YONEYAMA Hiroki 米山弘樹

Researcher Number	90627001
Other IDs
Affiliation (Current)	2020: 大阪薬科大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2017: 大阪薬科大学, 薬学部, 助教
Review Section/Research Field	Except Principal Investigator Physical pharmacy
Keywords	Except Principal Investigator 白金錯体 / 制がん剤 / DDS / 創薬 / 難治性がん / 白金製剤 / 白金制がん剤 / 金属錯体 / 核酸 / 大腸がん / 細胞内取込 / 薬物耐性

Drug discovery research based on dinuclear platinum complexes with markedly high antitumor activity
- Principal Investigator
  
  Komeda Seiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Suzuka University of Medical Science

All 2017 2016 2015

All Journal Article Presentation

[Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer Tetrazolato-Bridged Dinuclear Platinum(II) Complexes: Middle-Length Alkyl Substituents Exhibit Minimum Effect2017
- Author(s)
  S. Komeda, H. Yoneyama, M. Uemura, A. Muramatsu, N. Okamoto,
- Journal Title
  
  Inorganic Chemistry
  
  Volume: 56 Pages: 802-811
- DOI
  10.1021/acs.inorgchem.6b02239
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460160, KAKENHI-PROJECT-15K07905, KAKENHI-PLANNED-25103012
[Presentation] 顕著な抗腫瘍効果を有する白金(II)二核錯体のユニークな作用機構2017
- Author(s)
  植村雅子、米田誠治、吉川研一、吉川祐子、春沢信哉、米山弘樹
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 長短鎖アルキル基を導入した制がんテトラゾラト架橋白金(II)二核錯体の細胞内取込およびDNA凝縮能2016
- Author(s)
  米田誠治, 植村雅子, 米山弘樹, 岡本直人, 村松晃, 福田青郎, 小西宏明, 髙木陽光, 松﨑健, 春沢信哉, 吉川祐子, 今中忠行, 吉川研一
- Organizer
  日本薬学会第136年会横浜市年月日201603-201603
- Place of Presentation
  横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Biological efficiency of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with different length of alkyl substituent in relation to the structural effect of DNA2016
- Author(s)
  Komeda, S.; Uemura, M.; Yoneyama, H.; Muramatsu, A.; Okamoto, N.; Harusawa, S.; Yoshikawa, Y.; Yoshikawa, K.
- Organizer
  金属の関与する生体関連反応シンポジウム (SRM2016)
- Place of Presentation
  札幌市
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Action of novel anticancer-active, dinuclear platinum complexes with ester group on the higher order structure and genomic activity of DNA2015
- Author(s)
  Shimizu, Y; Yoshikawa, Y; TaTsuchiya, T; Hiroki Yoneyama, H; Harusawa, S; Komeda, S; Imanaka, T; Kenmotsu, T; Yoshikawa, K.
- Organizer
  第53回生物物理学会日本薬学会
- Place of Presentation
  金沢市
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015
- Author(s)
  Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
- Organizer
  1st International Symposium on Clinical and Experimental Metallodrugs in Medicine: Cancer Chemotherapy
- Place of Presentation
  米国ハワイ州
- Year and Date
  2015-12-13
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015
- Author(s)
  Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
- Organizer
  第25回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  長崎市
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K07905

1. Komeda Seiji (60425056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. HIRAMOTO Keiichi (90251793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HARUSAWA Shinya (90167601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. YOSHIKAWA Yuko (80291871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. 植村雅子 (70511997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 吉川研一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YONEYAMA Hiroki 米山 弘樹

Research Projects

Research Products

Co-Researchers

Drug discovery research based on dinuclear platinum complexes with markedly high antitumor activity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer Tetrazolato-Bridged Dinuclear Platinum(II) Complexes: Middle-Length Alkyl Substituents Exhibit Minimum Effect2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 顕著な抗腫瘍効果を有する白金(II)二核錯体のユニークな作用機構2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 長短鎖アルキル基を導入した制がんテトラゾラト架橋白金(II)二核錯体の細胞 内取込およびDNA凝縮能2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Biological efficiency of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with different length of alkyl substituent in relation to the structural effect of DNA2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Action of novel anticancer-active, dinuclear platinum complexes with ester group on the higher order structure and genomic activity of DNA2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

YONEYAMA Hiroki 米山弘樹

[Presentation] 長短鎖アルキル基を導入した制がんテトラゾラト架橋白金(II)二核錯体の細胞内取込およびDNA凝縮能2016