Arai Yoshikazu 新井良和

… Alternative Names

ARAI Yoshikazu 新井良和

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Researcher Number	90614769
Other IDs
Affiliation (Current)	2025: 宮崎大学, 農学部, 准教授 2025: 明治大学, 研究・知財戦略機構, 研究推進員(ポスト・ドクター)
Affiliation (based on the past Project Information) *help	2016 – 2024: 宮崎大学, 農学部, 助教 2016: 明治大学, 研究・知財戦略機構, 研究推進員(ポスト・ドクター) 2015: 明治大学, 研究・知財戦略機構, 研究推進員 2012 – 2015: 明治大学, 公私立大学の部局等, 研究員 2013: 明治大学, 研究・知財戦略機構, 研究推進員
Review Section/Research Field	Principal Investigator Basic Section 64010:Environmental load and risk assessment-related / Risk sciences of radiation and chemicals Except Principal Investigator General surgery
Keywords	Principal Investigator 環境化学物質 / エピジェネティクス / 自閉症 / DNAメチル化 / 化学物質 / 神経分化 / 機械学習 / 自閉スペクトラム症 / SHANK3 / ヒトiPS細胞 … More / 神経 / 神経幹細胞 / iPS細胞 / 発生・分化 / 動物 / 有害化学物質 / 肥満 / 前駆脂肪細胞 / 脂肪細胞 / 脂肪細胞肥大化 … More Except Principal Investigator 膵島移植 / 膵ランゲルハンス島 / 糖尿病 / 膵島シート / ガラス化凍結 / 凍結保存 / 膵頭シート / ヒト糖尿病モデルモデル / 赤紫蛍光蛋白Plum / ヒト糖尿病モデル / クローンブタ / 膵ランゲルハンス糖 / 移植 / 拒絶 / トランスジェニックブタ / パーソナライズド / エピゲノム / ヒト糖尿病類似モデルブタ / 免疫抑制剤 Less

化学物質による自閉症発症リスクの解明：機械学習によるエピジェネティック変異解析Principal Investigator
- Principal Investigator
  
  新井良和
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  University of Miyazaki
Risk assessment of chemical-induced autism: epigenetic mutation analysis of SHANK3Principal Investigator
- Principal Investigator
  
  ARAI YOSHIKAZU
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  University of Miyazaki
A risk assessment of autism caused by environmental chemicals using epigenetic informationPrincipal Investigator
- Principal Investigator
  
  ARAI YOSHIKAZU
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  University of Miyazaki
A risk assessment of adipocyte hypertrophy caused by environmental chemicals based on epigenetic informationPrincipal Investigator
- Principal Investigator
  
  ARAI YOSHIKAZU
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  University of Miyazaki
Establishing a new cryopreservation method for pig pancreatic islet sheet by vitrification and an evaluation method by a high-throughput sequencing.
- Principal Investigator
  
  Masaki Nagaya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Meiji University
A transgenic-cloned pig model expressing fluorescent or non-fluorescent modified Plum gene for the evaluation of islet transplantation
- Principal Investigator
  
  Masaki Nagaya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Meiji University
A new selection system of suitable immunosuppressive drugs for each pancreatic islet transplantation using epigenetic analysis in a three-dimensional culture system
- Principal Investigator
  
  MASAKI NAGAYA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Meiji University

All 2023 2020 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Epigenetic mutagen-like environmental chemicals alter neural differentiation of human induced pluripotent stem cells2023
- Author(s)
  Arai Yoshikazu、Nishino Koichiro
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 48 Issue: 11 Pages: 571-583
- DOI
  10.2131/jts.48.571
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12277, KAKENHI-PROJECT-21H02381
[Journal Article] DNA methylation ambiguity in the Fibrillin-1 (FBN1) CpG island shore possibly involved in Marfan syndrome2020
- Author(s)
  Arai Y, Umeyama K, Okazaki N, Nakano K, Nishino K, Nagashima H, and Ohgane J
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 5287-5287
- DOI
  10.1038/s41598-020-62127-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11679
[Journal Article] Evidence of exposure to chemicals and heavy metals during pregnancy in Japanese women2017
- Author(s)
  Maekawa Ryo、Ito Rie、Iwasaki Yusuke、Saito Koichi、Akutsu Kazuhiko、Takatori Satoshi、Ishii Rie、Kondo Fumio、Arai Yoshikazu、Ohgane Jun、Shiota Kunio、Makino Tsunehisa、Sugino Norihiro
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 16 Issue: 4 Pages: 337-348
- DOI
  10.1002/rmb2.12049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-15H02480, KAKENHI-PROJECT-16K16193
[Journal Article] DNA hypermethylation enhanced telomerase reverse transcriptase expression in human-induced pluripotent stem cells.2017
- Author(s)
  Takasawa K, Arai Y, Yamazaki-Inoue M, Toyoda M, Akutsu H, Umezawa A, Nishino K.
- Journal Title
  
