MIKAMI Toshihiko 三上俊彦

Researcher Number	90595745
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2022: 新潟大学, 医歯学系, 非常勤研究員 2019 – 2020: 新潟大学, 医歯学系, 助教 2016: 新潟大学, 医歯学系, 助教 2015: 新潟大学, 医歯学総合病院, 特任助教 2013 – 2015: 新潟大学, 医歯学総合病院, 助教 2012 – 2013: 新潟大学, 医歯学総合病院, 特任助教
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Keywords	Principal Investigator 口腔扁平上皮癌 / 14-3-3 sigma / keratin 17 / 上皮内癌 / 癌関連線維芽細胞(CAF) / 頸部リンパ節転移 / 癌関連線維芽細胞 / Keratin17 / mTOR / Keratin 17 / siRNA … More Except Principal Investigator … More 浸潤能 / SOX9 / TGF-β / 癌微小環境 / 口腔癌 / 癌関連線維芽細胞 / ＰＣＲ / 骨密度 / マイクロCT / ラット実験モデル / 下顎骨延長 / 発症メカニズム / 顎変形症 / 骨代謝マーカー / 骨粗鬆症ラット / 骨強度 / PCR Less

Analysis of the function of cancer-associated fibroblasts (CAFs) in the invasion of oral cancer.
- Principal Investigator
  
  Funayama Akinori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Niigata University
The novel therapeutic strategy for oral cancer targeting cancer-asssociated fibroblastPrincipal Investigator
- Principal Investigator
  
  MIKAMI Toshihiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Niigata University
Keratin 17 controls cancer characteristics in oral mucosa: Analysis of the mechanisms of oncogenesis through the mTOR signalingPrincipal Investigator
- Principal Investigator
  
  MIKAMI Toshihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Niigata University
Clarification of risk factors for progressive condylar resorption and development of prevention method with intermittent PTH(1-34) treatment
- Principal Investigator
  
  Kobayashi Tadaharu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Niigata University
Keratin 17 promotes the activity of the oral squamous cell carcinoma cell: Comparison analysis with the behavior of 14-3-3 sigmaPrincipal Investigator
- Principal Investigator
  
  MIKAMI Toshihiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Niigata University

All 2021 2020 2019 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Crosstalk between oral squamous cell carcinoma cells and cancer-associated fibroblasts via the TGF-β/SOX9 axis in cancer progression2021
- Author(s)
  Haga Kenta、Yamazaki Manabu、Maruyama Satoshi、Kawaharada Masami、Suzuki Ayako、Hoshikawa Emi、Chan Nyein Nyein、Funayama Akinori、Mikami Toshihiko、Kobayashi Tadaharu、Izumi Kenji、Tanuma Jun-ichi
- Journal Title
  
  Translational Oncology
  
  Volume: 14 Issue: 12 Pages: 101236-101236
- DOI
  10.1016/j.tranon.2021.101236
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10069, KAKENHI-PROJECT-19K10329, KAKENHI-PROJECT-21K09856, KAKENHI-PROJECT-21K10109
[Journal Article] Relationships among maxillofacial morphologies, bone properties and bone metabolic markers in patients with jaw deformities.2016
- Author(s)
  Daisuke Saito, Toshihiko Mikami, Yohei Oda, Daichi Hasebe, Hideyoshi Nishiyama, Isao Saito, Tadaharu Kobayashi
- Journal Title
  
  Int J Oral Maxillofac Surg.
  
  Volume: 印刷中 Issue: 8 Pages: 985-991
- DOI
  10.1016/j.ijom.2016.02.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25463074
[Journal Article] Keratin 17 is co-expressed with 14-3-3 sigma in oral carcinoma in situ and squamous cell carcinoma and modulates cell proliferation and size but not cell migration.2015
- Author(s)
  Mikami T, Maruyama S, Abe T, Kobayashi T, Yamazaki M, Funayama A, Shingaki S, Kobayashi T, Jun C, Saku T.
- Journal Title
  
  Virchows Arch.
  
