: 236-249
- DOI
  10.1159/000472262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-17K15934, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H04695
[Journal Article] Phase I clinical study of liver regenerative therapy for cirrhosis by intrahepatic arterial infusion of freshly isolated autologous adipose tissue-derived stromal/stem (regenerative) cell.2017
- Author(s)
  Sakai Y, Takamura M, Seki A, Sunagozaka H, Terashima T, Komura T, Yamato M, Miyazawa M,　Kawaguchi K, Nasti A, Mochida H, Usui S, Otani N, Ochiya T, Wada T, Honda M, Kaneko S
- Journal Title
  
  Regenerative Therapy
  
  Volume: 6 Pages: 52-64
- DOI
  10.1016/j.reth.2016.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414
[Journal Article] HBcrAg predicts hepatocellular carcinoma development: An analysis using time-dependent receiver operating characteristics.2016
- Author(s)
  Kawaguchi K, Honda M, Kaneko S.
- Journal Title
  
  Transl Cancer Res.
  
  Volume: 5(S2) Issue: S2 Pages: S216-S220
- DOI
  10.21037/tcr.2016.08.13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16K15426
[Journal Article] Jagged1 DNA Copy Number Variation Is Associated with Poor Outcome in Liver Cancer.2016
- Author(s)
  Kawaguchi K, Honda M, Yamashita T, Okada H, Shirasaki T, Nishikawa M, Nio K, Arai K, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.
- Journal Title
  
  Am J Pathol.
  
  Volume: 186(8) Issue: 8 Pages: 2055-2067
- DOI
  10.1016/j.ajpath.2016.04.011
- NAID
  120005899105
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26460995, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K21058
[Journal Article] Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma.2016
- Author(s)
  Honda M, Shirasaki T, Terashima T, Kawaguchi K, Nakamura M, Oishi N, Wang X, Shimakami T, Okada H, Arai K, Yamashita T, Sakai Y, Yamashita T, Mizukoshi E, Kaneko S.
- Journal Title
  
  J Infect Dis
  
  Volume: 213 Issue: 7 Pages: 1096-1106
- DOI
  10.1093/infdis/jiv572
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460995, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H06827, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K21058
[Journal Article] Potential efficacy of therapies targeting intrahepatic lesions after sorafenib treatment of patients with hepatocellular carcinoma.2016
- Author(s)
  Yamashita T, Horii R, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.
- Journal Title
  
  BMC Cancer.
  
