Watanabe Takao 渡辺崇夫

Researcher Number	90650458
Other IDs
Affiliation (Current)	2025: 愛媛大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2024: 愛媛大学, 医学系研究科, 講師 2019 – 2022: 愛媛大学, 医学系研究科, 講師 2016 – 2018: 愛媛大学, 医学部附属病院, 講師 2017: 愛媛大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator 肝細胞癌 / PKR / 代謝 / 細胞増殖 / NASH / 阻害剤 / メチル化 / HCV / 肝線維化 / 結合蛋白質 … More / 解糖系 / 代謝経路 / 増殖因子 / 血管新生 / イメージング / 治療標的 / C型肝炎ウイルス / proliferation / PKR inhibitor / DNA methylation / hepatocellular carcinoma Less

PKR結合蛋白質複合体による新規肝細胞癌制御のメカニズムの解明と治療法の開発Principal Investigator
- Principal Investigator
  
  渡辺崇夫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Ehime University
The role of PKR in hepatocellular carcinoma associated with intracellular metabolismPrincipal Investigator
- Principal Investigator
  
  Watanabe Takao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Ehime University
The inhibitor of protein kinase R (PKR) suppresses tumor proliferation and angiogenesis in hepatocellular carcinoma in vitro and in vivo modelsPrincipal Investigator
- Principal Investigator
  
  Watanabe Takao
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Ehime University
The study to clarify the tumor suppressive effect of PKR inhibitor in hepatocellular carcinoma using in vivo imagingPrincipal Investigator
- Principal Investigator
  
  Watanabe Takao
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Ehime University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Role of B Cell-Activating Factor in Fibrosis Progression in a Murine Model of Non-Alcoholic Steatohepatitis2023
- Author(s)
  Kozue Kanemitsu-Okada, Masanori Abe, Yoshiko Nakamura, Teruki Miyake, Takao Watanabe, Osamu Yoshida, Yohei Koizumi, Masashi Hirooka, Yoshio Tokumoto, Bunzo Matsuura, Mitsuhito Koizumi, Yoichi Hiasa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 3 Pages: 2509-2509
- DOI
  10.3390/ijms24032509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11804, KAKENHI-PROJECT-22K11855, KAKENHI-PROJECT-20K08388, KAKENHI-PROJECT-20K16991, KAKENHI-PROJECT-23K15072
[Journal Article] Spleen stiffness in patients with chronic liver disease evaluated by 2-D shear wave elastography with ultrasound multiparametric imaging2023
- Author(s)
  Hirooka M, Koizumi Y, Nakamura Y, Yano R, Okazaki Y, Sunago K, Imai Y, Watanabe T, Yoshida O, Tokumoto Y, Abe M, Hiasa Y.
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 2 Pages: 93-103
- DOI
  10.1111/hepr.13841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08388
[Journal Article] Additional Effect of Luseogliflozin on Semaglutide in Nonalcoholic Steatohepatitis Complicated by Type 2 Diabetes Mellitus: An Open-Label, Randomized, Parallel-Group Study2022
- Author(s)
  Miyake T, Yoshida O, Matsuura B, Furukawa S, Hirooka M, Abe M, Tokumoto Y, Koizumi Y, Watanabe T, Takeshita E, Sunago K, Yukimoto A, Watanabe K, Miyazaki M, Kanzaki S, Nakaguchi H, Koizumu M, Yamamoto Y, Kumagi T, Hiasa Y.
- Journal Title
  
  Diabetes Therapy
  
  Volume: 13 Issue: 5 Pages: 1083-1096
- DOI
  10.1007/s13300-022-01239-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08388
[Journal Article] Cisterna chyli as an optimal marker of tolvaptan response in severe cirrhotic ascites2022
- Author(s)
  Hirooka M, Koizumi Y, Yano R, Nakamura Y, Sunago K, Yukimoto A, Watanabe T, Yoshida O, Tokumoto Y, Abe M, Hiasa Y.
- Journal Title
  
