Takuya Komura 小村卓也

Researcher Number	90623322
External Links
Affiliation (Current)	2023: 独立行政法人国立病院機構(金沢医療センター臨床研究部), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2019 – 2020: 独立行政法人国立病院機構(金沢医療センター臨床研究部), その他部局等, 研究員 2015 – 2018: 金沢大学, 医学系, 協力研究員
Review Section/Research Field	Principal Investigator Epidemiology and preventive medicine / Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 免疫状態 / 糖尿病 / 易発がん / 担癌状態 / 耐糖能異常 / マクロファージ / NASHマウスモデル / 膵臓癌 / マウスモデル / 免疫療法

Development of novel immunotherapy by elucidation of host immune response in pancreatic adenocarcinoma of mouse modelPrincipal Investigator
- Principal Investigator
  
  Komura Takuya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kanazawa Medical Center
  Kanazawa University
Elucidation of immune condition in diabetic patients induced carcinogenic susceptibilityPrincipal Investigator
- Principal Investigator
  
  Takuya Komura
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Epidemiology and preventive medicine
  Gastroenterology
- Research Institution
  Kanazawa University

All 2020 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis2020
- Author(s)
  Ho Tuyen Thuy Bich、Nasti Alessandro、Seki Akihiro、Komura Takuya、Inui Hiiro、Kozaka Takashi、Kitamura Yoji、Shiba Kazuhiro、Yamashita Taro、Yamashita Tatsuya、Mizukoshi Eishiro、Kawaguchi Kazunori、Wada Takashi、Honda Masao、Kaneko Shuichi、Sakai Yoshio
- Journal Title
  
  J Immunother Cancer
  
  Volume: 8
- DOI
  10.1136/jitc-2020-001367
- NAID
  120007185659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08102, KAKENHI-PROJECT-20K17017, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-18K07935, KAKENHI-PROJECT-19K23983
[Journal Article] Inflammatory features of pancreatic cancer highlighted by monocytes/macrophages and CD4+ T cells with clinical impact.2018
- Author(s)
  Komura T, Sakai Y, Harada K, Kawaguchi K, Takabatake H, Kitagawa H, Wada T, Honda M, Ohta T, Nakanuma Y, Kaneko S.
- Journal Title
  
  Cancer Science
  
  Volume: 106(6) Pages: 672-686
- DOI
  10.1111/cas.12663
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460416, KAKENHI-PROJECT-26460995, KAKENHI-PROJECT-15K21022, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378, KAKENHI-PROJECT-26462057
[Presentation] 膵臓癌マウスモデルにおけるGemcitabine治療が引き起こす宿主免疫応答の変化2018
- Author(s)
  小村卓也、酒井佳夫、高畠央、吉田佳子、奥薗舞、ナスティ・アレッサンドロ、山田長司、金子周一
- Organizer
  日本膵臓学会
- Data Source
  KAKENHI-PROJECT-18K07935
[Presentation] 膵臓癌マウスモデルにおける宿主免疫応答状態の解明2017
- Author(s)
  小村卓也、酒井佳夫、高畠央、金子周一
- Organizer
  日本膵臓学会
- Data Source
  KAKENHI-PROJECT-15K21022
[Presentation] Inflammatory conditions of colorectal cancer inflammation are featured by monocytes/macrophages lineage and CD4+ T cells associated with their humoral mediators in blood.2016
- Author(s)
  Takuya Komura, Yoshio Sakai, Hisashi Takabatake, Masaki Miyazawa1, Akihiro Seki, Hatsune Mochida, Masao Honda, Takashi Wada, Shuichi Kaneko
- Organizer
  第10回日米癌合同会議
- Place of Presentation
  マウイ島（アメリカ）
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21022
[Presentation] 膵臓癌における宿主免疫応答状態の解明2016
- Author(s)
  小村卓也
- Organizer
  JDDW
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K21022
[Presentation] The　features of host immune response in patients with pancreatic ductal adenocarcinoma2016
- Author(s)
  Takuya Komura
- Organizer
  UEGW
- Place of Presentation
  Austria (Wienna)
- Year and Date
  2016-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21022
[Presentation] The immune features in blood of patients with pancreatic ductal adenocarcinoma2016
- Author(s)
  Takuya Komura
- Organizer
  国際膵臓学会/日本膵臓学会　共催
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21022
[Presentation] Inflammatory Features of Pancreatic Cancer Highlighted by Monocytes/Macrophages and CD4+ T cells with Clinical Impact2015
- Author(s)
  Takuya Komura, Yoshio Sakai, Takashi Wada, Shuichi Kaneko
- Organizer
  日本免疫学会
- Place of Presentation
  北海道（札幌）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K21022
[Presentation] The high frequency of PD-1 in peripheral CD4+ T cells of Pancreatic Ductal Adenocarcinoma is potentially useful for development of the novel diagnostic methods and prediction of chemotherapy responsiveness.2015
- Author(s)
  Takuya Komura, Yoshio Sakai, Takashi Wada, Shuichi Kaneko
- Organizer
  2015　UEGW
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21022

1. Sakai Yoshio (80401925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. KITAMURA Yoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 関晃裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 原田憲一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 北川裕久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takuya Komura 小村 卓也

Research Projects

Research Products

Co-Researchers

Development of novel immunotherapy by elucidation of host immune response in pancreatic adenocarcinoma of mouse modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of immune condition in diabetic patients induced carcinogenic susceptibilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Inflammatory features of pancreatic cancer highlighted by monocytes/macrophages and CD4+ T cells with clinical impact.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 膵臓癌マウスモデルにおけるGemcitabine治療が引き起こす宿主免疫応答の変化2018

Author(s)

Organizer

Data Source

[Presentation] 膵臓癌マウスモデルにおける宿主免疫応答状態の解明2017

Author(s)

Organizer

Data Source

[Presentation] Inflammatory conditions of colorectal cancer inflammation are featured by monocytes/macrophages lineage and CD4+ T cells associated with their humoral mediators in blood.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 膵臓癌における宿主免疫応答状態の解明2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The features of host immune response in patients with pancreatic ductal adenocarcinoma2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The immune features in blood of patients with pancreatic ductal adenocarcinoma2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Inflammatory Features of Pancreatic Cancer Highlighted by Monocytes/Macrophages and CD4+ T cells with Clinical Impact2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The high frequency of PD-1 in peripheral CD4+ T cells of Pancreatic Ductal Adenocarcinoma is potentially useful for development of the novel diagnostic methods and prediction of chemotherapy responsiveness.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Takuya Komura 小村卓也

[Presentation] The　features of host immune response in patients with pancreatic ductal adenocarcinoma2016