Murata Akihiko 村田暁彦

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MURATA Akihiko 村田暁彦

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Researcher Number	90624221
Other IDs
Affiliation (Current)	2025: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤) 2013 – 2024: 鳥取大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Experimental pathology Except Principal Investigator Broad Section H
Keywords	Principal Investigator 組織常在性記憶T細胞 / 接触性皮膚炎 / 皮膚局所の免疫記憶 / アトピー性皮膚炎 / マクロファージ / アレルギー性皮膚疾患 / 接触過敏症 / 表皮ｇamma-delta T細胞 / マスト細胞 / 局所的な免疫記憶 … More / ニッチ / 遅延型過敏症 / 生存ニッチ / 常在性記憶T細胞 / 常在性記憶ヘルパーT細胞 / 皮膚マクロファージ / 局所免疫記憶 / 皮膚常在性記憶ヘルパーT細胞 / ヘルパーT細胞 / gamma-delta T細胞 / CD8+ T細胞 / CD4+ T細胞 / 皮膚炎 / 炎症 / Jagged / Delta-like / 細胞接着 / 炎症性疾患 / 接着分子 / Notch … More Except Principal Investigator ノックアウトマウス / 非アルコール性脂肪性肝疾患 / 自己免疫疾患 / RNA安定性 / T細胞 Less

An integrated understanding of immunity and metabolism revealed through Regnase research
- Principal Investigator
  
  審良静男
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section H
- Research Institution
  The University of Osaka
Regulation of local skin immune memory by tissue myeloid cell remodelingPrincipal Investigator
- Principal Investigator
  
  村田暁彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tottori University
Maintenance of skin resident memory helper T cell survival by macrophagesPrincipal Investigator
- Principal Investigator
  
  MURATA Akihiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tottori University
How do tissue resident memory T cells induce the local recurrence of atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  MURATA Akihiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tottori University
Why does atopic dermatitis often relapse in the same skin region?Principal Investigator
- Principal Investigator
  
  Murata Akihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tottori University
Regulation of chronic inflammatory disorders by Notch as a cell adhesion moleculePrincipal Investigator
- Principal Investigator
  
  MURATA Akihiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tottori University

All 2024 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] 常在生記憶ヘルパーT細胞が担う皮膚の局所的な長期免疫記憶2021
- Author(s)
  村田暁彦
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 75 Pages: 292-298
- Data Source
  KAKENHI-PROJECT-18K08297
[Journal Article] Multiple developmental pathways lead to the generation of CD4 T-cell memory2020
- Author(s)
  Hojyo Shintaro、Tumes Damon、Murata Akihiko、Tokoyoda Koji
- Journal Title
  
  International Immunology
  
  Volume: 32 Issue: 9 Pages: 589-595
- DOI
  10.1093/intimm/dxaa051
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22764, KAKENHI-PROJECT-18K08297
[Journal Article] Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells2020
- Author(s)
  Iida Yuichi、Yoshikawa Rintaro、Murata Akihiko、Kotani Hitoshi、Kazuki Yasuhiro、Oshimura Mitsuo、Matsuzaki Yumi、Harada Mamoru
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 8 Issue: 2 Pages: e000582-e000582
- DOI
  10.1136/jitc-2020-000582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393, KAKENHI-PROJECT-18K08297, KAKENHI-PROJECT-19K16713
[Journal Article] Overexpression of miR-669m inhibits erythroblast differentiation2020
- Author(s)
  Kotaki R., et.al. Kawashima M, Yamaguchi A, Suzuki N, Koyama-Nasu R, Ogiya D, Okuyama K, Yamamoto Y, Takamatsu M, Kurosaki N, Ando K, Murata A, Ohtsuka M, Nakagawa S, Katagiri K, Kotani A.
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Issue: 1 Pages: 13554-13554
- DOI
  10.1038/s41598-020-70442-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07612, KAKENHI-PROJECT-20K07459, KAKENHI-PROJECT-20K21550, KAKENHI-PROJECT-20H03716, KAKENHI-PROJECT-18K08297
[Journal Article] CD4+-resident memory T cells mediate long-term local skin immune memory of contact hypersensitivity in BALB/c mice2020
- Author(s)
  Akihiko Murata, Shin-Ichi Hayashi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: in press Pages: 775-775
- DOI
  10.3389/fimmu.2020.00775
- NAID
  120007170662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08297
[Journal Article] Notchによるマスト細胞の接着2019
- Author(s)
  村田暁彦，林眞一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 71 Pages: 576-582
- Data Source
  KAKENHI-PROJECT-18K08297
[Journal Article] Kit-independent mast cell adhesion mediated by Notch2019
- Author(s)
  Akihiko Murata, Mari Hikosaka, Miya Yoshino, Lan Zhou, Shin-Ichi Hayashi
- Journal Title
  
