Jin Yonghui 金永輝

… Alternative Names

JIN Younghui 金永輝

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Researcher Number	90620344
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 京都大学, 医生物学研究所, 助教 2019 – 2020: 京都大学, ウイルス・再生医科学研究所, 助教 2015 – 2018: 京都大学, 医学研究科, 特定助教 2015: 京都大学, 医学(系)研究科(研究院), 特定助教 2015: 京都大学, 医学部付属病院, 助教 2014: 京都大学, 再生医科学研究所, 研究員 2013: 京都大学, iPS細胞研究所, 研究員
Review Section/Research Field	Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56020:Orthopedics-related Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 異所性骨化 / 進行性骨化性線維異形成症 / 空間的トランスオミックス解析 / エネルギー代謝 / イメージング質量分析 / 空間的遺伝子発現解析 / 疾患iPS細胞 / 進行性骨化性線維異形成症異 / 進行性骨化性繊維異形成症 / mTOR … More / FOP / RIPアッセイ / 軟骨分化誘導 / 翻訳制御機構 / 分化段階特異的 / iPS細胞 / 翻訳制御 / 軟骨分化 … More Except Principal Investigator iPS細胞 / 軟骨形成性腫瘍 / IDH遺伝子 / 軟骨形成腫瘍 / 軟骨肉腫 / IDH1遺伝子 / ゲノム編集 / 強直性脊椎炎 / 血清反応陰性関節炎 / CXCL13 / CRISPR-Cas9 / 遺伝子編集 / HLA B27 / 血清反応陰性脊椎関節炎 / 中胚葉細胞 / ヒストンメチル化 / 神経幹細胞 / 間葉系幹細胞 / 軟骨腫瘍 / p16 / iPSC / IDH / chondrosarcoma / 細胞間相互作用 / 成長板軟骨細胞 / 成長軟骨 / NLRP3 / CINCA症候群 / トランスクリプトーム解析 / エピゲノム解析 / 人工多能性幹細胞 / 遺伝子変異 / イソクエン酸デヒドロゲナーゼ / isocitrate dehydorgenase / oncometabolite Less

Spatial trans-omics analysis of heterotopic ossification process and disease applicationPrincipal Investigator
- Principal Investigator
  
  Jin Yonghui
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto University
Elucidation of mechanism underlying the chondrogenesis-specific translational regulationPrincipal Investigator
- Principal Investigator
  
  JIN YONGHUI
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto University
Mechanism analysis of heterotopic ossification formation in Fibrodysplasia Ossificans Progressiva (FOP)Principal Investigator
- Principal Investigator
  
  Jin Yonghui
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kyoto University
Comprehensive understanding of spatio-temporal effects of mutant IDH1 during the development of cartilage forming tumors
- Principal Investigator
  
  Toguchida Junya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kyoto University
Pathogenesis elucidation of seronegative spondyloarthritis using patient-derived iPSCs
- Principal Investigator
  
  Yoshitomi Hiroyuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Functional analyses of mutant NLRP3 on the growth and differentiation of growth plate chondrocytes
- Principal Investigator
  
  Toguchida Junya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Investigation of functional roles of mutant IDH as specific mutations in cartilage-forming tumors and its application for the development of treatment
- Principal Investigator
  
  Toguchida Junya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Derivation of human PSC-derived mesodermal cells
- Principal Investigator
  
  Ikeya Makoto
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
The research on the contribution of mutant IDH gene to the formation of cartilagenous tumors
- Principal Investigator
  
  OKAMOTO Takeshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Oxidative phosphorylation is a pivotal therapeutic target of fibrodysplasia ossificans progressiva2024
- Author(s)
  Sun Liping、Jin Yonghui、Nishio Megumi、Watanabe Makoto、Kamakura Takeshi、Nagata Sanae、Fukuda Masayuki、Maekawa Hirotsugu、Kawai Shunsuke、Yamamoto Takuya、Toguchida Junya
- Journal Title
  
