Takaguri Akira 高栗郷

… Alternative Names

TAKAGURI Akira 高栗郷

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Researcher Number	90623710
Other IDs
Affiliation (Current)	2025: 北海道科学大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 北海道科学大学, 薬学部, 准教授 2014 – 2017: 北海道薬科大学, 薬学部, 准教授 2013: 北海道薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Basic Section 47040:Pharmacology-related Except Principal Investigator Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator インスリン抵抗性 / Insulin signaling / ADAM17 / プラーク破綻 / 血管平滑筋特異的ノックアウトマウス / Hippo経路 / 血管平滑筋細胞特異的YAP1ノックアウトマウス / 腹部大動脈瘤 / 内膜肥厚 / 炎症 … More / YAP1 / 血管平滑筋細胞 / 動脈硬化 / Yeast two-hybrid / ER stress / ERK / AMAM17 / IRS-1 / AngiotensinII / skeletal muscle cells / insulin resistance / 小胞体ストレス / 骨格筋細胞 / GIPC1 / エンドセリン-1 / インターロイキン-1 / Akt / Interleukin-1 / Skeletal muscle cells / Insulin resistance / Endothelin-1 / Interluekin-1 … More Except Principal Investigator 細胞死 / フェロトーシス / 炎症 / エラスチン / YAP1 / 血管平滑筋細胞 / 腹部大動脈瘤 Less

The physiological role of YAP1 Hippo pathway effector YAP1 in abdominal aortic aneurysm formation and rupture
- Principal Investigator
  
  Satoh Kumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Hokkaido University of Science
The role of Hippo pathway transcriptional co-activator, YAP1 in the pathogenesis of AtherosclerosisPrincipal Investigator
- Principal Investigator
  
  TAKAGURI AKIRA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Hokkaido University of Science
Role of ADAM17 for glucose metabolism in skeletal muscle cellsPrincipal Investigator
- Principal Investigator
  
  Takaguri Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Hokkaido Pharmaceutical University School of Pharmacy
Study on the role of metalloprotease ADAM in insulin signalingPrincipal Investigator
- Principal Investigator
  
  TAKAGURI Akira
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Hokkaido Pharmaceutical University School of Pharmacy

All 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Norepinephrine transporter expressed on mammary epithelial cells incorporates norepinephrine in milk into the cells2021
- Author(s)
  Chiba T., Takaguri A., Maeda T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 545 Pages: 1-7
- DOI
  10.1016/j.bbrc.2021.01.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07227, KAKENHI-PROJECT-18K06703
[Journal Article] Metabolomic analysis of SMP30/GNL knockout mice treated with fermented vegetable and fruit extract (OM-X?)2020
- Author(s)
  Wakame Koji、Takahata Muneaki、Miyake Yasuyoshi、Yasuda Eri、Shimomiya Yoshie、Nakata Akifumi、Sato Keisuke、Mihara Yoshihiro、Takaguri Akira、Komatsu Ken-ichi
- Journal Title
  
  Functional Foods in Health and Disease
  
  Volume: 10 Issue: 3 Pages: 95-95
- DOI
  10.31989/ffhd.v10i3.674
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06703
[Journal Article] The role of circadian clock gene BMAL1 in vascular proliferation2020
- Author(s)
  Takaguri Akira、Sasano Jun、Akihiro Oomiya、Satoh Kumi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 872 Pages: 172924-172924
- DOI
  10.1016/j.ejphar.2020.172924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06703
[Journal Article] Involvement of Yes‐associated protein 1 (YAP1) in doxorubicin‐induced cytotoxicity in H9c2 cardiac cells2020
- Author(s)
  Takaguri Akira、Akihiro Ohmiya、Sasano Jun、Satoh Kumi
- Journal Title
  
