Kawabata Reika 川端麗香

Researcher Number	90721928
Other IDs
Affiliation (Current)	2023: 群馬大学, 未来先端研究機構, 講師
Affiliation (based on the past Project Information) *help	2018 – 2022: 群馬大学, 未来先端研究機構, 講師 2017: 群馬大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Genome biology / Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 53020:Cardiology-related / Basic Section 55040:Respiratory surgery-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 55020:Digestive surgery-related / Basic Section 58040:Forensics medicine-related / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 新規治療標的 / 肺がん / トリプルネガティブ乳がん / 予後予測マーカー / 治療標的 / RNA-seq / 免疫組織染色 / バイオマーカー / 小細胞肺がん / 肺扁平上皮がん … More / 化学療法耐性機構 / 癌 / ゲノム / 遺伝子 / 膵がん / O-GlcNAc修飾 / KRAS / O-GlcNAc / 抗がん剤感受性 / 多階層オミクス解析 … More Except Principal Investigator エピゲノム / 遺伝性不整脈 / 遺伝性QT延長症候群 / Caチャネル / CACNA1C / 機能異常 / SCN5A / 遺伝性不整脈症候群 / 次世代シークエンス / 遺伝子変異 / イオンチャネル / 構造-機能連関 / FOXM1 / Chk1 / 小細胞肺癌 / ATR / MDR-1 / 抗がん剤耐性 / エピジェネティクス / ゲノム編集 / エピゲノム編集 / 子宮体癌 / 肥満 / エピトランスクリプトーム / 視床下部 / 形態病理 / 分化 / 肝がん / 突然死 / 脂肪肝 / 脂肪酸 / 代謝異常 / エクソーム / 生理活性脂質 / S1P / 炎症 / 近接ラベル化法 / 慢性炎症 / 受容体 / メトロノーム化学療法 Less

肝がんの分化規定遺伝子の同定と革新的治療法の開発
- Principal Investigator
  
  播本憲史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Gunma University
Exome and lipidome analysis to elucidate the mechanisms of sudden death with hepatic steatosis
- Principal Investigator
  
  高橋遥一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Gunma University
The role of epigenome and epitranscriptome in the development of obesity
- Principal Investigator
  
  河野大輔
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gunma University
Regulation of chronic inflammation of blood vessels by a bioactive lipid mediator
- Principal Investigator
  
  大日方英
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Gunma University
膵がん治療におけるO-GlcNAc分解酵素OGAの重要性とその分子機構の解明Principal Investigator
- Principal Investigator
  
  川端麗香
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Gunma University
EphA4活性化により生じる高分化型口腔癌メトロノーム化学療法耐性機構の解明
- Principal Investigator
  
  喜名振一郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Gunma University
次世代シークエンス及び電気生理学的手法を駆使した新規遺伝性不整脈の病態解明
- Principal Investigator
  
  中島忠
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Gunma University
Elucidation of anticancer drug resistance mechanism of lung cancer through FOXM1
- Principal Investigator
  
  大瀧容一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Gunma University
Histone methyltransferase KMT2 mutation-induced epigenomic abnormalities and endometrial cancer development and progression
- Principal Investigator
  
  畑田出穂
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Gunma University
Identification of novel biomarkers and therapeutic targets for refractory malignant solid tumors by comprehensive omics analysesPrincipal Investigator
- Principal Investigator
  
  Kawabata Reika
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genome biology
- Research Institution
  Gunma University

All 2022 2021 2020 2019 2017

All Journal Article Presentation

[Journal Article] Robust Validation and Comprehensive Analysis of a Novel Signature Derived from Crucial Metabolic Pathways of Pancreatic Ductal Adenocarcinoma2022
- Author(s)
  Gu Wenchao、Mo Shaocong、Wang Yulin、Kawabata-Iwakawa Reika、Zhang Wei、Yang Zongcheng、Sun Chenyu、Tsushima Yoshito、Xu Huaxiang、Nakajima Takahito
- Journal Title
  
