SONE KENBUN 曾根献文

… Alternative Names

Sone Kenbun 曾根献文

SONE Kembun 曾根献文

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Researcher Number	90598872
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 病院診療医(出向)
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京大学, 医学部附属病院, 准教授 2020 – 2022: 東京大学, 医学部附属病院, 講師 2015 – 2019: 東京大学, 医学部附属病院, 助教 2012: 東京大学, 医学部付属病院, 助教 2011: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 卵巣癌 / 子宮体癌 / PARP阻害剤 / ヒストン修飾 / ChIP-seq / EZH2 / ヒストンメチル化酵素 / 婦人科癌 / DNA修復 / SUV39H 2 … More / 卵巣粘液性癌 / ChIP-seq法 / Hi-C解析 / クロマチン立体構造 / 薬剤耐性 / 深層学習 / 卵巣類内膜癌 / ATAC-seq / 子宮肉腫 / SUV39H2 / エピゲノム / ChIPシークエンス法 / 卵巣明細胞腺癌 / エピゲノム治療薬 / SMYD2 / エピジェネテックス / 卵巣明細胞癌 / CHIP-seq / WHSC1 / ヒストンメチル化 / 実験ロボット / SUV420H1 / ヒストン脱メチル化酵素 / ＥＺＨ２ / 脱メチル化 / メチル化 / エピジェネティクス / 子宮体癌細胞株 / sirtinol / レズベラトロール / 細胞接着能 / 子宮内膜 / E-cadherin / カスパーゼ / アポトーシス / DBC-1 / SIRT1 … More Except Principal Investigator 卵巣癌 / 子宮体癌 / リキッド・バイオプシー / メチル化判定 / 細胞起源 / マルチオミクス解析 / メチル化プロファイル / エピゲノム / RNA結合蛋白 / DNA損傷修復 / PARP阻害剤 / 卵巣がん / 相分離 / DNA損傷修復関連RNA / DNA損傷修復経路 / RNA結合タンパク質 / ヒト内在性レトロウィルス / ヒストン修飾 / 婦人科癌 / PRMT / ERV / ARID1A / 卵巣類内膜癌 / ARID1 / ヒストンメチル化 / Radiogenomics / Radiomics / 人工知能 / ラジオジェノミクス / ラジオミクス / 卵巣腫瘍 / 自動診断 / 深層学習 / 子宮肉腫 Less

Diagnostics of methylation-based predictive biomarkers in ovarian and endometrial carcinomas by using both tumors and liquid biopsy
- Principal Investigator
  
  織田克利
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
DNA損傷関連RNPによる相分離機構の解明と卵巣がん治療への応用
- Principal Investigator
  
  谷川道洋
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokyo Metropolitan Hospital Organization Tokyo Metropolitan Komagome Hospital
Novel therapeutic strategies using histone modifications and DNA repair pathways in refractory gynecological cancerPrincipal Investigator
- Principal Investigator
  
  曾根献文
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Comprehensive Analysis of the Histone Methylation and Endogenous Retrovirus Network in Gynecologic Cancers
- Principal Investigator
  
  Uchino mayuyo
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Radiomics and Radiogenomics Analysis Using Deep Learning in Ovarian Cancer
- Principal Investigator
  
  Miyamoto Yuichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Multimodal analysis of chromatin 3D structure using deep learning in gynecological malignanciesPrincipal Investigator
- Principal Investigator
  
  Sone Kenbun
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Comprehensive analysis and novel epigenomic drug discovery using ChIP sequence in ovarian clear cell adenocarcinoma.Principal Investigator
- Principal Investigator
  
  SONE KENBUN
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
A Project Developing a New Cancer Therapy Targeting Histone Methyltransferase and Demethylase in ovarian cancer and endometrial cancerPrincipal Investigator
- Principal Investigator
  
  Sone Kenbun
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
Development of anti cancer drug targeting longevity related gene -SIRT1 using nanotechnology.Principal Investigator
- Principal Investigator
  
  SONE Kembun
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo

All 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011

All Journal Article Presentation

[Journal Article] Cyclin E1 overexpression sensitizes ovarian cancer cells to WEE1 and PLK1 inhibition2025
- Author(s)
  Xi Q, Kunita A, Ogawa M, Ka M, Tanimoto S, Tsuchimochi S, Nagai S, Matsunaga A, Fukuda T, Watanabe K, Sone K, Shinozaki-Ushiku A, Kawana K, Ushiku T, Osuga Y, Katayama K, Kage H, Oda K.
- Journal Title
  
  Oncogene
  
  Volume: in press Issue: 19 Pages: 1375-1386
- DOI
  10.1038/s41388-025-03312-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02584, KAKENHI-PROJECT-24K14790
[Journal Article] Integrated genomic/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin2024
- Author(s)
  Nishijima A, Oda K, Hasegawa K, Koso T, Asada K, Ikeda Y, Taguchi A, Maeda D, Nagae G, Tsuji S, Tatsuno K, Uehara Y, Kurosaki A, Sato S, Tanikawa M, Sone K, Mori M, Ikemura M, Fujiwara K, Ushiku T, Osuga Y, Aburatani H
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 18797-18797
- DOI
  10.1038/s41598-024-69796-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24H00065, KAKENHI-PROJECT-23K21431, KAKENHI-PROJECT-22K16873, KAKENHI-PROJECT-24K02584, KAKENHI-PROJECT-23K08814
[Journal Article] The automatic diagnosis artificial intelligence system for preoperative magnetic resonance imaging of uterine sarcoma2024
- Author(s)
  Toyohara Yusuke、Sone Kenbun、Noda Katsuhiko、Yoshida Kaname、Kato Shimpei、Kaiume Masafumi、Taguchi Ayumi、Kurokawa Ryo、Osuga Yutaka
- Journal Title
  
  Journal of Gynecologic Oncology
  
  Volume: 35 Issue: 3
- DOI
  10.3802/jgo.2024.35.e24
- Data Source
  KAKENHI-PROJECT-23K08882
[Journal Article] Inhibition of protein arginine methyltransferase 6 activates interferon signaling and induces the apoptosis of endometrial cancer cells via histone modification2024
- Author(s)
  Inoue Futaba、Sone Kenbun、Kumegawa Kohei、Hachijo Ryuta、Suzuki Eri、Tanimoto Saki、Tsuboyama Natsumi、Kato Kosuke、Toyohara Yusuke、Takahashi Yu、Kusakabe Misako、Kukita Asako、Honjoh Harunori、Nishijima Akira、Taguchi Ayumi、Miyamoto Yuichiro、Tanikawa Michihiro、Iriyama Takayuki、Mori Mayuyo　et al
- Journal Title
  
