Shimomura Kenju 下村健寿

… Alternative Names

SHIMOMURA Kenju 下村健寿

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Researcher Number	90636226
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 福島県立医科大学, 医学部, 教授 2017: 福島県立医科大学, 医学部・病態制御薬理医学講座, 教授 2014: 福島県立医科大学, 医学部, 特任教授 2014: 福島県立医科大学, 医学部・腫瘍生体エレクトロニクス講座, 特任教授 2012 – 2013: 自治医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator KATPチャネル / インスリン分泌 / 新生児糖尿病 / 認知症 / PIP2 / 電気生理 / 活動電位 / 視床下部ニューロン / 肥満 / 生活習慣病 … More / 加齢 / フレイル / サルコペニア / サルコペニア・フレイル / ＫＡＴＰチャネル / 過食 / 脳室傍核 / オレキシン / オキシトシン / DEND症候群 … More Except Principal Investigator 肥満 / オキシトシン / 摂食 / 腹側被蓋野 / GABA / 報酬系 / 幼若期 / 過食 / 成長 / メタボリックシンドローム / マウス / 食欲 / GLP-1 / 摂食制御 / ネスファチン / 摂食リズム / 視交叉上核 / バソプレッシン / 光 / 室傍核 / 視索上核 Less

脳KATPチャネル活性による認知症病態機序の解明と治療への応用Principal Investigator
- Principal Investigator
  
  下村健寿
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Fukushima Medical University
Regulation of KATP channel and insulin secretion by PIP2 and its application to diabetes treatmentPrincipal Investigator
- Principal Investigator
  
  Shimomura Kenju
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Fukushima Medical University
The study of anti-obesity effect by recovery of endogenous oxytocin secretion and its clinical implication
- Principal Investigator
  
  Maejima Yuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Fukushima Medical University
Involvement of brain KATP channel with pathology of sarcopenia and frailityPrincipal Investigator
- Principal Investigator
  
  Shimomura Kenj
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Fukushima Medical University
The study of development of oxytocinergic neutral circuit responding to energy status in childhood
- Principal Investigator
  
  Maejima Yuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Fukushima Medical University
Contribution of KATP channel in PVN oxytocin neurons for food intake regulation.Principal Investigator
- Principal Investigator
  
  Shimomura Kenju
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Fukushima Medical University
Nesfatin-1
- Principal Investigator
  
  MAEJIMA Yuko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Fukushima Medical University
  Jichi Medical University
Neuronal feature of neonatal diabetes and investigation of neuronal feature of KATP channel in brainPrincipal Investigator
- Principal Investigator
  
  SHIMOMURA Kenju
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical University

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All Journal Article Presentation Book

[Book] 最強の医師団が教える長生きできる方法2020
- Author(s)
  坂本昌也、頴川晋、北原雅樹、齋田良知、繁田雅弘、下村健寿、炭山和毅、鳥海弥寿雄、前島裕子、三澤健之
- Total Pages
  216
- Publisher
  アスコム
- ISBN
  9784776211006
- Data Source
  KAKENHI-PROJECT-18K08483
[Book] 神経内科　漢方薬からみた視床下部オキシトシンニューロンに対する作用2018
- Author(s)
  前島裕子　下村健寿
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-15K09395
[Journal Article] Systemic co-administration of low dose oxytocin and glucagon like peptide-1 additively decreases food intake and body weight2024
- Author(s)
  Maejima Yuko、Yokota Shoko、Hidema Shizu、Nishimori Katsuhiko、de Wet Heidi、Shimomura Kenju
- Journal Title
  
  Neuroendocrinology
  
  Volume: ahead Issue: 7 Pages: 547-547
- DOI
  10.1159/000538792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08012
[Journal Article] Dose Dependent Effect of Sulfamethoxazole on Inhibiting K<sub>ATP</sub> Channel of Mouse Pancreatic β Cell2023
- Author(s)
  Ogata Hiroshi、Kitamura Shigeki、Fujiwara Makoto、Shimizu Masaru、Tan Chengbo、Zhao Songji、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  Dose-Response
  
  Volume: 21 Issue: 3 Pages: 155-155
- DOI
  10.1177/15593258231203611
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08012
[Journal Article] Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion2023
- Author(s)
  Kitamura Shigeki、Murao Naoya、Yokota Shoko、Shimizu Masaru、Ono Tomoyuki、Seino Yusuke、Suzuki Atsushi、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  BMC Research Notes
  
  Volume: 16 Issue: 1 Pages: 202-202
- DOI
  10.1186/s13104-023-06489-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08012, KAKENHI-PROJECT-21K11608
[Journal Article] Oxytocin Receptor-Expressing Neurons in the Medial Preoptic Area Are Essential for Lactation, whereas Those in the Lateral Septum Are Not Critical for Maternal Behavior2023
- Author(s)
  Hidema Shizu、Sato Keisuke、Mizukami Hiroaki、Takahashi Yumi、Maejima Yuko、Shimomura Kenju、Nishimori Katsuhiko
- Journal Title
  
