Saito Akiko 齋藤暁子

Researcher Number	90722835
Other IDs
Affiliation (Current)	2025: 東京歯科大学, 歯学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京歯科大学, 歯学部, 助教 2014 – 2015: 東京歯科大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 57010:Oral biological science-related / Functional basic dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Orthodontics/Pediatric dentistry / Pathobiological dentistry/Dental radiology
Keywords	Principal Investigator 疾患iPS細胞 / 骨芽細胞分化 / 核膜タンパク質 / 疾患特異的iPS細胞 / RUNX2 / 鎖骨頭蓋骨異形成症 / iPS細胞 / ラミノパチー / Lefty / 癌 … More Except Principal Investigator … More iPS細胞 / Gorlin症候群 / 線維性骨異形成症 / GNAS / Hedgehog経路 / 骨芽細胞 / ヘッジホッグ / 多重変異 / 遺伝子変異 / 疾患iPS細胞 / 診断パネル / 遺伝子パネル / ゴーリン症候群 / シングルセル解析 / McCuneAlbright 症候群 / FGFG2 / 骨芽細胞分化誘導 / 遺伝性稀少疾患 / 線維化 / 骨異形成症 / Hedghog / 骨芽細胞分化 / 遺伝子編集 / 悪性腫瘍 / Gタンパク質 / McCune Albright Syndrome / GANS / ヘッジホッグ経路 / マキューンオルブライト症候群 / ｃAMP / 石灰化 / iPS / Hedgehog / cAMP / 骨粗しょう症治療薬 / 骨代謝 / McCuneAlbright症候群 / GPCR / 消化管腫瘍 / McCune Albright 症候群 / 骨 / Golrin症候群 / 上皮細胞分化 / 疾患特異的iPSC / ドライバー遺伝子 / 基底細胞癌 / 歯原性角化嚢胞 / ゲノム編集 / Gain of function / 未分化間葉系幹細胞 / 疾患特異的iPS細胞 / FGFR2 / Apert症候群 / 病理学 / 歯学 / GNAS1 / McCune-Albright症候群 / McCune-Albright 症候群 Less

骨芽細胞核におけるRunx2-Lamin Aの遺伝子発現制御機構の解明Principal Investigator
- Principal Investigator
  
  齋藤暁子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Tokyo Dental College
Development of a new treatment for fibrodysplasia using active genomics and high-throughput analysis
- Principal Investigator
  
  AZUMA TOSHIFUMI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Dental College
Multi-layered mutations in patient with Gorlin syndrome may affect the phenotype
- Principal Investigator
  
  小野寺晶子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Dental College
Elucidation of the regulatory mechanism of osteoblast differentiation based on a new concept and development of therapeutic agents for cleidocranial dysplasia.Principal Investigator
- Principal Investigator
  
  Saito Akiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Tokyo Dental College
Odontogenic keratocyst model using iPSCs derived from patient with Golin syndrome
- Principal Investigator
  
  Onodera Shoko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Dental College
Elucidation of osteoblast mineralization mechanism using McCunealbright syndrome iPS cells
- Principal Investigator
  
  AZUMA TOSHIFUMI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Dental College
Establishment and application of disease-specific iPS cells for Apert syndrome
- Principal Investigator
  
  Ishii Takenobu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tokyo Dental College
Establishment of iPS cells from McCune-Albright syndrome and it application
- Principal Investigator
  
  Yamaguchi Akira
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Dental College
Elucidation of the pathophysiology of cleidocranial dysplasia using disease-specific iPS cellsPrincipal Investigator
- Principal Investigator
  
  Saito Akiko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College
Elucidation of the expression regulatory mechanism of tumor suppressor gene Lefty reprogrammed leukoplakia cellsPrincipal Investigator
- Principal Investigator
  
  Saito Akiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] FGF-2 promotes proliferation and consequently induces osteoblast differentiation in mesenchymal stem cells.2023
- Author(s)
  Ogura H, Nakamura T, Ishii T, Saito A, Onodera S, Yamaguchi A, Nishii Y, Azuma T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 684 Pages: 684-684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03146
[Journal Article] Current Status of Next-Generation Sequencing in Bone Genetic Diseases2023
- Author(s)
  Aida Natsuko、Saito Akiko、Azuma Toshifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 18 Pages: 13802-13802
- DOI
  10.3390/ijms241813802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K09342, KAKENHI-PROJECT-21H03146
[Journal Article] Induced pluripotent stem cells from homozygous Runx2-deficient mice show poor response to vitamin D during osteoblastic differentiation2022
- Author(s)
  Aoki Hideto、Suzuki Eiichi、Nakamura Takashi、Onodera Shoko、Saito Akiko、Ohtaka Manami、Nakanishi Mahito、Nishimura Ken、Saito Atsushi、Azuma Toshifumi
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 000 Issue: 3 Pages: 000-000
- DOI
  10.1007/s00795-022-00317-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03146, KAKENHI-PROJECT-21K17027, KAKENHI-PROJECT-21K10103
[Journal Article] Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages2022
- Author(s)
  Hojo Hironori, Saito Taku, He Xinjun, Guo Qiuyu, Onodera Shoko, Azuma Toshifumi, Koebis Michinori, Nakao Kazuki, Aiba Atsu, Seki Masahide, Suzuki Yutaka, Okada Hiroyuki, Tanaka Sakae, Chung Ung-il, McMahon Andrew P., Ohba Shinsuke
- Journal Title
  