  International Journal of Oncology
  
  Volume: 64 Issue: 3 Pages: 32-32
- DOI
  10.3892/ijo.2024.5620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09591, KAKENHI-PROJECT-21K09489, KAKENHI-PROJECT-21H03074, KAKENHI-PROJECT-22K16873, KAKENHI-PROJECT-23K08814, KAKENHI-PROJECT-23K08882
[Journal Article] BET inhibitor JQ1 induces apoptosis of ovarian and endometrial endometrioid carcinoma cells by down regulating c-Myc2024
- Author(s)
  Tanimoto Saki,Sone Kenbun,Jonouchi Yuri,Hachijo,Ryuta,Suzuki Eri,Tsuboyama Natsumi,Toyohara Yusuke,Inoue Futaba,Honjoh Harunori,Fukuda Tomohiko,Taguchi Ayumi,Miyamoto Yuichiro,Iriyama Takayuki,Mori Mayuyo,Asada Ken,Komatsu Masaaki,Kaneko Syuzo,Hamamoto Ryuji,Wada-Hiraike Osamu,Oda Katsutoshi,Hirota Yasushi,Osuga Yutaka
- Journal Title
  
  Oncology Letters
  
  Volume: 29 Issue: 3 Pages: 106-106
- DOI
  10.3892/ol.2024.14852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09591, KAKENHI-PROJECT-24K02584, KAKENHI-PROJECT-24K03039, KAKENHI-PROJECT-23K08882
[Journal Article] Comorbid thrombosis as an adverse prognostic factor in patients with ovarian clear cell carcinoma regardless of staging2024
- Author(s)
  Yamaguchi Kohei、Tsuruga Tetsushi、Taguchi Ayumi、Tanikawa Michihiro、Sone Kenbun、Mori-Uchino Mayuyo、Iriyama Takayuki、Matsumoto Yoko、Hiraike Osamu、Hirota Yasushi、Fujii Tomoyuki、Osuga Yutaka
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 29 Issue: 9 Pages: 1347-1353
- DOI
  10.1007/s10147-024-02561-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09543, KAKENHI-PROJECT-23K08814, KAKENHI-PROJECT-24K18506
[Journal Article] Evolution of a surgical system using deep learning in minimally invasive surgery (Review)2023
- Author(s)
  Sone Kenbun、Tanimoto Saki、Toyohara Yusuke、Taguchi Ayumi、Miyamoto Yuichiro、Mori Mayuyo、Iriyama Takayuki、Wada-Hiraike Osamu、Osuga Yutaka
- Journal Title
  
  Biomedical Reports
  
  Volume: 19 Issue: 1
- DOI
  10.3892/br.2023.1628
- Data Source
  KAKENHI-PROJECT-21K09466
[Journal Article] Efficacy of regional cooling?+?oral dexamethasone for primary prevention of hand-foot syndrome associated with pegylated liposomal doxorubicin2023
- Author(s)
  Nara Katsuhiko、Taguchi Ayumi、Yamamoto Takehito、Tsuruga Tetsushi、Tojima Yuri、Miyamoto Yuichiro、Tanikawa Michihiro、Sone Kenbun、Mori Mayuyo、Takada Tappei、Suzuki Hiroshi、Osuga Yutaka
- Journal Title
  
  Supportive Care in Cancer
  
  Volume: 31 Issue: 5
- DOI
  10.1007/s00520-023-07718-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08814
[Journal Article] Effect of pelvic radiotherapy on patients with stage IB-IIA cervical cancer after radical hysterectomy: A single center retrospective study.2023
- Author(s)
  Ishizawa C, Taguchi A, Tanikawa M, Honjo H, Nishijima A, Eguchi S, Miyamoto Y, Sone K, Tsuruga T, Mori M, Osuga Y.
- Journal Title
  
  Oncol Lett.
  
