kimura toru 木村亨

… Alternative Names

Kimura Toru 木村亨

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Researcher Number	90580796
Other IDs	https://orcid.org/0000-0003-4504-232X
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 大阪大学, 大学院医学系研究科, 助教 2021: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 呼吸器外科特別研究員 2020: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 呼吸器外科副部長 2019: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 呼吸器外科医長 2016: 大阪大学, 医学(系)研究科(研究院), 助教 2015: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員 2014: 独立行政法人国立循環器病研究センター, 研究所, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 55040:Respiratory surgery-related / Respiratory surgery Except Principal Investigator Basic Section 55040:Respiratory surgery-related
Keywords	Principal Investigator 肺癌 / 肺線維症 / 間質性肺炎 / 癌関連線維芽細胞 / 肺外科 / 線維芽細胞 / 間質性肺炎・肺線維症 / 間質性肺炎合併肺癌 / CNP / 間質性肺疾患 / ナトリウム利尿ペプチド / 急性増悪 … More Except Principal Investigator … More 肺移植 / 虚血再灌流障害 / キメラ抗原受容体T細胞療法 / 心停止 / 細胞死 / 肺胞マクロファージ / 移植免疫 / 腫瘍間質 / 胸腺上皮性腫瘍 / 肺胞上皮細胞 / 脂肪組織由来幹細胞 / 細胞移植治療 / 肺再生 / 慢性閉塞性肺疾患 / 脂肪幹細胞 / 免疫抑制 / 補体反応 / 拒絶反応 / 胸膜播種 / 肺癌 / 腫瘍微小環境 / 癌関連線維芽細胞 Less

早期肺癌組織内の線維芽細胞による細胞外基質改変の機序解明と悪性度診断法の探索Principal Investigator
- Principal Investigator
  
  木村亨
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Osaka
胸膜播種モデルマウスに対するFAP CAR-T細胞を用いた新規治療法の検討
- Principal Investigator
  
  杉浦裕典
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
肺移植後慢性拒絶反応における補体反応の機能解明と新規免疫学的治療の開発
- Principal Investigator
  
  池晃弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
Development of new lung regeneration therapies by elucidating the lung regeneration mechanism of adipose tissue-derived stem cells
- Principal Investigator
  
  福井絵里子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
胸腺上皮性腫瘍の腫瘍間質をターゲットとした治療戦略の探索
- Principal Investigator
  
  寛島隆史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
The role of alveolar macrophages and regulatory pathways in post-transplant lung inflammation.
- Principal Investigator
  
  櫻井禎子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
本邦での心停止ドナー肺移植開始を目指したネクロプトーシス制御による臓器保護戦略
- Principal Investigator
  
  狩野孝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
肺癌の間質形成と肺線維化における線維芽細胞を標的とした新規免疫療法の基盤確立Principal Investigator
- Principal Investigator
  
  木村亨
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka University
New Therapeutic Strategy for Lung Cancer with Interstitial Lung DiseasesPrincipal Investigator
- Principal Investigator
  
  Kimura Toru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Osaka International Cancer Institute
間質性肺疾患における肺癌の増殖・転移の機序解明とCNPによる新たな治療戦略の探索Principal Investigator
- Principal Investigator
  
  木村亨
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Osaka University
The development of a new therapy against interstitial lung disease using CNPPrincipal Investigator
- Principal Investigator
  
  Kimura Toru
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  National Cardiovascular Center Research Institute

All 2024 2022 2021 2020 2019 2016 2015 Other

All Journal Article Presentation

[Journal Article] Progressive changes in the protein expression profile of alveolar septa in early-stage lung adenocarcinoma2024
- Author(s)
  Kimura Toru、Akazawa Takashi、Mizote Yu、Nakamura Harumi、Sakaue Miki、Maniwa Tomohiro、Shintani Yasushi、Honma Keiichiro、Tahara Hideaki、Okami Jiro
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: - Issue: 6 Pages: 771-779
- DOI
  10.1007/s10147-024-02507-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09014
[Journal Article] A Novel Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-Kappa B Activation Pathway is Involved in the Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemia-Reperfusion Lung Injury2024
- Author(s)
  Miyashita Yudai、Kanou Takashi、Fukui Eriko、Matsui Takahiro、Kimura Toru、Ose Naoko、Funaki Soichiro、Shintani Yasushi
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 56 Issue: 2 Pages: 369-379
- DOI
  10.1016/j.transproceed.2024.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08293
[Journal Article] C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice.2016
- Author(s)
  Kimura T, Nojiri T, Hino J, Hosoda H, Miura K, Shintani Y, Inoue M, Zenitani M, Takabatake H, Miyazato M, Okumura M, Kangawa K.
- Journal Title
  