  Volume: 16(1) Issue: 1 Pages: 338-338
- DOI
  10.1186/s12885-016-2380-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H06827, KAKENHI-PROJECT-16K15426
[Journal Article] Response to chemotherapy improved hepatic reserve for patients with hepatocellular carcinoma and Child-Pugh B cirrhosis.2016
- Author(s)
  Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107(9) Issue: 9 Pages: 1263-1269
- DOI
  10.1111/cas.12992
- NAID
  120005851362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H06827, KAKENHI-PROJECT-26460995, KAKENHI-PROJECT-16K15426
[Presentation] 肝類洞内皮細胞がもたらすB型肝炎ウイルス動態の影響と亜鉛フィンガー抗ウイルス蛋白の役割2024
- Author(s)
  下出哲弘，野口綾，川口和紀，丹尾幸樹，島上哲朗，村居和寿，李影奕，黒木和夫，本多政夫，山下太郎
- Organizer
  第27回日本亜鉛栄養治療研究会学術集会
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] 肝組織内の内皮細胞がもたらす肝細胞内のB型肝炎ウイルス複製の影響2023
- Author(s)
  下出哲弘，川口和紀，山下太郎
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] HGFを介した内皮細胞によるHBV感染肝細胞のウイルス複製への影響2023
- Author(s)
  下出哲弘，川口和紀，本多政夫，岡田光，関晃裕，丹尾幸樹，島上哲朗，酒井佳夫，水腰英四郎，金子周一，山下太郎
- Organizer
  第30回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] 肝類洞内皮細胞によるHBV感染肝細胞のAkt-mTOR経路を介したウイルス複製への影響2022
- Author(s)
  下出哲弘、川口和紀、本多政夫、岡田光、村居和寿、李影奕、丹尾幸樹、島上哲朗、荒井邦明、酒井佳夫、山下竜也、水腰英四郎、金子周一、黒木和之、山下太郎
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] 肝非実質細胞がもたらすB型肝炎ウイルス感染肝細胞におけるシグナル伝達因子の変化2022
- Author(s)
  川口和紀、下出哲弘、金子周一
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] 脂肪組織由来間葉系幹細胞治療の非アルコール性脂肪肝炎肝細胞におけるNotchシグナルを介した修復機構2022
- Author(s)
  下出哲弘、石田晃介、関晃裕、川口和紀、Alessandro Nasti、金子周一、酒井佳夫
- Organizer
  第27回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] Liver sinusoidal endothelial cells affect hepatitis B virus replication in virus-infected hepatocytes via Akt-mTOR pathway2022
- Author(s)
  Tetsuhiro Shimode, Kazunori Kawaguchi, Noriaki Orita, Kouki Nio, Hikari Okada, Kazuhisa Murai, Kouki Nio, Kuniaki Arai, Taro Yamashita, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda
- Organizer
  The Liver Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] Dedicator of cytokinesis 11 is associated with the S/G2 cell cycle phase in hepatocytes with persistent hepatitis B virus infection2022
- Author(s)
  Kazunori Kawaguchi, Taro Yamashita, Kouki Nio, Tetsuro Shimakami, Yoshio Sakai, Eishiro Mizukoshi, Masao Honda
- Organizer
  The Liver Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] Endothelial cells affect HBV replication in hepatocytes in a non-contact manner2021
- Author(s)
  Tetsuhiro Shimode, Kazunori Kawaguchi, Masao Honda, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Shuichi Kaneko
- Organizer
  The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07940
[Presentation] Serum aldo-keto reductase family 1 member B10 predicts HBV-related hepatocellular carcinoma during nucleos(t)ide analogue treatment2019
- Author(s)
  Kazunori Kawaguchi, Masao Honda, Noriaki Orita, Masataka Kanno, Rika Horii, Kouki Nio, Takeshi Terashima, Tetsuro Shimakami, Kuniaki Arai, Taro Yamashita, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Shuichi Kaneko
- Organizer
  The Liver Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] Heterogeneity of tumor microenvironment in 2 different HBV-associated HCC2019
- Author(s)
  Sadahiro Iwabuchi, Kazunori Kawaguchi, Masao Honda, Taro Yamashita, Tatsuya Yamashita, Shuichi Kaneko, Shinichi Hashimoto
- Organizer
  2019 International HBV Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] 血清AKR1B10測定による核酸アナログ投与下HBV関連肝発癌予測2019
- Author(s)
  織田典明、川口和紀、金子周一
- Organizer
  第23回日本肝臓学会大会(JDDW)
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] mTORC2-related protein kinase B phosphorylation is associated with nucleotide analogues treatment for chronic hepatitis B2019
- Author(s)
  Kazunori Kawaguchi, Masao Honda, Zijing Wang, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Shuichi Kaneko
- Organizer
  APASL Single Topic Conference 2019 in Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] HBV cccDNAに作用する転写因子を標的とした抗HBV効果2018
- Author(s)
  川口和紀、本多政夫、金子周一
- Organizer
  日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] Notch signaling facilitates hepatitis B virus covalently closed circular DNA via cAMP response element-binding protein with ITCH modulation2018
- Author(s)
  Kazunori Kawaguchi, Zijing Wang, Masao Honda, Hikari Okada, Takayoshi Shirasaki, Shinichi Hashimoto, Seishi Murakami and Shuichi Kaneko
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] mTORC2-Akt phosphorylation is associated with Notch signaling activation by nucleotide analogues but not nucleoside analogues for chronic HBV infection2018
- Author(s)
  Kazunori Kawaguchi, Zijing Wang, Masao Honda, Takayoshi Shirasaki, Hikari Okada, Ying-Yi Li, Kazuhisa Murai, Kouki Nio, Tetsuro Shimakami, Taro Yamashita, Kazuyuki Kuroki, Shinichi Hashimoto, Seishi Murakami, Shuichi Kaneko
- Organizer
  2018 HBV meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] mTORC2-related protein kinase B phosphorylation is associated with Notch signaling activation by nucleotide analogues for chronic hepatitis B virus infection2018
- Author(s)
  Kazunori Kawaguchi, Zijing Wang, Masao Honda, Hikari Okada, Takayoshi Shirasaki, Kouki Nio, Tetsuro Shimakami, Kuniaki Arai, Taro Yamashita, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Shuichi Kaneko
- Organizer
  2018 AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] HBV生活環におけるNotchシグナルを介した核酸アナログの作用点に関する検討2018
- Author(s)
  川口和紀、本多政夫、金子周一
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] B型慢性肝炎患者の核酸アナログ投与下における肝線維化と肝発癌および再発予測2018
- Author(s)
  川口和紀、本多政夫、金子周一
- Organizer
  2018 JDDW
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] Notchシグナルのユビキチン・プロテアソーム系を介したB型肝炎ウイルスへの影響2018
- Author(s)
  王紫静、川口和紀、本多政夫、金子周一
- Organizer
  第23回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-17K09414
[Presentation] Nucleos(t)ide analogues and interferon affect intranuclear HBV genome in vitro via Notch signaling modification, independent of the ubiquitin-proteasome system2017
- Author(s)
  Kawaguchi Kazunori, Wang Zijing, Honda Masao, Shirasaki Takayoshi, Okada Hikari, Shimakami Tetsuro, Nio Kouki, Arai Kuniaki, Yamashita Taro, Sakai Yoshio, Yamashita Tatsuya, Mizukoshi Eishiro, Kaneko Shuichi
- Organizer
  The Liver Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09414

