KOBAYASHI Takashi 小林隆

Researcher Number	90709669
Other IDs	https://orcid.org/0000-0002-9202-7643
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2022: 神戸大学, 医学研究科, 特命助教 2020 – 2021: 神戸大学, 医学研究科, 助教 2018 – 2019: 神戸大学, 医学研究科, 特命助教 2017: 神戸大学, 医学研究科, 医学研究員 2016: 神戸大学, 医学研究科, 特命助教 2014 – 2015: 神戸大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 質量分析 / 膵がん / バイオマーカー / メタボロミクス / IPMN / 血液 / 代謝 / 代謝物 / 膵疾患 / 多重ロジスティック … More / 高リスクIPMN / 代謝物バイオマーカー / MS / 膵液 / biomarker / screening / metabolomics / pancreatic cancer / LC/MS / GC/MS / スクリーニング … More Except Principal Investigator 膵管擦過細胞診 / EUS-FNA / ゼノグラフト / PanIN / 早期膵癌 / 膵癌 / オルガノイド Less

早期膵癌オルガノイドの樹立による腫瘍進展機構の解明
- Principal Investigator
  
  塩見英之
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
Metabolic biomarker of pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kobe University
Pancreatic disease screening and grade evaluation system using metabolomics with blood and pancreatic juicePrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takashi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
Serum Metabolomics as a Screening Method for Pancreatic CancerPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University

All 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] 胆と膵2020
- Author(s)
  小林　隆
- Total Pages
  5
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-18K07266
[Book] 臨床消化器内科2016
- Author(s)
  小林隆, 久津見弘, 八木洋輔, 酒井新, 吉中勇人, 西海信, 吉田優, 東健
- Total Pages
  6
- Publisher
  日本メディカル
- Data Source
  KAKENHI-PROJECT-16K19342
[Book] 臨床検査　メタボロミクスによる癌診断の新たな展開2015
- Author(s)
  酒井　新、西海　信、小林　隆、東　健、吉田　優
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-26860504
[Journal Article] Possibility of detecting intraductal papillary mucinous neoplasms using metabolite biomarkers for pancreatic cancer2020
- Author(s)
  Nakano Ryota、Nishiumi Shin、Kobayashi Takashi、Ikegawa Takuya、Kodama Yuzo、Yoshida Masaru
- Journal Title
  
  Biomarkers in Medicine
  
  Volume: 14 Issue: 11 Pages: 1009-1020
- DOI
  10.2217/bmm-2019-0587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07266
[Journal Article] Clinical outcome of conservatively managed pancreatic intraductal papillary mucinous neoplasms with mural nodules and main duct dilation2020
- Author(s)
  Sakai Arata、Masuda Atsuhiro、Eguchi Takaaki、Anami Takahiro、Nishi Katsuhisa、Furumatsu Keisuke、Okabe Yoshihiro、Kakuyama Saori、Sato Yu、Nishioka Chiharu、Sanuki Tsuyoshi、Yagi Yosuke、Kobayashi Takashi、Shiomi Hideyuki、Kodama Yuzo
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 3 Pages: 285-292
- DOI
  10.1007/s00535-020-01739-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08444, KAKENHI-PROJECT-18K07266
[Journal Article] Evaluation of efficacy of pancreatic juice cytology for risk classification according to international consensus guidelines in patients with intraductal papillary mucinous neoplasm; a retrospective study2019
- Author(s)
  Yamakawa Kohei、Masuda Atsuhiro、Nakagawa Takashi、Kobayashi Takashi、Tsujimae Masahiro、Ashina Shigeto、Yamada Yasutaka、Tanaka Takeshi、Tanaka Shunta、Nakano Ryota、Sato Yu、Ikegawa Takuya、Kurosawa Manabu、Fujigaki Seiji、Kutsumi Hiromu、Itoh Tomoo、Fukumoto Takumi、Kodama Yuzo
- Journal Title
  