  Volume: 25 Issue: 3 Pages: 112-112
- DOI
  10.3892/ol.2023.13698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18157, KAKENHI-PROJECT-23K08814
[Journal Article] Heterogeneous effects of cytotoxic chemotherapies for platinum-resistant ovarian cancer2023
- Author(s)
  Nara Katsuhiko、Taguchi Ayumi、Yamamoto Takehito、Hara Konan、Tojima Yuri、Honjoh Harunori、Nishijima Akira、Eguchi Satoko、Miyamoto Yuichiro、Sone Kenbun、Mori Mayuyo、Takada Tappei、Osuga Yutaka
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 28 Issue: 9 Pages: 1207-1217
- DOI
  10.1007/s10147-023-02367-1
- Data Source
  KAKENHI-PROJECT-21K09466
[Journal Article] Heterogeneous treatment effects of adjuvant therapy for patients with cervical cancer in the intermediate‐risk group2023
- Author(s)
  Taguchi Ayumi、Kato Kosuke、Hara Konan、Furusawa Akiko、Nakajima Yujiro、Ishizawa Chihiro、Tanikawa Michihiro、Sone Kenbun、Mori Mayuyo、Shimada Muneaki、Okamoto Aikou、Takekuma Munetaka
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 18 Pages: 18557-18567
- DOI
  10.1002/cam4.6460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08814
[Journal Article] Identification of target cells of human papillomavirus 18 using squamocolumnar junction organoids2023
- Author(s)
  Toyohara Yusuke、Taguchi Ayumi、Ishii Yoshiyuki、Yoshimoto Daisuke、Yamazaki Miki、Matsunaga Hiroko、Nakatani Kazuma、Hoshi Daisuke、Tsuchimochi Saki、Kusakabe Misako、Baba Satoshi、Kawata Akira、Ikemura Masako、Tanikawa Michihiro、Sone Kenbun et al
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 1 Pages: 125-138
- DOI
  10.1111/cas.15988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08882, KAKENHI-PROJECT-22K16853, KAKENHI-PROJECT-21H03074, KAKENHI-PROJECT-23K08814
[Journal Article] A case of refractory pelvic squamous cell carcinoma of unknown primary that responded to nivolumab.2023
- Author(s)
  Komura A, Taguchi A, Ikemura M, Nishijima A, Miyamoto Y, Tanikawa M, Sone K, Mori M, Oda K, Osuga Y.
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 49 Issue: 4 Pages: 1300-1304
- DOI
  10.1111/jog.15548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18157, KAKENHI-PROJECT-23K08814
[Journal Article] Characterization of a fluorescence imaging probe that exploits metabolic dependency of ovarian clear cell carcinoma2023
- Author(s)
  Tsuchimochi Saki、Wada-Hiraike Osamu、Urano Yasuteru、Kukita Asako、Yamaguchi Kohei、Honjo Harunori、Taguchi Ayumi、Tanikawa Michihiro、Sone Kenbun、Mori-Uchino Mayuyo、Tsuruga Tetsushi、Oda Katsutoshi、Osuga Yutaka
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 20292-20292
- DOI
  10.1038/s41598-023-47637-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09543, KAKENHI-PROJECT-23K08814, KAKENHI-PROJECT-21K09489, KAKENHI-PROJECT-21H03074
[Journal Article] Transiently elevated D‐dimer levels post‐concentrated ascites reinfusion therapy cannot be used to predict deep vein thrombosis‐pulmonary embolism2022
- Author(s)
  Sone Kenbun、Taguchi Ayumi、Kawata Akira、Eguchi Satoko、Miyamoto Yuichiro、Tanikawa Michihiro、Uchino‐Mori Mayuyo、Iriyama Takayuki、Tsuruga Tetsushi、Osuga Yutaka
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 48 Issue: 3 Pages: 817-823
- DOI
  10.1111/jog.15162
- Data Source
  KAKENHI-PROJECT-20H03820
[Journal Article] The Histone Methyltransferase SETD8 Regulates the Expression of Tumor Suppressor Genes via H4K20 Methylation and the p53 Signaling Pathway in Endometrial Cancer Cells2022
- Author(s)
  Kukita Asako、Sone Kenbun、Wada-Hiraike Osamu (21)、Oda Katsutoshi、Hamamoto Ryuji、Osuga Yutaka
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 21 Pages: 5367-5367
- DOI
  10.3390/cancers14215367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09489, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-21H03074
[Journal Article] Histone arginine methyltransferase CARM1 selective inhibitor TP-064 induces apoptosis in endometrial cancer2022
- Author(s)
  Inoue Futaba、Sone Kenbun、Toyohara Yusuke、Tanimoto Saki、Takahashi Yu、Kusakabe Misako、Kukita Asako、Honjoh Harunori、Nishijima Akira、Taguchi Ayumi、Miyamoto Yuichiro、Tanikawa Michihiro、Iriyama Takayuki、Uchino Mayuyo-mori、Tsuruga Tetsushi、Wada-Hiraike Osamu、Oda Katsutoshi、Osuga Yutaka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 601 Pages: 123-128
- DOI
  10.1016/j.bbrc.2022.02.086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20K09662, KAKENHI-PROJECT-21K09489, KAKENHI-PROJECT-22K09543, KAKENHI-PROJECT-20H03820
[Journal Article] Genetic diagnosis of pseudomyxoma peritonei originating from mucinous borderline tumor inside an ovarian teratoma2022
- Author(s)
  Taguchi Ayumi、Rokutan Hirofumi、Oda Katsutoshi、Tanikawa Michihiro、Tanimoto Saki、Sone Kenbun、Mori Mayuyo、Tsuruga Tetsushi、Kohsaka Shinji、Tatsuno Kenji、Shinozaki-Ushiku Aya、Miyagawa Kiyoshi、Mano Hiroyuki、Aburatani Hiroyuki、Ushiku Tetsuo、Osuga Yutaka
- Journal Title
  
  BMC Medical Genomics
  
  Volume: 15 Issue: 1 Pages: 51-51
- DOI
  10.1186/s12920-022-01188-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-20K09662, KAKENHI-PROJECT-21H03074
[Journal Article] MED1, a novel binding partner of BRCA1, regulates homologous recombination and R-loop processing2022
- Author(s)
  Honjoh Harunori、Tanikawa Michihiro、Wada-Hiraike Osamu、Oda Katsutoshi、Inaba Hirofumi、Kukita Asako、Kawata Yoshiko、Kusakabe Misako、Tsuchimochi Saki、Taguchi Ayumi、Miyamoto Yuichiro、Sone Kenbun、Tsuruga Tetsushi、Mori-Uchino Mayuyo、Matsumoto Yoko、Osuga Yutaka
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 17140-17140
- DOI
  10.1038/s41598-022-21495-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09489, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-20K09662, KAKENHI-PROJECT-21K09465, KAKENHI-PROJECT-21H03074
[Journal Article] Recurrent malignant melanoma of the uterine cervix treated with anti-PD-1 antibodies and anti-CTLA-4 antibodies: A case report2022
- Author(s)
  Sone Kenbun、Kukita Asako、Masui Yuri、Yamada Daisuke、Shinozaki-Ushiku Aya、Kawata Akira、Taguchi Ayumi、Miyamoto Yuichiro、Tanikawa Michihiro、Iriyama Takayuki、Mori-Uchino Mayuyo、Tsuruga Tetsushi、Osuga Yutaka
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 16 Issue: 3 Pages: 1-6
- DOI
  10.3892/mco.2022.2496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18157, KAKENHI-PROJECT-20H03820
[Journal Article] The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma2022
- Author(s)
  Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Noriko Ikawa, Ken Asada, Ryuichiro Nakato, Kanto Shozu, Ai Dozen, Kenbun Sone, Hiroshi Yoshida, Tomoyasu Kato, Katsutoshi Oda, Yutaka Osuga, Tomoyuki Fujii, Gottfried von Keudell, Vassiliki Saloura, Ryuji Hamamoto
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 39-39
- DOI
  10.1038/s42003-021-02992-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-21H03074
[Journal Article] Suspicious Positive Peritoneal Cytology (Class III) in Endometrial Cancer Does Not Affect Prognosis2022
- Author(s)
  Sone Kenbun、Suzuki Eri、Taguchi Ayumi、Honjoh Harunori、Nishijima Akira、Eguchi Satoko、Miyamoto Yuichiro、Iriyama Takayuki、Mori Mayuyo、Osuga Yutaka
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 21 Pages: 6527-6527
- DOI
  10.3390/jcm11216527
- Data Source
  KAKENHI-PROJECT-22K09591, KAKENHI-PROJECT-20H03820
[Journal Article] Development of a deep learning method for improving diagnostic accuracy for uterine sarcoma cases2022
- Author(s)
  Toyohara Yusuke、Sone Kenbun、Noda Katsuhiko、Yoshida Kaname、Kurokawa Ryo、Tanishima Tomoya、Kato Shimpei、Inui Shohei、Nakai Yudai、Ishida Masanori、Gonoi Wataru、Tanimoto Saki、Takahashi Yu、Inoue Futaba、Kukita Asako、Kawata Yoshiko、Taguchi Ayumi、Furusawa Akiko、Miyamoto Yuichiro et al
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 19612-19612
- DOI
  10.1038/s41598-022-23064-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21H03074
[Journal Article] A low preoperative albumin-to-globulin ratio is a negative prognostic factor in patients with surgically treated cervical cancer2021
- Author(s)
  Kawata Akira、Taguchi Ayumi、Baba Satoshi、Miyamoto Yuichiro、Tanikawa Michihiro、Sone Kenbun、Tsuruga Tetsushi、Mori Mayuyo、Oda Katsutoshi、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 5 Pages: 980-985
- DOI
  10.1007/s10147-021-01861-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09662, KAKENHI-PROJECT-18K09303, KAKENHI-PROJECT-19K07636, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21K09553
[Journal Article] Elevated placental histone H3K4 methylation via upregulated histone methyltransferases SETD1A and SMYD3 in preeclampsia and its possible involvement in hypoxia-induced pathophysiological process.2021
- Author(s)
  H. Matsui, T. Iriyama, S. Sayama, N. Inaoka, K. Suzuki, M. Yoshikawa, M. Ichinose, K. Sone, K. Kumasawa, T. Nagamatsu, T. Fujisawa, I. Naguro, H. Ichijo, T. Fujii, Y. Osuga
- Journal Title
  