  Cell Biology International
  
  Volume: 44 Issue: 3 Pages: 873-881
- DOI
  10.1002/cbin.11285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06703
[Journal Article] Global Liver Gene Expression Analysis on a Murine Hepatic Steatosis Model Treated with Mulberry (Morus alba L.) Leaf Powder2018
- Author(s)
  UCHIYAMA HIRONOBU、KOMATSU KEN-ICHI、NAKATA AKIFUMI、SATO KEISUKE、MIHARA YOSHIHIRO、TAKAGURI AKIRA、NAGASHIMA TAKAYUKI、WAKAME KOJI
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 7 Pages: 4305-4311
- DOI
  10.21873/anticanres.12729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06703
[Journal Article] Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction2018
- Author(s)
  Takaguri Akira
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 11 Pages: 1329-1334
- DOI
  10.1248/yakushi.18-00116
- NAID
  130007503045
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-11-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-18K06703
[Journal Article] The protective role of YAP1 on ER stress-induced cell death in vascular smooth muscle cells2017
- Author(s)
  Takaguri Akira、Kubo Takashi、Mori Masaya、Satoh Kumi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 815 Pages: 470-477
- DOI
  10.1016/j.ejphar.2017.09.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18876
[Journal Article] Transcriptome Analysis of Skin from SMP30/GNL Knockout Mice Reveals the Effect of Ascorbic Acid Deficiency on Skin and Hair2017
- Author(s)
  Wakame koji、Komatsu Ken-ichi、Nakata Alifumi、Sato Keisuke、Takaguri Akira、Masutomi Hirofumi、Nagashima Takayuki、Uchiyama Hironobu
- Journal Title
  
  In vivo
  
  Volume: 31 Pages: 599-607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18876
[Journal Article] AMPK activation by prolonged stimulation with interleukin-1β contributes to the promotion of GLUT4 translocation in skeletal muscle cells2016
- Author(s)
  Takaguri A, Inoue S, Kubo T, Satoh K.
- Journal Title
  
  Cell Biol Int.
  
