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shigeyama masato  重山 昌人

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Shigeyama Masato  重山 昌人

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Researcher Number 90598327
Affiliation (Current) 2025: 岐阜医療科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2014 – 2017: 横浜薬科大学, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Medical systems
Except Principal Investigator
Risk sciences of radiation and chemicals
Keywords
Principal Investigator
がん指向性ナノチューブ / アネキシンV染色 / ナノカーボンチューブ / ナノ粒子 / 音響化学療法 / アポトーシス / がん指向性カーボンナノチューブ / 超音波
Except Principal Investigator
Real-time PCR / 個人差 … More / 遺伝子発現量 / シトクロムP450 / 加水分解反応 / フタル酸ブチルベンジル / UDP-グルクロン酸転移酵素 / フタル酸モノ-2-エチルへキシル / フタル酸ジ-2-エチルへキシル / UGT / グルクロン酸抱合反応 / フタル酸モノ-2-エチルへキシル(MEHP) / UDP-グルクロン酸転移酵素(UGT) / シトクロムP450(CYP) / ヒトiPS細胞 / 異物代謝酵素 / リスク評価法 / 曝露経路依存的 / 化学物質 Less
  • Research Projects

    (2 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (12 People)
  •  Development of Novel Antitumor Treatment by Sonodynamically Activated Cancer-oriented Carbon NanotubesPrincipal Investigator

    • Principal Investigator
      Shigeyama Masato
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical systems
    • Research Institution
      Yokohama College of Pharmacy
  •  Development of risk evaluation method for environmental chemicals based on the exposure routes

    • Principal Investigator
      Hanioka Nobumitsu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Yokohama College of Pharmacy

All 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys:contribution of UGT1A1,UGT1A8 and UGT1A92016

    • Author(s)
      Naoki Kishi, Akane Takasuka,Yuki Kokawa,Takashi Isobe, Maho Taguchi, Mikio Murata, Masato Shigeyama, Manabu Suno, Nobumitsu Hanioka
    • Journal Title

      Xenobiotica

      Volume: 46 Pages: 289-295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K01343
  • [Journal Article] Raloxifene and Yoshifumi Murata, Adsorption of histones on natural polysaccharides: the potential as agent for multiple organ failure in sepsis2016

    • Author(s)
      Takashi Isobe, Kyoko Kofuji, Kenji Okada, Junya Fujimori, Mikio Murata, Masato Shigeyama, Nobumitsu Hanioka, Yoshifumi Murata
    • Journal Title

      International Journal of Biological Macromolecules

      Volume: 84 Pages: 54-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K01343
  • [Journal Article] Adsorption of histones on natural polysaccharides: The potential as agent for multiple organ failure in sepsis2016

    • Author(s)
      Isobe T, Kofuji K, Okada K, Fujimori J, Murata M, Shigeyama M, Hanioka N, Murata Y
    • Journal Title

      International Journal of Biological Macromolecules

      Volume: 84 Pages: 54-57

    • DOI

      10.1016/j.ijbiomac.2015.11.029

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26860116, KAKENHI-PROJECT-26281028
  • [Journal Article] Functional characterization of cynomolgus monkey UDP-glucuronosyltransferase 1A92014

    • Author(s)
      Yamamoto K, Mukai M, Nagaoka K, Hayashi K, Hichiya H, Okada K, Murata M, Shigeyama M, Narimatsu S, Hanioka N
    • Journal Title

      Eur J Drug Metab Pharmacokinet

      Volume: 39 Issue: 3 Pages: 195-202

    • DOI

      10.1007/s13318-014-0177-x

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281028
  • [Journal Article] In vitro glucuronidation of propofol in microsomal fractions from human liver, intestine and kidney: tissue distribution and physiological role of UGT1A92014

    • Author(s)
      Mukai M, Tanaka S, Yamamoto K, Murata M, Okada K, Isobe T, Shigeyama M, Hichiya H, Hanioka N
    • Journal Title

      Pharmazie

      Volume: 69 Pages: 829-832

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281028
  • [Journal Article] Butylbenzyl phthalate hydrolysis in liver microsomes of humans, monkeys, dogs, rats and mice.2014

    • Author(s)
      Takahara Y, Kinashi Y, Takahara Y, Hichiya H, Okada K, Murata M, Shigeyama M, Hanioka N
    • Journal Title