  International Immunology
  
  Volume: 31 Issue: 2 Pages: 69-79
- DOI
  10.1093/intimm/dxy067
- NAID
  120007170663
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08297, KAKENHI-PROJECT-19K07481
[Journal Article] 接触過敏症における皮膚局所の免疫記憶2018
- Author(s)
  村田暁彦, 林眞一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 70 Pages: 367-372
- Data Source
  KAKENHI-PROJECT-18K08297
[Journal Article] Correlation between cell aggregation and antibody production in IgE-producing plasma cells.2017
- Author(s)
  Hikosaka, M., Murata, A., Yoshino, M., and Hayashi, S.I.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: in press Pages: 224-231
- DOI
  10.1016/j.bbrep.2017.04.007
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460488, KAKENHI-PROJECT-15K19076
[Journal Article] Notch-mediated cell adhesion2016
- Author(s)
  Akihiko Murata, Shin-Ichi Hayashi
- Journal Title
  
  Biology(Basel)
  
  Volume: 5 Issue: 1 Pages: 5-5
- DOI
  10.3390/biology5010005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19076, KAKENHI-PROJECT-26460488
[Journal Article] 抗原特異的細胞の凝集によるＩｇＥ産生制御2016
- Author(s)
  彦坂茉里、村田暁彦、吉野三也、林眞一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 65 Pages: 334-339
- Data Source
  KAKENHI-PROJECT-15K19076
[Journal Article] An evolutionary-conserved function of mammalian notch family members as cell adhesion molecules.2014
- Author(s)
  Akihiko Murata, Miya Yoshino, Mari Hikosaka, Kazuki Okuyama, Lan Zhou, Seiji Sakano, Hideo Yagita, Shin-Ichi Hayashi
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 9 Pages: e108535-e108535
- DOI
  10.1371/journal.pone.0108535
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860295, KAKENHI-PROJECT-26460488, KAKENHI-PROJECT-26830115
[Journal Article] Dual system for the transport of self-antigens from the skin2013
- Author(s)
  Miya Yoshino, Akihiko Murata, Yuhki Shimoda, Mari Hikosaka, Shin-Ichi Hayashi
- Journal Title
  