  Scientic Reports
  
  Volume: 17 Issue: 1 Pages: 8124-8124
- DOI
  10.1038/s41598-022-11889-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08388
[Journal Article] Plasma Fatty Acid Composition Is Associated with Histological Findings of Nonalcoholic Steatohepatitis2022
- Author(s)
  Teruki Miyake, Shinya Furukawa, Bunzo Matsuura, Osamu Yoshida, Masumi Miyazaki, Akihito Shiomi, Sayaka Kanzaki, Hironobu Nakaguchi, Kotaro Sunago, Yoshiko Nakamura, Yusuke Imai, Takao Watanabe, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Teru Kumagi, Masanori Abe, Yoichi Hiasa
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 10 Pages: 2540-2540
- DOI
  10.3390/biomedicines10102540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11804, KAKENHI-PROJECT-20K08333, KAKENHI-PROJECT-20K08388
[Journal Article] Direct-acting antivirals improve survival and recurrence rates after treatment of hepatocellular carcinoma within the Milan criteria2021
- Author(s)
  Ochi H, Hiraoka A, Hirooka M, Koizumi Y, Amano M, Azemoto N, Watanabe T, Yoshida O, Tokumoto Y, Mashiba T, Yokota T, Abe M, Michitaka K, Hiasa Y, Joko K.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 1 Pages: 90-100
- DOI
  10.1007/s00535-020-01747-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08388
[Journal Article] The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells2021
- Author(s)
  Yukimoto Atsushi、Watanabe Takao、Sunago Kotaro、Nakamura Yoshiko、Tanaka Takaaki、Koizumi Yohei、Yoshida Osamu、Tokumoto Yoshio、Hirooka Masashi、Abe Masanori、Hiasa Yoichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 7926-7926
- DOI
  10.1038/s41598-021-86592-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08007, KAKENHI-PROJECT-20K08388, KAKENHI-PROJECT-21K08008
[Journal Article] AFP and eGFR are related to early and late recurrence of HCC following antiviral therapy.2021
- Author(s)
  Watanabe T, Tokumoto Y, Joko K, Michitaka K, Horiike N, Tanaka Y, Tada F, Kisaka Y, Nakanishi S, Yamauchi K, Ochi H, Hiraoka A, Yagi S, Yukimoto A, Hirooka M, Abe M, Hiasa Y
- Journal Title
  
  BMC Cancer
  
  Volume: 14;21(1) Issue: 1 Pages: 699-699
- DOI
  10.1186/s12885-021-08401-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08388, KAKENHI-PROJECT-21K08008
[Journal Article] Validation of the FibroScan-aspartate aminotransferase score by vibration-controlled transient and B-mode ultrasound elastography.2021
- Author(s)
  Hirooka M, Koizumi Y, Yano R, Sunago K, Watanabe T, Yoshida O, Tokumoto Y, Abe M, Hiasa Y.
- Journal Title
  
  Hepatology Research
  
  Volume: 51(6) Issue: 6 Pages: 652-661
- DOI
  10.1111/hepr.13646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08388
[Journal Article] Apoptosis-associated speck-like protein containing a CARD regulates the growth of pancreatic ductal adenocarcinoma2021
- Author(s)
  Koizumi Mitsuhito、Watanabe Takao、Masumoto Junya、Sunago Kotaro、Imamura Yoshiki、Kanemitsu Kozue、Kumagi Teru、Hiasa Yoichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 22351-22351
- DOI
  10.1038/s41598-021-01465-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07469, KAKENHI-PROJECT-20K08388
[Journal Article] Relationship between body composition and the histology of non‐alcoholic fatty liver disease: a cross‐sectional study2021
- Author(s)
  Miyake Teruki、Miyazaki Masumi、Yoshida Osamu、Kanzaki Sayaka、Nakaguchi Hironobu、Nakamura Yoshiko、Watanabe Takao、Yamamoto Yasunori、Koizumi Yohei、Tokumoto Yoshio、Hirooka Masashi、Furukawa Shinya、Takeshita Eiji、Kumagi Teru、Ikeda Yoshio、Abe Masanori、Toshimitsu Kumiko、Matsuura Bunzo、Hiasa Yoichi
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 21 Issue: 1 Pages: 170-170
- DOI
  10.1186/s12876-021-01748-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11743, KAKENHI-PROJECT-18K07469, KAKENHI-PROJECT-20K08333, KAKENHI-PROJECT-20K08388
[Journal Article] Sex difference in the development of hepatocellular carcinoma after direct-acting antiviral therapy in patients with HCV infection. J Med Virol.2020
- Author(s)
  Watanabe T, Tokumoto Y, Joko K, Michitaka K, Horiike N, Tanaka Y, Tada F, Kisaka Y, Nakanishi S, Yamauchi K, Yukimoto A, Nakamura Y, Hirooka M, Abe M, Hiasa Y
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 92 Issue: 12 Pages: 3507-3515
- DOI
  10.1002/jmv.25984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08388
[Journal Article] Therapeutic Effects of the PKR Inhibitor C16 Suppressing Tumor Proliferation and Angiogenesis in Hepatocellular Carcinoma in Vitro and in Vivo.2020
- Author(s)
  Watanabe T, Ninomiya H, Saitou T, Takanezawa S, Yamamoto S, Imai Y, Yoshida O, Kawakami R, Hirooka M, Abe M, Imamura T, Hiasa Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 20;10(1) Issue: 1 Pages: 5133-5133
- DOI
  10.1038/s41598-020-61579-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15818, KAKENHI-PROJECT-18K08007
[Journal Article] Advanced fibrosis of non-alcoholic steatohepatitis affects the significance of lipoprotein(a) as a cardiovascular risk factor2020
- Author(s)
  Konishi K, Miyake T, Furukawa S, Senba H, Kanzaki S, Nakaguchi H, Yukimoto A, Nakamura Y, Watanabe T, Koizumi Y, Yoshida O, Tokumoto Y, Hirooka M, Kumagi T, Abe M, Matsuura B, Hiasa Y.
- Journal Title
  