  Cancers
  
  Volume: 14 Pages: 1825-1825
- DOI
  10.3390/cancers14071825
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08680
[Journal Article] Reduced current density, partially rescued by mexiletine, and depolarizing shift in activation of SCN5A W374G channels as a cause of severe form of Brugada syndrome2021
- Author(s)
  Nakajima Tadashi、Dharmawan Tommy、Kawabata‐Iwakawa Reika、Tamura Shuntaro、Hasegawa Hiroshi、Kobari Takashi、Ota Masaki、Tange Shoichi、Nishiyama Masahiko、Kaneko Yoshiaki、Kurabayashi Masahiko
- Journal Title
  
  Annals of Noninvasive Electrocardiology
  
  Volume: 26
- DOI
  10.1111/anec.12828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08487
[Journal Article] A molecular signature of well-differentiated oral squamous cell carcinoma reveals a resistance mechanism to metronomic chemotherapy and novel therapeutic candidates2021
- Author(s)
  Kina S, Kawabata-Iwakawa R, Miyamoto S, Arasaki A, Sunakawa H, Kinjo T.
- Journal Title
  
  J Drug Target .
  
  Volume: 29 Pages: 1118-1127
- DOI
  10.1080/1061186x.2021.1929256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08655, KAKENHI-PROJECT-21K10084
[Journal Article] Multiple arrhythmic and cardiomyopathic phenotypes associated with an SCN5A A735E mutation2021
- Author(s)
  Sasaki Takashi、Ikeda Kentaro、Nakajima Tadashi、Kawabata-Iwakawa Reika、Iizuka Takashi、Dharmawan Tommy、Tamura Shuntaro、Niwamae Nogiku、Tange Shoichi、Nishiyama Masahiko、Kaneko Yoshiaki、Kurabayashi Masahiko
- Journal Title
  
  Journal of Electrocardiology
  
  Volume: 65 Pages: 122-127
- DOI
  10.1016/j.jelectrocard.2021.01.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08487
[Journal Article] Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer2021
- Author(s)
  Coll-SanMartin Laia、Davalos Veronica、Pi?eyro David、Rossell?-Tortella Margalida、Bueno-Costa Alberto、Setien Fernando、Villanueva Alberto、Granada Isabel、Ruiz-Xiviller Neus、Kotter Annika、Helm Mark、Yokota Jun、Kawabata-Iwakawa Reika、Kohno Takashi、Esteller Manel
- Journal Title
  
  Cancers
  
  Volume: 13 Pages: 1869-1869
- DOI
  10.3390/cancers13081869
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15038
[Journal Article] Novel Cardiocerebral Channelopathy Associated with a <i>KCND3</i> V392I Mutation2020
- Author(s)
  Nakajima Tadashi、Kawabata-Iwakawa Reika、Kaneko Yoshiaki、Hamano Shin-ichiro、Sano Rie、Tamura Shuntaro、Hasegawa Hiroshi、Kobari Takashi、Kominato Yoshihiko、Nishiyama Masahiko、Kurabayashi Masahiko
- Journal Title
  
  International Heart Journal
  
  Volume: 61 Issue: 5 Pages: 1049-1055
- DOI
  10.1536/ihj.20-203
- NAID
  130007911359
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08487, KAKENHI-PROJECT-20K21697, KAKENHI-PROJECT-19H03916
[Journal Article] Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine2020
- Author(s)
  Bilguun Erkhem-Ochir、Kaira Kyoichi、Kawabata-Iwakawa Reika、Rokudai Susumu、Shimizu Kimihiro、Yokobori Takehiko、Oyama Tetsunari、Shirabe Ken、Nishiyama Masahiko
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Pages: 935-935
- DOI
  10.1186/s12885-020-07448-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15038
[Journal Article] Biophysical defects of an SCN5A V1667I mutation associated with epinephrine‐induced marked QT prolongation2020
- Author(s)
  Nakajima Tadashi、Dharmawan Tommy、Kawabata‐Iwakawa Reika、Tamura Shuntaro、Hasegawa Hiroshi、Kobari Takashi、Kaneko Yoshiaki、Nishiyama Masahiko、Kurabayashi Masahiko
- Journal Title
  
  Journal of Cardiovascular Electrophysiology
  
  Volume: 31 Pages: 2107-2115
- DOI
  10.1111/jce.14575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08487
[Journal Article] Carboxypeptidase A4 accumulation is associated with an aggressive phenotype and poor prognosis in triple-negative breast cancer.2019
- Author(s)
  Handa Tadashi、Katayama Ayaka、Yokobori Takehiko、Yamane Arito、Fujii Takaaki、Obayashi Sayaka、Kurozumi Sasagu、Kawabata-Iwakawa Reika、Gombodorj Navchaa、Nishiyama Masahiko、Asao Takayuki、Shirabe Ken、Kuwano Hiroyuki、Oyama Tetsunari
- Journal Title
  
  Int J Oncol.
  