  Volume: 466(5) Issue: 5 Pages: 559-69
- DOI
  10.1007/s00428-015-1735-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592829, KAKENHI-PROJECT-25861740, KAKENHI-PROJECT-26305032, KAKENHI-PROJECT-15K15693, KAKENHI-PROJECT-26861706, KAKENHI-PROJECT-25462849, KAKENHI-PROJECT-25305035
[Presentation] Cancer-associated fibroblasts promote the invasion of oral squamous cell carcinoma cells via the TGF-β/SOX9 axis2020
- Author(s)
  Kenta Haga，Manabu Yamazaki, Satoshi Maruyama, Ayako Suzuki, Emi Hoshikawa, Akinori Funayama, Toshihiko Mikami, Tadaharu Kobayashi , Kenji Izumi, Jun-ichi Tanuma
- Organizer
  The International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment
- Data Source
  KAKENHI-PROJECT-19K10329
[Presentation] 関連線維芽細胞は口腔扁平上皮癌においてTGF-β/SOX9経路介して遊走および浸潤を促進する2020
- Author(s)
  羽賀健太，山崎学，船山昭典，金丸祥平，三上俊彦，新美奏恵，小林正治，田沼順一
- Organizer
  第74回 NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10329
[Presentation] 癌関連線維芽細胞による口腔扁平上皮癌の遊走および浸潤の制御機構の役割2020
- Author(s)
  羽賀健太, 山崎学, 丸山智, 船山昭典, 三上俊彦,小林正治, 田沼順一
- Organizer
  第64回公益社団法人　日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10329
[Presentation] 癌関連線維芽細胞は口腔扁平上皮癌細胞の遊走および浸潤を促進する-3次元培養モデルを用いた検討-2019
- Author(s)
  羽賀健太，山崎学，丸山智，鈴木絢子，干川絵美，船山昭典，三上俊彦，田沼順一，小林正治，泉健次
- Organizer
  第79回新潟癌治療研究会
- Data Source
  KAKENHI-PROJECT-19K10329
[Presentation] がん関連線維芽細胞は口腔扁平上皮癌においてSOX9発現を増強させ浸潤を促進する2019
- Author(s)
  羽賀健太，山崎学，丸山智，鈴木絢子，干川絵美，船山昭典，三上俊彦，小林正治，泉健次，田沼順一
- Organizer
  令和元年度新潟歯学会第2回例会
- Data Source
  KAKENHI-PROJECT-19K10329
[Presentation] 癌関連線維芽細胞は口腔扁平上皮癌においてSOX9を高発現させ遊走および浸潤を促進する2019
- Author(s)
  羽賀健太，山崎学，丸山智，船山昭典，金丸祥平，三上俊彦，新美奏恵，小林正治，田沼順一
- Organizer
  第64回公益社団法人　日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10329
[Presentation] 顎変形症患者における顎顔面形態と骨代謝ならびに骨質の評価2015
- Author(s)
  齋藤大輔，三上俊彦，小田陽平，長谷部大地，西山秀昌，齋藤　功，小林正治
- Organizer
  第69回日本口腔科学会学術集会
- Place of Presentation
  大阪国際会議場、（大阪府大阪市）
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-25463074
[Presentation] 顎変形症患者における顎顔面形態と骨代謝マーカーならびに骨密度との関連性2014
- Author(s)
  齋藤大輔，三上俊彦，小田陽平，長谷部大地，西山秀昌，小林正治
- Organizer
  平成26年度新潟歯学会第二回例会
- Place of Presentation
  新潟大学
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PROJECT-25463074
[Presentation] Coordinated expression of keratin17 and 14-3-3 sigma regulates in cell proliferation and migration of oral squamous cell carcinoma2013
- Author(s)
  Mikami T, Maruyama S, Cheng J, Kobayashi T, Funayama A, Yoshizawa M, Kobayashi T, Shingaki S, Saito C, Saku T
- Organizer
  21st International Conference on Oral and Maxillofacial Surgery
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24792185
[Presentation] Risk factors for progressive condylar resorption after mandibular advancement2013
- Author(s)
  Kobayashi T, Hasebe D, KojimaT, Funayama A, Mikami T, Niimi K, Yoshizawa M, Saito C
- Organizer
  21st International Conference on Oral and Maxillofacial Surgery
- Place of Presentation
  Palau de Congressos de Catalunya, Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-25463074
[Presentation] Coordinated expression of keratin17 and 14-3-3 sigma regulates in cell proliferation and migration of oral squamous cell carcinoma.2013
- Author(s)
  Mikami T, Maruyama S, Cheng J, Kobayashi T, Funayama A, Yoshizawa M, Kobayashi T, Shingaki S, Saito C, Saku T
- Organizer
  21st International Conference on Oral and Maxillofacial Surgery, 10/21-24, 2013.
- Place of Presentation
  Barcelona, Spain.
- Data Source
  KAKENHI-PROJECT-24792185
[Presentation] 顎変形症患者における顎顔面形態と骨代謝ならびに骨質の評価
- Author(s)
  齋藤大輔、三上俊彦、小田陽平、長谷部大地、西山秀昌、齋藤功、小林正治
- Organizer
  第69回日本口腔科学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-05-13 – 2015-05-15
- Data Source
  KAKENHI-PROJECT-25463074

