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Inoue Kenichi  井上 健一

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INOUE Ken-ichi  井上 健一

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Researcher Number 90587974
Other IDs
Affiliation (Current) 2025: 獨協医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 獨協医科大学, 医学部, 准教授
2012 – 2014: 獨協医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 90110:Biomedical engineering-related / Basic Section 51030:Pathophysiologic neuroscience-related / Pathological medical chemistry
Except Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 90110:Biomedical engineering-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 55020:Digestive surgery-related / Cardiovascular medicine / Urology
Keywords
Principal Investigator
ECM / サイトカイン / 線維芽細胞 / 好中球 / エージェントシミュレーション / Drug Repurposing / NEDAMSS病態モデル / 小児神経変性疾患 / 孤発性IRF2BPL変異 / ウェスト症候群 … More / 細胞内局在 / IRF2BP2 / IRF2BP1 / 疾患由来iPS細胞 / multivesicular body / lamellar body / アストログリア / 皮質ニューロン / 患者由来iPS細胞 / NEDAMSS / IRF2BPL / RUNX転写因子 / 神経芽腫 / ストレプトアビジンアプタマー / 次世代シーケンサー / microRNAクローニング / N-Myc / RUNX3 / RUNX1 / neuroblastoma / microRNA … More
Except Principal Investigator
Muse細胞 / 創傷治癒 / 再生医療 / 細胞間コミュニケーション / 蛍光免疫多重染色(OPAL法) / 癌関連線維芽細胞(CAF) / 急性心筋梗塞 / SSEA-3 / single cell RNA-seq解析 / SSEA-3陽性細胞 / 脂肪組織由来間質細胞 / マルチエージェントシミュレーション / 複雑系 / 細胞外マトリクス / 炎症性サイトカイン / 生体シミュレーション / muse細胞 / 妊産婦 / 疫学 / 糖尿病 / 予防医学 / 新規治療法確立 / 病態解明 / 心筋炎動物モデル / Muse細胞機能 / 急性心筋炎 / 皮下脂肪由来再生幹細胞 / 皮下脂肪組織由来再生幹細胞 / 移植 / 肛門括約筋障害 / ラット / 異系移植 / 同系移植 / 肛門内最大静止圧 / 脂肪組織由来間葉系幹細胞 / 肛門括約筋障害モデル動物 / 内肛門括約筋 / 間質血管細胞群 / 脂肪組織由来再生幹細胞 / 便失禁 / 脂肪由来間質細胞 / 血管新生 / 傷害刺激 / 間質細胞 / 転写因子 / 排尿機能 / レンチウイルスベクター / iPS干渉法 / 尿路上皮 / ハンナー病変 / 膀胱上皮幹細胞 / ダイレクトリプログラミング / リプログラミング / パイオニア因子 / 主成分分析 / ハンナ型・非ハンナ型 / マスター転写因子 / 間質性膀胱炎 Less
  • Research Projects

    (11 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (20 People)
  •  進行大腸癌の再発メカニズムを細胞間コミュニケーションから紐解く

    • Principal Investigator
      岸本 聡子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Dokkyo Medical University
  •  エージェントシミュレーションを活用した慢性炎症・臓器線維化のメカニズム追求Principal Investigator

    • Principal Investigator
      井上 健一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Dokkyo Medical University
  •  急性心筋梗塞患者の末梢血で増加するMUSE細胞のプロファイル

    • Principal Investigator
      佐久間 理吏
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Dokkyo Medical University
  •  細胞社会は互いのコミュニケーションをどのようにとっているか:複雑系の視点

    • Principal Investigator
      岸本 聡子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Dokkyo Medical University
  •  In vitro model of NEDAMSS pathology using patients-derived iPS cells with sporadic IRF2BPL mutationPrincipal Investigator

    • Principal Investigator
      Inoue Kenichi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Dokkyo Medical University
  •  Muse細胞を用いた急性心筋炎の病態解明および新規治療法確立

    • Principal Investigator
      井上 晃男
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Dokkyo Medical University
  •  Exploratory cell histological and epidemiological research of Muse cell for prevention

    • Principal Investigator
      Kobashi Gen
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Dokkyo Medical University
  •  Development of treatment for fecal incontinence using non-cultured human adipose derived mesenchymal stem cells.