  Human Cell
  
  Volume: 31 Issue: 1 Pages: 78-86
- DOI
  10.1007/s13577-017-0190-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01588, KAKENHI-PROJECT-15J11596, KAKENHI-PROJECT-16K15055, KAKENHI-PROJECT-16K16193
[Journal Article] Establishment of DNA methylation patterns of the <i>Fibrillin1</i> (<i>FBN1</i>) gene in porcine embryos and tissues2017
- Author(s)
  Arai Y, Umeyama K, Takeuchi K, Okazaki N, Hichiwa N, Yashima S, Nakano K, Nagashima H, Ohgane J
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 63 Issue: 2 Pages: 157-165
- DOI
  10.1262/jrd.2016-158
- NAID
  130007314629
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-15H02480, KAKENHI-PROJECT-16K16193
[Journal Article] A transgenic-cloned pig model expressing non-fluorescent modified Plum.2016
- Author(s)
  Nagaya M, Watanabe M, Kobayashi M, Nakano K, Arai Y, Asano Y, Takeishi T, Umeki I, Fukuda T, Yashima S, Takayanagi S, Watanabe N, Onodera M, Matsunari H, Umeyama K, Nagashima H.
- Journal Title
  
  J Reprod Dev.
  
  Volume: 62 Pages: 511-520
- NAID
  130005431253
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15480
[Journal Article] A New System to Evaluate the Influence of Immunosuppressive Drugs on Pancreatic Islets Using Epigenetic Analysis in a 3-Dimensional Culture.2015
- Author(s)
  Nagaya M, Arai Y, Matsunari H, Honda M, Nakano K, Maehara M, Sugimoto N, Kobayashi M, Sakai R, Asano Y, Watanabe M, Umeyama K, Nagashima H.
- Journal Title
  
  Pancreas.
  
