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Ishii Hiroshi  石井 宏史

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HIROSHI ISHII  石井 宏史

ISHII Hiroshi  石井 宏史

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Researcher Number 90634171
Other IDs
Affiliation (Current) 2025: 金沢大学, 医学系, 助教
Affiliation (based on the past Project Information) *help 2022 – 2023: 金沢大学, 医学系, 助教
2017 – 2020: 金沢大学, 医学系, 助教
2013: 大阪大学, 医学系研究科, 助教
2013: 大阪大学, 大学院・医学系研究科, 助教
2012: 大阪大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related / Neurosurgery / Cerebral neurosurgery
Except Principal Investigator
Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords
Principal Investigator
好中球 / 脳血管攣縮 / くも膜下出血 / RAGE / 交感神経 / 早期脳損傷 / 炎症 / 損傷関連分子 / 早期脳障害 / 免疫細胞 … More / M2マクロファージ / M2ミクログリア / インターロイキン10 / インターフェロンγ / Tリンパ球 / RGMa / サイトカイン / リンパ球 / 脊髄損傷 / マクロファージ / ミクログリア / Th1細胞 / 獲得免疫系 / 中枢神経損傷 … More
Except Principal Investigator
炎症 / RAGEシグナル / RAGE / 脳血管障害 Less
  • Research Projects

    (6 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (6 People)
  •  Involvement of sympathetic nervous hyperactivity on early brain injury after subarachnoid hemorrhagePrincipal Investigator

    • Principal Investigator
      石井 宏史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Kanazawa University
  •  Neutrophils induce cerebral vasospasm after subarachnoid hemorrhage through receptor for advanced glycation endproductsPrincipal Investigator

    • Principal Investigator
      Ishii Hiroshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Kanazawa University
  •  Development of RAGE-targeted novel therapy for subarachnoid hemorrhagePrincipal Investigator

    • Principal Investigator
      石井 宏史
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
    • Research Field
      Neurosurgery
    • Research Institution
      Kanazawa University
  •  Joint international research for developing new drugs in the cerebral vascular diseases by targeting RAGE signaling

    • Principal Investigator
      Hori Osamu
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Kanazawa University
  •  Novel molecular immune mechanism underlying cerebral vasospasm after subarachnoid hemorrhage.Principal Investigator

    • Principal Investigator
      HIROSHI ISHII
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Kanazawa University
  •  Functions of adoptive immune system after injury of the central nervous system and immunomodulatory treatmentPrincipal Investigator

    • Principal Investigator
      ISHII Hiroshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Osaka University

All 2019 2018 2017 2013 2012

All Journal Article Presentation

  • [Journal Article] Soluble receptor for advanced glycation end products as a biomarker of symptomatic vasospasm in subarachnoid hemorrhage.2019

    • Author(s)
      Aida Y, Kamide T, Ishii H, Kitao Y, Uchiyama N, Nakada M, Hori O.
    • Journal Title

      J Neurosurg.

      Volume: Nov 1 Issue: 1 Pages: 1-9

    • DOI

      10.3171/2019.8.jns191269

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06500, KAKENHI-PROJECT-18KK0255
  • [Journal Article] Neuroprotective Effects of Endogenous Secretory Receptor for Advanced Glycation End-products in Brain Ischemia2019

    • Author(s)
      Yu Shimizu, Ai Harashima, Seiichi Munesue, Masahiro Oishi, Tsuyoshi Hattori, Osamu Hori, Yasuko Kitao, Hiroshi Yamamoto, Nontaphat Leerach, Mitsutoshi Nakada, Yasuhiko Yamamoto, Yasuhiko Hayashi
    • Journal Title

      Aging and Disease

      Volume: 印刷中

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0255
  • [Journal Article] Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination2019

    • Author(s)
      Roboon Jureepon、Hattori Tsuyoshi、Ishii Hiroshi、Takarada-Iemata Mika、Le Thuong Manh、Shiraishi Yoshitake、Ozaki Noriyuki、Yamamoto Yasuhiko、Sugawara Akira、Okamoto Hiroshi、Higashida Haruhiro、Kitao Yasuko、Hori Osamu
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 13 Pages: 258-258

    • DOI

      10.3389/fncel.2019.00258

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09031, KAKENHI-PROJECT-18K06463, KAKENHI-PROJECT-18K06500, KAKENHI-PROJECT-18K06501, KAKENHI-PROJECT-18K06889, KAKENHI-PROJECT-18KK0435, KAKENHI-PROJECT-18KK0255
  • [Journal Article] Ndrg2 deficiency ameliorates neurodegeneration in experimental autoimmune encephalomyelitis2018