  Placenta
  
  Volume: 115 Pages: 60-69
- DOI
  10.1016/j.placenta.2021.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15358, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-20K18158
[Journal Article] Enhanced antitumor activity of combined lipid bubble ultrasound and anticancer drugs in gynecological cervical cancers2021
- Author(s)
  Yamaguchi Kohei、Matsumoto Yoko、Suzuki Ryo、Nishida Haruka、Omata Daiki、Inaba Hirofumi、Kukita Asako、Tanikawa Michihiro、Sone Kenbun、Oda Katsutoshi、Osuga Yutaka、Maruyama Kazuo、Fujii Tomoyuki
- Journal Title
  
  Cancer Science
  
  Volume: on line Issue: 6 Pages: 1-11
- DOI
  10.1111/cas.14907
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09662, KAKENHI-PROJECT-18K16791, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-20H04519, KAKENHI-PROJECT-21K09465, KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-21H03074
[Journal Article] History of whole pelvis plus para-aortic radiation is a risk factor associated with febrile neutropenia during chemotherapy for recurrent cervical cancer2021
- Author(s)
  Nara Katsuhiko、Taguchi Ayumi、Tojima Yuri、Miyamoto Yuichiro、Tanikawa Michihiro、Sone Kenbun、Mori Mayuyo、Tsuruga Tetsushi、Yamamoto Takehito、Takenaka Ryosuke、Takada Tappei、Osuga Yutaka、Suzuki Hiroshi
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 9 Pages: 1759-1766
- DOI
  10.1007/s10147-021-01950-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07636, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-20K07127, KAKENHI-PROJECT-20K18157
[Journal Article] Intraperitoneal Administration of a Cisplatin-Loaded Nanogel through a Hybrid System Containing an Alginic Acid-Based Nanogel and an <i>In Situ</i> Cross-Linkable Hydrogel for Peritoneal Dissemination of Ovarian Cancer2021
- Author(s)
  Yamaguchi Kohei、Hiraike Osamu、Iwaki Haruna、Matsumiya Kazuki、Nakamura Noriko、Sone Kenbun、Ohta Seiichi、Osuga Yutaka、Ito Taichi
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 18 Issue: 11 Pages: 4090-4098
- DOI
  10.1021/acs.molpharmaceut.1c00514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21101, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-21K09489
[Journal Article] Application of artificial intelligence in gynecologic malignancies: A review2021
- Author(s)
  Sone Kenbun、Toyohara Yusuke、Taguchi Ayumi、Miyamoto Yuichiro、Tanikawa Michihiro、Uchino‐Mori Mayuyo、Iriyama Takayuki、Tsuruga Tetsushi、Osuga Yutaka
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 47 Issue: 8 Pages: 2577-2585
- DOI
  10.1111/jog.14818
- Data Source
  KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21K09466
[Journal Article] Genome-Wide Chromatin Analysis of FFPE Tissues Using a Dual-Arm Robot with Clinical Potential2021
- Author(s)
  Kaneko S、Mitsuyama T、Shiraishi K、Ikawa N、Shozu K、Dozen A、Machino H、Asada K、Komatsu M、Kukita A、Sone K、Yoshida H、Motoi N、Hayami S、Yoneoka Y、Kato T、Kohno T、Natsume T、Keudell GV、Saloura V、Yamaue H、Hamamoto R
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 9 Pages: 2126-2126
- DOI
  10.3390/cancers13092126
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-20H03820
[Journal Article] Desensitization strategy for hypersensitivity reactions to carboplatin in five patients with gynecological cancer2020
- Author(s)
  Toyohara Yusuke、Sone Kenbun、Nishida Haruka、Taguchi Ayumi、Miyamoto Yuichiro、Tanikawa Michihiro、Mori Mayuyo、Tsuruga Tetsushi、Matsumoto Yoko、Oda Katsutoshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 46 Issue: 11 Pages: 2298-2304
- DOI
  10.1111/jog.14443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-18K09249
[Journal Article] Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer2020
- Author(s)
  Wada Miku、Kukita Asako、Sone Kenbun、Hamamoto Ryuji、Kaneko Syuzo、Komatsu Masaaki、Takahashi Yu、Inoue Futaba、Kojima Machiko、Honjoh Harunori、Taguchi Ayumi、Kashiyama Tomoko、Miyamoto Yuichiro、Tanikawa Michihiro、Tsuruga Tetsushi、Mori-Uchino Mayuyo、Wada-Hiraike Osamu、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 12 Pages: 1686-1686
- DOI
  10.3390/biom10121686
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K11542
[Journal Article] Effect of murine double‐minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys2020
- Author(s)
  Kawata Yoshiko、Nagasaka Kazunori、Oda Katsutoshi、Makii Chinami、Takeuchi Makoto、Oki Shinya、Honjo Harunori、Kojima Machiko、Miyagawa Yuko、Taguchi Ayumi、Tanikawa Michihiro、Sone Kenbun、Hiraike Haruko、Matsumoto Yoko、Wada‐Hiraike Osamu、Ayabe Takuya、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 10 Pages: 3824-3834
- DOI
  10.1111/cas.14583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09834, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K09249
[Journal Article] The histone methyltransferase SMYD2 is a novel therapeutic target for the induction of apoptosis in ovarian clear cell carcinoma cells2020
- Author(s)
  Kojima Machiko、Sone Kenbun、Oda Katsutoshi、Hamamoto Ryuji、Kaneko Syuzo、Oki Shinya、Kukita Asako、Kawata Akira、Honjoh Harunori、Kawata Yoshiko、Kashiyama Tomoko、Sato Masakazu、Taguchi Ayumi、Miyamoto Yuichiro、Tanikawa Michihiro、Tsuruga Tetsushi、Nagasaka Kazunori、Wada?Hiraike Osamu、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Oncology Letters
  
