SHIMOJO Masahito 下條正仁

Researcher Number	90591925
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院薬学研究科, 特任准教授(常勤) 2015: 大阪医科大学, 医学部, 講師 2012 – 2014: 関西医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Respiratory organ internal medicine / Pain science
Keywords	Principal Investigator miRNA / 小細胞肺がん / スプライシング制御 / 個別化医療 / コンパニオン診断薬 / アンチセンス核酸 / 核酸医薬 / nSR100 / 小細胞肺癌 / 神経因性疼痛 / スプライシング / 転写因子 / 神経障害性疼痛

Research on personalized medicine using miR-4516 and antisense oligonucleotide for treating refractory neuroendocrine cancerPrincipal Investigator
- Principal Investigator
  
  下條正仁
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Osaka University
Study of novel diagnostic tests and treatment of small cell lung cancer.Principal Investigator
- Principal Investigator
  
  Shimojo Masahito
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka Medical College
  Kansai Medical University
Study of the neuron-specific alternative splicing in neuropathic painPrincipal Investigator
- Principal Investigator
  
  SHIMOJO Masahito
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pain science
- Research Institution
  Kansai Medical University

All 2023 2015 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] The small cell lung cancer-specific isoform of RE1-silencing transcription factor (REST) is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100).2013
- Author(s)
  Shimojo M, Shudo Y, Ikeda M, Kobashi T, Ito S.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 11 Issue: 10 Pages: 1258-1268
- DOI
  10.1158/1541-7786.mcr-13-0269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659295
[Patent] DIAGNOSTIC DRUG AND THERAPEUTIC DRUG FOR SMALL LUNG CANCER2014
- Inventor(s)
  SHIMOJO, Masahito
- Industrial Property Rights Holder
  学校法人関西医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-16
- Overseas
- Data Source
  KAKENHI-PROJECT-26670423
[Presentation] Splice-switching antisense oligonucleotide controlling tumor suppressor REST as a novel therapeutic medicine for neuroendocrine cancer2023
- Author(s)
  Masahito Shimojo, Keishiro Mishima, Satoshi Obika
- Organizer
  The 40th Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07230
[Presentation] Splice-switching antisense oligonucleotide controls the tumor suppressor REST - novel therapeutic medicine for NE cancer -2023
- Author(s)
  Masahito Shimojo
- Organizer
  The 82nd Annual Meeting of the Japanese Cancer Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07230
[Presentation] Selective siRNA-mediated suppression of nSR100 (SRRM4) induces the cell death of small cell lung cancer.2015
- Author(s)
  Shimojo M. Shudo Y. Ito S.
- Organizer
  45th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670423
[Presentation] Selective siRNA-mediated suppression of nSR100 (SRRM4) induces the cell death of small cell lung cancer.2015
- Author(s)
  Shimojo M. Shudo Y.
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場、兵庫
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26670423
[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013
- Author(s)
  Shudo Y., Shimojo M., Ito S.
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24659295
[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013
- Author(s)
  Shudo Y, Shimojo M, Ito S.
- Organizer
  Society for Neuroscience
- Place of Presentation
  神戸コンベンションセンター（兵庫県）
- Data Source
  KAKENHI-PROJECT-24659295
[Presentation] Small cell lung cancer (SCLC)-specific RE1-silencing transcription factor (REST) isoform is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100/SRRM4)2013
- Author(s)
  Shimojo M, Shudo Y, Ito S
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸コンベンションセンター（兵庫県）
- Data Source
  KAKENHI-PROJECT-24659295
[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013
- Author(s)
  Shudo Y, Shimojo M, Ito S.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Convention Center (San Diego, USA)
- Data Source
  KAKENHI-PROJECT-24659295
[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013
- Author(s)
  Shudo Y., Shimojo M., Fukunaga M., Ito S.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24659295
[Presentation] Small cell lung cancer (SCLC)-specific RE1-silencing transcription factor (REST) isoform is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100/SRRM4)2013
- Author(s)
  Shimojo M, Shudo Y, Ito S
- Organizer
  Society for Neuroscience
- Place of Presentation
  Convention Center (San Diego, USA)
- Data Source
  KAKENHI-PROJECT-24659295
[Presentation] Identification of small cell lung cancer (SCLC)-specific miRNAs in blood as a tumor marker for the detection of SCLC.
- Author(s)
  Shimojo M. Shudo Y. Ito S.
- Organizer
  44th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26670423
[Presentation] Identification of small cell lung cancer (SCLC)-specific miRNAs in blood as a tumor marker for the detection of SCLC.
- Author(s)
  下條正仁, 首藤由江, 伊藤誠二
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26670423

1. ITO Seiji (80201325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. NOMURA Shosaku (20218358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KURATA Takayasu (40340781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMOJO Masahito 下條 正仁

Research Projects

Research Products

Co-Researchers

Research on personalized medicine using miR-4516 and antisense oligonucleotide for treating refractory neuroendocrine cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of novel diagnostic tests and treatment of small cell lung cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of the neuron-specific alternative splicing in neuropathic painPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The small cell lung cancer-specific isoform of RE1-silencing transcription factor (REST) is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100).2013

Author(s)

Journal Title

DOI

Data Source

[Patent] DIAGNOSTIC DRUG AND THERAPEUTIC DRUG FOR SMALL LUNG CANCER2014

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Splice-switching antisense oligonucleotide controlling tumor suppressor REST as a novel therapeutic medicine for neuroendocrine cancer2023

Author(s)

Organizer

Data Source

[Presentation] Splice-switching antisense oligonucleotide controls the tumor suppressor REST - novel therapeutic medicine for NE cancer -2023

Author(s)

Organizer

Data Source

[Presentation] Selective siRNA-mediated suppression of nSR100 (SRRM4) induces the cell death of small cell lung cancer.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Selective siRNA-mediated suppression of nSR100 (SRRM4) induces the cell death of small cell lung cancer.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Small cell lung cancer (SCLC)-specific RE1-silencing transcription factor (REST) isoform is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100/SRRM4)2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Pituitary adenylate-cyclase activating polypeptide (PACAP) is possibly regulated by RE1-silencing transcription factor (REST/NRSF) isoform in neuropathic pain2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Small cell lung cancer (SCLC)-specific RE1-silencing transcription factor (REST) isoform is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100/SRRM4)2013

Author(s)

SHIMOJO Masahito 下條正仁