WATANABE KENJI 渡邊賢司

… Alternative Names

Watanabe Kenji 渡邊賢司

渡辺賢司ワタナベケンジ

WATANABE Kenji 渡辺賢司

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Researcher Number	90631937
Other IDs	https://orcid.org/0000-0001-6249-8666
Affiliation (Current)	2024: 同志社女子大学, 薬学部, 特任助教
Affiliation (based on the past Project Information) *help	2018 – 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 2016 – 2017: 九州大学, 薬学研究院, 特任助教 2013 – 2014: 九州大学, 薬学研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 37010:Bio-related chemistry / Synthetic chemistry / Bio-related chemistry
Keywords	Principal Investigator インドリジン / アミン / カルボン酸 / 光反応 / 生体共役反応 / タンパク質 / 水中反応 / 生体分子修飾 / 複素環化合物 / 共有結合形成反応 … More / アルコール / 中分子化合物 / 環境調和型反応 / 有機合成化学 / ベンジルアルコール / 水酸基活性化 / ベンジリック位水酸基 / インドール / ペプチド / チオール / 包接錯体 / 鉄ポルフィリン / シアン化物イオン / 硫化水素 / シアン化水素 / シクロデキストリン / ポルフィリン Less

Photoinduced bond cleavage and formation of indolizine derivatives and its application to life science researchPrincipal Investigator
- Principal Investigator
  
  渡邊賢司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Institute of Physical and Chemical Research
Development of on-demand bioconjugation/deconjugation methodsPrincipal Investigator
- Principal Investigator
  
  Watanabe Kenji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Institute of Physical and Chemical Research
Development of chemical reactions for realizing precise synthesis of low to high molecular weight bioactive compounds in aqueous solutionsPrincipal Investigator
- Principal Investigator
  
  Watanabe Kenji
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Institute of Physical and Chemical Research
  Kyushu University
Development of Hydrogen Cyanide and Hydrogen Sulfide ReceptorsPrincipal Investigator
- Principal Investigator
  
  WATANABE Kenji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Kyushu University

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013

All Journal Article Presentation Patent

[Journal Article] Red light-induced conjugation of amines through amide bond formation triggered via photooxidation of 3-acylindolizines2022
- Author(s)
  Kenji Watanabe, Asuka Kuratsu, Daisuke Hashizume, Takashi Niwa, Takamitsu Hosoya
- Journal Title
  
  Communications Chemistry
  
  Volume: 5 Issue: 1 Pages: 91-91
- DOI
  10.1038/s42004-022-00712-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05325, KAKENHI-PROJECT-19K05707
[Journal Article] Direct 3-acylation of indolizines by carboxylic acids for the practical synthesis of reed light-releasable caged carboxylic acids2021
- Author(s)
  Kenji Watanabe, Nodoka Terao, Takashi Niwa, Takamitsu Hosoya
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 17 Pages: 11822-11834
- DOI
  10.1021/acs.joc.1c01244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05707
[Journal Article] Indolizines enabling rapid uncaging of alcohols and carboxylic acids by red light-induced photooxidation2020
- Author(s)
  Kenji Watanabe, Nodoka Terao, Isao Kii, Reiko Nakagawa, Takashi Niwa, Takamitsu Hosoya
- Journal Title
  
  Organic Letters
  
  Volume: 22 Issue: 14 Pages: 5434-5438
- DOI
  10.1021/acs.orglett.0c01799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05707, KAKENHI-PROJECT-19H02856
[Journal Article] Covalent Bond Formation between Aromatic Nitro Compounds and Biomolecules2019
- Author(s)
  渡辺賢司
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 77 Issue: 8 Pages: 841-842
- DOI
  10.5059/yukigoseikyokaishi.77.841
- NAID
  130007689047
- ISSN
  0037-9980, 1883-6526
- Year and Date
  2019-08-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05707, KAKENHI-PROJECT-16K17902
[Journal Article] Bioconjugation with Thiols by Benzylic Substitution2018
- Author(s)
  Kenji Watanabe and Takashi Oshima
- Journal Title
  
  Chemistry―A European Journal
  
  Volume: 24 Issue: 16 Pages: 3959-3964
- DOI
  10.1002/chem.201706149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K17902, KAKENHI-PLANNED-15H05846, KAKENHI-PROJECT-17H03972
[Journal Article] Boronic Acid Accelerated Three-Component Reaction for the Synthesis of α-Sulfanyl-Substituted Indole-3-acetic Acids2017
- Author(s)
  Amrita Das, Kenji Watanabe, Hiroyuki Morimoto and Takashi Ohshima
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 21 Pages: 5794-5797
- DOI
  10.1021/acs.orglett.7b02727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K17902, KAKENHI-PLANNED-15H05846, KAKENHI-PROJECT-17H03972, KAKENHI-PROJECT-15K07860
[Journal Article] Reaction between a haemoglobin model compound and hydrosulphide in aqueous solution2015
- Author(s)
  Kenji Watanabe, Toshikane Suzuki, Hiroaki Kitagishi, Koji Kano
- Journal Title
  