  Neuroendocrinology
  
  Volume: ahead Issue: 6 Pages: 517-537
- DOI
  10.1159/000535362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08012, KAKENHI-PROJECT-23K08020, KAKENHI-PROJECT-21K11726
[Journal Article] Successful treatment of nivolumab and ipilimumab triggered type 1 diabetes by using sodium-glucose transporter 2 inhibitor: a case report and systematic review2023
- Author(s)
  Fujiwara Makoto、Shimizu Masaru、Okano Tatsuya、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  Frontiers in Public Health
  
  Volume: 11 Pages: 1264056-1264056
- DOI
  10.3389/fpubh.2023.1264056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08012
[Journal Article] Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia2022
- Author(s)
  Maejima Yuko、Horita Shoichiro、Yokota Shoko、Yamachi Megumi、Shimizu Masaru、Ono Tomoyuki、Yu Zhiquian、Tomita Hiroaki、Shimomura Kenju
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 120 Pages: 103734-103734
- DOI
  10.1016/j.mcn.2022.103734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07962, KAKENHI-PROJECT-20K08865
[Journal Article] Identification of oxytocin expression in human and murine microglia2022
- Author(s)
  Maejima Yuko、Yokota Shoko、Ono Tomoyuki、Yu Zhiqian、Yamachi Megumi、Hidema Shizu、Nollet Kenneth E.、Nishimori Katsuhiko、Tomita Hiroaki、Yaginuma Hiroyuki、Shimomura Kenju
- Journal Title
  
  Progress in Neuro-Psychopharmacology and Biological Psychiatry
  
  Volume: 119 Pages: 110600-110600
- DOI
  10.1016/j.pnpbp.2022.110600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07962, KAKENHI-PROJECT-20K08865
[Journal Article] Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia2022
- Author(s)
  Yuko Maejima, Shoichiro Horita, Shoko Yokota, Megumi Yamachi, Masaru Shimizu, Tomoyuki Ono, Zhiquian Yu, Hiroaki Tomita, Kenju Shimomura
- Journal Title
  
  Molecular Cell Neuroscence
  
  Volume: 120 Pages: 103734-103734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08865
[Journal Article] Efficacy of SGLT2 inhibitors as additional treatment in Japanese type 2 diabetic patients: second or third choice?2022
- Author(s)
  Fujiwara Makoto、Shimizu Masaru、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  BMC Research Notes
  
  Volume: 15 Issue: 1 Pages: 120-120
- DOI
  10.1186/s13104-022-06010-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08865
[Journal Article] Optimization of the use of Py?Tag for next generation derivatization reagents in imaging mass spectrometry2022
- Author(s)
  Shikano Hitomi、Ikeda Akari、Maejima Yuko、Kobayashi Shoko、Terauchi Tsutomu、Yokoyama Jun、Shimomura Kenju、Taira Shu
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 134 Issue: 3 Pages: 264-268
- DOI
  10.1016/j.jbiosc.2022.06.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-23K21178
[Journal Article] The effects of ninjin’yoeito on the electrophysiological properties of dopamine neurons in the ventral tegmental area/substantia nigra pars compacta and medium spiny neurons in the nucleus accumbens2022
- Author(s)
  Imai Ryota、Mizuno Keita、Omiya Yuji、Mizoguchi Kazushige、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  Aging
  
  Volume: 14 Issue: 11 Pages: 4634-4652
- DOI
  10.18632/aging.204109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08865
[Journal Article] C188-9, a specific inhibitor of STAT3 signaling, prevents thermal burn-induced skeletal muscle wasting in mice2022
- Author(s)
  Ono Yuko、Saito Masafumi、Sakamoto Kazuho、Maejima Yuko、Misaka Shingen、Shimomura Kenju、Nakanishi Nobuto、Inoue Shigeaki、Kotani Joji
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 1031906-1031906
- DOI
  10.3389/fphar.2022.1031906
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09181, KAKENHI-PROJECT-20K08865
[Journal Article] Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers2022
- Author(s)
  Misaka Shingen、Ono Yuko、Taudte R. Verena、Hoier Eva、Ogata Hiroshi、Ono Tomoyuki、Konig Jorg、Watanabe Hiroshi、Fromm Martin F.、Shimomura Kenju
- Journal Title
  
  Clinical Pharmacology & Therapeutics
  
  Volume: 112 Issue: 3 Pages: 627-634
- DOI
  10.1002/cpt.2682
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09181, KAKENHI-PROJECT-20K08865
[Journal Article] Evaluation of organ glucose metabolism by 18F-FDG accumulation with insulin loading in aged mice compared with young normal mice2021
- Author(s)
  Zhao Jingmin、Tan Chengbo、Imai Ryota、Ukon Naoyuki、Shimoyama Saki、Maejima Yuko、Omiya Yuji、Takahashi Kazuhiro、Ito Hiroshi、Nan Guangxian、Zhao Songji、Shimomura Kenju
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 7421-7421
- DOI
  10.1038/s41598-021-86825-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08031, KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-21K15831, KAKENHI-PROJECT-18K08483
[Journal Article] Urinary Excretion of Nadolol as a Possible In Vivo Probe for Drug Interactions Involving P‐Glycoprotein2021
- Author(s)
  Shimazaki Sho、Kuroda Junko、Shimomura Kenju、Misaka Shingen
- Journal Title
  