  Atherosclerosis
  
  Volume: 299 Pages: 32-37
- DOI
  10.1016/j.atherosclerosis.2020.02.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11743, KAKENHI-PROJECT-18K15818, KAKENHI-PROJECT-18K07469, KAKENHI-PROJECT-20K08333, KAKENHI-PROJECT-20K08388, KAKENHI-PROJECT-18K07911, KAKENHI-PROJECT-18K08007
[Journal Article] Predictors of hepatocellular carcinoma occurrence after direct-acting antiviral therapy in patients with hepatitis C virus infection.2019
- Author(s)
  Watanabe T, Tokumoto Y, Joko K, Michitaka K, Horiike N, Tanaka Y, Tada F, Kisaka Y, Nakanishi S, Yamauchi K, Yukimoto A, Hirooka M, Abe M, Hiasa Y.
- Journal Title
  
  Hepatology Research
  
  Volume: Feb;49(2) Issue: 2 Pages: 136-146
- DOI
  10.1111/hepr.13278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15818
[Journal Article] Stimulated hepatic stellate cell promotes progression of hepatocellular carcinoma due to protein kinase R activation2019
- Author(s)
  Imai Y, Yoshida O, Watanabe T, Yukimoto A, Koizumi Y, Ikeda Y, Tokumoto Y, Hirooka M, Abe M, Hiasa Y
- Journal Title
  
  PLos One
  
  Volume: 14 Issue: 2 Pages: e0212589-e0212589
- DOI
  10.1371/journal.pone.0212589
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07911, KAKENHI-PROJECT-18K08007, KAKENHI-PROJECT-18K15818, KAKENHI-PROJECT-17K15952
[Journal Article] Using ALBI score at the start of sorafenib treatment to predict regorafenib treatment candidates in patients with hepatocellular carcinoma.2019
- Author(s)
  Yukimoto A, Hirooka M, Hiraoka A, Michitaka K, Ochi H, Joko K, Imai Y, Watanabe T, Koizumi Y, Yoshida O, Abe M, Hiasa Y.
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: Jan 1;49(1) Issue: 1 Pages: 42-47
- DOI
  10.1093/jjco/hyy153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15818
[Journal Article] Roles of protein kinase R in cancer: Potential as a therapeutic target.2018
- Author(s)
  Watanabe T, Imamura T, Hiasa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 4 Pages: 919-925
- DOI
  10.1111/cas.13551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-16K19349, KAKENHI-PROJECT-18K08007, KAKENHI-PROJECT-18K15818, KAKENHI-PLANNED-15H05952, KAKENHI-PROJECT-16H06280
[Journal Article] Predictors of treatment efficacy and ALT non-normalization with sofosbuvir/ribavirin therapy for patients with hepatitis C virus genotype 2.2017
- Author(s)
  Watanabe T, Tokumoto Y, Joko K, Michitaka K, Horiike N, Tanaka Y, Tada F, Kisaka Y, Nakanishi S, Nonaka T, Yamauchi K, Hirooka M, Abe M, Hiasa Y.
- Journal Title
  
  J Med Virol.
  