  Chemical Communications
  
  Volume: 51 Issue: 19 Pages: 4059-4061
- DOI
  10.1039/c5cc00057b
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25810106
[Journal Article] Supramolecular ferric porphyrins and a cyclodextrin dimer as an antidote for cyanide poisoning2013
- Author(s)
  Yamagiwa T, Kawaguchi AT, Saito T, INoue S, Morita S, Watanabe K, Kitagishi H, Koji K, Inokuchi S.
- Journal Title
  
  Human and experimental toxicology
  
  Volume: Aug5 Issue: 4 Pages: 1-9
- DOI
  10.1177/0960327113499041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249086, KAKENHI-PROJECT-25810106
[Journal Article] Supramolecular iron porphyrin/Cyclodextrin dimer complex that mimics the functions of hemoglobin and methhemoglobin2013
- Author(s)
  Watanabe K, Kitagishi K, Kano K
- Journal Title
  
  Angew Chem Int Ed
  
  Volume: 52 Issue: 27 Pages: 6894-6897
- DOI
  10.1002/anie.201302470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249086, KAKENHI-PROJECT-24750165, KAKENHI-PROJECT-25810106
[Patent] 化合物を放出する方法2021
- Inventor(s)
  渡邊賢司、丹羽節、細谷孝充
- Industrial Property Rights Holder
  理化学研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K05707
[Patent] 化合物を放出する方法2021
- Inventor(s)
  渡邊賢司、丹羽節、細谷孝充
- Industrial Property Rights Holder
  理化学研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K05707
[Patent] 化合物を放出する方法2020
- Inventor(s)
  渡辺賢司、丹羽節、細谷孝充
- Industrial Property Rights Holder
  渡辺賢司、丹羽節、細谷孝充
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-037259
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Photoreactions of indolizines for cleavage and formation of covalent bonds: Toward application for life science research2023
- Author(s)
  Kenji Watanabe, Takashi Niwa, Takamitsu Hosoya
- Organizer
  BDR Retreat 2022
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Photoreactions of indolizines for cleavage and formation of covalent bonds: Toward application for life science research2023
- Author(s)
  Kenji Watanabe, Takashi Niwa, Takamitsu Hosoya
- Organizer
  BDR Retreat 2022
- Data Source
  KAKENHI-PROJECT-22K05325
[Presentation] Development of photo- and radio-caged compounds and demonstration of compound release in vivo using animal models2023
- Author(s)
  Yousuke Kanayama, Kenji Watanabe, Yuka Nakatani, Takashi Niwa, Yasuyoshi Watanabe, Takamitsu Hosoya
- Organizer
  第26回異分野交流の夕べ
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Development of photo- and radio-caged compounds and demonstration of compound release in vivo using animal models2023
- Author(s)
  Yousuke Kanayama, Kenji Watanabe, Yuka Nakatani, Takashi Niwa, Yasuyoshi Watanabe, Takamitsu Hosoya
- Organizer
  第26回異分野交流の夕べ
- Data Source
  KAKENHI-PROJECT-22K05325
[Presentation] Photouncaging-induced amide formation by red light irradiation to indolizines2022
- Author(s)
  Kenji Watanabe, Nodoka Terao, Takashi Niwa, Takamitsu Hosoya
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] インドリジンへの赤色光照射を用いた化合物放出と連結2022
- Author(s)
  渡邊賢司
- Organizer
  第18回六甲有機合成化学勉強会
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Rapid uncaging of alcohols and carboxylic acids by red light-induced photooxidation of indolizines2021
- Author(s)
  Kenji Watanbe, Nodoka Terao, Takashi Niwa, Isao Kii, Reiko Nakagawa, Yousuke Kanayama, Riyo Zouchi, Yuka Nakatani, Yasuyoshi Watanabe, Takamitsu Hosoya
- Organizer
  The 2020 International Chemical Congress of Pacific Basin Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Indolizines enabling rapid uncaging of alcohols and carboxylic acids by red light-induced photooxidation2021
- Author(s)
  Kenji Watanabe, Nodoka Terao, Isao Kii, Reiko Nakagawa, Takashi Niwa, Takamitsu Hosoya
- Organizer
  ACS Spring 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] 生物活性カルボン酸の赤色光誘導放出のための水溶性3-アシル-2-アルコキシインドリジンの合成2021
- Author(s)
  渡邊賢司、寺尾和花、丹羽節、細谷孝充
- Organizer
  日本化学会第101春季年会(2021)
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Rapid photouncaging-induced amide formation by red light irradiation to indolizines2021
- Author(s)
  Kenji Watanabe, Asuka Kuratsu, Takashi Niwa, Takamitsu Hosoya
- Organizer
  International Medicinal Chemistry Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Development of covalent bond formation/cleavage reactions for functionalization of biomolecules2021
- Author(s)
  Kenji Watanabe
- Organizer
  広島大学研究拠点・光ドラッグデリバリー講演会
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] インドリジンへの赤色光照射によるアミンとの共有結合形成反応の開発2021
- Author(s)
  渡邊賢司、倉津飛鳥、丹羽節、細谷孝充
- Organizer
  第54回酸化反応討論会
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] 赤色光を用いたインドリジンの光酸化反応によるアルコールおよびカルボン酸の高速放出2020
- Author(s)
  渡邊賢司、寺尾和花、喜井勲、中川れい子、丹羽節、細谷孝充
- Organizer
  第53回酸化反応討論会
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] 赤色光を用いたインドリジンの光酸化反応によるアルコールおよびカルボン酸の高速放出2020
- Author(s)
  渡邊賢司、寺尾和花、喜井勲、中川れい子、丹羽節、細谷孝充
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Designer indolizines enabling rapid uncaging of alcohols and carboxylic acids by red light-induced photooxidation2020
- Author(s)
  Kenji Watanabe, Nodoka Terao, Isao Kii, Reiko Nakagawa, Takashi Niwa, Takamitsu Hosoya
- Organizer
  第18回次世代を担う有機化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] インドリジンを主骨格とする光ケージド化合物の開発2020
- Author(s)
  渡辺賢司、寺尾和花、丹羽節、細谷孝充
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] 赤色光によるアンケージングが可能な3-アシルインドリジンの簡便合成2020
- Author(s)
  渡邊賢司、寺尾和花、喜井勲、中川れい子、丹羽節、細谷孝充
- Organizer
  反応と合成の進歩2020特別企画シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] 3-アシル-2-アルコキシインドリジンの合成および光反応2020
- Author(s)
  渡邊賢司、寺尾和花、喜井勲、中川れい子、丹羽節、細谷孝充
- Organizer
  Pioneering Project: Chemical Probe（生命現象探索分子）第三回合同セミナー
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] Development of On-Demand Bioconjugation/Deconjugation Platforms2019
- Author(s)
  Kenji Watanabe, Takashi Niwa, Takamitsu Hosoya
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K17902
[Presentation] Development of On-Demand Bioconjugation/Deconjugation Platforms2019
- Author(s)
  Kenji Watanabe, Takashi Niwa, Takamitsu Hosoya
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05707
[Presentation] ベンジリック位チオ化による生体共役反応の開発2018
- Author(s)
  渡辺賢司
- Organizer
  第13回六甲有機合成研究会
- Data Source
  KAKENHI-PROJECT-16K17902
[Presentation] ベンジル位チオール化反応を用いたpH応答性生体共役反応2017
- Author(s)
  渡辺賢司、大嶋孝志
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-16K17902
[Presentation] ベンジル位チオール化反応を用いたpH応答性生体共役反応2017
- Author(s)
  渡辺賢司、大嶋孝志
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K17902
[Presentation] 水溶性鉄ポルフィリン超分子によるシアン化物イオンの捕捉2014
- Author(s)
  渡辺賢司、北岸宏亮、大嶋孝志、加納航治
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25810106
[Presentation] Binding of Inorganic Anions to Supramolecular Complexes of an Anionic Porphyrin and Per-O-Methylated b-Cyclodextrins2013
- Author(s)
  Kano, K.; Kitagishi, H.; Watanabe, K.
- Organizer
  The 7th Asian Cyclodextrin Conference
- Place of Presentation
  Bangkok, Thailand
- Invited
- Data Source
  KAKENHI-PROJECT-25810106

