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Minamihata Kosuke  南畑 孝介

ORCIDConnect your ORCID iD *help
Researcher Number 90648586
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2023: 九州大学, 工学研究院, 助教
2016 – 2019: 九州大学, 工学研究院, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 27040:Biofunction and bioprocess engineering-related / Transformative Research Areas, Section (II) / Bio-related chemistry
Except Principal Investigator
Basic Section 27040:Biofunction and bioprocess engineering-related / Biofunction/Bioprocess
Keywords
Principal Investigator
タンパク質ポリマー / 重合 / 無細胞タンパク質合成 / スクリーニング / ペプチド / 高発現システム / 受容体 / バキュロウイルス / カイコ / 難発現性 … More / 成長因子 / レセプター / タンパク質間相互作用 / インターロイキン / 遺伝子組換タンパク質 / サイトカイン / 細胞培養基材 / 細胞接着因子 / 細胞増殖因子 / ペルオキシダーゼ / ジスルフィド / 立体障害 / ジスルフィド結合 / 酵素反応 / 構造制御技術 / 機能性材料 / 集積 / タンパク質 / 検出プローブ / セルロソーム / 自己集合 / 複合化 / 蛋白質 / ポリマー … More
Except Principal Investigator
ワクチン / エマルション / ペプチド / 超分子 / アジュバント / ナノファーバータンパク質 / タンパク質性繊維素材 / SpyCatcher/SpyTag / タンパク質繊維素材 / タンパク質ポリマー / ナノファイバータンパク質 / がん治療 / 経皮吸収技術 / インフルエンザワクチン / がん免疫 / 感染症 / アレルギーワクチン / がんワクチン / ナノキャリア / 花粉症治療 / 感染症予防 / マラリア / インフルエンザ / 経皮吸収製剤 / イオン液体 / 花粉症ワクチン / 経皮免疫 / ナノ粒子 / 薬物キャリア / 経皮吸収 / DDS / 経皮ワクチン Less
  • Research Projects

    (7 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (8 People)
  •  Plural phenotype displaying peptide selection system for screening of peptides exhibiting synergistic interactionPrincipal Investigator

    • Principal Investigator
      南畑 孝介
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Kyushu University
  •  Development of vaccine adjuvant based on peptidic supramolecules loaded with antigenic proteins

    • Principal Investigator
      若林 里衣
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      Kyushu University
  •  Molecular spinning of nanofiber proteins

    • Principal Investigator
      Ishikawa Masahito
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
      Nagoya University
  •  evelopment of high-efficiency production and purification technology for useful proteins through masking of the interaction interface.Principal Investigator

    • Principal Investigator
      Minamihata Kosuke
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      Kyushu University
  •  Control of molecular structure of protein polymers and its application of creating novel cell growth factorsPrincipal Investigator

    • Principal Investigator
      Minamihata Kosuke
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      Kyushu University
  •  Establishment of molecular design guideline for hyperbrancked protein polymers and their use as scaffoldsPrincipal Investigator

    • Principal Investigator
      Minamihata Kosuke
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Bio-related chemistry
    • Research Institution
      Kyushu University
  •  Creation of Transdermal Drug Delivery Systems Using Solid-in-oil Nano-dispersion Technique

    • Principal Investigator
      Goto Masahiro
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Linear Polymerization of Protein by Sterically Controlled Enzymatic Cross-Linking with a Tyrosine-Containing Peptide Loop2020

    • Author(s)
      Permana Dani、Minamihata Kosuke、Sato Ryo、Wakabayashi Rie、Goto Masahiro、Kamiya Noriho
    • Journal Title

      ACS Omega

      Volume: 5 Issue: 10 Pages: 5160-5169

    • DOI

      10.1021/acsomega.9b04163

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H00841, KAKENHI-PROJECT-18K14067
  • [Journal Article] Genetically fused charged peptides induce rapid crystallization of proteins2020

    • Author(s)
      Kosuke Minamihata, Keisuke Tsukamoto, Motoyasu. Adachi, Rumi Shimizu, Masahiro Mishina, Ryota Kuroki, Teruyuki Nagamune
    • Journal Title

      Chemical Communications

      Volume: 56 Issue: 27 Pages: 3891-3894

    • DOI

      10.1039/c9cc09529b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Journal Article] Enzymatically Prepared Dual Functionalized Hydrogels with Gelatin and Heparin To Facilitate Cellular Attachment and Proliferation2019