  Volume: 89 Issue: 9 Pages: 1567-1573
- DOI
  10.1002/jmv.24776
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-16K19349
[Journal Article] Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma.2017
- Author(s)
  Ohno Y, Koizumi M, Nakayama H, Watanabe T, Hirooka M, Tokumoto Y, Kuroda T, Abe M, Fukuda S, Higashiyama S, Kumagi T, Hiasa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 5 Pages: 0177343-0177343
- DOI
  10.1371/journal.pone.0177343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-16K19349, KAKENHI-PROJECT-16K19350, KAKENHI-PROJECT-16K20013
[Presentation] A simple and accurate prediction model of hepatocellular carcinoma occurrence after DAA therapy using the factors at SVR122022
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Makoto Morita, Ryo Yano, Yuki Okazaki, Kotaro Sunago, Yoshiko Nakamura, Yusuke Imai, Yohei Koizumi, Osamu Yoshida, Masashi Hirooka, Masanori Abe, and Yoichi Hiasa
- Organizer
  AASLD the liver meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] SVR後の食道胃静脈瘤増悪に寄与する因子の検討2022
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] 年齢層に応じたSVR後肝発癌危険因子の検討2022
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第26回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] SVR後の食道胃静脈瘤増悪・改善を予測可能なスコアリングシステムの作成2022
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] SVR後の食道胃静脈瘤増悪を予測する因子の検討2021
- Author(s)
  渡辺崇夫、徳本良雄、上甲康二、道堯浩二郎、堀池典生、田中良憲、木阪吉保、多田藤政、中西征司、八木専、山内一彦、廣岡昌史、阿部雅則、日浅陽一
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] Sex-related Differences in Predictors of HCC Incidence after DAA Therapy in Patients with HCV2021
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Atsushi Yukimoto, Yoshiko Nakamura, Yuki Okazaki, Kotaro Sunago, Yohei Koizumi, Osamu Yoshida, Masashi Hirooka, Masanori Abe, Yoichi Hiasa
- Organizer
  APASL Oncology 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] SVR後の肝癌サーベイランス法の検証2021
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第24回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] 小胞体ストレスに関連する long noncoding RNA RMRP を介した肝細胞がんのアポトーシス誘導作用2021
- Author(s)
  行本敦，渡辺崇夫，日浅陽一
- Organizer
  第44回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] Predictors of hepatocellular carcinoma recurrence after direct-acting antiviral therapy in patients with HCV infection2021
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Atsushi Yukimoto, Yuki Okazaki, Kotaro Sunago, Yohei Koizumi, Osamu Yoshida, Masashi Hirooka, Masanori Abe, Yoichi Hiasa
- Organizer
  JSH International Liver Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] 肝細胞癌におけるprotein kinase R (PKR)の治療標的としての可能性2020
- Author(s)
  渡辺崇夫、二宮寛子、齋藤卓、川村良介、小泉光仁、吉田理、徳本良雄、廣岡昌史、阿部雅則、今村健志、日浅陽一
- Organizer
  第79回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] 肝細胞癌における Protein kinase R (PKR)の役割と、治療標的としての可能性2020
- Author(s)
  渡辺崇夫、今村健志、日浅陽一
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] 肝細胞癌におけるProtein kinase R (PKR)の組織バイオマーカーとしての役割と標的治療の可能性2020
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] SOF/VEL治療における肝予備能評価指数の変化と改善を予測する因子の検討2020
- Author(s)
  渡辺崇夫、真柴寿枝、上甲康二、道堯浩二郎、徳本良雄、日浅陽一
- Organizer
  第24回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] DAA治療後の時期に応じた肝細胞癌再発寄与因子の検討2020
- Author(s)
  渡辺崇夫、上甲康二、道堯浩二郎、堀池典生、田中良憲、多田藤政、木阪吉保、中西征司、山内一彦、徳本良雄、日浅陽一
- Organizer
  第62回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-20K08388
[Presentation] 多施設共同研究における超高齢者C型肝炎患者に対するDAA治療の治療効果・安全性の検討2019
- Author(s)
  渡辺崇夫、上甲康二、道堯浩二郎、堀池典生、田中良憲、多田藤政、上杉和寛、中西征司、野中卓、山内一彦、廣岡昌史、阿部雅則、日浅陽一
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K15818
[Presentation] 多施設共同研究によるC型肝炎に対するDAA治療後の肝細胞癌新規発症危険因子における性別の影響についての検討2019
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第43回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-18K15818
[Presentation] 多施設共同研究によるDAA治療後の肝細胞癌新規発症, 再発例の特徴についての解析2019
- Author(s)
  渡辺崇夫, 道堯浩二郎, 日浅陽一
- Organizer
  第55回日本肝臓学会総会プログラム
- Data Source
  KAKENHI-PROJECT-18K15818
[Presentation] 当科における肝硬変の成因別分類2018
- Author(s)
  渡辺崇夫、行本敦、今井祐輔、中村由子、小泉洋平、吉田理、廣岡昌史、阿部雅則、日浅陽一
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K15818
[Presentation] DAAによるSVR後のHCV関連肝発がんに寄与する臨床因子の検討2018
- Author(s)
  廣岡昌史、渡辺崇夫、日浅陽一
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K15818
[Presentation] C型肝炎に対するDAA治療後の肝細胞癌新規発症危険群の同定2018
- Author(s)
  渡辺崇夫、上甲康二、日浅陽一
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-18K15818
[Presentation] DAA治療後のALT値から見たSVR後肝発癌高危険群の検討2017
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-16K19349
[Presentation] C型肝炎に対するDAA治療後の肝細胞癌新規発症・再発に寄与する因子の検討2017
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第21回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K19349
[Presentation] The epigenetic roles of protein kinase R in hepatocellular carcinoma with hepatitis C virus Infection, and possibility of PKR inhibitor as a therapeutic target2017
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Masashi Hirooka, Osamu Yoshida, Yohei Koizumi, Yusuke Imai, Yoshiko Nakamura, Masanori Abe1, Hiroko Ninomiya, Takeshi Imamura, Yoichi Hiasa
- Organizer
  The asian pacific association for the study of the liver single topic conference in Nagasaki
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19349
[Presentation] C型肝炎に対するDAA治療後の肝細胞癌新規発症・再発に関する検討2017
- Author(s)
  渡辺崇夫、徳本良雄、日浅陽一
- Organizer
  第53回日本肝臓学会総会プログラム
- Data Source
  KAKENHI-PROJECT-16K19349
[Presentation] The roles of Protein kinase R and its possibility as a therapeutic target in hepatocellular carcinoma with hepatitis C virus infection2016
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Masashi Hirooka, Osamu Yoshida, Yohei Koizumi, Yusuke Imai, Yoshiko Nakamura, Masanori Abe, Yoichi Hiasa
- Organizer
  AALSD the liver meeting 2016
- Place of Presentation
  ボストン (アメリカ合衆国)
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19349
[Presentation] Overexpresssed protein kinase R (PKR) in hepatocellular carcinoma with HCV infection modurates DNA methylation2016
- Author(s)
  Takao Watanabe, Yoshio Tokumoto, Masashi Hirooka, Osamu Yoshida, Yohei Koizumi, Yusuke Imai, Yoshiko Nakamura, Masanori Abe, Yoichi Hiasa
- Organizer
  HCV2016
- Place of Presentation
  京都国際会議場 (京都府京都市)
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19349