1. FUNAYAMA AKINORI (80529686)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. Kobayashi Tadaharu (80195792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. KOJIMA TAKU (90515777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. INOUE KAYOKO (90303130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田沼順一 (20305139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. 泉健次 (80242436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 新美奏恵 (20397136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMAZAKI Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. ABE Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 丸山智

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 朔敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIKAMI Toshihiko 三上 俊彦

Research Projects

Research Products

Co-Researchers

Analysis of the function of cancer-associated fibroblasts (CAFs) in the invasion of oral cancer.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The novel therapeutic strategy for oral cancer targeting cancer-asssociated fibroblastPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Keratin 17 controls cancer characteristics in oral mucosa: Analysis of the mechanisms of oncogenesis through the mTOR signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of risk factors for progressive condylar resorption and development of prevention method with intermittent PTH(1-34) treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Keratin 17 promotes the activity of the oral squamous cell carcinoma cell: Comparison analysis with the behavior of 14-3-3 sigmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Crosstalk between oral squamous cell carcinoma cells and cancer-associated fibroblasts via the TGF-β/SOX9 axis in cancer progression2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relationships among maxillofacial morphologies, bone properties and bone metabolic markers in patients with jaw deformities.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Keratin 17 is co-expressed with 14-3-3 sigma in oral carcinoma in situ and squamous cell carcinoma and modulates cell proliferation and size but not cell migration.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Cancer-associated fibroblasts promote the invasion of oral squamous cell carcinoma cells via the TGF-β/SOX9 axis2020

Author(s)

Organizer

Data Source

[Presentation] 関連線維芽細胞は口腔扁平上皮癌においてTGF-β/SOX9経路介して遊走および浸潤を促進する2020

Author(s)

Organizer

Data Source

[Presentation] 癌関連線維芽細胞による口腔扁平上皮癌の遊走および浸潤の制御機構の役割2020

Author(s)

Organizer

Data Source

[Presentation] 癌関連線維芽細胞は口腔扁平上皮癌細胞の遊走および浸潤を促進する-3次元培養モデルを用いた検討-2019

Author(s)

Organizer

Data Source

[Presentation] がん関連線維芽細胞は口腔扁平上皮癌においてSOX9発現を増強させ浸潤を促進する2019

Author(s)

Organizer

Data Source

[Presentation] 癌関連線維芽細胞は口腔扁平上皮癌においてSOX9を高発現させ遊走および浸潤を促進する2019

Author(s)

Organizer

Data Source

[Presentation] 顎変形症患者における顎顔面形態と骨代謝ならびに骨質の評価2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 顎変形症患者における顎顔面形態と骨代謝マーカーならびに骨密度との関連性2014

MIKAMI Toshihiko 三上俊彦