  Volume: 44 Issue: 5 Pages: 778-85
- DOI
  10.1097/mpa.0000000000000366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293279
[Journal Article] Generation of interleukin-2 receptor gamma gene knockout pigs from so matic cells genetically modified by zinc finger nuclease-encoding mRNA.2013
- Author(s)
  Watanabe M, Nakano K, Matsunari H, Matsuda T, Maehara M, Kanai T, Kobayashi M, Matsumura Y, Sakai R, Kuramoto M, Hayashida G, Asano Y, Takayanagi S, Arai Y, Umeyama K., Nagaya M, Hanazono Y, Nagashima H
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 10 Pages: e76478-e76478
- DOI
  10.1371/journal.pone.0076478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J06509, KAKENHI-PROJECT-25293279
[Presentation] ブタにおける OTC 欠損症原因遺伝子のエピジェネティック解析2018
- Author(s)
  茂田遼平, 新井良和, 松成ひとみ, 長嶋比呂志, 大鐘潤
- Organizer
  第124回日本畜産学会
- Data Source
  KAKENHI-PROJECT-16K16193
[Presentation] DNA メチル化によるブタ MSTN 遺伝子の組織特異的発現調節機構の解析2018
- Author(s)
  隠地健斗, 新井良和, 長嶋比呂志, 大鐘潤
- Organizer
  第124回日本畜産学会
- Data Source
  KAKENHI-PROJECT-16K16193
[Presentation] アリルごとのDNAメチル化に着目したエピジェネティクス解析の新たな試み2017
- Author(s)
  大鐘潤, 新井良和
- Organizer
  日本農芸化学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K16193
[Presentation] エピジェネティクスによる遺伝病発症機序解明への新たなアプローチ2016
- Author(s)
  新井良和
- Organizer
  明治大学・聖マリアンナ医科大学共同研究会
- Place of Presentation
  神奈川県
- Invited
- Data Source
  KAKENHI-PROJECT-16K16193
[Presentation] ハプロ不全優性遺伝病の発症機序解明に向けた新たなアプローチ：ブタフィブリリン1 (Fbn1)のエピジェネティック解析2016
- Author(s)
  新井良和、梅山一大、竹内健太、八島紗耶香、中野和明、長嶋比呂志、大鐘潤
- Organizer
  第109回日本繁殖生物学会大会
- Place of Presentation
  神奈川県
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-16K16193
[Presentation] Generation and characterization of transgenic-cloned pigs expressing the far-red fluorescent protein monomeric plum.2014
- Author(s)
  Kobayashi M, Watanabe M, Matsunari H, Nakano K, Kanai T, Hayashida G, Matsumura Y, Kuramoto M, Sakai R, Arai Y, Umeyama K, Watanabe N, Onodera M, Nagaya M, Nagashima H.
- Organizer
  40th Annual Conference of the International Embryo Transfer Society
- Place of Presentation
  Reno, USA.
- Data Source
  KAKENHI-PROJECT-25293279
[Presentation] 細胞周期可視化蛍光プローブFucci を発現するブタ体細胞核移植胚の作出.2013
- Author(s)
  林田豪太, 渡邊将人, 松成ひとみ, 中野和明, 金井貴博, 小林美里奈, 松村幸奈, 倉本桃子, 坂井理恵子, 浅野吉則, 内倉鮎子, 前原美樹, 新井良和, 梅山一大, 長屋昌樹, 沢野朝子, 宮脇敦史, 長嶋比呂志.
- Organizer
  第106回日本繁殖生物学会大会.
- Place of Presentation
  東京.
- Data Source
  KAKENHI-PROJECT-25293279
[Presentation] 異種移植研究における遺伝子改変ブタの作出への人工生殖技術の利用.2013
- Author(s)
  坂井理恵子, 中野和明, 松成ひとみ, 新井良和, 渡邊將人, 梅山一大, 佐原寿史, 山田和彦, 長屋昌樹, 宮川周士, 長嶋比呂志.
- Organizer
  第1回日本先進医工学ブタ研究会.
- Place of Presentation
  大阪.
- Data Source
  KAKENHI-PROJECT-25293279
[Presentation] Application of blastocyst complementation to development of genetically modified pigs for xenotransplantation.2013
- Author(s)
  Nakano K, Matsunari H, Matsuda T, Kanai T, Hayashida G, Matsumura K, Kobayashi M, Kuramoto M, Asano Y, Sakai R, Uchikura A, Arai Y, Watanabe M, Umeyama K, Nagaya M, Nagashima H.
- Organizer
  12th Congress of International Xenotransplantation Association (IXA).
- Place of Presentation
  Osaka, Japan.
- Data Source
  KAKENHI-PROJECT-25293279
[Presentation] 遺伝子改変クローンブタ開発における人工生殖技術を利用した遺伝的バックグラウンドの更新.2013
- Author(s)
  坂井理恵子, 中野和明, 松成ひとみ, 新井良和, 渡邊將人, 梅山一大, 長屋昌樹, 宮川周士, 長嶋比呂志.
- Organizer
  第16回日本異種移植研究会.
- Place of Presentation
  大阪.
- Data Source
  KAKENHI-PROJECT-25293279
[Presentation] Zinc finger nuclease発現mRNAによるIL2RG遺伝子ノックアウトブタの作出.2013
- Author(s)
  渡邊將人, 中野和明, 松成ひとみ, 松田泰輔, 金井貴博, 小林美里奈, 松村幸奈, 坂井理恵子, 倉本桃子, 林田豪太, 浅野吉則, 高柳就子, 新井良和, 梅山一大, 長屋昌樹, 豊花, 長嶋比呂志
- Organizer
  第36回日本分子生物学会.
- Place of Presentation
  神戸.
- Data Source
  KAKENHI-PROJECT-25293279
[Presentation] Development of a feasible verification system for pluripotent stem cells using porcine parthenogenetic embryos2012
- Author(s)
  Nakano K, Watanabe M, Matsunari H, Matsuda T, Honda K, Maehara M, Kanai T, Arai Y, Umeyama K, Fu j i shiro S, Nagaya M, Nagashima H
- Organizer
  10^<th> International Societ for Stem Cell Research
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24659596
[Presentation] ブタ単為発生胚を用いた凝集キメラ作出法2012
- Author(s)
  中野和明、渡邊將人、松成ひとみ、松田泰輔、本田香澄、前原美樹、竹内靖浩、金井貴博、新井良和、梅山一大、藤城修平、長屋昌樹、花園豊、長嶋比呂志
- Organizer
  第105回日本繁殖生物学会大会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-24659596
[Presentation] Development of a feasible verification system for pluripotent stem cells using porcine parthenogenetic embryos2012
- Author(s)
  Nakano K, Watanabe M, Matsunari H, Matsuda T, Honda K, Maehara M, Kanai T, Arai Y, Umeyama K, Fujishiro S, Nagaya M, Nagaya M, Nagashima H
- Organizer
  10th　International Society for Stem Cell Research
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24659596
[Presentation] ブタ単為発生胚を用いた凝集キメラ作出法2012
- Author(s)
  中野和明、渡邊將人、松成ひとみ、松田泰輔、本田香澄、前原美樹、竹内靖浩、金井貴博、新井良和、梅山一大、藤城修平、水上善久、長屋昌樹、花園豊、長嶋比呂志
- Organizer
  第105回日本繁殖生物学会大会
- Place of Presentation
  つくば市、筑波大学
- Data Source
  KAKENHI-PROJECT-24659596
[Presentation] 細胞周期可視化蛍光プローブFucci導入トランスジェニック・クローンブタの作出
- Author(s)
  3.渡邊將人, 林田豪太, 松成ひとみ, 中野和明, 小林美里奈, 松村幸奈, 倉本桃子, 坂井理恵子, 浅野吉則, 内倉鮎子, 新井良和, 梅山一大, 長屋昌樹, 阪上‐沢野朝子, 宮脇敦史, 長嶋比呂志
- Organizer
  第107回日本繁殖生物学会大会
- Place of Presentation
  帯広
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25293279