1. 奥直人

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2. 猪口貞樹

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# of Collaborated Products: 1 results
3. 川口章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 加納航治

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WATANABE KENJI 渡邊 賢司

Watanabe Kenji 渡邊 賢司

渡辺 賢司 ワタナベ ケンジ

WATANABE Kenji 渡辺 賢司

Research Projects

Research Products

Co-Researchers

Photoinduced bond cleavage and formation of indolizine derivatives and its application to life science researchPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of on-demand bioconjugation/deconjugation methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of chemical reactions for realizing precise synthesis of low to high molecular weight bioactive compounds in aqueous solutionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Hydrogen Cyanide and Hydrogen Sulfide ReceptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Red light-induced conjugation of amines through amide bond formation triggered via photooxidation of 3-acylindolizines2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct 3-acylation of indolizines by carboxylic acids for the practical synthesis of reed light-releasable caged carboxylic acids2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Indolizines enabling rapid uncaging of alcohols and carboxylic acids by red light-induced photooxidation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Covalent Bond Formation between Aromatic Nitro Compounds and Biomolecules2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Bioconjugation with Thiols by Benzylic Substitution2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Boronic Acid Accelerated Three-Component Reaction for the Synthesis of α-Sulfanyl-Substituted Indole-3-acetic Acids2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reaction between a haemoglobin model compound and hydrosulphide in aqueous solution2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Supramolecular ferric porphyrins and a cyclodextrin dimer as an antidote for cyanide poisoning2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Supramolecular iron porphyrin/Cyclodextrin dimer complex that mimics the functions of hemoglobin and methhemoglobin2013

Author(s)

Journal Title

DOI

Data Source

WATANABE KENJI 渡邊賢司

Watanabe Kenji 渡邊賢司

渡辺賢司ワタナベケンジ

WATANABE Kenji 渡辺賢司