1. HONDA Masao (00272980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. SHIRASAKI Takayoshi (50547180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 橋本真一 (00313099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Oishi Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. YAMASHITA Taro

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. ISHII Kiyoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 酒井佳夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
9. 池尾一穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 寺島健志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 水腰英四郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 金子周一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 佐々木素子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawaguchi Kazunori 川口 和紀

KAWAGUCHI Kazunori 川口 和紀

Research Projects

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Co-Researchers

Viral impact of hepatic non-parenchymal cells on Hepatitis B virus infected hepatocytesPrincipal Investigator

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Pathological deterioration of liver component cells by hepatitis B virus infection and the mechanism of hepatocarcinogenesisPrincipal Investigator

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B型肝炎ウイルスゲノタイプ別感染肝組織構成細胞の変化と病態の解明Principal Investigator

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Elucidation of the mechanisms of HBV infection using single cell transcriptome analysis

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[Book] 肝臓クリニカルアップデート2018

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[Book] 内科学（第11版） 【机上版】2017

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[Journal Article] Serum MYCN as a predictive biomarker of prognosis and therapeutic response in the prevention of hepatocellular carcinoma recurrence2024

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[Journal Article] Potential utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction?associated steatohepatitis2024

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[Journal Article] Nucleos(t)ide analogs for hepatitis B virus infection differentially regulate the growth factor signaling in hepatocytes2024

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[Journal Article] Aldo-keto reductase family 1 member B10 is regulated by nucleos(t)ide analogues for chronic hepatitis B2023

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[Journal Article] Functional involvement of endothelial lipase in hepatitis B virus infection2023

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[Journal Article] Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation2023

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[Journal Article] Identification of a Transmembrane Protein Involved in Shear Stress Signaling and Hepatocarcinogenesis After a Sustained Virological Response to Hepatitis C Virus2023

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[Journal Article] Alterations in Hepatocellular Carcinoma-Specific Immune Responses Following Hepatitis C Virus Elimination by Direct-Acting Antivirals2022

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Kawaguchi Kazunori 川口和紀

KAWAGUCHI Kazunori 川口和紀

[Book] 内科学（第11版）【机上版】2017