  Current Research in Immunology
  
  Volume: 7 Pages: 1-12
- Data Source
  KAKENHI-PROJECT-25860295
[Presentation] Macrophages function as survival niches for CD4+ skin-resident memory T cells2024
- Author(s)
  Akihiko Murata, Koji Tokoyoda
- Organizer
  第52回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08325
[Presentation] In vivo predominant immunoglobulin secretion in the bone marrow IgG-secreting plasma cells2022
- Author(s)
  Shogo Tsuda, Harumi Sasaki, Akihiko Murata, Koji Tokoyoda
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08325
[Presentation] CD4+ skin-resident memory T cells persist in CD68+ cellular niches2022
- Author(s)
  Akihiko Murata, Momoka Wakazuki, Koji Tokoyoda
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08325
[Presentation] Isotype-specific metabolic requirements for survival of bone marrow plasma cells2021
- Author(s)
  Akihiko Murata, Harumi Sasaki, Koji Tokoyoda
- Organizer
  第50回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08325
[Presentation] CD4+ and CD8+ resident memory T cells redundantly mediate local skin memory response in contact dermatitis.2019
- Author(s)
  Murata A, Yoshino M, Hayashi SI
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K08297
[Presentation] Local deliver of CCL19-expressing mesenchymal stromal cells augments the therapeutic efficacy by anti-PD-L1 blockade antibody via promoting infiltration of immune cells.2019
- Author(s)
  Iida Y, Yoshikawa R, Murata A, Kotani H, Harada M
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K08297
[Presentation] Influence of immune activation on the transport of skin self-antigens to regional lymph nodes.2019
- Author(s)
  Yoshino M, Murata A, Hayashi SI
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K08297
[Presentation] Local skin memory response is mediated by tissue resident memory T cells2018
- Author(s)
  Akihiko Murata, Miya Yoshino, Shin-Ichi Hayashi
- Organizer
  第47回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K08297
[Presentation] Distinct effect of LPS stimulation on TLR3 expression in macrophage subsets2018
- Author(s)
  Kazune Tanigawa, Akihito Murata, Miya Yoshino, Shin-Ichi Hayashi
- Organizer
  第47回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K08297
[Presentation] Local delivery of CCL19-expressing mesenchymal stromal cells suppresses the tumor growth via promoting infiltration of immune cells2018
- Author(s)
  Yuichi Iida, Rintaro Yoshikawa, Akihiko Murata, Yumi Matsuzaki, Mamoru Harada
- Organizer
  第47回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K08297
[Presentation] Analysis of the transport of self-antigens from the skin to regional LNs under inflammatory conditions2018
- Author(s)
  Miya Yoshino, Kazune Tanigawa, Akihiko Murata, Shin-Ichi Hayashi
- Organizer
  第47回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K08297
[Presentation] Local skin memory response in contact dermatitis involves tissue resident memory T cells2017
- Author(s)
  Akihiko Murata, Miya Yoshino, Shin-Ichi Hayashi
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Measurement of the transport of skin self-antigens under inflammatory conditions2017
- Author(s)
  Miya Yoshino, Kaori Suekane, Ai Suzuki, Naoto Honda, Kazune Tanigawa, Akihiko Murata, Shin-Ichi Hayashi
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Measurement of altered transport of skin self-antigens in the active state2016
- Author(s)
  Miya Yoshino, Akihiko Murata, Mari Hikosaka, Shin-Ichi Hayashi
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県、宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Intensity of local skin memory response varying with the type of locally persisting T cell subsets2016
- Author(s)
  Akihiko Murata
- Organizer
  16th International Congress of Immunology
- Place of Presentation
  Melbourne Convention and Exibition Centre(Melbourne, Australia)
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Enhancement of antibody production in IgE producing cells requires cell aggregation via Fc gamma-receptors2016
- Author(s)
  Mari Hikosaka, Akihiko Murata, Miya Yoshino, Shin-Ichi Hayashi
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県、宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] C57BL/6 mice lack the local skin memory formation by contact dermatitis2016
- Author(s)
  Akihiko Murata, Miya Yoshino, Mari Hikosaka, Shin-Ichi Hayashi
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県、宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Analysis of the transport of skin self-antigens in Pynod-Ccr7-double knockout mice2015
- Author(s)
  Miya Yoshino, Akihiko Murata, Mari Hikosaka, Shin-Ichi Hayashi
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道、札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Mast cells are dispensable for the local skin memory response2015
- Author(s)
  Akihiko Murata, Miya Yoshino, Mari Hikosaka, Shin-Ichi Hayashi
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道、札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Antigen-mediated cell aggregation in IgE-producing cells2015
- Author(s)
  Mari Hikosaka, Akihiko Murata, Yuhki Shimoda, Miya Yoshino, Shin-Ichi Hayashi
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道、札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19076
[Presentation] Analysis of cells transporting skin self-antigens to regional lymph nodes under CCR7-deficient conditions2013
- Author(s)
  Miya Yoshino, Akihiko Murata, Yuhki Shimoda, Mari Hikosaka, Shin-Ichi Hayashi
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  千葉、幕張
- Data Source
  KAKENHI-PROJECT-25860295
[Presentation] Up-regulation of Aicda gene expression in IgE producing hybridomas: a model of class switch recommbination in plasma cells2013
- Author(s)
  Mari Hikosaka, Akihiko Murata, Yuhki Shimoda, Miya Yoshino, Shin-Ichi Hayashi
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  千葉、幕張
- Data Source
  KAKENHI-PROJECT-25860295
[Presentation] Cell adhesion mediated by Notch ligands: An implication for mast cell accumulation in chronic inflammation2013
- Author(s)
  Akihiko Murata, Miya Yoshino, Yuhki Shimoda, Mari Hikosaka, Hideo Yagita, Shin-Ichi Hayashi
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  千葉、幕張
- Data Source
  KAKENHI-PROJECT-25860295
[Presentation] Putative regulation of IgE production by antigen-specific cell aggregation.
- Author(s)
  Mari Hikosaka, Akihiko Murata, Yuhki Shimoda, Miya Yoshino, Shin-Ichi Hayashi
- Organizer
  第43回日本免疫学会・学術集会
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860295
[Presentation] Local increase of mast cells sustains after resolution of chronic contact dermatitis.
- Author(s)
  Akihiko Murata, Miya Yoshino, Yuhki Shimoda, Mari Hikosaka, Shin-Ichi Hayashi
- Organizer
  第43回日本免疫学会・学術集会
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860295
[Presentation] Functional and comprehensive investigation of microRNA targeting Notch receptors.
- Author(s)
  Kazuki Okuyama, Katsuto Hozumi, Akihiko Murata, Kiyoshi Ando, Ai Kotani
- Organizer
  第43回日本免疫学会・学術集会
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860295
[Presentation] Migration of skin antigen-transporting cells in PYNOD-deficient mice.
- Author(s)
  Miya Yoshino, Ryu Imamura, Akihiko Murata, Yuhki Shimoda, Mari Hikosaka, Takashi Suda, Shin-Ichi Hayashi
- Organizer
  第43回日本免疫学会・学術集会
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860295