    • Principal Investigator
      Ishizuka Mitsuru
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Dokkyo Medical University
  •  Synergistic Cooperation of Heterogeneous Stromal Cells for Wound Repair Priming

    • Principal Investigator
      Kishimoto Satoko
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Dokkyo Medical University
  •  Identification of urothelial master transcription factors diminished in interstitial cystitis

    • Principal Investigator
      Yamanishi Tomonori
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Dokkyo Medical University
  •  Post-transcriptional regulation of RUNX1/RUNX3 is critical for neuroblastoma cell growth or differentiation.Principal Investigator

    • Principal Investigator
      INOUE Ken-ichi
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Dokkyo Medical University

All 2024 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Endothelial Regeneration in Repair from Vascular Injury and Stem Cell Biology2022

    • Author(s)
      Teruo Inoue, Daniel Simon, Toyoaki Murohara, Mari Dezawa, Kenichi Inoue, Masashi Sakuma, Shigeru Toyoda
    • Journal Title

      Dokkyo Medical Journal

      Volume: 1 Pages: 4-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08496
  • [Journal Article] Muse cell research focuses on patients2021

    • Author(s)
      Teruo Inoue, Daniel Simon, Toyoaki Murohara, Shigeru Toyoda, Mari Dezawa, Kenichi Inoue, Masashi Sakuma
    • Journal Title

      Impact

      Volume: 1 Pages: 16-18

    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08496
  • [Journal Article] Surgical Injury and Ischemia Prime the Adipose Stromal Vascular Fraction and Increase Angiogenic Capacity in a Mouse Limb Ischemia Model2020

    • Author(s)
      Kishimoto S, Inoue KI, Sohma R, Toyoda S, Sakuma M, Inoue T, Yoshida K
    • Journal Title

      Stem Cells International

      Volume: 7219149 Pages: 7219149-7219149

    • DOI

      10.1155/2020/7219149

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Journal Article] Cancer-associated fibroblasts show heterogeneous gene expression and induce vascular endothelial growth factor A (VEGFA) in response to environmental stimuli2019

    • Author(s)
      Inoue KI, Kishimoto S, Akimoto K, Sakuma M, Toyoda S, Inoue T, Yoshida KI, Shimoda M, Suzuki S
    • Journal Title

      Ann Gastroenterol Surg

      Volume: 3 Issue: 4 Pages: 416-425

    • DOI

      10.1002/ags3.12249

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Journal Article] Surgical Injury and Ischemia Prime the Adipose Stromal Vascular Fraction and Increases Angiogenic Capacity in a Mouse Limb Ischemia Model2019

    • Author(s)
      Kishimoto S, Inoue KI, Sohma R, Toyoda S, Sakuma M, Inoue T, Yoshida KI
    • Journal Title

      Stem Cells International

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Journal Article] Autologous and heterotopic transplantation of adipose stromal vascular fraction ameliorates stress urinary incontinence in rats with simulated childbirth trauma2018

    • Author(s)
      Ken-ichi Inoue, Satoko Kishimoto, Kanya Kaga, Miki Fuse, Akira Furuta, Tomonori Yamanishi
    • Journal Title

      Regenerative Therapy

      Volume: 8 Pages: 9-14

    • DOI

      10.1016/j.reth.2017.11.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Journal Article] Reproducible insulin secretion from isolated rat pancreas preparations using an organ bath2018

    • Author(s)
      Asuka Morita, Motoshi Ouchi, Misao Terada, Hiroe Kon, Satoko Kishimoto, Keitaro Satoh, Naoyuki Otani, Keitaro Hayashi, Tomoe Fujita, Ken-ichi Inoue, Naohiko Anzai
    • Journal Title

      Exp. Anim.

      Volume: 67 Issue: 1 Pages: 15-22

    • DOI

      10.1538/expanim.17-0059

    • NAID

      130006339985

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Journal Article] Low-Molecular Weight Heparin/Protamine Micro-Nanoparticles Augmented Viability of Human Adipose-Derived Regenerative Cells.2018

    • Author(s)
      Masashi Sakuma, Satoko Kishimoto, Ken-ichi Inoue, Ryoichi Sohma, Shigeru Toyoda, Hideki Iwaguro and Teruo Inoue
    • Journal Title

      Biomedical Journal of Scientific and Technical Research

      Volume: 12 Issue: 3 Pages: 1-3

    • DOI

      10.26717/bjstr.2018.12.002265

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Journal Article] Expression profile of urothelial transcription factors in bladder biopsies with interstitial cystitis2017

    • Author(s)
      Kanya Kaga, Ken-ichi Inoue, Mayuko Kaga, Tomohiko Ichikawa, Tomonori Yamanishi
    • Journal Title

      International Journal of Urology

      Volume: 24 Issue: 8 Pages: 632-638

    • DOI

      10.1111/iju.13391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K11059
  • [Presentation] Differentiation of NEDAMSS derived iPS cells to neural stem cells and astrocytes.2024