    • Author(s)
      Le Thuong Manh、Takarada-Iemata Mika、Ta Hieu Minh、Roboon Jureepon、Ishii Hiroshi、Tamatani Takashi、Kitao Yasuko、Hattori Tsuyoshi、Hori Osamu
    • Journal Title

      Journal of neurochemistry

      Volume: 印刷中 Issue: 2 Pages: 139-153

    • DOI

      10.1111/jnc.14294

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06753, KAKENHI-PROJECT-18K06500, KAKENHI-PROJECT-18KK0255
  • [Journal Article] N-myc downstream-regulated gene 2 protects blood-brain barrier integrity following cerebral ischemia2018

    • Author(s)
      Takarada-Iemata Mika、Yoshikawa Akifumi、Ta Hieu Minh、Okitani Nahoko、Nishiuchi Takumi、Aida Yasuhiro、Kamide Tomoya、Hattori Tsuyoshi、Ishii Hiroshi、Tamatani Takashi、Le Thuong Manh、Roboon Jureepon、Kitao Yasuko、Matsuyama Tomohiro、Nakada Mitsutoshi、Hori Osamu
    • Journal Title

      Glia

      Volume: 印刷中 Issue: 7 Pages: 1432-1446

    • DOI

      10.1002/glia.23315

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06753, KAKENHI-PROJECT-18K06500, KAKENHI-PROJECT-18KK0255
  • [Journal Article] Interferon-gamma-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury2013

    • Author(s)
      Ishii H, Tanabe S, Ueno M, Kubo T, Kayama H,Serada S, Fujimoto M, Takeda K, Naka T, and Yamashita T
    • Journal Title

      Cell Death and Disease Nature Publishing Group

      Volume: 4

    • Data Source
      KAKENHI-PROJECT-24890113
  • [Journal Article] Interferon-gamma-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury.2013

    • Author(s)
      Ishii H
    • Journal Title

      Cell Death and Disease

      Volume: 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890113
  • [Journal Article] Adoptive transfer of Th1-conditioned lymphocytes promotes axonal remodeling and functional recovery after spinal cord lnJury2012

    • Author(s)
      Ishii H, Jin X, Ueno M, Tanabe S, Kubo, Serada S, Naka T. Yamashita T
    • Journal Title

      Cell Death Dis

      Volume: 3 Issue: 8 Pages: e363-e363

    • DOI

      10.1038/cddis.2012.106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591101, KAKENHI-PROJECT-24890113
  • [Journal Article] Adoptive transfer of Th1-conditioned lymphocytes promotes axonal remodeling and functional recovery after spinal cord irljury2012

    • Author(s)
      Ishii H, Jin X, Ueno M, Tanabe S, Kubo T, Serada S, Naka T, Yamashita T
    • Journal Title

      Cell Death and Disease Nature Publishing Group

      Volume: 3

    • Data Source
      KAKENHI-PROJECT-24890113
  • [Presentation] DAMPs-dependent neutrophil migration is critical pathology in cerebral vasospasm after SAH2019

    • Author(s)
      石井宏史、堀修
    • Organizer
      第62回日本脳循環代謝学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18KK0255
  • [Presentation] Peripheral leukocyte accumulation in the brain is critical pathology of cerebral vasospasm/neuronal dysfunction after subdural arachnoid hemorrhage2018

    • Author(s)
      石井宏史、堀修
    • Organizer
      日本解剖学会 第78回中部支部学術集会
    • Data Source
      KAKENHI-PROJECT-18KK0255
  • [Presentation] くも膜下出血マウスモデルにおける早期脳損傷病態2017

    • Author(s)
      石井 宏史
    • Organizer
      日本解剖学会
    • Data Source
      KAKENHI-PROJECT-17K10821
  • [Presentation] IFN-_Y and IL-10 are required for neuroprotection by Th1 cells after spinal cord inj ury2012

    • Author(s)
      Ishii H, Kubo T, Naka T, Yamashita T
    • Organizer
      Neuroscience 2012, Society for Neuroscience Daily Books Book Six, page43
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2012-10-17
    • Data Source
      KAKENHI-PROJECT-24890113
  • [Presentation] IFN-γ and IL-10 are required for neuroprotection by Th1 cells after spinal cord injury.2012

    • Author(s)
      Hiroshi Ishii
    • Organizer
      Neuroscience 2012, Society for Neuroscience
    • Place of Presentation
      New Orleans, LA, USA
    • Data Source
      KAKENHI-PROJECT-24890113
  • 1.  Hori Osamu (60303947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  宝田 美佳 (40565412)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  出村 宗大 (10881039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  仲 哲治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  服部 剛志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  尾崎 紀之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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