  Life Science Alliance
  
  Volume: 7 Issue: 5 Pages: e202302219-e202302219
- DOI
  10.26508/lsa.202302219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19600
[Journal Article] 3D osteogenic differentiation of human iPSCs reveals the role of TGFβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes2023
- Author(s)
  Kawai Shunsuke、Sunaga Junko、Nagata Sanae、Nishio Megumi、Fukuda Masayuki、Kamakura Takeshi、Sun Liping、Jin Yonghui、Sakamoto Satoko、Watanabe Akira、Matsuda Shuichi、Adachi Taiji、Toguchida Junya
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1094-1094
- DOI
  10.1038/s41598-023-27556-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19600, KAKENHI-PROJECT-20H00659
[Journal Article] Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human iPSC-Derived Chondrocytes2023
- Author(s)
  Kamakura Takeshi、Jin Yonghui、Nishio Megumi、Nagata Sanae、Fukuda Masayuki、Sun Liping、Kawai Shunsuke、Toguchida Junya
- Journal Title
  
  JBMR Plus
  
  Volume: e10737 Issue: 5
- DOI
  10.1002/jbm4.10737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19600
[Journal Article] Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs2022
- Author(s)
  Maekawa Hirotsugu、Jin Yonghui、Nishio Megumi、Kawai Shunsuke、Nagata Sanae、Kamakura Takeshi、Yoshitomi Hiroyuki、Niwa Akira、Saito Megumu K.、Matsuda Shuichi、Toguchida Junya
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 17 Issue: 1
- DOI
  10.1186/s13023-022-02506-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19600
[Journal Article] Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR12020
- Author(s)
  Maekawa Hirotsugu、Kawai Shunsuke、Nishio Megumi、Nagata Sanae、Jin Yonghui、Yoshitomi Hiroyuki、Matsuda Shuichi、Toguchida Junya
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 15 Issue: 1 Pages: 122-122
- DOI
  10.1186/s13023-020-01406-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02928, KAKENHI-PROJECT-18H02929
[Journal Article] In vitro bone-like nodules generated from patient-derived iPSCs recapitulate pathological bone phenotypes2019
- Author(s)
  Kawai Shunsuke、Yoshitomi Hiroyuki、Sunaga Junko、Alev Cantas、Nagata Sanae、Nishio Megumi、Hada Masataka、Koyama Yuko、Uemura Maya、Sekiguchi Kazuya、Maekawa Hirotsugu、Ikeya Makoto、Tamaki Sakura、Jin Yonghui、Harada Yuki、Fukiage Kenichi、Adachi Taiji、Matsuda Shuichi、Toguchida Junya
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 3 Issue: 7 Pages: 558-570
- DOI
  10.1038/s41551-019-0410-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02928, KAKENHI-PROJECT-18H02929, KAKENHI-PROJECT-18K19614
[Journal Article] SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier.2015
- Author(s)
  Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T Jr, Toguchida J.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 11 Pages: e0142991-e0142991
- DOI
  10.1371/journal.pone.0142991
- NAID
  120005749920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04956
[Journal Article] Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.2015
- Author(s)
  Jin Y, Elalaf H, Watanabe M, Tamaki S, Hineno S, Matsunaga K, Woltjen K, Kobayashi Y, Nagata S, Ikeya M, Kato T Jr, Okamoto T, Matsuda S, Toguchida J.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 7 Pages: e0131998-e0131998
- DOI
  10.1371/journal.pone.0131998
- NAID
  120005756272
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] New Therapeutic Approach Targeting Energy metabolism of Fibrodysplasia Ossification Progressiva (FOP)2024
- Author(s)
  Liping Sun, Yonghui Jin, Megumi Nishio, Junya Toguchida.
- Organizer
  International Conference on Interdisciplinary Life Sciences 2023 (ILS2023)
- Data Source
  KAKENHI-PROJECT-22K19600
[Presentation] エネルギー代謝を標的とした進行性骨化性線維異形成症に対する新規治療法の検討2023
- Author(s)
  孫麗萍、金永輝、西尾恵、鎌倉武史、戸口田淳也
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19600
[Presentation] Loss of collagen X facilitates hypertrophic differentiation and endochondral ossification of human iPSC-derived chondrocytes2022
- Author(s)
  Takeshi Kamakura, Megumi Nishio, Sanae Nagata, Yonghui Jin, Junya Toguchida
- Organizer
  第４５回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19600