  Respiratory research
  
  Volume: 17 Issue: 1 Pages: 19-19
- DOI
  10.1186/s12931-016-0335-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-25461401, KAKENHI-PROJECT-26861135, KAKENHI-PROJECT-26293316
[Journal Article] Exacerbation of bleomycin-induced injury by lipopolysaccharide in mice: establishment of a mouse model for acute exacerbation of interstitial lung diseases.2015
- Author(s)
  Kimura T, Nojiri T, Hosoda H, Shintani Y, Inoue M, Miyazato M, Okumura M, Kangawa K.
- Journal Title
  
  European journal of cardio-thoracic surgery
  
  Volume: 48 Issue: 4 Pages: e85-e91
- DOI
  10.1093/ejcts/ezv261
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-26861135, KAKENHI-PROJECT-26293316
[Journal Article] Protective effects of C-type natriuretic peptide on cisplatin-induced nephrotoxicity in mice2015
- Author(s)
  Kimura, T., Nojiri, T., Hosoda, H., Ishikane, S., Shintani, Y., Inoue, M., Miyazato, M., Okumura, M., Kangawa, K.
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 75(5) Issue: 5 Pages: 1057-1063
- DOI
  10.1007/s00280-015-2734-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861319, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-26861135, KAKENHI-PROJECT-26293316
[Journal Article] C-type natriuretic peptide attenuates lipopolysaccharide-induced acute lung injury in mice2015
- Author(s)
  Kimura T, Nojiri T, Hosoda H, Ishikane S, Shintani Y, Inoue M, Miyazato M, Okumura M, Kangawa K
- Journal Title
  
