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Arasaki Tomoko  新崎 智子

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新崎 智子  アラサキ トモコ

ARASAKI Tomoko  新崎 智子

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Researcher Number 90645855
Affiliation (Current) 2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 技術員
Affiliation (based on the past Project Information) *help 2019 – 2022: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 技術員
2014: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 技術員
Review Section/Research Field
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Applied health science
Keywords
Except Principal Investigator
記憶 / ホスホジエステラーぜ / バイオマーカー / 握力 / 遺伝子改変マウス / AMP / ERK / マウス / 老化 / 包括的行動解析 … More / 認知的フレイル / 炎症 / cAMP / シロスタゾール / フレイル / 注意 / 身体機能 / 認知機能 / 加齢 / 分散学習 / 休憩 / グアニル化 / 8-ニトロ-cGMP / 眼球運動 / 活性酸素種 / 一酸化窒素 / 小脳 / リハビリテーション / 学習 Less
  • Research Projects

    (2 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (3 People)
  •  Association of cognitive frailty and signal transduction disfunction.

    • Principal Investigator
      Endo Shogo
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Mechanisms underlying spacing effect of memory

    • Principal Investigator
      ENDO Shogo
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied health science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

All 2022 2021 2020 2019 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice2022

    • Author(s)
      Yanai Shuichi、Tago Tetsuro、Toyohara Jun、Arasaki Tomoko、Endo Shogo
    • Journal Title

      Frontiers in Pharmacology

      Volume: 13 Pages: 1031637-1031637

    • DOI

      10.3389/fphar.2022.1031637

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-22K11872, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
  • [Journal Article] Deficits in memory-guided limb movements impair obstacle avoidance locomotion in Alzheimer’s disease mouse model2014

    • Author(s)
      Setogawa S, Yamaura H, Arasaki T, Endo S, Yanagihara D
    • Journal Title

      Scientific Reports

      Volume: 4:7200 Issue: 1 Pages: 1-10

    • DOI

      10.1038/srep07220

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J09496, KAKENHI-PROJECT-25560295, KAKENHI-PROJECT-25560382, KAKENHI-PUBLICLY-26115532
  • [Presentation] Involvement of 8-nito-cGMP - ERK signals in the induction of long-term depression in the mouse cerebellum.2022

    • Author(s)
      S Kakizawa, T Arasaki, Yasushi Satoh, S Endo.
    • Organizer
      2022
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] ホスホジエステラーゼ3阻害剤シロスタゾールによる老化マウスの記憶機能低下の改善と予防2022

    • Author(s)
      柳井修一・新崎智子,遠藤昌吾
    • Organizer
      TOBIRA第10回研究交流フォーラム
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] Assessment of physical and cognitive frailty in aging mouse model. 22nd World Congress of Gerontology and Geriatrics2022

    • Author(s)
      S Yanai, T Arasaki & S Endo
    • Organizer
      22nd World Congress of Gerontology and Geriatrics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] Combined administration of donepezil and cilostazol ameliorates spatial memory impairment in APP knock-in mouse model for Alzheimer's disease.2022

    • Author(s)
      S Yanai, T Arasaki, T Saito, T Saido & S Endo.
    • Organizer
      第45回日本神経科学大会 (Neuro2022)
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] Involvement of 8-nitro-cGMP ? ERK signals in induction of long-term depression in the mouse cerebellum2022

    • Author(s)
      柿澤 昌、新崎 智子、佐藤 泰司、遠藤 昌吾
    • Organizer
      第95回日本薬理学会年会シンポジウム
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] Comparison of age-related multi-domain phenotype in human and mouse using comprehensive behavioral test battery.2021

    • Author(s)
      S Yanai, T Arasaki & S Endo
    • Organizer
      第44回日本神経科学大会 / CJK第1回国際会議
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] シロスタゾールとドネペジルの低用量併用による老齢マウスの記憶機能改善2021

    • Author(s)
      柳井修一, 新崎智子, 遠藤昌吾
    • Organizer
      日本心理学会第85回大会
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] MAP kinase:ERK1/2遺伝子改変マウスを用いた小脳依存性記憶の解析2020

    • Author(s)
      吉田彩乃、宮本武典、新崎智子、遠藤昌吾
    • Organizer
      第72回日本動物学会・関東支部大会
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] Concurrent administration of sub-effective doses of donepezil and phosphodiesterase 3 inhibitor cilostazol restores memory impairment in aged mice.2019

    • Author(s)
      Shuichi YANAI, Tomoko Arasaki, Shogo Endo
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] Cilostazol, a phosphodiesterase 3 inhibitor, improves blood-brain barrier integrity and ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8).2019

    • Author(s)
      S.Yanai, T.Arasaki & S.Endo
    • Organizer
      「次世代脳」プロジェクト 冬のシンポジウム
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] PDE3阻害剤シロスタゾールによる血液脳関門・記憶機能の改善2019

    • Author(s)
      柳井修一、新崎智子、遠藤昌吾
    • Organizer
      第8回 TOBIRA研究交流フォーラム
    • Data Source
      KAKENHI-PROJECT-19H04044
  • [Presentation] Distribution of 8-nitro-cGMP and S-guanylated proteins in cerebellum.2013

    • Author(s)
      S. Endo, M. Nakamura,T. Arasaki,T. Akaike
    • Organizer
      Japan Neuroscience Society
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-25560382
  • [Presentation] Cilostazol,a phosphodiesterase 3 inhibitor, improves memories in senescence accelerated mice.

    • Author(s)
      S. Yanai, T. Arasaki, and S. Endo.
    • Organizer
      Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25560382
  • [Presentation] Maintenance of memory functions by chronic administration of cilostazol, a phosphodiesterase 3 inhibitor, in aged mice models.

    • Author(s)
      Shuichi Yanai, Kai Kojima, Tomoko Arasaki & Shogo Endo
    • Organizer
      Annual meeting of Society for Neuroscience
    • Place of Presentation
      Washignton D.C., USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-25560382
  • [Presentation] Phosphodiesterase 3 inhibitor cilostazol improves conditioned fear in SAM-P8 mice.

    • Author(s)
      S. Yanai, K Kojima, T. Arasaki, and S. Endo.
    • Organizer
      Annual meeting of Japan Society for Biomedical Gerontology
    • Place of Presentation
      Obu, Aichi, Japan
    • Year and Date
      2014-07-26 – 2014-07-27
    • Data Source
      KAKENHI-PROJECT-25560382
  • 1.  ENDO Shogo (60192514)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 2.  YANAI Shuichi (60469070)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  TOYOHARA Jun
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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