1. WATANABE Masato (00321688)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. MASAKI NAGAYA (90329300)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
3. NAGASHIMA Hiroshi (50318664)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
4. UMEYAMA Kazuhiro (70342699)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. MATSUNARI HITOMI (70639517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. OHGANE Jun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ITO Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. Kondo Masayo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. AKUTSU Hidenori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Arai Yoshikazu 新井 良和

ARAI Yoshikazu 新井 良和

Research Projects

Research Products

Co-Researchers

化学物質による自閉症発症リスクの解明：機械学習によるエピジェネティック変異解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Risk assessment of chemical-induced autism: epigenetic mutation analysis of SHANK3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A risk assessment of autism caused by environmental chemicals using epigenetic informationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A risk assessment of adipocyte hypertrophy caused by environmental chemicals based on epigenetic informationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishing a new cryopreservation method for pig pancreatic islet sheet by vitrification and an evaluation method by a high-throughput sequencing.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A transgenic-cloned pig model expressing fluorescent or non-fluorescent modified Plum gene for the evaluation of islet transplantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new selection system of suitable immunosuppressive drugs for each pancreatic islet transplantation using epigenetic analysis in a three-dimensional culture system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Epigenetic mutagen-like environmental chemicals alter neural differentiation of human induced pluripotent stem cells2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] DNA methylation ambiguity in the Fibrillin-1 (FBN1) CpG island shore possibly involved in Marfan syndrome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evidence of exposure to chemicals and heavy metals during pregnancy in Japanese women2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA hypermethylation enhanced telomerase reverse transcriptase expression in human-induced pluripotent stem cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of DNA methylation patterns of the <i>Fibrillin1</i> (<i>FBN1</i>) gene in porcine embryos and tissues2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] A transgenic-cloned pig model expressing non-fluorescent modified Plum.2016

Author(s)

Journal Title

Arai Yoshikazu 新井良和

ARAI Yoshikazu 新井良和