  J Surg Res
  
  Volume: 194 Issue: 2 Pages: 631-637
- DOI
  10.1016/j.jss.2014.11.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22126002, KAKENHI-PROJECT-26293316, KAKENHI-PROJECT-26861135
[Presentation] 肺癌胸膜播種病変におけるFibroblast activation protein発現に関する検討2022
- Author(s)
  木村亨, 田中諒, 大村彰勲, 川岸紗千, 坂田龍平, 渡洋和, 馬庭知弘, 岡見次郎
- Organizer
  第39回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] 小型肺腺癌に対する縮小手術後の再発例に関する臨床病理学的検討2021
- Author(s)
  木村亨, 大村彰勲, 田中諒, 寛島隆史, 馬庭知弘, 中村ハルミ, 岡見次郎
- Organizer
  第38回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] 早期肺腺癌病変における間質形成とFibroblast Activation Protein発現に関する検討 (The Expression of Fibroblast Activation Protein in Stroma of Early-stage Lung Adenocarcinoma)2021
- Author(s)
  木村亨, 田中諒, 大村彰勲, 川岸紗千, 渡洋和, 馬庭知弘, 岡見次郎.
- Organizer
  第74回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] 間質性肺炎合併肺癌切除例における背景肺の病理学的評価と術後遠隔期の経過に関する検討2021
- Author(s)
  木村亨, 阪上未紀, 中村ハルミ, 渡洋和, 大村彰勲, 川岸紗千, 坂田龍平, 馬庭知弘, 本間圭一郎, 岡見次郎
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] 術式選択から見た間質性肺炎合併肺癌に対する肺切除術後予後の後方視的検討2020
- Author(s)
  木村亨、大村彰勲、池晃弘、寛島隆史、馬庭知弘、岡見次郎、東山聖彦
- Organizer
  日本呼吸器外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] 間質性肺炎合併肺癌の術後経過において肺癌と間質性肺炎が予後の与える影響についての検討2019
- Author(s)
  木村亨、大村彰勲、寛島隆史、池晃弘、馬庭知弘、岡見次郎、東山聖彦
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] 間質性肺炎合併肺癌における腫瘍の病理学的因子と背景肺との関連についての検討2019
- Author(s)
  木村亨、池晃弘、石田裕人、馬庭知弘、岡見次郎、東山聖彦
- Organizer
  第36回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] 肺線維症モデルマウスにおけるFibroblast Activation Proteinと肺線維化に関する検討2019
- Author(s)
  木村亨、大村彰勲、池晃弘、寛島隆史、馬庭知弘、岡見次郎、東山聖彦、Ellen Pure’、Steven M Albelda
- Organizer
  第72回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09314
[Presentation] Bleomycin誘発線維症肺における肺癌同所移植マウスモデルの検討2016
- Author(s)
  木村亨、野尻崇、細田洋司、新谷康、川村知裕、舟木壮一郎、別所俊哉、南正人、寒川賢治、奥村明之進
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪（大阪市）
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-16K19979
[Presentation] 間質性肺炎急性増悪モデルマウスの作製と新規治療法の探索2015
- Author(s)
  木村亨, 野尻崇, 細田洋司, 日野純, 新谷康, 川村知裕, 舟木壮一郎, 別所俊哉, 井上匡美, 南正人, 寒川賢治, 奥村明之進
- Organizer
  関西胸部外科学会
- Place of Presentation
  岡山
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] C-type natriuretic peptide atteuates bleomycin-induced fibrosis and inflammation in murine lung2015
- Author(s)
  Toru Kimura, Takashi Nojiri, Hihoshi Hosoda, Yasushi Shintani, Masayoshi Inoue, Mikiya Miyazato, Meinoshin Okumura, Kenji Kangawa
- Organizer
  16th World Conference on Lung Cancer
- Place of Presentation
  Denver, USA
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] 肺線維症に対するC型ナトリウム利尿ペプチドの効果2015
- Author(s)
  木村亨, 野尻崇, 細田洋司, 三浦浩一, 新谷康, 川村知裕, 舟木壮一郎, 井上匡美, 南正人, 寒川賢治, 奥村明之進
- Organizer
  日本呼吸器外科学会
- Place of Presentation
  香川
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] C-type natriuretic peptide atteuates acute and chronic inflammatory reactions in murine lung2015
- Author(s)
  Toru Kimura
- Organizer
  Thoracic Surgery Seminar in Kyoto
- Place of Presentation
  京都
- Year and Date
  2015-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] CNP attenuates renal toxicity induced by cisplatin in murine kidney2015
- Author(s)
  Toru Kimura, Takashi Nojiri, Hihoshi Hosoda, Mikiya Miyazato, Kenji Kangawa
- Organizer
  7th International Conference on cGMP
- Place of Presentation
  Trier, Germany
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] Establishment of a new mouse model for postoperative acute exacerbation in interstitial lung diseases2015
- Author(s)
  Toru Kimura, Takashi Nojiri, Hihoshi Hosoda, Yasushi Shintani, Masayoshi Inoue, Mikiya Miyazato, Meinoshin Okumura, Kenji Kangawa
- Organizer
  23rd European Conference on General Thoracic Surgery
- Place of Presentation
  Lisbon-Portugal
- Year and Date
  2015-05-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] C型ナトリウム利尿ペプチドによるヒト肺線維芽細胞の活性化抑制効果2015
- Author(s)
  木村亨, 野尻崇, 細田洋司, 三浦浩一, 新谷康, 川村知裕, 舟木壮一郎, 別所俊哉, 井上匡美, 南正人, 寒川賢治, 奥村明之進
- Organizer
  日本肺癌学会
- Place of Presentation
  横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] Protective effect of C-type natriuretic peptide on lipopolysaccharide-induced acute lung injury in mice
- Author(s)
  Toru Kimura, Takashi Nojiri, Hihoshi Hosoda, Yasushi Shintani, Shin Ishikane, Masayoshi Inoue, Mikiya Miyazato, Meinoshin Okumura, Kenji Kangawa
- Organizer
  22th European Conference on General Thoracic Surgery
- Place of Presentation
  Copenhagen
- Year and Date
  2014-06-15 – 2014-06-18
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] シスプラチン誘発急性腎障害モデルマウスに対するC型ナトリウム利尿ペプチドの腎保護効果についての検討
- Author(s)
  木村亨, 野尻崇, 細田洋司, 新谷康, 川村知裕, 舟木壮一郎, 井上匡美, 南正人, 寒川賢治, 奥村明之進
- Organizer
  第55回日本肺癌学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-11-14 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] Lipopolysaccaride誘発急性肺障害モデルマウスに対するC型ナトリウム利尿ペプチドの効果
- Author(s)
  木村亨, 野尻崇, 細田洋司, 新谷康, 川村知裕, 舟木壮一郎, 中桐伴行, 井上匡美, 澤端章好, 南正人, 寒川賢治, 奥村明之進
- Organizer
  第31回日本呼吸器外科学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] Protective effect of C-type natriuretic peptide on lipopolysaccharide-induced acute lung injury in mice
- Author(s)
  Toru Kimura, Takashi Nojiri, Hihoshi Hosoda, Yasushi Shintani, Shin Ishikane, Masayoshi Inoue, Mikiya Miyazato, Meinoshin Okumura, Kenji Kangawa
- Organizer
  The Conference on Bioactive Peptides for Cell-Cell Communication 2014
- Place of Presentation
  京都
- Year and Date
  2014-09-10 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-26861135
[Presentation] Bleomycin誘発肺障害マウスへのLipopolysaccharide吸入による間質性肺炎・肺線維症急性増悪モデルの作製
- Author(s)
  木村亨, 野尻崇, 細田洋司, 新谷康, 川村知裕, 舟木壮一郎, 中桐伴行, 井上匡美, 南正人, 寒川賢治, 奥村明之進
- Organizer
  第67回日本胸部外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2014-09-30 – 2014-10-02
- Data Source
  KAKENHI-PROJECT-26861135

