Kawakita Fumihiro 川北文博

Researcher Number	90608952
Other IDs
Affiliation (Current)	2025: 三重大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2023: 三重大学, 医学部附属病院, 助教 2020 – 2022: 三重大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator くも膜下出血 / 出血性脳卒中 / ハプトグロビン / ヘモグロビン / 癲癇 / マウス / NCSz / perampanel / SAH / テネイシンC / 神経細胞アポトーシス / 早期脳損傷 / てんかん

遊離型ヘモグロビンの無毒化による出血性脳卒中後の続発性脳損傷抑制法の開発Principal Investigator
- Principal Investigator
  
  川北文博
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Mie University
Elucidation of the pathology of early brain injury after subarachnoid hemorrhage focusing on epilepsyPrincipal Investigator
- Principal Investigator
  
  Kawakita Fumihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Mie University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Anti-Apoptotic Effects of AMPA Receptor Antagonist Perampanel in Early Brain Injury After Subarachnoid Hemorrhage in Mice2023
- Author(s)
  Kawakita F, Nakano F, Kanamaru H, Asada R, Suzuki H
- Journal Title
  
  Transl Stroke Res
  
  Volume: - Pages: 462-475
- DOI
  10.1007/s12975-023-01138-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17963, KAKENHI-PROJECT-22K16684, KAKENHI-PROJECT-21K16605
[Journal Article] Effects of New-Generation Antiepileptic Drug Prophylaxis on Delayed Neurovascular Events After Aneurysmal Subarachnoid Hemorrhage2023
- Author(s)
  Suzuki H, Miura Y, Yasuda R, Yago T, Mizutani H, Ichikawa T, Miyazaki T, Kitano Y, Nishikawa H, Kawakita F, Fujimoto M, Toma N
- Journal Title
  
  Transl Stroke Res
  
  Volume: - Issue: 6 Pages: 899-909
- DOI
  10.1007/s12975-022-01101-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18423, KAKENHI-PROJECT-20K17963, KAKENHI-PROJECT-23K15644
[Journal Article] Epidermal Growth Factor Receptor Mediates Neuronal Apoptosis After Subarachnoid Hemorrhage in Mice2023
- Author(s)
  Nakano F, Kanamaru H, Kawakita F, Liu L, Nakatsuka Y, Nishikawa H, Okada T, Suzuki H
- Journal Title
  
  Stroke
  
  Volume: 54 Issue: 6 Pages: 1616-1626
- DOI
  10.1161/strokeaha.122.041977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15644, KAKENHI-PROJECT-23K15645
[Journal Article] Inflammatory Skin Disease Causes Anxiety Symptoms Leading to an Irreversible Course2023
- Author(s)
  Iida S, Shoji H, Kawakita F, Nakanishi T, Matsushima Y, Kondo M, Habe K, Suzuki H, Miyakawa T, Yamanaka K.
- Journal Title
  
  Int J Mol Sci .
  
  Volume: 21 Issue: 6 Pages: 5942-5942
- DOI
  10.3390/ijms24065942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08379, KAKENHI-PROJECT-20K09346, KAKENHI-PROJECT-23K15644
[Journal Article] Plasma SPARC Elevation in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage2023
- Author(s)
  Nakajima H, Kawakita F, Oinaka H, Suzuki Y, Nampei M, Kitano Y, Nishikawa H, Fujimoto M, Miura Y, Yasuda R, Toma N, Suzuki H; pSEED group
- Journal Title
  
  Neurotherapeutics
  
  Volume: - Issue: 3 Pages: 779-788
- DOI
  10.1007/s13311-023-01351-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18423, KAKENHI-PROJECT-20K17963, KAKENHI-PROJECT-23K15644
[Journal Article] Plasma Fibulin-5 Levels as an Independent Predictor of a Poor Outcome after an Aneurysmal Subarachnoid Hemorrhage2022
- Author(s)
  Suzuki Y, Oinaka H, Nakajima H, Nampei M, Kawakita F, Miura Y, Yasuda R, Toma N, Suzuki H, pSEED Group
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 23 Pages: 15184-15184
- DOI
  10.3390/ijms232315184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] Cerebrovascular pathophysiology of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage2022
- Author(s)
  Suzuki H, Kanamaru H, Kawakita F, Asada R, Fujimoto M, Shiba M
- Journal Title
  
  Histol Histopathol
  
  Volume: 36 Pages: 143-158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] Roles of glutamate in brain injuries after subarachnoid hemorrhage2022
- Author(s)
  Kawakita F, Kanamaru H, Asada R, Suzuki Y, Nampei M, Nakajima H, Oinaka H, Suzuki H
- Journal Title
  
