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Ieguchi Katsuaki  家口 勝昭

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家口 勝昭  イエグチ カツアキ

IEGUCHI Katsuaki  家口 勝昭

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Researcher Number 90586348
Other IDs
Affiliation (Current) 2025: 昭和大学, 大学共同利用機関等の部局等, 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 昭和大学, 大学共同利用機関等の部局等, 講師
2021: 昭和大学, 大学共同利用機関等の部局等, 講師
2016 – 2017: 東京女子医科大学, 医学部, 助教
2013 – 2014: 東京女子医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / General internal medicine(including psychosomatic medicine) / Respiratory surgery / Biological Sciences
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
ephrin / Eph / 転移 / PD-L1 / がん / 交感神経 / 免疫逃避 / 腫瘍微小環境 / ADAM12 / ephrin-A1 … More / EphA2 / 自律神経 / βブロッカー / 交感神経β受容体遮断薬 / 転移前微小環境 / 炎症性サイトカイン / ADAM / 造血幹細胞 / ノルエピネフリン / ノルアドレナリン / カテコラミン / 腫瘍 … More
Except Principal Investigator
増殖因子 / ケモカイン / 癌 / がん / 転移 / TLR / 内因性リガンド / 炎症 / ADAM12 / CCR2 / がん転移 / 自然免疫 / ephrinA1 / CCL2 / S100A8 / SAA3 / TLR4 Less
  • Research Projects

    (6 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (8 People)
  •  Analysis of EphA2/ephrin-A1-mediated PD-L1 expression and its clinical applicationPrincipal Investigator

    • Principal Investigator
      家口 勝昭
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Showa University
  •  Molecular mechanisms of EphA2/ephrin-A1-mediated immune escape in the tumor microenvironmentPrincipal Investigator

    • Principal Investigator
      Ieguchi Katsuaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Showa University
  •  Role of the sympathetic nervous system in metastasisPrincipal Investigator

    • Principal Investigator
      Ieguchi Katsuaki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Tokyo Women's Medical University
  •  交感神経による血管支配におけるephrin-A1の機能解析Principal Investigator

    • Principal Investigator
      家口 勝昭
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Women's Medical University
  •  Role of ephrin-A1 in lung metastasisPrincipal Investigator

    • Principal Investigator
      IEGUCHI Katsuaki
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory surgery
    • Research Institution
      Tokyo Women's Medical University
  •  Endogenous TLR4 ligands in tumor metastasis.

    • Principal Investigator
      MARU Yoshiro
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Women's Medical University

All 2016 2015 2014 2013 Other

All Journal Article Presentation Book

  • [Book] 血液内科2014

    • Author(s)
      家口勝昭、丸義朗
    • Total Pages
      7
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-25870760
  • [Journal Article] Savior or not: ADAM17 inhibitors overcome radiotherapy-resistance in non-small cell lung cancer2016

    • Author(s)
      Ieguchi K, Maru Y.
    • Journal Title

      J Thoracic Disease

      Volume: 8 Issue: 8 Pages: E813-E813

    • DOI

      10.21037/jtd.2016.07.56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15417
  • [Journal Article] Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor.2015

    • Author(s)
      Tomita T, Ieguchi K, Sawamura T, Maru Y
    • Journal Title

      PLoS One

      Volume: 10(3) Issue: 3 Pages: e0118835-e0118835

    • DOI

      10.1371/journal.pone.0118835

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25870760, KAKENHI-PROJECT-26440063
  • [Journal Article] LINGO-1 Protein Interacts with the p75 Neurotrophin Receptor in Intracellular Membrane Compartments2015

    • Author(s)
      Meabon JS, De Laat R, Ieguchi K, Wiley JC, Hudson MP, Bothwell M
    • Journal Title

      J Biol Chem

      Volume: 290(15) Issue: 15 Pages: 9511-20

    • DOI

      10.1074/jbc.m114.608018

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25870760
  • [Journal Article] ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor2014

    • Author(s)
      Tomita T, Ieguchi K, Coin F, Kato Y, Kikuchi H, Oshima Y, Kurata S, Maru Y
    • Journal Title

      PLoS One

      Volume: 30 Issue: 9 Pages: e108957-e108957

    • DOI

      10.1371/journal.pone.0108957

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390014, KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25870760, KAKENHI-PROJECT-26440063
  • [Journal Article] ADAM12-cleaved ephrin-A1 contributes to lung metastasis2014

    • Author(s)
      Ieguchi K, Tomita T, Omori T, Komatsu A, Deguchi A, Masuda J, Duffy S, Coulthard M, Boyd A, Maru Y
    • Journal Title