  The Journal of Clinical Pharmacology
  
  Volume: 61 Issue: 6 Pages: 799-805
- DOI
  10.1002/jcph.1812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-17K17983
[Journal Article] The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity2021
- Author(s)
  Maejima Yuko、Yokota Shoko、Shimizu Masaru、Horita Shoichiro、Kobayashi Daisuke、Hazama Akihiro、Shimomura Kenju
- Journal Title
  
  Nutrition & Metabolism
  
  Volume: 18 Issue: 1 Pages: 58-58
- DOI
  10.1186/s12986-021-00582-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08865
[Journal Article] Structure based analysis of KATP channel with a DEND syndrome mutation in murine skeletal muscle2021
- Author(s)
  Horita Shoichiro、Ono Tomoyuki、Gonzalez-Resines Saul、Ono Yuko、Yamachi Megumi、Zhao Songji、Domene Carmen、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 6668-6668
- DOI
  10.1038/s41598-021-86121-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-18K08483
[Journal Article] Detection of NUCB2/nesfatin-1 in cerebrospinal fluid of multiple sclerosis patients2020
- Author(s)
  Shimizu Masaru、Manome Taizo、Kumami Masumi、Matsumura Kouzou、Kanai Kazuaki、Shimomura Kenju、Maejima Yuko
- Journal Title
  
  Aging
  
  Volume: 12 Issue: 23 Pages: 24134-24140
- DOI
  10.18632/aging.202287
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-18K08483
[Journal Article] Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers2020
- Author(s)
  Misaka Shingen、Ono Yuko、Uchida Atsushi、Ono Tomoyuki、Abe Osamu、Ogata Hiroshi、Sato Hideyuki、Suzuki Masahiko、Onoue Satomi、Shikama Yayoi、Shimomura Kenju
- Journal Title
  
  Clinical and Translational Science
  
  Volume: 14 Issue: 2 Pages: 476-480
- DOI
  10.1111/cts.12905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-17K17983, KAKENHI-PROJECT-18K16544
[Journal Article] Oral oxytocin delivery with proton pump inhibitor pretreatment decreases food intake2020
- Author(s)
  Maejima Yuko、Horita Shoichiro、Otsuka Ayano、Hidema Shizu、Nishimori Katsuhiko、Shimomura Kenju
- Journal Title
  
  Peptides
  
  Volume: 128 Pages: 170312-170312
- DOI
  10.1016/j.peptides.2020.170312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07745, KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-18K08483
[Journal Article] TAK-242, a Specific Inhibitor of Toll-like Receptor 4 Signalling, Prevents Endotoxemia-Induced Skeletal Muscle Wasting in Mice.2020
- Author(s)
  Yuko Ono, Yuko Maejima, Masafumi Saito, Kazuho Sakamoto, Shoichiro Horita, Kenju Shimomura, Shigeaki Inoue, Joji Kotani
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 694-694
- DOI
  10.1038/s41598-020-57714-3
- NAID
  120006796507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06897, KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-17K09840
[Journal Article] Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway2020
- Author(s)
  Iseki Yuzo、Ono Yuko、Hibi Chihiro、Tanaka Shoko、Takeshita Shunya、Maejima Yuko、Kurokawa Junko、Murakawa Masahiro、Shimomura Kenju、Sakamoto Kazuho
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 376 Issue: 3 Pages: 454-462
- DOI
  10.1124/jpet.120.000290
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-18K06897, KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-19H03380
[Journal Article] Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models2020
- Author(s)
  Horiai Machi、Otsuka Ayano、Hidema Shizu、Hiraoka Yuichi、Hayashi Ryotaro、Miyazaki Shinji、Furuse Tamio、Mizukami Hiroaki、Teruyama Ryoichi、Tamura Masaru、Bito Haruhiko、Maejima Yuko、Shimomura Kenju、Nishimori Katsuhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 22173-22173
- DOI
  10.1038/s41598-020-79109-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-19H03457, KAKENHI-PROJECT-18K08483
[Journal Article] Early life high-fat diet exposure evokes normal weight obesity2020
- Author(s)
  Maejima Yuko、Yokota Shoko、Horita Shoichiro、Shimomura Kenju
- Journal Title
  