    • Author(s)
      Ramadhan Wahyu、Kagawa Genki、Hamada Yusei、Moriyama Kousuke、Wakabayashi Rie、Minamihata Kosuke、Goto Masahiro、Kamiya Noriho
    • Journal Title

      ACS Applied Bio Materials

      Volume: 2 Issue: 6 Pages: 2600-2609

    • DOI

      10.1021/acsabm.9b00275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06369, KAKENHI-PROJECT-17K19016
  • [Journal Article] Polymerization of Horseradish Peroxidase by a Laccase‐Catalyzed Tyrosine Coupling Reaction2019

    • Author(s)
      Dani Permana, Kosuke Minamihata, Tsuneyuki Tatsuke, Jae M. Lee, Takahiro Kusakabe, Masahiro Goto, and Noriho Kamiya
    • Journal Title

      Biotechnology Journal

      Volume: in press Issue: 6 Pages: 1800531-1800531

    • DOI

      10.1002/biot.201800531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K14067, KAKENHI-PROJECT-16H04581
  • [Journal Article] Expression and Activation of Horseradish Peroxidase&-Protein A/G Fusion Protein in Silkworm Larvae for Diagnostic Purposes2018

    • Author(s)
      Patma, K. Minamihata, T. Tatsuke, J. M. Lee, T. Kusakabe, N. Kamiya
    • Journal Title

      Biotechnol. J.

      Volume: 印刷中 Pages: 1700624-1700624

    • DOI

      10.1002/biot.201700624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04581, KAKENHI-PROJECT-16K21008
  • [Journal Article] Mechanistic investigation of transcutaneous protein delivery using solid-in-oil nanodispersion: A case study with phycocyanin2018

    • Author(s)
      Hardiningtyas Safrina Dyah、Wakabayashi Rie、Kitaoka Momoko、Tahara Yoshiro、Minamihata Kosuke、Goto Masahiro、Kamiya Noriho
    • Journal Title

      European Journal of Pharmaceutics and Biopharmaceutics

      Volume: 127 Pages: 44-50

    • DOI

      10.1016/j.ejpb.2018.01.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Journal Article] Polymeric SpyCatcher Scaffold Enables Bioconjugation in a Ratio-Controllable Manner2017

    • Author(s)
      Jia Lili、Minamihata Kosuke、Ichinose Hirofumi、Tsumoto Kouhei、Kamiya Noriho
    • Journal Title

      Biotechnol. J.

      Volume: 12 Issue: 12 Pages: 1700195-1700195

    • DOI

      10.1002/biot.201700195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04581, KAKENHI-PROJECT-16K21008
  • [Presentation] Ultra-large artificial protein fiber formation via end-selective crosslinking of fibrous proteins2024

    • Author(s)
      Ayasa Nagatani, Kosuke Minamihata, Masahito Ishikawa, Shogo Yoshimoto, Katsutoshi Hori, Noriho Kamiya
    • Organizer
      ISBC2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H01727
  • [Presentation] 人工タンパク質繊維に向けた繊維状タンパク質重合反応の基礎検討2023

    • Author(s)
      長谷彩沙、南畑孝介、石川聖人、吉本将悟、堀克敏、神谷典穂
    • Organizer
      化学工学会 第54回秋季大会
    • Data Source
      KAKENHI-PROJECT-21H01727
  • [Presentation] 繊維状タンパク質の両末端連結反応を基盤とした人工繊維の形成2023

    • Author(s)
      長谷彩沙、南畑孝介、石川聖人、吉本将悟、堀克敏、神谷典穂
    • Organizer
      第75回日本生物工学会大会
    • Data Source
      KAKENHI-PROJECT-21H01727
  • [Presentation] Hybrid protein crystal formation mediated by the interaction of positively charged peptide tags and oligo ssDNAs2023

    • Author(s)
      長谷彩沙、南畑孝介、若林里衣、後藤雅宏、神谷典穂
    • Organizer
      The 34th International Symposium on Chemical Engineering
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K23152
  • [Presentation] 経皮マラリアワクチンの開発および経皮投与による免疫応答解析2022

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      化学工学会第87年会,
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] Development of transdermal malaria vaccine2021

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      The 26th Symposium of Young Asian Biological Engineers’ Community(YABEC2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] Transdermal Formulation of Malaria Vaccine Using Solid-in-Oil Technology2021

