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yoneyama hiroki  米山 弘樹

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YONEYAMA Hiroki  米山 弘樹

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Researcher Number 90627001
Other IDs
Affiliation (Current) 2025: 大阪医科薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2017: 大阪薬科大学, 薬学部, 助教
Review Section/Research Field
Except Principal Investigator
Physical pharmacy
Keywords
Except Principal Investigator
薬物耐性 / 細胞内取込 / 核酸 / 金属錯体 / 白金制がん剤 / 細胞内蓄積 / 抗腫瘍効果 / 大腸がん / オキサリプラチン / 白金製剤 … More / 難治性がん / 創薬 / DDS / 制がん剤 / 白金錯体 Less
  • Research Projects

    (1 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (5 People)
  •  Drug discovery research based on dinuclear platinum complexes with markedly high antitumor activity

    • Principal Investigator
      Komeda Seiji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Suzuka University of Medical Science

All 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer2017

    • Author(s)
      S. Komeda, H. Yoneyama, M. Uemura, A. Muramatsu, N. Okamoto,
    • Journal Title

      Inorg. Chem.

      Volume: 56 Issue: 2 Pages: 802-811

    • DOI

      10.1021/acs.inorgchem.6b02239

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460160, KAKENHI-PROJECT-15K07905, KAKENHI-PLANNED-25103012
  • [Presentation] メチル基を有するテトラゾラト架橋白金(II)二核錯体のDNAとの相互作用および細胞内取り込みにおけるフッ素導入効果の検討2018

    • Author(s)
      植村雅子,米山弘樹,春沢信哉,米田誠治
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] 顕著な抗腫瘍効果を有する白金(II)二核錯体のユニークな作用機構2017

    • Author(s)
      植村 雅子、米田 誠治、吉川 研一、吉川 祐子、春沢 信哉、米山 弘樹
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台市
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] 制がん白金(II)二核錯体のDNA凝縮能および細胞内取り込みに関する研究2017

    • Author(s)
      植村雅子, 米山弘樹, 岡本直人, 村松 晃, 福田青郎, 小西宏明, 髙木 陽光, 松﨑 健, 春沢信哉, 吉川祐子, 今中忠行, 吉川研一,米田誠治
    • Organizer
      第63回日本薬学会東海支部 総会・大会
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] Structure-activity relationships, DNA compaction efficiencies and intracellular accumulations on anticancer-active tetrazolato-bridged dinuclear platinum(II) complexes2017

    • Author(s)
      Komeda, S.; Uemura, M.; Hiramoto, K.; Yoshikawa, Y.; Yoshikawa, K.; Yoneyama, H.; Harusawa, S.
    • Organizer
      14th International Symposium on Applied Bioinorganic Chemistry
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] DNA interaction and structure-activity telationship of tetrazolato-bridged dinuclear platinum(II) complexes with fluoromethyl group2017

    • Author(s)
      植村雅子,米山弘樹,坂﨑智哉,長江紀樹,小井阪あゆみ,春沢信哉,米田誠治
    • Organizer
      第27回金属の関与する生体関連反応シンポジウム
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] DNA interactions and structure-activity relationship of tetrazolato-bridged dinuclear platinum(II) complexes with methyl and fluoromethyl group2017

    • Author(s)
      Uemura, M.; Yoneyama, H.; Harusawa, S.; Komeda, S.
    • Organizer
      12th International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] 長短鎖アルキル基を導入した制がんテトラゾラト架橋白金(II)二核錯体の細胞 内取込およびDNA凝縮能2016

    • Author(s)
      米田誠治, 植村雅子, 米山弘樹, 岡本直人, 村松 晃, 福田青郎, 小西宏明, 髙木 陽光, 松﨑 健, 春沢信哉, 吉川祐子, 今中忠行, 吉川研一
    • Organizer
      日本薬学会 第136年会 横浜市 年月日201603-201603
    • Place of Presentation
      横浜市
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] Biological efficiency of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with different length of alkyl substituent in relation to the structural effect of DNA2016

    • Author(s)
      Komeda, S.; Uemura, M.; Yoneyama, H.; Muramatsu, A.; Okamoto, N.; Harusawa, S.; Yoshikawa, Y.; Yoshikawa, K.
    • Organizer
      金属の関与する生体関連反応シンポジウム (SRM2016)
    • Place of Presentation
      札幌市
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] Action of novel anticancer-active, dinuclear platinum complexes with ester group on the higher order structure and genomic activity of DNA2015

    • Author(s)
      Shimizu, Y; Yoshikawa, Y; TaTsuchiya, T; Hiroki Yoneyama, H; Harusawa, S; Komeda, S; Imanaka, T; Kenmotsu, T; Yoshikawa, K.
    • Organizer
      第53回生物物理学会日本薬学会
    • Place of Presentation
      金沢市
    • Year and Date
      2015-09-13
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015

    • Author(s)
      Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
    • Organizer
      第25回金属の関与する生体関連反応シンポジウム
    • Place of Presentation
      長崎市
    • Year and Date
      2015-05-30
    • Data Source
      KAKENHI-PROJECT-15K07905
  • [Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015

    • Author(s)
      Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
    • Organizer
      1st International Symposium on Clinical and Experimental Metallodrugs in Medicine: Cancer Chemotherapy
    • Place of Presentation
      米国ハワイ州
    • Year and Date
      2015-12-13
    • Data Source
      KAKENHI-PROJECT-15K07905
  • 1.  Komeda Seiji (60425056)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 2.  HIRAMOTO Keiichi (90251793)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  HARUSAWA Shinya (90167601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 4.  YOSHIKAWA Yuko (80291871)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  植村 雅子 (70511997)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results

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