  Nutrition & Metabolism
  
  Volume: 17 Issue: 1 Pages: 2020-2020
- DOI
  10.1186/s12986-020-00464-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-18K08483
[Journal Article] Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes2020
- Author(s)
  Oduori Okechi S.、Murao Naoya、Shimomura Kenju、Takahashi Harumi、Zhang Quan、Dou Haiqiang、Sakai Shihomi、Minami Kohtaro、Chanclon Belen、Guida Claudia、Kothegala Lakshmi、Tol? Johan、Maejima Yuko、Yokoi Norihide、Minami Yasuhiro、Miki Takashi、Rorsman Patrik、Seino Susumu
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 130 Issue: 12 Pages: 6639-6655
- DOI
  10.1172/jci140046
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07281, KAKENHI-PROJECT-19K07400, KAKENHI-PROJECT-19K09026, KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-18H02364, KAKENHI-PROJECT-18K08483
[Journal Article] Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells2020
- Author(s)
  Imai Ryota、Horita Shoichiro、Ono Yuko、Hagihara Keisuke、Shimizu Masaru、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  BioResearch Open Access
  
  Volume: 9 Issue: 1 Pages: 116-120
- DOI
  10.1089/biores.2019.0034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-19K07937, KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-18K08483
[Journal Article] Effects of single green tea ingestion on pharmacokinetics of nadolol in healthy volunteers2020
- Author(s)
  Misaka Shingen、Abe Osamu、Ono Tomoyuki、Ono Yuko、Ogata Hiroshi、Miura Itaru、Shikama Yayoi、Fromm Martin F.、Yabe Hirooki、Shimomura Kenju
- Journal Title
  
  British Journal of Clinical Pharmacology
  
  Volume: - Issue: 11 Pages: 2314-2318
- DOI
  10.1111/bcp.14315
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-20K08865, KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-17K17983
[Journal Article] Atorvastatin?Green Tea Interaction: Possible Mechanisms are Complicated, But Clinical Relevance is Not?2020
- Author(s)
  Misaka Shingen、Shimomura Kenju
- Journal Title
  
  European Journal of Drug Metabolism and Pharmacokinetics
  
  Volume: 45 Issue: 3 Pages: 423-425
- DOI
  10.1007/s13318-020-00620-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-17K17983
[Journal Article] Single administration of resveratrol improves social behavior in adult mouse models of autism spectrum disorder2020
- Author(s)
  Hidema Shizu、Kikuchi Shohei、Takata Ryoji、Yanai Takaaki、Shimomura Kenju、Horie Kengo、Nishimori Katsuhiko
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 84 Issue: 11 Pages: 2207-2214
- DOI
  10.1080/09168451.2020.1794783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08865
[Journal Article] LGR4 is essential for R-spondin1-mediated suppression of food intake via pro-opiomelanocortin2019
- Author(s)
  Otsuka Ayano、Jinguji Ayana、Maejima Yuko、Kasahara Yoshiyuki、Shimomura Kenju、Hidema Shizu、Nishimori Katsuhiko
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 83 Issue: 7 Pages: 1336-1342
- DOI
  10.1080/09168451.2019.1591266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] Noninvasive continuous blood pressure monitoring using microelectromechanical system technology2019
- Author(s)
  Satake Shuichi、Shimura Tatsuo、Ono Tetsuya、Shimomura Kenju、Takenoshita Seiichi、Kono Koji
- Journal Title
  
  Blood Pressure Monitoring
  
  Volume: 24 Issue: 3 Pages: 155-159
- DOI
  10.1097/mbp.0000000000000380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] Association between cognitive impairment patient with solid cancer and insulin resistance2019
- Author(s)
  Gonda Kenji、Yaginuma Kenji、Rokkaku Yuichi、Horita Shoichiro、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  BMC Research Notes
  
  Volume: 12 Issue: 1 Pages: 705-705
- DOI
  10.1186/s13104-019-4739-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] The hypothalamus to brainstem circuit suppresses late-onset body weight gain2019
- Author(s)
  Maejima Yuko、Kato Shigeki、Horita Shoichiro、Ueta Yoichi、Takenoshita Seiichi、Kobayashi Kazuto、Shimomura Kenju
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 18360-18360
- DOI
  10.1038/s41598-019-54870-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats2019
- Author(s)
  Maejima Yuko、Yokota Shoko、Horita Shoichiro、Shimomura Kenju
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 11848-11848
- DOI
  10.1038/s41598-019-48336-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids2019
- Author(s)
  Takahashi Nobuhiko、Hoshi Hirotaka、Higa Arisa、Hiyama Gen、Tamura Hirosumi、Ogawa Mayu、Takagi Kosuke、Goda Kazuhito、Okabe Naoyuki、Muto Satoshi、Suzuki Hiroyuki、Shimomura Kenju、Watanabe Shinya、Takagi Motoki
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 5 Pages: 481-481
- DOI
  10.3390/cells8050481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09310, KAKENHI-PROJECT-17K09840
[Journal Article] MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45?years2019
- Author(s)
  Momma Tomoyuki、Gonda Kenji、Akama Yoshinori、Endo Eisei、Ujiie Daisuke、Fujita Shotaro、Maejima Yuko、Horita Shoichiro、Shimomura Kenju、Saji Shigehira、Kono Koji、Yashima Rei、Watanabe Fumiaki、Sugano Kokichi、Nomizu Tadashi
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 20 Issue: 1 Pages: 67-67
- DOI
  10.1186/s12881-019-0792-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08712, KAKENHI-PROJECT-17K09840
[Journal Article] Impact of dapagliflozin, an SGLT2 inhibitor, on serum levels of soluble dipeptidyl peptidase‐4 in patients with type 2 diabetes and non‐alcoholic fatty liver disease2019
- Author(s)
  Aso Yoshimasa、Kato Kanako、Sakurai Shintaro、Kishi Haruka、Shimizu Masanori、Jojima Teruo、Iijima Toshie、Maejima Yuko、Shimomura Kenju、Usui Isao
- Journal Title
  