  Volume: 40 Pages: 1204-1211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18876
[Presentation] 血管リモデリングにおける時計遺伝子Bmalの役割解明2019
- Author(s)
  高栗郷、笹野潤、近江谷允明、久保貴司、佐藤久美
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06703
[Presentation] 血管平滑筋細胞の増殖における時計遺伝子BMAL1の役割解明2019
- Author(s)
  高栗郷、笹野潤、近江谷允明、佐藤久美
- Organizer
  第70回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-18K06703
[Presentation] 血管平滑筋細胞における細胞増殖と細胞死に及ぼすYAP1の機能的役割2018
- Author(s)
  久保貴司、高栗郷、佐藤久美
- Organizer
  第91回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06703
[Presentation] 時計遺伝子Bmal1の内膜肥厚形成制御に関する検討2018
- Author(s)
  久保貴司、高栗郷、佐藤久美
- Organizer
  日本薬学会北海道支部第145回例会
- Data Source
  KAKENHI-PROJECT-18K06703
[Presentation] ERストレス誘導性細胞死に対するYAP1の保護的役割2017
- Author(s)
  久保貴司、高栗郷、佐藤久美
- Organizer
  第68回薬理学会北部会
- Data Source
  KAKENHI-PROJECT-15K18876
[Presentation] The role of YAP1 on ER stress-induced cell death in vascular smooth muscle cells2017
- Author(s)
  Takashi Kubo, Akira Takaguri, Kumi Satoh
- Organizer
  第90回日本薬理学会
- Data Source
  KAKENHI-PROJECT-15K18876
[Presentation] インスリンシグナル伝達に対するサイトカインの多様な作用2017
- Author(s)
  高栗郷
- Organizer
  第６４回北海道薬学大会
- Data Source
  KAKENHI-PROJECT-15K18876
[Presentation] 血管平滑筋細胞におけるERストレス誘導性細胞死に対するYAP1の役割2017
- Author(s)
  高栗郷、久保貴司、佐藤久美
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-15K18876
[Presentation] Interleukin-1の長時間処理によるGLUT4トランスロケーションにおけるAMPKの関与2016
- Author(s)
  高栗郷、井上沙綾、久保貴司、佐藤久美
- Organizer
  第67回日本薬理学会北部会
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-15K18876
[Presentation] Effect of prolonged stimulation of interleukin-1 on insulin signal transduction in L6 skeletal muscle cells2016
- Author(s)
  高栗郷,井上沙綾,今井伸一, 佐藤久美
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K18876
[Presentation] L6 骨格筋細胞のインスリンシグナル伝達におけるADAM17の役割2015
- Author(s)
  高栗郷、佐藤久美
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-08
- Data Source
  KAKENHI-PROJECT-25860064
[Presentation] インスリンシグナル伝達に対する ADAM17の機能的役割解明2014
- Author(s)
  高栗郷、佐藤久美
- Organizer
  第65回日本薬理学会北部会
- Place of Presentation
  福島
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25860064
[Presentation] A DISINTEGRIN AND METALLOPROTEASE 17, A POTENTIAL MEDIATOR OF INTERLEUKIN-1Α DEPENDENT INSULIN RESISTANCE IN L6 RAT SKELETAL MUSCLE CELLS2014
- Author(s)
  Akira Takaguri, Kumi Satoh
- Organizer
  10th IDF-WPR and 6th AASD Scientific Meeting 2014
- Place of Presentation
  シンガポール
- Year and Date
  2014-11-22
- Data Source
  KAKENHI-PROJECT-25860064
[Presentation] サイトカインによるADAM発現メカニズムの解明2014
- Author(s)
  倉田舞、高栗郷、佐藤久美
- Organizer
  北海道薬学大会
- Place of Presentation
  札幌
- Year and Date
  2014-05-25
- Data Source
  KAKENHI-PROJECT-25860064
[Presentation] サイトカインによるADAM17の発現調節メカニズムの解明
- Author(s)
  倉田舞、高栗郷、佐藤久美
- Organizer
  第61回北海道薬学大会
- Place of Presentation
  白石コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25860064

1. Satoh Kumi (00235334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 前田智司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 千葉健史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takaguri Akira 高栗 郷

TAKAGURI Akira 高栗 郷

Research Projects

Research Products

Co-Researchers

The physiological role of YAP1 Hippo pathway effector YAP1 in abdominal aortic aneurysm formation and rupture

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of Hippo pathway transcriptional co-activator, YAP1 in the pathogenesis of AtherosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of ADAM17 for glucose metabolism in skeletal muscle cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the role of metalloprotease ADAM in insulin signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Norepinephrine transporter expressed on mammary epithelial cells incorporates norepinephrine in milk into the cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolomic analysis of SMP30/GNL knockout mice treated with fermented vegetable and fruit extract (OM-X?)2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of circadian clock gene BMAL1 in vascular proliferation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of Yes‐associated protein 1 (YAP1) in doxorubicin‐induced cytotoxicity in H9c2 cardiac cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global Liver Gene Expression Analysis on a Murine Hepatic Steatosis Model Treated with Mulberry (Morus alba L.) Leaf Powder2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] The protective role of YAP1 on ER stress-induced cell death in vascular smooth muscle cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptome Analysis of Skin from SMP30/GNL Knockout Mice Reveals the Effect of Ascorbic Acid Deficiency on Skin and Hair2017

Author(s)

Journal Title

Data Source

[Journal Article] AMPK activation by prolonged stimulation with interleukin-1β contributes to the promotion of GLUT4 translocation in skeletal muscle cells2016

Author(s)

Journal Title

Data Source

[Presentation] 血管リモデリングにおける時計遺伝子Bmalの役割解明2019

Author(s)

Organizer

Data Source

Takaguri Akira 高栗郷

TAKAGURI Akira 高栗郷