      Biol Pharm Bull

      Volume: 37 Pages: 703-706

    • NAID

      130005468756

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281028
  • [Presentation] ソルビトールを添加することで塗布性を改善した新処方モーズペーストの臨床使用の1例2016

    • Author(s)
      橋口宏司、田口真穂、菊池絵里、飯村仁美、横山 敦、久保雅恵、後藤圭一、藤澤 順、重山昌人、寺町ひとみ
    • Organizer
      第10回日本緩和医療薬学会年会
    • Place of Presentation
      金沢
    • Year and Date
      2016-06-03
    • Data Source
      KAKENHI-PROJECT-15K01343
  • [Presentation] Mohs'ペーストに関する研究(第12報)-マウス腫瘍に対する効果2016

    • Author(s)
      田口真穂、伊東奈保美、小川法子、高橋千里、村田実希郎、山本 浩充、重山昌人、寺町ひとみ
    • Organizer
      第26回日本医療薬学会
    • Place of Presentation
      京都
    • Year and Date
      2016-09-17
    • Data Source
      KAKENHI-PROJECT-15K01343
  • [Presentation] Mohs'ペーストに関する研究(第11報)-処方改良Mohs'ペーストの物性と効能評価2016

    • Author(s)
      中村友哉、伊東奈保美、小川法子、高橋千里、田口真穂、重山昌人、寺町ひとみ、山本 浩充
    • Organizer
      日本薬剤会31年会
    • Place of Presentation
      岐阜
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-15K01343
  • [Presentation] 新規製剤設計を行ったソルビトール添加Mohsペーストを使用した3症例2016

    • Author(s)
      菊池絵里、田口真穂、橋口宏司、藤澤 順、重山昌人、寺町ひとみ
    • Organizer
      第25回日本創傷・オストミー・失禁管理学会
    • Place of Presentation
      浜松
    • Year and Date
      2016-06-11
    • Data Source
      KAKENHI-PROJECT-15K01343
  • [Presentation] 敗血症性多臓器不全に対する予防製剤への天然多糖類の利用に関する検討2015

    • Author(s)
      礒部隆史,岡田賢二,村田実希郎,津田泰之,埴岡伸光,小藤恭子,重山昌人,村田慶史
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25
    • Data Source
      KAKENHI-PROJECT-26281028
  • [Presentation] プロポフォールの肝ミクロゾームによるグルクロン酸抱合反応の種差2015

    • Author(s)
      埴岡伸光,向井麻莉奈,村田実希郎,重山昌人,岡田賢二,礒部隆史
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25
    • Data Source
      KAKENHI-PROJECT-26281028
  • [Presentation] フタル酸ブチルベンジルの加水分解反応の種差:ヒト、サル、イヌ、ラット及びマウス肝ミクロゾームによる速度論的解析2014

    • Author(s)
      高原有香,鬼無悠,高原佑輔,岡田賢二,村田実希郞,重山昌人,比知屋寛之,埴岡伸光
    • Organizer
      第41回日本毒性学会学術年会
    • Place of Presentation
      神戸
    • Year and Date
      2014-07-02
    • Data Source
      KAKENHI-PROJECT-26281028
  • [Presentation] プロポフォールのヒト肝臓、小腸及び腎臓ミクロゾームによるグルクロン酸抱合反応:UGT1A9の組織分布性と役割2014

    • Author(s)
      向井麻莉奈,田中佐和子,山本康平,村田実希郎,岡田賢二,重山昌人,比知屋寛之,埴岡伸光
    • Organizer
      第41回日本毒性学会学術年会
    • Place of Presentation
      神戸
    • Year and Date
      2014-07-02
    • Data Source
      KAKENHI-PROJECT-26281028
  • 1.  Hanioka Nobumitsu (70228518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 2.  MURATA MIKIO (80723478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 3.  HICHIYA HIROYUKI (20548820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  OKADA KENJI (00396673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 5.  KAGAWA TOSHIKO (40188313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  岩瀬 由未子 (00521882)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  梅村 晋一郎 (20402787)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  弓田 長彦 (40191481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  神野 透人 (10179096)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  須野 学 (20621189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  田中 聡子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 12.  礒部 隆史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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