  International Journal of Clinical Practice
  
  Volume: 73 Issue: 5 Pages: e13335-e13335
- DOI
  10.1111/ijcp.13335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma2019
- Author(s)
  Jojima Teruo、Wakamatsu Sho、Kase Masato、Iijima Toshie、Maejima Yuko、Shimomura Kenju、Kogai Takahiko、Tomaru Takuya、Usui Isao、Aso Yoshimasa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 20 Pages: 5237-5237
- DOI
  10.3390/ijms20205237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report2019
- Author(s)
  Gonda Kenji、Akama Takanori、Nakamura Takayuki、Hashimoto Eiko、Kyoya Naomi、Rokkaku Yuichi、Maejima Yuko、Horita Shoichiro、Tachibana Kazunoshin、Abe Noriko、Ohtake Tohru、Shimomura Kenju、Kono Koji、Saji Shigehira、Takenoshita Seiichi、Higashihara Eiji
- Journal Title
  
  Journal of Medical Case Reports
  
  Volume: 13 Issue: 1 Pages: 381-381
- DOI
  10.1186/s13256-019-2274-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] The effect of avertin anesthesia and a mixture of three types of anesthetic agents on food intakeand body weight in high fat-induced obese maleand female mice2019
- Author(s)
  Maejima Yuko、Yokota Shoko、O’Hashi Rie、Aoyama Masato、Shimomura Kenju
- Journal Title
  
  Exp. Anim.
  
  Volume: 68 Issue: 1 Pages: 57-69
- DOI
  10.1538/expanim.17-0145
- NAID
  130007604478
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] Memantine has no effect on KATP channels in pancreatic β cells2018
- Author(s)
  Imai Ryota、Misaka Shingen、Horita Shoichiro、Yokota Shoko、O’hashi Rie、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  BMC Research Notes
  
  Volume: 11 Issue: 1 Pages: 614-614
- DOI
  10.1186/s13104-018-3715-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-17K17983
[Journal Article] Excitability of oxytocin neurons in paraventricular nucleus is regulated by voltage-gated potassium channels Kv4.2 and Kv4.32018
- Author(s)
  Imai Ryota、Yokota Shoko、Horita Shoichiro、Ueta Yoichi、Maejima Yuko、Shimomura Kenju
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 83 Issue: 2 Pages: 202-211
- DOI
  10.1080/09168451.2018.1537773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] Action Selection and Flexible Switching Controlled by the Intralaminar Thalamic Neurons2018
- Author(s)
  Kato Shigeki、Fukabori Ryoji、Nishizawa Kayo、Okada Kana、Yoshioka Nozomu、Sugawara Masateru、Maejima Yuko、Shimomura Kenju、Okamoto Masahiro、Eifuku Satoshi、Kobayashi Kazuto
- Journal Title
  
  Cell Reports
  
  Volume: 22 Issue: 9 Pages: 2370-2382
- DOI
  10.1016/j.celrep.2018.02.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07155, KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-17K14951, KAKENHI-PROJECT-25702053, KAKENHI-PROJECT-15H05400, KAKENHI-PROJECT-16J40090
[Journal Article] The anorexigenic neural pathways of oxytocin and clinical implication2018
- Author(s)
  Maejima Y, Yokota S, Nishimori K, Shimomura K
- Journal Title
  
  Neuroendocrinology
  
  Volume: 印刷中 Issue: 1 Pages: 91-104
- DOI
  10.1159/000489263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-15K09395, KAKENHI-PUBLICLY-16H01480
[Journal Article] Orexin action on oxytocin neurons in the paraventricular nucleus of the hypothalamus.2017
- Author(s)
  Maejima Y, Takahashi Shinichi, Takasu Katsuya, Takenoshita Seiichi, Ueta Yoichi, Shimomura Kenju.
- Journal Title
  
  Neuro Rreport
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09395
[Journal Article] Non-alcoholic fatty liver disease is a risk factor for type 2 diabetes in middle-aged Japanese men and women2017
- Author(s)
  Tokita Y, Maejima Y, Shimomura K, Takenoshita S, Ishiyama N, Akuzawa M, Shimomura Y, Nakajima K.
- Journal Title
  
