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Magi Shigeyuki  間木 重行

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MAGI Shigeyuki  間木 重行

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Researcher Number 90708546
Other IDs
Affiliation (Current) 2025: 東邦大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2019 – 2023: 東邦大学, 医学部, 助教
2018: 大阪大学, 蛋白質研究所, 助教
2017: 大阪大学, たんぱく質研究所, 助教
Review Section/Research Field
Principal Investigator
Basic Section 90110:Biomedical engineering-related / Basic Section 43060:System genome science-related / Complex systems / System genome science
Keywords
Principal Investigator
心筋細胞 / 数理モデル / がん / 一細胞解析 / 薬剤耐性 / 乳がん / 薬物探索 / 人工知能 / モーションベクトル / 深層学習 … More / 心毒性 / 抗癌薬 / がん治療関連心筋障害 / 乳がん細胞 / HER2 / 細胞内シグナル伝達 / シグナル伝達 / がん細胞 / HER2シグナル / オートファジー / 抗がん剤耐性 / モデル化とシミュレーション / がん細胞の特性 / 1細胞解析 Less
  • Research Projects

    (4 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (2 People)
  •  Drug screening against anticancer drug-induced cardiac dysfunction with artificial intelligence learning motion vectorsPrincipal Investigator

    • Principal Investigator
      間木 重行
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Toho University
  •  Integrated Mathematical Analysis of Anticancer and Cardiac Hypofunction Effects of HER2 InhibitorsPrincipal Investigator

    • Principal Investigator
      Magi Shigeyuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43060:System genome science-related
    • Research Institution
      Toho University
  •  オートファジーが関与する抗がん剤耐性獲得過程の数理モデル解析Principal Investigator

    • Principal Investigator
      間木 重行
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Toho University
  •  Understanding heterogeneity within cell population in the process of acquiring anti-cancer drug resistancePrincipal Investigator

    • Principal Investigator
      MAGI Shigeyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      System genome science
    • Research Institution
      Toho University
      Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] A combination approach of pseudotime analysis and mathematical modeling for understanding drug-resistant mechanisms.2021

    • Author(s)
      Shigeyuki Magi, Sewon Ki, Masao Ukai, Elisa Dominguez-Huettinger, Atsuhiko Naito, Yutaka Suzuki, Mariko Okada.
    • Journal Title

      Sci Rep

      Volume: 11 Issue: 1 Pages: 18511-18511

    • DOI

      10.1038/s41598-021-97887-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04031, KAKENHI-PROJECT-20K15782
  • [Journal Article] Mathematical Modeling and Transcriptome Profiling of Breast Cancer Cells During Tamoxifen Treatment Reveal Multiple Trajectories for Resistant Subtypes2021

    • Author(s)
      Magi Shigeyuki、Ki Sewon、Ukai Masao、Naito Atsuhiko、Suzuki Yutaka、Okada Mariko
    • Journal Title

      Research Square

      Volume: -

    • DOI

      10.21203/rs.3.rs-136924/v1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06302, KAKENHI-PUBLICLY-19H04963, KAKENHI-PROJECT-18H04031
  • [Presentation] 心筋細胞と人工知能による心機能障害スクリーニングシステムの開発2024

    • Author(s)
      間木重行, 内藤篤彦
    • Organizer
      第20回 東邦大学5学部合同学術集会
    • Data Source
      KAKENHI-PROJECT-23K11813
  • [Presentation] Development of a screening system for cardiac dysfunction using a deep learning model with motion vectors of cardiomyocytes2023

    • Author(s)
      間木重行, 内藤篤彦
    • Organizer
      2023年日本バイオインフォマティクス学会年会 第12回生命医薬情報学連合大会(IIBMP2023)
    • Data Source
      KAKENHI-PROJECT-23K11813
  • [Presentation] がん薬物療法の耐性・心機能低下克服に挑む生命情報学研究2022

    • Author(s)
      間木重行
    • Organizer
      宮崎大学生命情報学勉強会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K15782
  • [Presentation] Systems biological approaches to understand the mechanisms of cancer drug resistance & cardiotoxicity2020

    • Author(s)
      Shigeyuki Magi, Atsuhiko Naito
    • Organizer
      情報計算化学生物学会
    • Data Source
      KAKENHI-PROJECT-20K15782
  • [Presentation] Systems biological approaches to understand the mechanisms of cancer drug resistance & cardiotoxicity2020

    • Author(s)
      Shigeyuki Magi, Atsuhiko Naito
    • Organizer
      情報計算化学生物学会
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] がん薬物療法の耐性・心機能障害克服に挑む数理モデル研究2020

    • Author(s)
      間木重行、内藤篤彦
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K15782
  • [Presentation] オートファジーが関与する抗がん剤耐性獲得過程の数理モデル解析2020

    • Author(s)
      間木重行
    • Organizer
      令和2年 「数理シグナル」 領域推進会議
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] がん薬物療法の耐性・心機能障害克服に挑む数理モデル研究2020

    • Author(s)
      間木重行, 内藤篤彦
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] A hybrid mathematical model for design and optimization of tamoxifen treatment in MCF-7 breast cancer cells2019

    • Author(s)
      Dominguez-Huttinger E, Magi S, AntoniA A, Ortiz O, Ramirez A.R., Okada M
    • Organizer
      The 20th International Conference on Systems Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] 時系列・一細胞解析による抗がん剤耐性獲得過程の理解2019

    • Author(s)
      間木重行, 奇 世媛, 鵜飼正雄, 鈴木 穣, 岡田眞里子
    • Organizer
      日本バイオインフォマティクス学会 2019年年会・ 第8回生命医薬情報学連合大会
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] 時系列・一細胞解析による抗がん剤耐性獲得過程の理解2019