    • Author(s)
      Ken-ichi INOUE
    • Organizer
      IRF2BPL consortium research meeting 2024
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07763
  • [Presentation] 脂肪組織由来間葉系幹細胞移植による内肛門括約筋機能障害改善効果2022

    • Author(s)
      石塚 満、井上 健一、岸本 聡子、山西 友典、布施 美樹、 鎌迫 智彦、加賀 勘家、清水 崇行、青木 琢、 窪田 敬一
    • Organizer
      第21回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-19K09155
  • [Presentation] 内肛門括約筋機能障害改善を目的とした脂肪組織由来間葉系幹細胞移植の効果2022

    • Author(s)
      石塚 満、井上 健一、岸本 聡子、山西 友典、布施 美樹、 鎌迫 智彦、加賀 勘家、加賀 麻祐子、清水 崇行、青木 琢、 窪田 敬一
    • Organizer
      第122回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19K09155
  • [Presentation] 便失禁治療への応用を目指した脂肪組織由来再生幹細胞移植による内肛門括約筋機能障害改善効果の検討2021

    • Author(s)
      石塚 満、井上 健一、岸本 聡子、山西 友典、布施 美樹、 鎌迫 智彦、加賀 勘家、加賀 麻祐子、清水 崇行、窪田 敬一
    • Organizer
      第26回大腸肛門機能障害研究会
    • Data Source
      KAKENHI-PROJECT-19K09155
  • [Presentation] 脂肪組織由来再生幹細胞移植による内肛門括約筋機能障害改善効果の検討2021

    • Author(s)
      石塚 満、井上 健一、岸本 聡子、山西 友典、布施 美樹、 鎌迫 智彦、清水 崇行、青木 琢、窪田 敬一
    • Organizer
      第76回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09155
  • [Presentation] 脂肪組織由来再生幹細胞移植による内肛門括約筋機能障害改善効果の検討2021

    • Author(s)
      石塚 満、井上 健一、岸本 聡子、山西 友典、布施 美樹、 鎌迫 智彦、加賀 勘家、加賀 麻祐子、清水 崇行、青木 琢、 窪田 敬一
    • Organizer
      JDDW2021 消化器病学会
    • Data Source
      KAKENHI-PROJECT-19K09155
  • [Presentation] ハンナ型と非ハンナ型間質性膀胱炎の分子生物学的相違2019

    • Author(s)
      加賀勘家、井上健一、加賀麻祐子、布施美樹、石塚満、山西友典
    • Organizer
      第18回日本間質性膀胱炎研究会
    • Data Source
      KAKENHI-PROJECT-16K11059
  • [Presentation] 組織間質細胞の修復戦略を細胞社会の文脈で理解する2018

    • Author(s)
      井上健一, 岸本聡子, 井上晃男, 吉田謙一郎
    • Organizer
      第17回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Presentation] 創傷治癒における間質細胞の傷害刺激感知と血管新生増強2017

    • Author(s)
      岸本聡子, 井上健一, 朝戸裕貴, 井上晃男, 吉田謙一郎
    • Organizer
      第47回日本創傷治癒学会
    • Data Source
      KAKENHI-PROJECT-17K09559
  • [Presentation] Expression profile of urothelial transcription factors in bladder biopsies with interstitial cystitis2017

    • Author(s)
      Kanya Kaga, Ken-ichi Inoue, Mayuko Kaga, Miki Fuse, Tomonori Yamanishi
    • Organizer
      International Continence Society 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11059
  • [Presentation] 膀胱移行上皮マスター転写因子のスクリーニング2017

    • Author(s)
      井上健一, 山西友典, 加賀勘家, 井上晃男, 吉田謙一郎
    • Organizer
      第16回日本再生医療学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Data Source
      KAKENHI-PROJECT-16K11059
  • 1.  Kishimoto Satoko (10511488)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 12 results
  • 2.  井上 晃男 (20168454)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 3.  相馬 良一 (20868054)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  出沢 真理 (50272323)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  Yamanishi Tomonori (90220425)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 6.  Ishizuka Mitsuru (20382963)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 7.  佐久間 理吏 (10530199)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 8.  串田 良祐 (10707003)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  張山 昌論 (10292260)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  Kobashi Gen (60270782)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  加賀 勘家 (80584812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 12.  清水 崇行 (50622198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 13.  窪田 敬一 (70260388)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 14.  中舘 和彦 (80372895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  山内 忍 (70433589)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  正和 泰斗 (70870195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  豊田 茂 (80332998)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  内山 浩志 (00711318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  春山 康夫 (20406185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  高倉 聡 (60256401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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