  Internal Medicine
  
  Volume: 56 Pages: 763771-763771
- NAID
  130005530252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461366
[Journal Article] Impact of sex, fat distribution and initial body weight on oxytocin's body weight regulation.2017
- Author(s)
  Maejima Y, Aoyama M, Sakamoto K, Jojima T, Aso Y, Takasu K, Takenoshita S, Shimomura K
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 8599-8599
- DOI
  10.1038/s41598-017-09318-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-15K09395
[Journal Article] Orexin action on oxytocin neurons in the paraventricular nucleus of the hypothalamus.2017
- Author(s)
  Maejima Y, Takahashi S, Takasu K, Takenoshita S, Ueta Y, Shimomura K.
- Journal Title
  
  Neuroreport
  
  Volume: 28 Issue: 6 Pages: 360366-360366
- DOI
  10.1097/wnr.0000000000000773
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461366, KAKENHI-PROJECT-15K09395, KAKENHI-PROJECT-15K10500
[Journal Article] K<sub>ATP</sub> Channel Mutations and Neonatal Diabetes2017
- Author(s)
  Shimomura K, Maejima Y
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 18 Pages: 2387-2393
- DOI
  10.2169/internalmedicine.8454-16
- NAID
  130006078621
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840
[Journal Article] Nesfatin-1 inhibits voltage gated K-channels in pancreatic beta cells.2017
- Author(s)
  Maejima Y, Horita S, Kobayashi D, Aoki M, O'hashi R, Imai R, Sakamoto K, Mori M, Takasu K, Ogawa K, Takenoshita S, Zhao S, Hazama A, Shimomura K
- Journal Title
  
  Peptides
  
  Volume: 95 Pages: 1015-1015
- DOI
  10.1016/j.peptides.2017.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09840, KAKENHI-PROJECT-15K09395
[Journal Article] Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women2017
- Author(s)
  Tokita Y, Maejima Y, Shimomura K, Takenoshita S, Ishiyama N, Akuzawa M, Shimomura Y, Nakajima K.
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 7 Pages: 763-771
- DOI
  10.2169/internalmedicine.56.7115
- NAID
  130005530252
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09395
[Journal Article] Islet Insulin Secretion Measurements in the Mouse.2016
- Author(s)
  Hugill A, Shimomura K, Cox RD
- Journal Title
  
  Curr Protoc Mouse Biol.
  
  Volume: 1 Issue: 3 Pages: 256-271
- DOI
  10.1002/cpmo.14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461366
[Journal Article] Impact of visceral fat area measured by dual impedance method on diagnostic components of metabolic diseases in a middle-aged Japanese population2016
- Author(s)
  Sakamaki K, Maejima Y, Tokita Y, Masamura Y, Kumamoto K, Akuzawa M, Nagano N, Nakajima K, Shimomura K, Takenoshita S, Shimomura Y
- Journal Title
  
  Ｉｎｔｅｒｎａｌ　Ｍｅｄｉｃｉｎｅ
  
  Volume: ｉｎ　ｐｒｅｓｓ
- NAID
  130005161034
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09395
[Journal Article] Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells.2016
- Author(s)
  Brereton MF, Rohm M, Shimomura K, Holland C, Tornovsky-Babeay S, Dadon D, Iberl M, Chibalina MV, Lee S, Glaser B, Dor Y, Rorsman P, Clark A, Ashcroft FM.
- Journal Title
  
  Nature Communications
  
  Volume: 24 Issue: 1 Pages: 13496-13496
- DOI
  10.1038/ncomms13496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461366
[Journal Article] Projections from a single NUCB2/nesfatin-1 neuron in the paraventricular nucleus to different brain regions involved in feeding.2016
- Author(s)
  Maejima Y, Kumamoto K, Takenoshita S, Shimomura K.
- Journal Title
  
  Brain Structure & Function
  
  Volume: 221 Pages: 4723-4731
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09395
[Journal Article] Impact of the Visceral Fat Area Measured by Dual Impedance Method on the Diagnostic Components of Metabolic Diseases in a Middle-aged Japanese Population2016
- Author(s)
  Sakamaki K, Maejima Y, Tokita Y, Masamura Y, Kumamoto K, Akuzawa M, Nagano N, Nakajima K, Shimomura K, Takenoshita S, Shimomura Y
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 13 Pages: 1691-1696
- DOI
  10.2169/internalmedicine.55.6088
- NAID
  130005161034
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461366
[Journal Article] Projections from single NUCB2/nesfatin-1 neuron in paraventricular nucleus to different brain regions involved in feeding2016
- Author(s)
  Maejima Y, Kumamoto K, Takenoshita S, Shimomura K
- Journal Title
  
  Ｂｒａｉｎ　Ｓｔｒｕｃｔｕｒｅ　ａｎｄ　Ｆｕｎｃｔｉｏｎ
  
  Volume: ｉｎ　ｐｒｅｓｓ Pages: 123-137
- DOI
  10.1016/j.yjmcc.2016.03.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09395, KAKENHI-PROJECT-15H04817, KAKENHI-PROJECT-26461126, KAKENHI-PROJECT-16K15422, KAKENHI-PROJECT-16K15199, KAKENHI-PROJECT-15H04806
[Journal Article] Central action of ELABELA reduces food intake and activates arginine vasopressin and corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus.2015
- Author(s)
  Santoso P, Maejima Y, Kumamoto K, Takenoshita S, Shimomura K.
- Journal Title
  