  Pancreatology
  
  Volume: 19 Issue: 3 Pages: 424-428
- DOI
  10.1016/j.pan.2019.02.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07266, KAKENHI-PROJECT-19K08444
[Journal Article] Trends in biomarker discoveries for the early detection and risk stratification of pancreatic cancer using omics studies2019
- Author(s)
  Kobayashi Takashi、Honda Kazufumi
- Journal Title
  
  Expert Review of Molecular Diagnostics
  
  Volume: 19 Issue: 8 Pages: 651-654
- DOI
  10.1080/14737159.2019.1643718
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07266, KAKENHI-PROJECT-19H03856
[Journal Article] Significance of pancreatic calcification on preoperative computed tomography of intraductal papillary mucinous neoplasms2019
- Author(s)
  Tsujimae Masahiro、Masuda Atsuhiro、Shiomi Hideyuki、Kobayashi Takashi、Sakai Arata、Kutsumi Hiromu、Zen Yoh、Itoh Tomoo、Fukumoto Takumi、Kodama Yuzo
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 34 Issue: 9 Pages: 1648-1655
- DOI
  10.1111/jgh.14732
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07266, KAKENHI-PROJECT-19K08444
[Journal Article] Differences in metabolite profiles caused by pre-analytical blood processing procedures2018
- Author(s)
  Shin Nishiumi, Makoto Suzuki, Takashi Kobayashi, Masaru Yoshida
- Journal Title
  
  Journal of Bioscience and Bioengnieering
  
  Volume: 125(5) Issue: 5 Pages: 613-618
- DOI
  10.1016/j.jbiosc.2017.11.011
- NAID
  120006517720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07266
[Journal Article] Metabolome analysis for pancreatic cancer risk in nested case-control study: Japan Public Health Center-based prospective Study2018
- Author(s)
  Nakagawa T, Kobayashi T, Nishiumi S, Hidaka A, Yamaji T, Sawada N, Hirata Y, Yamanaka K, Azuma T, Goto A, Shimazu T, Inoue M, Iwasaki M, Yoshida M, Tsugane S
- Journal Title
  
  Cancer Sci.
  
  Volume: 25 Issue: 5 Pages: 1672-1681
- DOI
  10.1111/cas.13573
- NAID
  120006482610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19342
[Journal Article] Pancreatic cancer screening using a multiplatform human serum metabolomics system2016
- Author(s)
  Sakai A., Suzuki M., Kobayashi T., Nishiumi S., Yamanaka K., Hirata Y., Nakagawa T., Azuma T., Yoshida M
- Journal Title
  
  Biomarkers in Medicine
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860504
[Journal Article] Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics.2016
- Author(s)
  Hirata Y., Ioka T., et al.
- Journal Title
  
  Clin. Chim. Acta.
  
  Volume: Feb. 16 Pages: 98-104
- DOI
  10.1016/j.cca.2017.02.011
- NAID
  120006375910
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04913, KAKENHI-PROJECT-16H05227, KAKENHI-PROJECT-16K19342, KAKENHI-PROJECT-16K11712, KAKENHI-PROJECT-17K10712, KAKENHI-PROJECT-16H05547, KAKENHI-PROJECT-16K15833
[Journal Article] Metabolomics evaluation of serum markers for cachexia and their intra-day variation in patients with advanced pancreatic cancer2014
- Author(s)
  Fujiwara Y, Kobayashi T, Chayahara N, Imamura Y, Toyoda M, Kiyota N, Mukohara T, Nishiumi S, Azuma T, Yoshida M, Minami H
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 11 Pages: e113259-e113259
- DOI
  10.1371/journal.pone.0113259
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860504
[Journal Article] Metabolomics for Biomarker Discovery in Gastroenterological Cancer2014
- Author(s)
  Nishiumi S., Suzuki M., Kobayashi T., Matsubara A., Azuma T., Yoshida M.
- Journal Title
  