  Volume: Mar;54(3) Pages: 833-844
- DOI
  10.3892/ijo.2019.4675
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07665, KAKENHI-PROJECT-17K15038, KAKENHI-PROJECT-17K19893, KAKENHI-PROJECT-19K07456
[Journal Article] Stathmin-1 Is a Useful Diagnostic Marker for High-Grade Lung Neuroendocrine Tumors2019
- Author(s)
  Shimizu Kimihiro、Goto Yusuke、Kawabata-Iwakawa Reika、Ohtaki Yoichi、Nakazawa Seshiru、Yokobori Takehiko、Obayashi Kai、Kawatani Natsuko、Yajima Toshiki、Kaira Kyoichi、Mogi Akira、Hirato Junko、Nishiyama Masahiko、Shirabe Ken
- Journal Title
  
  The Annals of Thoracic Surgery
  
  Volume: 108 Pages: 235-243
- DOI
  10.1016/j.athoracsur.2019.02.040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15038
[Journal Article] Next-Generation Sequencing and Bioinformatics2017
- Author(s)
  Kawabata-Iwakawa Reika、Bono Hidemasa、Nishiyama Masahiko
- Journal Title
  
  Molecular Targeted Therapy of Lung Cancer
  
  Volume: - Pages: 97-115
- DOI
  10.1007/978-981-10-2002-5_6
- Data Source
  KAKENHI-PROJECT-17K15038
[Journal Article] High STMN1 Expression is Associated with Cancer Progression and Chemo-Resistance in Lung Squamous Cell Carcinoma2017
- Author(s)
  Bao Pinjie、Yokobori Takehiko、Altan Bolag、Iijima Misaki、Azuma Youko、Onozato Ryoichi、Yajima Toshiki、Watanabe Akira、Mogi Akira、Shimizu Kimihiro、Nagashima Toshiteru、Ohtaki Yoichi、Obayashi Kai、Nakazawa Seshiru、Bai Tuya、Kawabata-Iwakawa Reika、Asao Takayuki、Kaira Kyoichi、Nishiyama Masahiko、Kuwano Hiroyuki
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 24 Pages: 4017-4024
- DOI
  10.1245/s10434-017-6083-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15038, KAKENHI-PROJECT-15K10085
[Journal Article] STXBP4 Drives Tumor Growth and Is Associated with Poor Prognosis through PDGF Receptor Signaling in Lung Squamous Cell Carcinoma2017
- Author(s)
  Otaka Yukihiro、Rokudai Susumu、Kaira Kyoichi、Fujieda Michiru、Horikoshi Ikuko、Iwakawa-Kawabata Reika、Yoshiyama Shinji、Yokobori Takehiko、Ohtaki Yoichi、Shimizu Kimihiro、Oyama Tetsunari、Tamura Jun'ichi、Prives Carol、Nishiyama Masahiko
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 23 Pages: 3442-3452
- DOI
  10.1158/1078-0432.ccr-16-1815
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15038
[Journal Article] Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients.2017
- Author(s)
  Handa Tadashi、Katayama Ayaka、Yokobori Takehiko、Yamane Arito、Horiguchi Jun、Kawabata-Iwakawa Reika、Rokudai Susumu、Bao Pinjie、Gombodorj Navchaa、Altan Bolag、Kaira Kyoichi、Asao Takayuki、Kuwano Hiroyuki、Nishiyama Masahiko、Oyama Tetsunari
- Journal Title
  
  J Surg Oncol.
  