  Ｎｅｕｒｏｒｅｐｏｒｔ
  
  Volume: 26 Issue: 14 Pages: 820-826
- DOI
  10.1097/wnr.0000000000000431
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09395, KAKENHI-PROJECT-26461366
[Journal Article] Water intake disorder in a DEND syndrome afflicted patient with R50P mutation2015
- Author(s)
  Maejima Y, Hasegawa S, Horita S, Kumamoto K, Galbanovskis J, Takenoshita S, Shimomura K.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 4 Pages: 387-392
- DOI
  10.1507/endocrj.EJ14-0392
- NAID
  130005066941
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659619, KAKENHI-PROJECT-26461366, KAKENHI-PROJECT-15K09395
[Journal Article] Projection from a single NUCB2/nesfatin-1 neuron in the paraventricular nucleus to different brain regions involved in feeding2015
- Author(s)
  Majima Y, Kumamoto K, Takenoshita S, Shimomura K.
- Journal Title
  
  Brain Structure and Function
  
  Volume: ahead of print Issue: 9 Pages: 4723-4731
- DOI
  10.1007/s00429-015-1150-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461366
[Journal Article] Nasal oxytocin administration reduce food intake without affecting locomotor activity and glycemia with c-Fos induction in limited brain areas.2015
- Author(s)
  Maejima Y, Rita RS, Santoso P, Aoyama M, Hiraoka Y, Nishimori K, Gantulga D, Shimomura K, Yada T
- Journal Title
  
  Neuroendocrinology
  
  Volume: 101 Issue: 1 Pages: 35-44
- DOI
  10.1159/000371636
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591341, KAKENHI-PROJECT-26461366, KAKENHI-PROJECT-26670453, KAKENHI-PROJECT-15K09395, KAKENHI-PROJECT-15H02442
[Journal Article] Chronic phencyclidine treatment induces long-lasting glutamatergic activation of VTA dopamine neurons.2014
- Author(s)
  Uramura K, Maejima Y, Shimomura K, Santoso P, Katsuda S, Kobayashi D, Jodo E, Kodaira M, Otogon-Uul Z, Yang Y, Sakuma K, Takigawa M, Hazama A, Yada T
- Journal Title
  
  Neuroscience Letters
  
  Volume: 564 Pages: 72-77
- DOI
  10.1016/j.neulet.2014.01.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591341
[Journal Article] Chronic exposure to valproic acid promotes insulin release, reduces KATP channel current and does not affect Ca2+ signaling in mouse islets.2014
- Author(s)
  Kazunori Manaka
- Journal Title
  
  J Phys Sci
  
  Volume: 64 Issue: 1 Pages: 77-83
- DOI
  10.1007/s12576-013-0294-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591320, KAKENHI-PROJECT-24591341, KAKENHI-PROJECT-24592277, KAKENHI-PROJECT-24890218
[Journal Article] Chronic exposure to valproic acid promotes insulin release while reducing KATP channel current and unfaltering Ca^<2+> signaling in mouse islets2014
- Author(s)
  Manaka K, Nakata M, Shimomura K, Rita RS, Maejima Y, Yoshida M, Dezaki K, Kakei M, Yada T
- Journal Title
  
  Journal of Physiological Sciences
  
  Volume: 64 Pages: 77-83
- Data Source
  KAKENHI-PROJECT-24890218
[Journal Article] Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcute POMC neurons.2014
- Author(s)
  Maejima Y, Sakuma S, Santoso P, Gantulga D, Katsurada K, Ueta Y, Hiraoka Y, Nishimori K, Tanaka S, Shimomura K, Yada T
- Journal Title
  
  FEBS Letter
  
  Volume: 588 Issue: 23 Pages: 4404-4412
- DOI
  10.1016/j.febslet.2014.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23240057, KAKENHI-PROJECT-24591341, KAKENHI-PROJECT-26461366, KAKENHI-PROJECT-26670453
[Journal Article] Paraventricular nucleus nesfatin-1 neurons are regulated by pituitary adenylate cyclase-activating polypeptide (PACAP)2013
- Author(s)
  Maejima Y, Shimomura K, Sakuma K, Yang Y, Arai T, Mori M, Yada T
- Journal Title
  
  Neuroscience Letters
  
  Volume: 551 Pages: 39-42
- DOI
  10.1016/j.neulet.2013.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390044, KAKENHI-PROJECT-24591341
[Journal Article] Bupropion can close KATP channel and induce insulin secretion2013
- Author(s)
  Yang Y, Shimomura K, Sakuma K, Maejima Y, Iwasaki Y, Galvanovskis J, Dezaki K, Nakata M, Yada T
- Journal Title
  