[Presentation] New Therapeutic Approach Targeting Energy metabolism of Fibrodysplasia Ossification Progressiva (FOP)2022
- Author(s)
  Liping Sun,, Yonghui Jin, Megumi Nishio, Masami Nakateke, Sanae Nagata, Takeshi Kamakura, Junya Toguchida
- Organizer
  第４５回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19600
[Presentation] 患者由来iPS細胞を用いたCamurati-Engelmann病の病態解析2020
- Author(s)
  前川裕継、川井俊介、金永輝、西尾恵、永田早苗、古庄知己、道上敏美、池川志郎、松田秀一、戸口田淳也
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 変異型IDH1は通常酸素下において癌遺伝子誘導性細胞老化を引き起こす2020
- Author(s)
  鎌倉武史、金永輝、玉置さくら、渡辺真、岡本健、吉富啓之、戸口田淳也
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 変異型IDH1は通常酸素下において癌遺伝子誘導性細胞老化を引き起こす2020
- Author(s)
  鎌倉　武史、金永輝、玉置さくら、渡辺真、岡本健、吉富啓之、戸口田淳也
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] 変異型IDH1は通常酸素下において癌遺伝子誘導性細胞老化を引き起こす2020
- Author(s)
  鎌倉武史、金永輝、玉置さくら、渡辺真、岡本健、吉富啓之、戸口田淳也
- Organizer
  第79回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 異所性骨化のメカニズムとその制御2020
- Author(s)
  戸口田淳也、金永輝、孫麗萍、川井俊介、前川裕継
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] Application of pluripotent stem cells for in vitro sarcomagenesis2020
- Author(s)
  Tamaki S, Nagata S, Jin Y, Yoshitomi H, Toguchida J
- Organizer
  第79回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 変異型IDH1は通常酸素下において癌遺伝子誘導性細胞老化を引き起こす2020
- Author(s)
  鎌倉武史、金永輝、玉置さくら、渡辺真、岡本健、吉富啓之、戸口田淳
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] Application of pluripotent stem cells for in vitro sarcomagenesis2020
- Author(s)
  Tamaki S, Nagata S, Jin Y, Yoshitomi H, Toguchida J
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] Prophylactic treatment of rapamycin ameliorates naturally developing and episode-induced heterotopic ossification in mice expressing human mutant ACVR12020
- Author(s)
  Maekawa H, Kawai S, Nshio M, Nagata S, Jin Y, Yoshitomi H, Matsuda S, Toguchida J
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 進行性骨化性線維異形成症における異所性骨化形成機構の解析2020
- Author(s)
  金永輝、吉富啓之、西尾恵、鎌倉武史、玉置さくら、孫麗萍、戸口田淳也
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 進行性骨化性線維異形成症におけるミトコンドリアのエネルギー代謝を標的とした新規治療法の検討2020
- Author(s)
  孫麗萍、金永輝、鎌倉武史、玉置さくら、戸口田淳也
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 骨再生機構へのアプローチとしての異所性骨化の解析2020
- Author(s)
  戸口田淳也、金永輝、川井俊介、前川裕継
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 進行性骨化性線維異形成症に対するmTOR阻害剤の有効性の検討2019
- Author(s)
  前川裕継、吉富啓之、川井俊介、金永輝、松田秀一、戸口田淳也
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 進行性骨化性線維異形成症における異所性骨化形成機構の解析2019
- Author(s)
  金永輝、吉富啓之、西尾恵、鎌倉武史、玉置さくら、戸口田淳也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 軟骨形成性腫瘍における変異型IDH1及びp16の機能的意義について2019
- Author(s)
  鎌倉武史、永田早苗、湯川愛友、西尾恵、金永輝、吉富啓之、戸口田淳也
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] 進行性骨化性線維異形成症における異所性骨化形成機構の解析2019
- Author(s)
  金永輝、吉富啓之、,戸口田淳也
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 進行性骨化性線維異形成症に対するmTOR阻害剤の有効性の検討2019
- Author(s)
  前川裕継、吉富啓之、川井俊介、金永輝、西尾恵、永田早苗、松田秀一、戸口田淳也
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18H02928
[Presentation] 進行性骨化性線維異形成症に対するmTOR阻害剤の有効性の検討2019
- Author(s)
  前川裕継、吉富啓之、川井俊介、金永輝、松田秀一、戸口田淳也
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19614
[Presentation] 進行性骨化性線維異形成症における異所性骨化形成機構の解析2019
- Author(s)
  金永輝、吉富啓之、戸口田淳也
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K19614
[Presentation] 進行性骨化性線維異形成症に対するmTOR阻害剤の有効性の検討2019
- Author(s)
  前川裕継、吉富啓之、川井俊介、金永輝、西尾恵、永田早苗、松田秀一、戸口田淳也
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K19614
[Presentation] 多能性幹細胞を用いたin vitro肉腫発生機序解明の試み2019
- Author(s)
  玉置さくら、永田早苗、湯川愛友、西尾恵、金永輝、吉富啓之、戸口田淳也
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] 進行性骨化性線維異形成症における異所性骨化形成機構の解析2019
- Author(s)
  金永輝、吉富啓之、西尾恵、鎌倉武史、玉置さくら、戸口田淳也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19614
[Presentation] Functional significance of mutant IDH1 and p16INK4A in cartilage-forming tumor2019
- Author(s)
  Kamakura T、Jin Y, Tamaki S, Watanabe M, Okamoto T, Yoshitomi H, Toguchida J
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] 滑膜肉腫におけるFZD10を介したシグナル伝達経路とその生物学的意義の解析2018
- Author(s)
  宗圓充、玉置さくら、湯川愛友、鎌倉武史、金永輝、岡本健、吉富啓之、戸口田淳也
- Organizer
  第51回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] 軟骨形成性腫瘍における変異型IDHの機能的意義について2018
- Author(s)
  鎌倉武史、金永輝、玉置さくら、渡辺真、岡本健、吉富啓之、戸口田淳也