1. 舟木壮一郎 (50464251)

# of Collaborated Projects: 8 results

# of Collaborated Products: 1 results
2. 新谷康 (90572983)

# of Collaborated Projects: 8 results

# of Collaborated Products: 2 results
3. 福井絵里子 (90814591)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. 狩野孝 (70528455)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
5. 大瀬尚子 (10570559)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
6. 保仙直毅 (10456923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 杉浦裕典 (30982029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 池晃弘 (50982021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 前田晃 (00319708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 寛島隆史 (90966673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 渡部直史 (90648932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 櫻井禎子 (80760496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 寒川賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. 細田洋司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 石兼真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 宮里幹也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kimura toru 木村 亨

Kimura Toru 木村 亨

Research Projects

Research Products

Co-Researchers

早期肺癌組織内の線維芽細胞による細胞外基質改変の機序解明と悪性度診断法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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胸膜播種モデルマウスに対するFAP CAR-T細胞を用いた新規治療法の検討

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肺移植後慢性拒絶反応における補体反応の機能解明と新規免疫学的治療の開発

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Development of new lung regeneration therapies by elucidating the lung regeneration mechanism of adipose tissue-derived stem cells

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胸腺上皮性腫瘍の腫瘍間質をターゲットとした治療戦略の探索

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The role of alveolar macrophages and regulatory pathways in post-transplant lung inflammation.

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本邦での心停止ドナー肺移植開始を目指したネクロプトーシス制御による臓器保護戦略

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肺癌の間質形成と肺線維化における線維芽細胞を標的とした新規免疫療法の基盤確立Principal Investigator

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New Therapeutic Strategy for Lung Cancer with Interstitial Lung DiseasesPrincipal Investigator

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間質性肺疾患における肺癌の増殖・転移の機序解明とCNPによる新たな治療戦略の探索Principal Investigator

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The development of a new therapy against interstitial lung disease using CNPPrincipal Investigator

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[Journal Article] Progressive changes in the protein expression profile of alveolar septa in early-stage lung adenocarcinoma2024

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[Journal Article] A Novel Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-Kappa B Activation Pathway is Involved in the Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemia-Reperfusion Lung Injury2024

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kimura toru 木村亨

Kimura Toru 木村亨