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      膜シンポジウム2021
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] がんペプチド抗原を提示したポリマー型キャリアタンパク質の開発2021

    • Author(s)
      上野利晃・南畑 孝介・ 若林 里衣・神谷 典穂・後藤 雅宏
    • Organizer
      化学工学会第52回秋季大会
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] Solid-in-Oil化技術の経皮マラリアワクチンへの応用2021

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      化学工学会第52回秋季大会
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] Solid-in-Oil化技術を利用した経皮マラリアワクチンの創製2021

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      第58回化学関連支部合同九州大会
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] タンパク質油中分散化技術を用いた経皮マラリアワクチンの創製2021

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      第15回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] Solid-in-Oil化技術を用いたマラリアワクチンの経皮製剤化2021

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      第31回九州地区若手ケミカルエンジニア討論会
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] 伝搬阻止抗原を用いた経皮マラリアワクチンの創製2021

    • Author(s)
      田中敬佑、南畑孝介、若林里衣、神谷典穂、後藤雅宏
    • Organizer
      第37回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06369
  • [Presentation] 分子クラウディング環境下における酵素触媒を介したタンパク質集合化挙動2020

    • Author(s)
      佐藤 崚, 南畑 孝介, 後藤 雅宏, 神谷 典穂
    • Organizer
      化学工学会第85年会
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Presentation] Formation of Linear Protein Polymer by Controlling Enzymatic Cross-linking Reaction with a Tyrosine-containing Loop Peptide.2020

    • Author(s)
      D. Permana, K. Minamihata, R. Sato, R. Wakabayashi, M. Goto, N. Kamiya
    • Organizer
      he 12th Asian Federation of Biotechnology (AFOB) Regional Symposium 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Presentation] タンパク質の片末端集合化を可能にするPolyTagの機能性評価2019

    • Author(s)
      佐藤 崚, 南畑 孝介, 後藤 雅宏, 神谷 典穂
    • Organizer
      2019年度生物工学若手研究者の集い
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Presentation] 組成制御が可能な異種タンパク質集合体調整法の開発2019

    • Author(s)
      佐藤 崚, 南畑 孝介, 後藤 雅宏, 神谷 典穂
    • Organizer
      酵素工学研究会 第82回講演会
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Presentation] 酵素触媒によるペプチドタグを起点としたタンパク質ポリマー形成2019

    • Author(s)
      佐藤崚, 南畑孝介, 後藤雅宏, 神谷典穂
    • Organizer
      化学工学会第84年会
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Presentation] 酵素触媒によるペプチドタグ特異的な異種タンパク質の集合化2019

    • Author(s)
      佐藤 崚, 南畑 孝介, 後藤 雅宏, 神谷 典穂
    • Organizer
      第13回バイオ関連化学シンポジウム2019
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Presentation] Single peptide-tag specific assembly of functional proteins by enzymatic crosslinking reaction2019

    • Author(s)
      R. Sato, K. Minamihata, M. Goto, N. Kamiya
    • Organizer
      The 32nd International symposium on Chemical Engineering
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14067
  • [Presentation] ペルオキシダーゼ酵素反応を利用したタンパク質ポリマーの創製とその応用に関する研究2017

    • Author(s)
      南畑孝介
    • Organizer
      酵素工学研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K21008
  • [Presentation] Functionalization of magnetic nanoparticles with protein polymer.2016

    • Author(s)
      Lili Jia, Kosuke Minamihata, Hirofumi Ichinose and Noriho Kamiya
    • Organizer
      22nd Young Asian Biochemical Engineers’ Community 2016 (YABEC 2016)
    • Place of Presentation
      Phoenix Seagaia Resort, Miyazaki, Japan.
    • Year and Date
      2016-10-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21008
  • [Presentation] ペプチドタグで作るタンパク質の集合体2016

    • Author(s)
      南畑孝介
    • Organizer
      材料化学システム工学討論会2016
    • Place of Presentation
      東京大学
    • Year and Date
      2016-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K21008
  • 1.  神谷 典穂 (50302766)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 18 results
  • 2.  若林 里衣 (60595148)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 3.  Goto Masahiro (10211921)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 4.  Ishikawa Masahito (70750602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  田原 義朗 (30638383)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  堀 克敏 (50302956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  Patmawati Lili Jia
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KUSAKABE Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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