  Volume: 20 Issue: 5 Pages: 1-1
- DOI
  10.3892/ol.2020.12014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-18K11542
[Journal Article] Usefulness of biopsy by office hysteroscopy for endometrial cancer: A case report2020
- Author(s)
  Sone Kenbun、Eguchi Satoko、Asada Kayo、Inoue Futaba、Miyamoto Yuichiro、Tanikawa Michihiro、Tsuruga Tetsushi、Mori?Uchino Mayuyo、Matsumoto Yoko、Hiraike?Wada Osamu、Oda Katsutoshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 13 Issue: 2 Pages: 141-145
- DOI
  10.3892/mco.2020.2053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15304, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-18K09249
[Journal Article] Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma2019
- Author(s)
  Makii Chinami、Ikeda Yuji、Oda Katsutoshi、Wada-Hiraike Osamu、Kawana Kei、Hasegawa Kosei、Fujiwara Keiichi、Aburatani Hiroyuki、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Gynecologic Oncology
  
  Volume: 155 Issue: 2 Pages: 331-339
- DOI
  10.1016/j.ygyno.2019.08.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-17K11268
[Journal Article] The histone methyltransferase WHSC1 is regulated by EZH2 and is important for ovarian clear cell carcinoma cell proliferation2019
- Author(s)
  Kojima Machiko、Sone Kenbun、Wada-Hiraike Osamu、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  BMC Cancer
  
  Volume: 19 Issue: 1 Pages: 455-455
- DOI
  10.1186/s12885-019-5638-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-18K15304, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-18K16759
[Journal Article] Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary2019
- Author(s)
  Akino Nana、Wada-Hiraike Osamu、Isono Wataru、Terao Hiromi、Honjo Harunori、Miyamoto Yuichiro、Tanikawa Michihiro、Sone Kenbun、Hirano Mana、Harada Miyuki、Hirata Tetsuya、Hirota Yasushi、Koga Kaori、Oda Katsutoshi、Fujii Tomoyuki、Osuga Yutaka
- Journal Title
  
  Reproductive Biology and Endocrinology
  
  Volume: 17 Issue: 1 Pages: 2323-2323
- DOI
  10.1186/s12958-019-0466-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-18K19600, KAKENHI-PROJECT-18K19601, KAKENHI-PROJECT-17J02723, KAKENHI-PROJECT-18K16759, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-19H03144
[Journal Article] Interleukin-17 is associated with expression of programmed cell death 1 ligand 1 in ovarian carcinoma.2019
- Author(s)
  Aotsuka A, Matsumoto Y, Arimoto T, Kawata A, Ogishima J, Taguchi A, Tanikawa M, Sone K, Mori-Uchino M, Tsuruga T, Oda K, Kawana K, Osuga Y, Fujii T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110 Issue: 10 Pages: 3068-3078
- DOI
  10.1111/cas.14174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-17K11269, KAKENHI-PROJECT-18K16757, KAKENHI-PROJECT-18K16759
[Journal Article] Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas.2019
- Author(s)
  Kukita A, Sone K, Oda K, Hamamoto R, Kaneko S, Komatsu M, Wada M, Honjoh H, Kawata Y, Kojima M, Oki S, Sato M, Asada K, Taguchi A, Miyasaka A, Tanikawa M, Nagasaka K, Matsumoto Y, Wada-Hiraike O, Osuga Y, Fujii T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: in press Issue: 2 Pages: 30555-8
- DOI
  10.1016/j.bbrc.2019.03.155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-16K21330, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-18K15304, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-18K16757, KAKENHI-PROJECT-18K16759
[Journal Article] Anti-Tumor Effect of Inhibition of DNA Damage Response Proteins, ATM and ATR, in Endometrial Cancer Cells2019
- Author(s)
  Takeuchi Makoto、Tanikawa Michihiro、Nagasaka Kazunori、Oda Katsutoshi、Kawata Yoshiko、Oki Shinya、Agapiti Chuwa、Sone Kenbun、Miyagawa Yuko、Hiraike Haruko、Wada-Hiraike Osamu、Kuramoto Hiroyuki、Ayabe Takuya、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Cancers
  
  Volume: 11 Issue: 12 Pages: 1913-1913
- DOI
  10.3390/cancers11121913
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-19K09834, KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-18K16759, KAKENHI-PROJECT-16H05469
[Journal Article] Usefulness of cell-free and concentrated ascites reinfusion therapy in the therapeutic management of advanced ovarian cancer patients with massive ascites2018
- Author(s)
  Kawata Yoshiko、Nagasaka Kazunori、Matsumoto Yoko、Oda Katsutoshi、Tanikawa Michihiro、Sone Kenbun、Mori-Uchino Mayuyo、Tsuruga Tetsushi、Arimoto Takahide、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 24 Issue: 4 Pages: 420-427
- DOI
  10.1007/s10147-018-1371-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-18K09249
[Journal Article] Kaempferol, a natural dietary flavonoid, suppresses 17β?estradiol?induced survivin expression and causes apoptotic cell death in endometrial cancer2018
- Author(s)
  Chuwa Agapiti、Sone Kenbun、Oda Katsutoshi、Tanikawa Michihiro、Kukita Asako、Kojima Machiko、Oki Shinya、Fukuda Tomohiko、Takeuchi Makoto、Miyasaka Aki、Kashiyama Tomoko、Ikeda Yuji、Nagasaka Kazunori、Mori?Uchino Mayuyo、Matsumoto Yoko、Wada?Hiraike Osamu、Kuramoto Hiroyuki、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Oncology Letters
  