- Organizer
  第51回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] In vitroにおける長期的なSS18-SSX融合タンパクの機能評価方法の開発2018
- Author(s)
  玉置さくら、永田早苗、吉富啓之、湯川愛友、宗圓充、鎌倉武史、金永輝、戸口田淳也
- Organizer
  第51回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-18H02929
[Presentation] 多能性幹細胞の肉腫研究への応用2017
- Author(s)
  戸口田淳也、玉置さくら、金永輝、鎌倉武史、吉富啓之
- Organizer
  第76回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] 疾患特異的iPS細胞を活用した骨格疾患の病態解明2016
- Author(s)
  戸口田淳也、日野恭介、池谷真、関口和也、金永輝、岡本健、吉富啓之、松田秀一
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K15549
[Presentation] 多能性幹細胞の肉腫研究への応用2016
- Author(s)
  戸口田淳也、玉置さくら、関口和也、金永輝、岡本健、松田秀一
- Organizer
  第89回日本整形外科学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] 変異型IDH1は遺伝子特異的なヒストン修飾を介して、間葉系幹細胞から軟骨及び骨への分化を脱制御する2016
- Author(s)
  金永輝、Hassan Elalaf、渡辺真、玉置さくら、日根野翔、松永一仁、Knut Woltjen,　岡本健、松田秀一、戸口田淳也
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] 葉系幹細胞の分化及び形質転換に対するD-2-HG産生型変異IDH1の作用2016
- Author(s)
  鎌倉武史、金永輝、渡辺真、松永一仁、玉置さくら、岡本健史、吉富啓之、戸口田淳也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] Mutant IDH1 dysregulates the differentiation of mesenchymal stem cells in association with gene-specific histone modifications to cartilage- and bone-related genes.2016
- Author(s)
  Jin, Y., Watanabe, M., Tamaki, S., Okamoto, T., and Toguchida, J. Mutant IDH1
- Organizer
  CTOS 21th Annual Meeting
- Place of Presentation
  Lisbon（Portugal）
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] D-2-HG産生を伴うIDH1/2変異が及ぼす骨・軟骨分化への影響2016
- Author(s)
  鎌倉武史、金永輝、渡辺真、岡本健史、吉富啓之、戸口田淳也
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] EXPLORATION OF CANDIDATE GENES TO INDUCE CARTILAGE TUMORS WITH MUTANT IDH1 GENE USING IPSC2016
- Author(s)
  Kamakura, T., Jin, Y., Matsunaga, K., Watanabe, M., Tamaki, S., Okamoto, T., Yoshitomi, H., Toguchida, J
- Organizer
  CTOS 2016 Annual Meeting
- Place of Presentation
  Lisbon（Portugal）
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] 間葉系幹細胞の骨分化能における変異型IDH1の影響2015
- Author(s)
  金永輝、Hassan Elalaf、渡辺真、玉置さくら、日根野翔、松永一仁、Knut Woltjen、岡本健、松田秀一、戸口田淳也
- Organizer
  第48回日本整形外科学会骨軟部腫瘍学術集会
- Place of Presentation
  かがわ国際会議場（香川県高松市）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] SS18-SSX, the oncogenic fusion protein in synvival sarcoma, is a cellular context-dependent epigenetic modifier2015
- Author(s)
  Tamaki S, Fukuta M, Sekiguchi K, Hayakawa K, Jin Y, Hineno S, Okamoto T, Watanbe M, Woltjen K, Ikeya M, Kato T, Toguchida J
- Organizer
  第20回CTOS
- Place of Presentation
  Salt Lake City（USA）
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] Mutant IDH1 dysregulates the differentiation of mesenchymal stem cells in association with gene-specific histone modifications to cartilage- and bone-related genes2015
- Author(s)
  金永輝
- Organizer
  第39回近畿肉腫研究会
- Place of Presentation
  メルパルク京都（京都府京都市）
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PROJECT-25670642
[Presentation] 間葉系幹細胞の骨軟骨分化能における変異型IDH1の影響2015
- Author(s)
  岡本健、金永輝、玉置さくら、松田秀一、戸口田淳也
- Organizer
  第53回日本癌治療学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] Mutant IDH1 desregulates the differentiation property of human mesenchymal stem cells through gene-specific epigenetic modification2015
- Author(s)
  Toguchida J, Jin Y, Watanabe M, Okamoto T
- Organizer
  第20回CTOS
- Place of Presentation
  Salt Lake City（USA）
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] 変異型IDH1は骨・軟骨関連遺伝子のヒストンを遺伝子特異的に修飾し、間葉系幹細胞の分化能を脱制御する2015
- Author(s)
  金永輝、Hassan Elalaf、渡辺真、玉置さくら、日根野翔、松永一仁、Knut Woltjen、岡本健、松田秀一、戸口田淳也
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15H04956
[Presentation] Mutant IDH promotes chondrogenic, but impairs osteogenic differentiation of human mesenchymal stem cells through epigenetic modulation2014
- Author(s)
  Youghui Jin, Hassan Elalaf, Makoto Watanabe, Kazuhito Matsunaga, Tomohisa Kato, Takeshi Okamoto, Shuichi Matsuda, Junya Toguchida
- Organizer
  第４７回日本整形外科学会　骨・軟部腫瘍学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-07-17
- Data Source
  KAKENHI-PROJECT-25670642
[Presentation] Mutation spectrum of IDH genes in Japanese cartilagenous tumors
- Author(s)
  Yonghui Jin
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25670642