  Histol Histopathol
  
  Volume: 37 Pages: 1041-1051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] Neuroelectric Mechanisms of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage2022
- Author(s)
  Suzuki H, Kawakita F, Asada R
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 6 Pages: 3102-3102
- DOI
  10.3390/ijms23063102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16684, KAKENHI-PROJECT-20K17963
[Journal Article] Higher Plasma Osteopontin Concentrations Associated with Subsequent Development of Chronic Shunt-Dependent Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage2022
- Author(s)
  Asada R, Nakatsuka Y, Kanamaru H, Kawakita F, Fujimoto M, Miura Y, Shiba M, Yasuda R, Toma N, Suzuki H; pSEED group
- Journal Title
  
  Transl Stroke Res
  
  Volume: 12 Issue: 5 Pages: 808-816
- DOI
  10.1007/s12975-020-00886-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] くも膜下出血の治療：現状と展望2022
- Author(s)
  鈴木秀謙、川北文博、浅田玲緒尚、山本篤志、宮崎敬大、山中拓也、佐藤丈典、辻　正範、西川拓文、藤本昌志、三浦洋一、安田竜太、当麻直樹
- Journal Title
  
  脳外誌
  
  Volume: 31 Pages: 513-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] Inhibition of AMPA (α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionate) Receptor Reduces Acute Blood?Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice2021
- Author(s)
  Kawakita Fumihiro、Kanamaru Hideki、Asada Reona、Imanaka-Yoshida Kyoko、Yoshida Toshimichi、Suzuki Hidenori
- Journal Title
  
  Translational Stroke Research
  
  Volume: 13 Issue: 2 Pages: 326-337
- DOI
  10.1007/s12975-021-00934-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07662, KAKENHI-PROJECT-20K17963, KAKENHI-PROJECT-22K16684
[Journal Article] Clarithromycin Ameliorates Early Brain Injury After Subarachnoid Hemorrhage via Suppressing Periostin-Related Pathways in Mice2021
- Author(s)
  Kanamaru H, Kawakita F, Nishikawa H, Nakano F, Asada R, Suzuki H
- Journal Title
  
  Neurotherapeutics
  
  Volume: 18 Issue: 3 Pages: 1880-1890
- DOI
  10.1007/s13311-021-01050-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18423, KAKENHI-PROJECT-20K17963
[Journal Article] くも膜下出血後に発現するマトリセルラー蛋白間の関係と早期脳損傷2020
- Author(s)
  中野芙美、西川拓文、中塚慶徳、川北文博、金丸英樹、岡田　健、芝　真人、鈴木秀謙
- Journal Title
  
  脳血管攣縮
  
  Volume: 36 Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] Prognostic factors varying with age in patients with aneurysmal subarachnoid hemorrhage2020
- Author(s)
  Kanamaru Hideki、Kawakita Fumihiro、Asada Reona、Miura Yoichi、Shiba Masato、Toma Naoki、Suzuki Hidenori
- Journal Title
  
  Journal of Clinical Neuroscience
  
  Volume: 76 Pages: 118-125
- DOI
  10.1016/j.jocn.2020.04.022
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] 重症くも膜下出血に対する治療2020
- Author(s)
  鈴木秀謙、川北文博、金丸英樹、浅田玲緒尚、藤本昌志、三浦洋一、芝　真人、当麻直樹
- Journal Title
  
  脳外誌
  
  Volume: 29 Pages: 109-115
- NAID
  130007801707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] Periostin in cerebrovascular disease2020
- Author(s)
  Kawakita Fumihiro、Suzuki Hidenori
- Journal Title
  
  Neural Regeneration Research
  
  Volume: 15 Issue: 1 Pages: 63-63
- DOI
  10.4103/1673-5374.264456
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] マウスくも膜下出血モデルにおけるぺランパネルの脳保護効果2020
- Author(s)
  川北文博、金丸英樹、浅田玲緒尚、中塚慶徳、三浦洋一、芝　真人、安田竜太、毛利元信、畑崎聖二、当麻直樹、鈴木秀謙
- Journal Title
  
  脳血管攣縮
  
  Volume: 36 Pages: 126-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17963
[Journal Article] マウスくも膜下出血モデルにおけるクラリスロマイシン投与による脳保護効果とペリオスチンの発現変化2020
- Author(s)
  金丸英樹、川北文博、西川拓文、中野芙美、浅田玲緒尚、鈴木秀謙
- Journal Title
  