1. 日浅陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 三宅映己

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
3. 阿部雅則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 熊木天児

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Takao 渡辺 崇夫

Research Projects

Research Products

Co-Researchers

PKR結合蛋白質複合体による新規肝細胞癌制御のメカニズムの解明と治療法の開発Principal Investigator

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The role of PKR in hepatocellular carcinoma associated with intracellular metabolismPrincipal Investigator

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The inhibitor of protein kinase R (PKR) suppresses tumor proliferation and angiogenesis in hepatocellular carcinoma in vitro and in vivo modelsPrincipal Investigator

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The study to clarify the tumor suppressive effect of PKR inhibitor in hepatocellular carcinoma using in vivo imagingPrincipal Investigator

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[Journal Article] Role of B Cell-Activating Factor in Fibrosis Progression in a Murine Model of Non-Alcoholic Steatohepatitis2023

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[Journal Article] Spleen stiffness in patients with chronic liver disease evaluated by 2-D shear wave elastography with ultrasound multiparametric imaging2023

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[Journal Article] Additional Effect of Luseogliflozin on Semaglutide in Nonalcoholic Steatohepatitis Complicated by Type 2 Diabetes Mellitus: An Open-Label, Randomized, Parallel-Group Study2022

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[Journal Article] Cisterna chyli as an optimal marker of tolvaptan response in severe cirrhotic ascites2022

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[Journal Article] Plasma Fatty Acid Composition Is Associated with Histological Findings of Nonalcoholic Steatohepatitis2022

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[Journal Article] Direct-acting antivirals improve survival and recurrence rates after treatment of hepatocellular carcinoma within the Milan criteria2021

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[Journal Article] The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells2021

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[Journal Article] AFP and eGFR are related to early and late recurrence of HCC following antiviral therapy.2021

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[Journal Article] Validation of the FibroScan-aspartate aminotransferase score by vibration-controlled transient and B-mode ultrasound elastography.2021

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[Journal Article] Apoptosis-associated speck-like protein containing a CARD regulates the growth of pancreatic ductal adenocarcinoma2021

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[Journal Article] Relationship between body composition and the histology of non‐alcoholic fatty liver disease: a cross‐sectional study2021

Author(s)

Watanabe Takao 渡辺崇夫