1. 審良静男 (50192919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 前田和彦 (20332869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KOTANI Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 常世田好司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 片桐晃子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 林眞一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murata Akihiko 村田 暁彦

MURATA Akihiko 村田 暁彦

Research Projects

Research Products

Co-Researchers

An integrated understanding of immunity and metabolism revealed through Regnase research

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of local skin immune memory by tissue myeloid cell remodelingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Maintenance of skin resident memory helper T cell survival by macrophagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

How do tissue resident memory T cells induce the local recurrence of atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Why does atopic dermatitis often relapse in the same skin region?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of chronic inflammatory disorders by Notch as a cell adhesion moleculePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 常在生記憶ヘルパーT細胞が担う皮膚の局所的な長期免疫記憶2021

Author(s)

Journal Title

Data Source

[Journal Article] Multiple developmental pathways lead to the generation of CD4 T-cell memory2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overexpression of miR-669m inhibits erythroblast differentiation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD4+-resident memory T cells mediate long-term local skin immune memory of contact hypersensitivity in BALB/c mice2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Notchによるマスト細胞の接着2019

Author(s)

Journal Title

Data Source

[Journal Article] Kit-independent mast cell adhesion mediated by Notch2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] 接触過敏症における皮膚局所の免疫記憶2018

Author(s)

Journal Title

Data Source

Murata Akihiko 村田暁彦

MURATA Akihiko 村田暁彦