  脳血管攣縮
  
  Volume: 36 Pages: 123-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] マウスくも膜下出血後早期脳損傷に対するハプトグロビンの脳保護効果2024
- Author(s)
  川北文博、老中博紀、中島英貴、南平麻衣、鈴木有芽、鈴木秀謙
- Organizer
  第40回SAH/スパズム・シンポジウム
- Data Source
  KAKENHI-PROJECT-23K15644
[Presentation] Secreted protein acidic and rich in cysteine (SPARC) はくも膜下出血後の遅発性脳虚血において上昇する2023
- Author(s)
  中島英貴、川北文博、鈴木秀謙
- Organizer
  第39回SAH/スパズム・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] くも膜下出血後の脳血管攣縮と血中 Periostin 濃度との関連2023
- Author(s)
  老中博紀、川北文博、鈴木秀謙
- Organizer
  第39回SAH/スパズム・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] マウスくも膜下出血モデルにおけるハプトグロビン投与による脳血管攣縮抑制効果2023
- Author(s)
  川北文博、鈴木秀謙
- Organizer
  第39回SAH/スパズム・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] 動脈瘤性くも膜下出血後の血中 PEDF 濃度上昇は転帰不良と関連する2023
- Author(s)
  南平麻衣、川北文博、鈴木秀謙
- Organizer
  第48回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] 脳動脈瘤破裂によるくも膜下出血と血漿 Fibulin-5濃度との関連2023
- Author(s)
  鈴木有芽、川北文博、鈴木秀謙
- Organizer
  第48回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] マウスくも膜下出血モデルにおけるハプトグロビン投与によるTNC発現抑制を介した脳血管攣縮抑制効果2023
- Author(s)
  川北文博、老中博紀、中島英貴、南平麻衣、鈴木有芽、鈴木秀謙
- Organizer
  第9回 MatriCell フォーラム
- Data Source
  KAKENHI-PROJECT-23K15644
[Presentation] マウスくも膜下出血モデルにおける上皮成長因子受容体阻害剤の神経アポトーシス抑制効果の検討2022
- Author(s)
  中野芙美、金丸英樹、川北文博、劉　磊、中塚慶徳、西川拓文、岡田　健、芝　真人、鈴木秀謙
- Organizer
  第22回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] マウスくも膜下出血モデルにおけるAMPA受容体拮抗薬の脳保護効果2022
- Author(s)
  川北文博、浅田玲緒尚、三浦洋一、安田竜太、当麻直樹、鈴木秀謙
- Organizer
  第22回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] マウスくも膜下出血後早期脳損傷におけるAMPA型グルタミン酸受容体の役割2021
- Author(s)
  川北文博
- Organizer
  Stroke 2021 (第37回スパズム・シンポジウム)
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] マウスくも膜下出血モデルにおけるperampanelの脳保護効果2020
- Author(s)
  川北文博、金丸英樹、浅田玲緒尚、中塚慶徳、三浦洋一、芝　真人、安田竜太、毛利元信、畑崎聖二、当麻直樹、鈴木秀謙
- Organizer
  第36回スパズム・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] Tenascin-C: A Novel Therapeutic Target in Subarachnoid Hemorrhage2020
- Author(s)
  Masato Shiba, Masashi Fujimoto, Naoki Toma, Yoichi Miura, Fumihiro Kawakita, Yume Suzuki, Yusuke Kuroda, Munenari Ikezawa, Reona Asada, Hideki Kanamaru, Hidenori Suzuki
- Organizer
  International Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] くも膜下出血の年代別予後因子についての検討2020
- Author(s)
  川北文博、鈴木秀謙
- Organizer
  第25回日本脳神経外科救急学会
- Data Source
  KAKENHI-PROJECT-20K17963
[Presentation] 脳血管攣縮Update（基礎研究領域）2020
- Author(s)
  鈴木秀謙、川北文博
- Organizer
  一般社団法人日本脳神経外科学会第79回学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17963

1. 西川拓文

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 吉田利通

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山中恵一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 波部幸司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 近藤誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 浅田玲緒尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawakita Fumihiro 川北 文博

Research Projects

Research Products

Co-Researchers

遊離型ヘモグロビンの無毒化による出血性脳卒中後の続発性脳損傷抑制法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathology of early brain injury after subarachnoid hemorrhage focusing on epilepsyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Anti-Apoptotic Effects of AMPA Receptor Antagonist Perampanel in Early Brain Injury After Subarachnoid Hemorrhage in Mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of New-Generation Antiepileptic Drug Prophylaxis on Delayed Neurovascular Events After Aneurysmal Subarachnoid Hemorrhage2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epidermal Growth Factor Receptor Mediates Neuronal Apoptosis After Subarachnoid Hemorrhage in Mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inflammatory Skin Disease Causes Anxiety Symptoms Leading to an Irreversible Course2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasma SPARC Elevation in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasma Fibulin-5 Levels as an Independent Predictor of a Poor Outcome after an Aneurysmal Subarachnoid Hemorrhage2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebrovascular pathophysiology of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage2022

Author(s)

Journal Title

Data Source

[Journal Article] Roles of glutamate in brain injuries after subarachnoid hemorrhage2022

Author(s)

Journal Title

Data Source

[Journal Article] Neuroelectric Mechanisms of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Higher Plasma Osteopontin Concentrations Associated with Subsequent Development of Chronic Shunt-Dependent Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] くも膜下出血の治療：現状と展望2022

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of AMPA (α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionate) Receptor Reduces Acute Blood?Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clarithromycin Ameliorates Early Brain Injury After Subarachnoid Hemorrhage via Suppressing Periostin-Related Pathways in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] くも膜下出血後に発現するマトリセルラー蛋白間の関係と早期脳損傷2020

Author(s)

Kawakita Fumihiro 川北文博