    • Author(s)
      間木 重行
    • Organizer
      新学術領域研究「数理シグナル」 第3回 若手ワークショップ
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] A NF-κB - p38 MAPK crosstalk shapes oscillatory gene expression2019

    • Author(s)
      Michida H, Ando M, Magi S, Okada M
    • Organizer
      The 20th International Conference of Systems Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] オートファジーが関与する抗がん剤耐性獲得過程の数理モデル解析2019

    • Author(s)
      間木 重行
    • Organizer
      令和元年 「数理シグナル」 領域推進会議
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] A comprehensive model of heterogeneous cell cycle responses2019

    • Author(s)
      Imoto H, Ebata K, Magi S, Zhang S, Okada M
    • Organizer
      The 57th Annual Meeting of the Biophysical Society of Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] A NF-κB - p38 MAPK crosstalk shapes oscillatory gene expression2019

    • Author(s)
      Michida H, Ando M, Magi S, Okada M
    • Organizer
      The 20th International Conference of Systems Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] 時系列・一細胞解析から見える抗がん剤耐性獲得過程2019

    • Author(s)
      間木 重行
    • Organizer
      大阪大学蛋白質研究所セミナー 「がん研究の新機軸」
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] 時系列・一細胞解析による抗がん剤耐性獲得過程の理解2019

    • Author(s)
      間木 重行
    • Organizer
      新学術領域研究「数理シグナル」 第3回 若手ワークショップ
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] Model-based identification of ErbB network principles among cell types2019

    • Author(s)
      Imoto H, Ebata K, Zhang S, Magi S, Okada M
    • Organizer
      The 20th International Conference of Systems Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] A comprehensive model of heterogeneous cell cycle responses2019

    • Author(s)
      Imoto H, Ebata K, Magi S, Zhang S, Okada M
    • Organizer
      The 57th Annual Meeting of the Biophysical Society of Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] Crosstalk between the estrogen receptor and ErbB signaling pathways in breast cancer cells2019

    • Author(s)
      Zhang S, Magi S, Okada M
    • Organizer
      the 78th Annual Meeting of the Japanese Cancer Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] 時系列・一細胞解析から見える抗がん剤耐性獲得過程2019

    • Author(s)
      間木 重行
    • Organizer
      大阪大学蛋白質研究所セミナー 「がん研究の新機軸」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] Model-based identification of ErbB network principles among cell types2019

    • Author(s)
      Imoto H, Ebata K, Zhang S, Magi S, Okada M
    • Organizer
      The 20th International Conference of Systems Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] A hybrid mathematical model for design and optimization of tamoxifen treatment in MCF-7 breast cancer cells2019

    • Author(s)
      Dominguez-Huttinger E, Magi S, AntoniA A, Ortiz O., Ramirez A.R., Okada M
    • Organizer
      The 20th International Conference on Systems Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] Crosstalk between the estrogen receptor and ErbB signaling pathways in breast cancer cells2019

    • Author(s)
      Zhang S, Magi S, Okada M
    • Organizer
      the 78th Annual Meeting of the Japanese Cancer Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] オートファジーが関与する抗がん剤耐性獲得過程の数理モデル解析2019

    • Author(s)
      間木 重行
    • Organizer
      令和元年 「数理シグナル」 領域推進会議
    • Data Source
      KAKENHI-PUBLICLY-19H04963
  • [Presentation] 時系列・一細胞解析による抗がん剤耐性獲得過程の理解2019

    • Author(s)
      間木重行, 奇 世媛, 鵜飼正雄, 鈴木 穣, 岡田眞里子
    • Organizer
      日本バイオインフォマティクス学会 2019年年会・ 第8回生命医薬情報学連合大会
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] 乳がん細胞におけるタモキシフェン耐性獲得過程の時系列解析2018

    • Author(s)
      間木重行
    • Organizer
      新学術領域「代謝統合オミクス」第一回若手合宿
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] 乳がん細胞におけるタモキシフェン耐性獲得過程の時系列解析2018

    • Author(s)
      間木重行
    • Organizer
      大阪大学大学院医学系研究科 第11回 若手研究フォーラム
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] Time-series analysis on the process of acquiring tamoxifen resistance in breast cancer cells2018

    • Author(s)
      Shigeyuki Magi, Yutaka Suzuki, Mariko Okada
    • Organizer
      日本癌学会 2018
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] Time-series analysis on the process of acquiring tamoxifen resistance in breast cancer cells2018

    • Author(s)
      Shigeyuki Magi, Sewon Ki, Masao Ukai, Yutaka Suzuki, Mariko Okada
    • Organizer
      日本分子生物学会 2018
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] Understanding negative feedback mechanism of ErbB signaling using mathematical modeling of cell population dynamics2018

    • Author(s)
      Shigeyuki Magi
    • Organizer
      Frontiers of Multiscale Structural Biology: Order-disorder transitions and dynamic membrane interactions
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] 乳がん細胞におけるタモキシフェン耐性獲得過程の時系列解析2018

    • Author(s)
      間木重行
    • Organizer
      第一回がんと代謝研究会・若手の会
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] Time‐Series Analysis on the Process of Acquiring Resistance for Estrogen Receptor Antagonist in Breast Cancer Cells2018

    • Author(s)
      Shigeyuki Magi
    • Organizer
      3rd Symposium on Complex Biodynamics + Networks
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] 乳がんの内分泌療法抵抗正獲得過程の時系列解析2017

    • Author(s)
      間木重行 奇世媛 鵜飼正雄 鈴木穣 岡田眞里子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-17K18359
  • [Presentation] シグナルの定量解析と数理モデルによる分子制御機構の同定2017

    • Author(s)
      間木重行
    • Organizer
      生化学会近畿部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K18359
  • 1.  内藤 篤彦 (10588891)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  岡田 眞里子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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