      Oncogene

      Volume: 33(17) Pages: 2179-2190

    • Data Source
      KAKENHI-PLANNED-21117008
  • [Journal Article] がん転移における炎症と血管新生2014

    • Author(s)
      家口勝昭、丸義朗
    • Journal Title

      血液内科

      Volume: 69(3) Pages: 349-55

    • Data Source
      KAKENHI-PUBLICLY-25122716
  • [Journal Article] ADAM12-cleaved ephrin-A1 contributes to lung metastasis.2014

    • Author(s)
      Ieguchi K, Tomita T, Omori T, Komatsu A, Deguchi A, Masuda J, Duffy SL, Coulthard MG, Boyd A, Maru Y.
    • Journal Title

      Oncogene

      Volume: 未定 Issue: 17 Pages: 2179-90

    • DOI

      10.1038/onc.2013.180

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590347, KAKENHI-PROJECT-24501321, KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25860797, KAKENHI-PROJECT-25870760, KAKENHI-PROJECT-26640079
  • [Journal Article] An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R2013

    • Author(s)
      Fujita M, Ieguchi K, Cedano-Prieto DM, Fong A, Wilkerson C, Chen JQ, Wu M, Lo SH, Cheung AT, Wilson MD, Cardiff RD, Borowsky AD, Takada YK, Takada Y
    • Journal Title

      Journal of Biological Chemistry

      Volume: 288 Issue: 27 Pages: 19593-19603

    • DOI

      10.1074/jbc.m113.470872

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25870760
  • [Journal Article] Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 42013

    • Author(s)
      Ieguchi K, Omori T, Komatsu A, Tomita T, Deguchi A, Maru Y
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 440(4) Pages: 623-629

    • Data Source
      KAKENHI-PLANNED-21117008
  • [Journal Article] Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 42013

    • Author(s)
      Ieguchi K, Omori T, Komatsu A, Tomita T, Deguchi A, Maru Y
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 440(4) Issue: 4 Pages: 623-629

    • DOI

      10.1016/j.bbrc.2013.09.119

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117008, KAKENHI-PROJECT-23590347, KAKENHI-PROJECT-24501321, KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25870760
  • [Presentation] Role of the sympathetic nervous system in lung metastasis2015

    • Author(s)
      Ieguchi, K. and Maru Y
    • Organizer
      2nd International symposium 2015 “Neuro-Vascular wiring”
    • Place of Presentation
      関西セミナーハウス(京都府・左京区)
    • Year and Date
      2015-01-18
    • Data Source
      KAKENHI-PUBLICLY-25122716
  • [Presentation] Breakdown of the Eph/ephrin system in vascular endothelial cells causes lung metastasis2014

    • Author(s)
      Ieguchi K, Tomita , Maru Y
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      京都市勧業館みやこめっせ(京都府・左京区)
    • Year and Date
      2014-04-16
    • Data Source
      KAKENHI-PROJECT-25870760
  • [Presentation] Breakdown of the Eph/ephrin system in vascular endothelial cells causes lung metastasis2014

    • Author(s)
      Ieguchi, K., Tomita, T. and Maru, Y
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      京都市勧業館みやこめっせ(京都府・左京区)
    • Year and Date
      2014-04-16
    • Data Source
      KAKENHI-PUBLICLY-25122716
  • [Presentation] ADAM12-cleaved ephrin-A1 contributes to lung metastasis2013

    • Author(s)
      Ieguchi Katsuaki, Tomita Takeshi, Yoshiro Maru
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PUBLICLY-25122716
  • [Presentation] ADAM12-cleaved ephrin-A1 contributes to lung metastasis.2013

    • Author(s)
      Ieguchi Katsuaki, Tomita Takeshi, Yoshiro Maru
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜、日本
    • Data Source
      KAKENHI-PLANNED-21117008
  • [Presentation] ADAM12-cleaved ephrin-A1 contributes to lung metastasis2013

    • Author(s)
      Ieguchi Katsuaki, Tomita Takeshi, Yoshiro Maru
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25870760
  • [Presentation] Role of the sympathetic nervous system in lung metastasis

    • Author(s)
      Ieguchi K, Maru Y
    • Organizer
      2nd International symposium 2015 “Neuro-Vascular wiring”
    • Place of Presentation
      関西セミナーハウス(京都府・左京区)
    • Year and Date
      2015-01-18 – 2015-01-19
    • Data Source
      KAKENHI-PROJECT-25870760
  • 1.  和田 聡 (30420102)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  MARU Yoshiro (00251447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  NAKAMURA Sachie (60313087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TSUKAHARA Fujiko (40119996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TOMITA Takeshi (20302242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 6.  DEGUCHI Atsuko (10422932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  TAKITA Morichika (80533455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  倉田 祥一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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