  Volume: 116 Pages: 706-715
- DOI
  10.1002/jso.24705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15038, KAKENHI-PROJECT-15K08339
[Journal Article] Significantly mutated genes and regulatory pathways in SCLC?a meta-analysis2017
- Author(s)
  Sundaresan Varsha、Lin Victor T.、Liang Faming、Kaye Frederic J.、Kawabata-Iwakawa Reika、Shiraishi Kouya、Kohno Takashi、Yokota Jun、Zhou Lei
- Journal Title
  
  Cancer Genetics
  
  Volume: 216-217 Pages: 20-28
- DOI
  10.1016/j.cancergen.2017.05.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15038
[Journal Article] Myeloid sarcoma arising in malignant phyllodes tumour: clonal relationships revealed by comparative genome-wide analyses2017
- Author(s)
  Arai Hideo、Nobusawa Sumihito、Kawabata-Iwakawa Reika、Rokudai Susumu、Higuchi Toru、Yamazaki Tatsuya、Horiguchi Jun、Sano Takaaki、Kojima Masaru、Nishiyama Masahiko、Yokoo Hideaki、Hirato Junko、Oyama Tetsunari
- Journal Title
  
  British Journal of Haematology
  
  Volume: 181 Pages: 255-259
- DOI
  10.1111/bjh.14539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15038
[Presentation] 失神を伴う痙攣発作の原因が異なる可能性がある若年姉妹例2022
- Author(s)
  長谷川寛、中島忠、河内英行、川端麗香、田村峻太郎、小針尭司、西山正彦、倉林正彦、金古善明、石井秀樹
- Organizer
  第2回日本不整脈心電学会関東甲信越支部地方会
- Data Source
  KAKENHI-PROJECT-20K08487
[Presentation] Biophysical Defects of an SCN5A V1667I Mutation Associated with Epinephrine-Induced Marked QT Prolongation2022
- Author(s)
  Tadashi Nakajima, Tommy Dharmawan, Reika Kawabata-Iwakawa, Shuntaro Tamura, Hiroshi Hasegawa, Takashi Kobari, Yoshiaki Kaneko, Masahiko Nishiyama, Masahiko Kurabayashi
- Organizer
  第67回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08487
[Presentation] Utility of glycosylation regulation for pancreatic cancer treatment.2021
- Author(s)
  Reika Kawabata, Hideru Obinata, Navchaa Gombodorj, Takehiko Yokobori
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-21K08680

1. 横堀武彦 (60420098)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 畑田出穂 (50212147)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 大日方英 (50332557)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 西山正彦 (20198526)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. 小林良祐 (30802855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 調憲 (70264025)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 中島忠 (40510574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 倉林正彦 (00215047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 金古善明 (60302478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. 大瀧容一 (00625402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 矢島俊樹 (20346852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 堀居拓郎 (00361387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 森田純代 (40589264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 河野大輔 (10382904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 播本憲史 (00419582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 三森功士 (50322748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 伊古田勇人 (90420116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 高橋遥一郎 (50640538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大嶋紀安 (30360514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 平野瞳子 (20643810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 窪理英子 (40747127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 佐野利恵 (70455955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 早川輝 (90758575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 南嶋洋司 (20593966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 喜名振一郎 (40422422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 金城貴夫 (30284962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 喜名美香 (80578914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. 宮本昇 (80749565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. FUJII Takaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. YAMANE Arito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 小湊慶彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 桑野博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
33. 小山徹也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kawabata Reika 川端 麗香

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膵がん治療におけるO-GlcNAc分解酵素OGAの重要性とその分子機構の解明Principal Investigator

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Identification of novel biomarkers and therapeutic targets for refractory malignant solid tumors by comprehensive omics analysesPrincipal Investigator

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[Journal Article] Robust Validation and Comprehensive Analysis of a Novel Signature Derived from Crucial Metabolic Pathways of Pancreatic Ductal Adenocarcinoma2022

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[Journal Article] Reduced current density, partially rescued by mexiletine, and depolarizing shift in activation of SCN5A W374G channels as a cause of severe form of Brugada syndrome2021

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[Journal Article] A molecular signature of well-differentiated oral squamous cell carcinoma reveals a resistance mechanism to metronomic chemotherapy and novel therapeutic candidates2021

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[Journal Article] Multiple arrhythmic and cardiomyopathic phenotypes associated with an SCN5A A735E mutation2021

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DOI

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[Journal Article] Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer2021

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Kawabata Reika 川端麗香