  Volume: 16 Pages: 6195-6201
- DOI
  10.3892/ol.2018.9340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-16K21330, KAKENHI-PROJECT-17K16832
[Journal Article] Oncogenic histone methyltransferase EZH2: A novel prognostic marker with therapeutic potential in endometrial cancer.2017
- Author(s)
  Oki S, Sone K, Oda K, Hamamoto R, Ikemura M, Maeda D, Takeuchi M, Tanikawa M, Mori-Uchino M, Nagasaka K, Miyasaka A, Kashiyama T, Ikeda Y, Arimoto T, Kuramoto H, Wada-Hiraike O, Kawana K, Fukayama M, Osuga Y, Fujii T.
- Journal Title
  
  Oncotarget
  
  Volume: in press Issue: 25 Pages: 40402-40411
- DOI
  10.18632/oncotarget.16316
- NAID
  120007089062
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-15K20128, KAKENHI-PROJECT-16K20176, KAKENHI-PROJECT-16K08646, KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-15K10705
[Journal Article] Recent advances in targeting DNA repair pathways for the treatment of ovarian cancer and their clinical relevance2017
- Author(s)
  Oda Katsutoshi、Tanikawa Michihiro、Sone Kenbun、Mori-Uchino Mayuyo、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 22 Issue: 4 Pages: 611-618
- DOI
  10.1007/s10147-017-1137-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11268, KAKENHI-PROJECT-16H06757, KAKENHI-PROJECT-16K20176
[Journal Article] Prognostic importance of CDK4/6-specific activity as a predictive marker for recurrence in patients with endometrial cancer, with or without adjuvant chemotherapy.2015
- Author(s)
  keda Y, Oda K, Ishihara H, Wada-Hiraike O, Miyasaka A, Kashiyama T, Inaba K, Fukuda T, Sone K, Matsumoto Y, Arimoto T, Maeda D, Ikemura M, Fukayama M, Kawana K, Yano T, Aoki D, Osuga Y, Fujii T.
- Journal Title
  
  Br J Cancer
  
  Volume: 113 Issue: 10 Pages: 1477-1483
- DOI
  10.1038/bjc.2015.369
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-15K20128, KAKENHI-PROJECT-25861471, KAKENHI-PROJECT-26870129
[Journal Article] SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells2015
- Author(s)
  Theodore Vougiouklakis,,Kenbun Sone, Vassiliki Saloura, Hyun-Soo Cho, Takehiro Suzuki, Naoshi Dohmae, Houda Alachkar, Yusuke Nakamura, Ryuji Hamamoto
- Journal Title
  
  Oncotarget
  
  Volume: 41 Issue: 41 Pages: 43162-71
- DOI
  10.18632/oncotarget.6351
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20128
[Journal Article] Antitumor activity of a combination of dual PI3K/mTOR inhibitor SAR245409 and selective MEK1/2 inhibitor pimasertib in endometrial carcinomas.2015
- Author(s)
  Inaba K, Oda K, Ikeda Y, Sone K, Miyasaka A, Kashiyama T, Fukuda T, Uehara Y, Arimoto T, Kuramoto H, Wada-Hiraike O, Kawana K, Yano T, Osuga Y, Fujii T.
- Journal Title
  
  Gynecol Oncol
  
  Volume: 138 Issue: 2 Pages: 323-331
- DOI
  10.1016/j.ygyno.2015.05.031
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-15K20128, KAKENHI-PROJECT-25861471
[Journal Article] PI3K/mTOR pathway inhibition overcomes radioresistance via suppression of the HIF1-α/VEGF pathway in endometrial cancer.2015
- Author(s)
  Miyasaka A, Oda K, Ikeda Y, Sone K, Fukuda T, Inaba K, Makii C, Enomoto A, Hosoya N, Tanikawa M, Uehara Y, Arimoto T, Kuramoto H, Wada-Hiraike O, Miyagawa K, Yano T, Kawana K, Osuga Y, Fujii T.
- Journal Title
  
  Gynecol Oncol
  
  Volume: 138 Issue: 1 Pages: 174-180
- DOI
  10.1016/j.ygyno.2015.04.015
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-15K20128, KAKENHI-PROJECT-25861471
[Journal Article] The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition.2015
- Author(s)
  Fukuda T, Oda K, Wada-Hiraike O, Sone K, Inaba K, Ikeda Y, Miyasaka A, Kashiyama T, Tanikawa M, Arimoto T, Kuramoto H, Yano T, Kawana K, Osuga Y, Fujii T.
- Journal Title
  
  Gynecol Oncol
  
  Volume: 137 Issue: 3 Pages: 538-545
- DOI
  10.1016/j.ygyno.2015.03.053
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10704, KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-15K20128
[Journal Article] Sequential effects of the proteasome inhibitor bortezomib and chemotherapeutic agents in uterine cervical cancer cell lines.2013
- Author(s)
  Miyamoto Y, Nakagawa S, Wada-Hiraike O, Seiki T, Tanikawa M, Hiraike H, Sone K, Nagasaka K, Oda K, Kawana K, Nakagawa K, Fujii T, Yano T, Kozuma S, Taketani Y.
- Journal Title
  
  Oncol Rep.
  
  Volume: 29(1) Issue: 1 Pages: 51-7
- DOI
  10.3892/or.2012.2072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591848, KAKENHI-PROJECT-23390298, KAKENHI-PROJECT-23390308, KAKENHI-PROJECT-23592436, KAKENHI-PROJECT-23592437, KAKENHI-PROJECT-24592505, KAKENHI-PROJECT-24592506, KAKENHI-PROJECT-23791811
[Journal Article] Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells : an implicative role of SIRT1 in the ovary2012
- Author(s)
  Y.Morita, K.Tsutsui, et al
- Journal Title
  
  Reprod.Biol.Endocrinbl.
  