  Metabolites
  
  Volume: 4 Issue: 3 Pages: 547-571
- DOI
  10.3390/metabo4030547
- NAID
  120005619642
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293131, KAKENHI-PROJECT-25560237, KAKENHI-PROJECT-26860504
[Presentation] 膵癌のバイオマーカー候補代謝物による、IPMN同定の可能性2020
- Author(s)
  中野遼太　小林隆　吉田優
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07266
[Presentation] 血液メタボロミクスによる膵がんスクリーニング法の開発2018
- Author(s)
  小林　隆、平田　祐一、吉田　優
- Organizer
  日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-16K19342
[Presentation] 血液メタボロミクスによる膵がんスクリーニング法の開発2018
- Author(s)
  小林　隆、平田　祐一、吉田　優
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07266
[Presentation] Validation of serum/plasma metabolomic biomarkers against pancreatic cancer by quantitative targeted GC/MS/MS2017
- Author(s)
  Takashi Kobayashi, Yuichi Hirata, Masaru Yoshida, Shin Nishiumi, Kazufumi Honda
- Organizer
  UEGW2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19342
[Presentation] 微量の血液からのメタボロミクスによる疾患診断2015
- Author(s)
  小林隆, 西海信, 吉田優
- Organizer
  メディカルジャパン2015大阪
- Place of Presentation
  インテックス大阪（大阪府・大阪市）
- Year and Date
  2015-02-05
- Data Source
  KAKENHI-PROJECT-26860504
[Presentation] 血清メタボロミクスによる早期大腸がんスクリーニングシステムの開発2015
- Author(s)
  小林　隆、吉田　優、東　健
- Organizer
  第57回日本消化器病学会大会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-26860504
[Presentation] 血清メタボロミクスによる膵癌スクリーニング法の検討2014
- Author(s)
  小林隆, 塩見英之, 久津見弘, 山中広大, 平田祐一, 八木洋輔, 那賀川峻, 野村雄大, 江崎健, 酒井新, 竹中完, 増田充弘, 有坂好史
- Organizer
  第45回日本膵臓学会大会
- Place of Presentation
  北九州国際会議場(福岡県・北九州市）
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-26860504
[Presentation] 血清メタボロミクスによる新規バイオマーカーの開発2014
- Author(s)
  小林隆
- Organizer
  第52回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-08-28
- Invited
- Data Source
  KAKENHI-PROJECT-26860504
[Presentation] 血清メタボローム解析による膵癌スクリーニング法の有用性2014
- Author(s)
  小林隆, 吉田優, 東健
- Organizer
  第56回日本消化器病学会大会
- Place of Presentation
  神戸国際展示場（兵庫県・神戸市）
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-26860504

1. 西海信 (20514706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 塩見英之 (40595485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 増田充弘 (60512530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 児玉裕三 (80378687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 井岡達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 吉田優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOBAYASHI Takashi 小林 隆

Research Projects

Research Products

Co-Researchers

早期膵癌オルガノイドの樹立による腫瘍進展機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Metabolic biomarker of pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pancreatic disease screening and grade evaluation system using metabolomics with blood and pancreatic juicePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Serum Metabolomics as a Screening Method for Pancreatic CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 胆と膵2020

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床消化器内科2016

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床検査 メタボロミクスによる癌診断の新たな展開2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Possibility of detecting intraductal papillary mucinous neoplasms using metabolite biomarkers for pancreatic cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical outcome of conservatively managed pancreatic intraductal papillary mucinous neoplasms with mural nodules and main duct dilation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of efficacy of pancreatic juice cytology for risk classification according to international consensus guidelines in patients with intraductal papillary mucinous neoplasm; a retrospective study2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trends in biomarker discoveries for the early detection and risk stratification of pancreatic cancer using omics studies2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of pancreatic calcification on preoperative computed tomography of intraductal papillary mucinous neoplasms2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differences in metabolite profiles caused by pre-analytical blood processing procedures2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Metabolome analysis for pancreatic cancer risk in nested case-control study: Japan Public Health Center-based prospective Study2018

Author(s)

Journal Title

DOI

NAID

Data Source

KOBAYASHI Takashi 小林隆

[Book] 臨床検査　メタボロミクスによる癌診断の新たな展開2015