  J Pediatr Endocrinol Metab
  
  Volume: 26(3-4) Issue: 3-4 Pages: 343-346
- DOI
  10.1515/jpem-2012-0295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390044, KAKENHI-PROJECT-23591320, KAKENHI-PROJECT-24591341, KAKENHI-PROJECT-24592277, KAKENHI-PROJECT-24659101, KAKENHI-PROJECT-24890218, KAKENHI-PUBLICLY-23115715, KAKENHI-PUBLICLY-23126523
[Journal Article] Bupropion can close KATP channel and induce insulin secretion2013
- Author(s)
  Yang Y, Shimomura K, Sakuma K, Maejima Y, Iwasaki Y, Galvanovskis J, Dezaki K, Nakata M, Yada T
- Journal Title
  
  J Pediatr Endocrinol Metab
  
  Volume: 26 Pages: 343-346
- Data Source
  KAKENHI-PROJECT-24890218
[Presentation] KATPチャネル異常によるＤＥＮＤ症候群における飲水障害2017
- Author(s)
  下村健寿
- Organizer
  小児科学会
- Place of Presentation
  高輪プリンスホテル
- Year and Date
  2017-04-15
- Data Source
  KAKENHI-PROJECT-26461366
[Presentation] 脳におけるKATPチャネルの活性化は摂食量の変化を伴わず飲水量を増加させる2013
- Author(s)
  下村健寿、楊怡飛、佐久間和哉、オトゴンウール・ゼセムドルジェ、プトラ・サントソ、前島裕子、矢田俊彦
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24890218
[Presentation] 抗肥満作用のある抗鬱剤ブプロピオンがインスリン分泌に与える影響2013
- Author(s)
  楊怡飛、前島裕子、佐久間和哉、オトゴンウール・ゼセムドルジェ、プトラ・サントソ、岩崎有作、下村健寿、矢田俊彦
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24890218
[Presentation] KATPチャネルとインスリン分泌　変異型チャネルの解析2013
- Author(s)
  下村健寿
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24890218
[Presentation] 新生児糖尿病モデルマウスにおける高血糖誘導はSU剤によって是正可能な摂食量亢進を促す2012
- Author(s)
  下村健寿
- Organizer
  第33回日本肥満学会
- Place of Presentation
  京都（ホテルグランビア京都）
- Data Source
  KAKENHI-PROJECT-24890218
[Presentation] 脳におけるKATPチャネルの活性化は摂食量の変化を伴わず飲水量を増加させる
- Author(s)
  下村健寿、ヨウ・イヒ、佐久間和哉、オトゴンウール・ゼセムドルジェ、プトラ・サントソ、前島裕子、矢田俊彦
- Organizer
  第34回日本肥満学会
- Data Source
  KAKENHI-PROJECT-24890218
[Presentation] 抗肥満作用のある抗鬱剤ブプロピオンがインスリン分泌に与える影響
- Author(s)
  ヨウ・イヒ、前島裕子、佐久間和哉、オトゴンウール・ゼセムドルジェ、プトラ・サントソ、岩崎有作、下村健寿、矢田俊彦
- Organizer
  第34回日本肥満学会
- Data Source
  KAKENHI-PROJECT-24890218

1. MAEJIMA Yuko (40438669)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. ITO Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. TAKAHASHI Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. SAKAMOTO Kazuho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. IWASAKI Yusaku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 兪志前

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 日出間志寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 矢田俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 深掘良二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 大野雄康

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 中田正範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 三木隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 鈴木弘行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 門馬智之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 西森克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimomura Kenju 下村 健寿

SHIMOMURA Kenju 下村 健寿

Research Projects

Research Products

Co-Researchers

脳KATPチャネル活性による認知症病態機序の解明と治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of KATP channel and insulin secretion by PIP2 and its application to diabetes treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of anti-obesity effect by recovery of endogenous oxytocin secretion and its clinical implication

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of brain KATP channel with pathology of sarcopenia and frailityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of development of oxytocinergic neutral circuit responding to energy status in childhood

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Contribution of KATP channel in PVN oxytocin neurons for food intake regulation.Principal Investigator

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Nesfatin-1

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Neuronal feature of neonatal diabetes and investigation of neuronal feature of KATP channel in brainPrincipal Investigator

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[Book] 最強の医師団が教える 長生きできる方法2020

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[Book] 神経内科 漢方薬からみた視床下部オキシトシンニューロンに対する作用2018

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[Journal Article] Systemic co-administration of low dose oxytocin and glucagon like peptide-1 additively decreases food intake and body weight2024

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[Journal Article] Dose Dependent Effect of Sulfamethoxazole on Inhibiting K<sub>ATP</sub> Channel of Mouse Pancreatic β Cell2023

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[Journal Article] Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion2023

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[Journal Article] Oxytocin Receptor-Expressing Neurons in the Medial Preoptic Area Are Essential for Lactation, whereas Those in the Lateral Septum Are Not Critical for Maternal Behavior2023

Shimomura Kenju 下村健寿

SHIMOMURA Kenju 下村健寿

[Book] 最強の医師団が教える長生きできる方法2020

[Book] 神経内科　漢方薬からみた視床下部オキシトシンニューロンに対する作用2018