  Volume: (in press) Issue: 1 Pages: 14-24
- DOI
  10.1186/1477-7827-10-14
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-22591848, KAKENHI-PROJECT-23592437, KAKENHI-PROJECT-23791811
[Journal Article] Resveratrol promotes expression on SIRT1 And StAR in rad ovarian granulosa cells2012
- Author(s)
  Morita Y,Wada-Hiraike O,Yano T,Shirane A,Hirano M,Hiraike H,Koyama S,Oisihi H, Yoshino O,Miyamoto Y,Sone K,Oda K, Nakagawa S,Tsutsui k,Taketani Y
- Journal Title
  
  an Implicative role of SIRT1 in the ovary Reproductive Biology and endocrinology
  
  Volume: 10 Pages: 14-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791811
[Journal Article] Regulation of SIRT1 determines initial step of endometrial receptivity by controlling E-cadherin expression2012
- Author(s)
  Shirane A, Wada-Hiraike O, Tanikawa M, Seiki T, Hiraike H, Miyamoto Y, Sone K, Hirano M, Oishi H, Oda K, Kawana K, Nakagawa S, Osuga Y, Fujii T, Yano T, Kozuma S, Taketani Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 424 Issue: 3 Pages: 604-10
- DOI
  10.1016/j.bbrc.2012.06.160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592436, KAKENHI-PROJECT-24592505, KAKENHI-PROJECT-23791811
[Journal Article] Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas.2012
- Author(s)
  Shoji K, Oda K, Nakagawa S,-Hiraike O, McCormick F, Aburatani H, Yano T, Kozuma S, Taketani Y.
- Journal Title
  
  PLoS One
  
  Volume: 7(5): Issue: 5 Pages: e37431-e37431
- DOI
  10.1371/journal.pone.0037431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591848, KAKENHI-PROJECT-23592436, KAKENHI-PROJECT-23592437, KAKENHI-PROJECT-23791812, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-23791811
[Journal Article] equential effects of the proteasome inhibitor bortezomib and chemotherapeutic agents in uterine cervical cancer cell lines2012
- Author(s)
  Miyamoto Y, Nakagawa S, Wada-Hiraike O, Seiki T, Tanikawa M, Hiraike H, Sone K, Nagasaka K, Oda K, Kawana K, Nakagawa K, Fujii T, Yano T, Kozuma S, Taketani Y.
- Journal Title
  
  Oncology Reports
  
  Volume: 29 Pages: 51-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791811
[Journal Article] Multifunctional transpription factor TF II?1 is an activator of BRACA1 function2011
- Author(s)
  Tanikawa M,Wada-Hiraike O,Nakagawa S, Shirane A,Hiraike H,Koyama S,Miyamoto Y Sone K,Tsuruga T,Nagasaka K,Matsumoto Y, Ikeda Y,Shoji K,Oda K,Fukuhara H,Nakagawa K,Kato S,Yano T,Taketani Y
- Journal Title
  
  British journal of cancer
  
  Volume: 104 Pages: 1349-1355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791811
[Journal Article] Multifunctional transcription factor TFII-I is an activator of BRCA1 function2011
- Author(s)
  Tanikawa M, Wada Hiraike O, Nakagawa S, Shirane A, Hiraike H, Koyama S, Miyamoto Y, Sone K, Tsuruga T, Nagasaka K, Matsumoto Y, Ikeda Y, Shoji K, Oda K, et al
- Journal Title
  