1. TOGUCHIDA Junya (40273502)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. Yoshitomi Hiroyuki (50402920)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
3. Ikeya Makoto (20442923)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. OKAMOTO Takeshi (30414113)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. SHIMAZAKI Takeo (50377420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Watanabe Akira (60506765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. SAKURAI Hidetoshi (80528745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAWAMOTO Hiroshi (00343228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MASUDA Kyoko (40565777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 齊藤博英 (20423014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 池川雅哉 (60381943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 戸田口淳也

# of Collaborated Projects: 0 results

# of Collaborated Products: 44 results

Jin Yonghui 金 永輝

JIN Younghui 金 永輝

Research Projects

Research Products

Co-Researchers

Spatial trans-omics analysis of heterotopic ossification process and disease applicationPrincipal Investigator

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Elucidation of mechanism underlying the chondrogenesis-specific translational regulationPrincipal Investigator

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Mechanism analysis of heterotopic ossification formation in Fibrodysplasia Ossificans Progressiva (FOP)Principal Investigator

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Comprehensive understanding of spatio-temporal effects of mutant IDH1 during the development of cartilage forming tumors

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Pathogenesis elucidation of seronegative spondyloarthritis using patient-derived iPSCs

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Functional analyses of mutant NLRP3 on the growth and differentiation of growth plate chondrocytes

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Investigation of functional roles of mutant IDH as specific mutations in cartilage-forming tumors and its application for the development of treatment

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Derivation of human PSC-derived mesodermal cells

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The research on the contribution of mutant IDH gene to the formation of cartilagenous tumors

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[Journal Article] Oxidative phosphorylation is a pivotal therapeutic target of fibrodysplasia ossificans progressiva2024

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[Journal Article] 3D osteogenic differentiation of human iPSCs reveals the role of TGFβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes2023

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[Journal Article] Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human iPSC-Derived Chondrocytes2023

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[Journal Article] Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs2022

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[Journal Article] Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR12020

Jin Yonghui 金永輝

JIN Younghui 金永輝