  Br J Cancer
  
  Volume: 104 Issue: 8 Pages: 1349-1355
- DOI
  10.1038/bjc.2011.75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592437, KAKENHI-PROJECT-23791811
[Presentation] 卵巣がん細胞におけるサイクリンE1の過剰発現はWEE1阻害薬の効果予測バイオマーカーとなり得る.2024
- Author(s)
  Xi Qian、鹿毛秀宣、小川弥穂、国田朱子、何美玲、松永麻美、渡邊広祐、曾根献文、川名敬、大須賀穣、織田克利.
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-24K02584
[Presentation] Genomic landscape of gynecologic cancers with poor prognosis in Japan, an analysis of the national database of comprehensive genomic profiling tests2024
- Author(s)
  Qian Xi; Hidenori Kage; Miho Ogawa; Asami Matsunaga; Akira Nishijima; Kenbun Sone; Kei Kawana; Katsutoshi Oda
- Organizer
  AACR Annual Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02584
[Presentation] 婦人科がんゲノム診断・治療のnext innovation：フラグメント解析を用いたBRCA1メチル化検査法の確立と臨床応用.2024
- Author(s)
  土持早希、田口歩、山本陽子、河津正人、良元大介、深谷小百合、石坂彩、宮本雄一郎、曾根献文、森繭代、平池修、織田克利、廣田泰、大須賀穣.
- Organizer
  第66回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-24K02584
[Presentation] ChIP-シークエンス（ChIP-seq）法を用いた婦人科がんにおけるヒストン修飾が及ぼす癌化メカニズムの解明とエピゲノム標的治療薬の探索について2019
- Author(s)
  曾根　献文
- Organizer
  第71回日本産科婦人科学会学術講演会　シンポジウム
- Data Source
  KAKENHI-PROJECT-17K11268
[Presentation] ChIP-シークエンス（ChIP-seq）法を用いた婦人科がんにおけるヒストン修飾が及ぼす癌化メカニズムの解明とエピゲノム標的治療薬の探索について2019
- Author(s)
  曾根献文
- Organizer
  第71回日本産婦人科学会学術総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K11268
[Presentation] ヒストンメチル化酵素SETD8を標的とした子宮体癌における新規エピゲノム創薬の検討2017
- Author(s)
  大木慎也　曾根献文　織田克利　町野英徳　児嶋真千子　川田淑子　 Chuwa Agapiti　福田友彦　宮坂亞希　谷川道洋　長阪一憲　松本陽子　平池修　大須賀穣　藤井知行
- Organizer
  第 59 回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K11268
[Presentation] Oncogenic histone methyltransferase EZH2: A novel prognostic marker and therapeutic target in endometrial cancer2017
- Author(s)
  Oki Shinya, Sone Kenbun, Oda Katsutoshi, Tanikawa Michihiro, Nagasaka Kazunori, Ikeda Yuji, Arimoto Takahide, Kuramoto Hiroyuki, Hiraike Osamu, Kawana Kei, Osuga Yutaka, Fujii Tomoyuk
- Organizer
  第69回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K11268
[Presentation] The histone methyltransferase EZH2 is a novel target of anti-cancer therapy in endometrial cancer.2016
- Author(s)
  Shinya Oki, Kenbun Sone, Katsutoshi Oda, Akira Nishijima, Makoto Takeuchi, Agapiti Chuwa, Kayo Asada, Chinami Makii, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  2016 AACR annual meeting
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20128
[Presentation] The histone methyltransferase, SUV39H2, is a potent target of anticancer therapy in endometrial cancer2016
- Author(s)
  Kenbun Sone, Katsutoshi Oda, Shinya Oki, Makoto Takeuchi, Agapiti Hipoliti Chuwa ,Chinami Makii, Tomoko Kashiyama, Yuji Ikeda, Osamu Wada-Hiraike, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K20128
[Presentation] The histone methyltransferase EZH2 is a novel target of anti-cancer therapy in endometrial cancer2016
- Author(s)
  Shinya Oki, Kenbun Sone, Katsutoshi Oda, Akira Nishijima, Makoto Takeuchi, Agapiti Chuwa, Kayo Asada, Chinami Makii,Kei Kawana, Yutaka Osuga, Tomoyuki Fujii,
- Organizer
  AACR annual meeting
- Place of Presentation
  ニューオーリンズ
- Year and Date
  2016-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20128
[Presentation] Histone methyl/demthyltrasnferases are novel targets of anti-cancer therapy in endometrial cancer.2016
- Author(s)
  Shinya Oki, Kenbun Sone, Katsutoshi Oda, Chinami Makii, Kayo Asada, Agapiti Chuwa, Makoto Takeuchi, Osamu Hiraike-Wada, Hiroyuki Kuramoto, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  日本産婦人科学会学術総会
- Place of Presentation
  東京
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-15K20128
[Presentation] 当科での子宮内膜異型増殖症、高分化子宮体癌に対するMPA療法を用いた妊孕性温存治療に関する検討2012
- Author(s)
  宮本雄一郎、佐藤英貴、三浦紫保、長阪一憲、曾根献文, 松本陽子, 有本貴英, 織田克利, 川名敬, 矢野哲, 上妻志郎, 武谷雄二
- Organizer
  日本婦人科腫瘍学会
- Place of Presentation
  新高輪プリンスホテル
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-23791811
[Presentation] 子宮体癌リンパ節転移陽性(臨床進行期IIIc)例における予後因子の検討2012
- Author(s)
  園田正樹、織田克利,有本貴英,武家尾舞子,曾根献文,森繭代,松本陽子,川名敬,中川俊介,矢野哲,上妻志郎,武谷雄二
- Organizer
  日本婦人科腫瘍学会
- Place of Presentation
  新高輪プリンスホテル
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-23791811
[Presentation] 胚細胞性腫瘍に対するBEP療法の有害事象と妊孕性に関する検討2011
- Author(s)
  曾根献文、有本貴英、川名敬、塚崎雄大、松本陽子、土谷聡、西田晴香、織田克利、中川俊介、上妻志郎、武谷雄二
- Organizer
  日本婦人科腫瘍学会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23791811
[Presentation] 再発卵巣癌に対するsalvage chemotherapy としてのweekly CPT-11療法の有用性の検討2011
- Author(s)
  曾根献文、松本陽子、森繭代、有本貴英、織田克利、川名敬、中川俊介、上妻志郎、武谷雄二
- Organizer
  日本癌治療学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791811
[Presentation] 当科での子宮内膜異型増殖症、高分化子宮体癌に対するMPA療法を用いた妊孕性温存治療に関する検討胚細胞性腫瘍に対するBEP療法の有害事象と妊孕性に関する検討2011
- Author(s)
  宮本雄一郎、佐藤英貴,三浦紫保,長阪一憲,曾根献文,松本陽子,有本貴英,織田克利,川名敬,矢野哲,上妻志郎,武谷雄二
- Organizer
  日本婦人科腫瘍学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-23791811
[Presentation] 再発卵巣癌に対するsalvage chemotherapy2011
- Author(s)
  曾根献文、松本陽子、森繭代、有本貴英、
- Organizer
  日本癌治療学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-23791811
[Presentation] 胚細胞性腫瘍に対するBEP療法の有害事象2011
- Author(s)
  曾根献文、有本貴英、川名敬、塚崎雄大、
- Organizer
  日本婦人科腫瘍学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-23791811

1. 田口歩 (60756782)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. Miyamoto Yuichiro (70634955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. Uchino mayuyo (30570452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 谷川道洋 (70706944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 織田克利 (30359608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 河津正人 (20401078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 山本陽子 (30376644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. HIRAIKE Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
9. MORI Mayuyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
10. ITO Taichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 筒井和義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 川名敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 浦田陽子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中川俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 藤澤貴央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 永江玄太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 太田誠一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 浜本隆二

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 金子修三

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. 小松正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 鶴賀哲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
22. 長阪一憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 浅田健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 浅田佳代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SONE KENBUN 曾根 献文

Sone Kenbun 曾根 献文

SONE Kembun 曾根 献文

Research Projects

Research Products

Co-Researchers

Diagnostics of methylation-based predictive biomarkers in ovarian and endometrial carcinomas by using both tumors and liquid biopsy

Principal Investigator

Project Period (FY)

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DNA損傷関連RNPによる相分離機構の解明と卵巣がん治療への応用

Principal Investigator

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Review Section

Research Institution

Novel therapeutic strategies using histone modifications and DNA repair pathways in refractory gynecological cancerPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Comprehensive Analysis of the Histone Methylation and Endogenous Retrovirus Network in Gynecologic Cancers

Principal Investigator

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Review Section

Research Institution

Radiomics and Radiogenomics Analysis Using Deep Learning in Ovarian Cancer

Principal Investigator

Project Period (FY)

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Research Institution

Multimodal analysis of chromatin 3D structure using deep learning in gynecological malignanciesPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Comprehensive analysis and novel epigenomic drug discovery using ChIP sequence in ovarian clear cell adenocarcinoma.Principal Investigator

Principal Investigator

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Research Institution

A Project Developing a New Cancer Therapy Targeting Histone Methyltransferase and Demethylase in ovarian cancer and endometrial cancerPrincipal Investigator

Principal Investigator

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Research Institution

Development of anti cancer drug targeting longevity related gene -SIRT1 using nanotechnology.Principal Investigator

Principal Investigator

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Research Institution

[Journal Article] Cyclin E1 overexpression sensitizes ovarian cancer cells to WEE1 and PLK1 inhibition2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Integrated genomic/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin2024

Author(s)

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DOI

Data Source

[Journal Article] The automatic diagnosis artificial intelligence system for preoperative magnetic resonance imaging of uterine sarcoma2024

Author(s)

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DOI

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[Journal Article] Inhibition of protein arginine methyltransferase 6 activates interferon signaling and induces the apoptosis of endometrial cancer cells via histone modification2024

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SONE KENBUN 曾根献文

Sone Kenbun 曾根献文

SONE Kembun 曾根献文