  Cell Reports
  
  Volume: 40 Issue: 10 Pages: 111315-111315
- DOI
  10.1016/j.celrep.2022.111315
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05318, KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-22KK0272, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-23K21494, KAKENHI-PROJECT-21H03146
[Journal Article] Bone regeneration of induced pluripotent stem cells derived from peripheral blood cells in collagen sponge scaffolds2022
- Author(s)
  Kato Hiroshi、Watanabe Katsuhito、Saito Akiko、Onodera Shoko、Azuma Toshifumi、Takano Masayuki
- Journal Title
  
  Journal of Applied Oral Science
  
  Volume: 30
- DOI
  10.1590/1678-7757-2021-0491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19176, KAKENHI-PROJECT-21H03146
[Journal Article] The effect of BMP4, FGF8 and WNT3a on mouse iPS cells differentiating to odontoblast-like cells.2022
- Author(s)
  Takada K, Odashima A, Onodera S, Saito A, Aida N, Furusawa M, Azuma T.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: 55(3) Issue: 3 Pages: 199-209
- DOI
  10.1007/s00795-022-00318-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03146
[Journal Article] Effects of KnockOut Serum Replacement on Differentiation of Mouse-Induced Pluripotent Stem Cells into Odontoblasts2022
- Author(s)
  Furukawa Y, Odashima A, Hoshino T, Onodera S, Saito A, Ichinohe T, Azuma T.
- Journal Title
  
  Bull. Tokyo Dent. Coll.
  
  Volume: 63 Issue: 2 Pages: 75-83
- DOI
  10.2209/tdcpublication.2021-0042
- ISSN
  0040-8891
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03146
[Journal Article] The concurrent stimulation of Wnt and FGF8 signaling induce differentiation of dental mesenchymal cells into odontoblast-like cells2021
- Author(s)
  Kimura Motoyoshi、Saito Akiko、Onodera Shoko、Nakamura Takashi、Suematsu Makoto、Shintani Seikou、Azuma Toshifumi
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 55 Issue: 1 Pages: 8-19
- DOI
  10.1007/s00795-021-00297-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03833, KAKENHI-PROJECT-21H03146, KAKENHI-PROJECT-21K10171, KAKENHI-PROJECT-19K19074
[Journal Article] TSLP is a negative regulator of RANKL-induced osteoclastogenesis.2020
- Author(s)
  Ohno, T., Nakamura, T., Nakae, S., Morita, H., Matsumoto, K., Takeda, K., Okumura, K., and Azuma, T.
- Journal Title
  
  Biochem. Biophsy. Res. Commun.
  
  Volume: 530 Issue: 3 Pages: 508-512
- DOI
  10.1016/j.bbrc.2020.05.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-18H03007
[Journal Article] A novel GNAS-mutated human induced pluripotent stem cell model for understanding GNAS-mutated tumors.2020
- Author(s)
  Watanabe K, Nakamura T, Onodera S, Saito A, Shibahara T, Azuma T.
- Journal Title
  
  Tumour Biol.
  
  Volume: 42(9) Issue: 9 Pages: 1177-1177
- DOI
  10.1177/1010428320962588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03007
[Journal Article] CAGE-seq analysis of osteoblast derived from cleidocranial dysplasia human induced pluripotent stem cells2020
- Author(s)
  Ooki Akio、Onodera Shoko、Saito Akiko、Oguchi Akiko、Murakawa Yasuhiro、Sakamoto Teruo、Sueishi Kenji、Nishii Yasushi、Azuma Toshifumi
- Journal Title
  
  Bone
  
  Volume: 141 Pages: 115582-115582
- DOI
  10.1016/j.bone.2020.115582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21407, KAKENHI-PROJECT-20KK0186, KAKENHI-PROJECT-18H03992, KAKENHI-PROJECT-18H03007
[Journal Article] The effects of parathyroid hormone on osteoblastic differentiation of mouse induced pluripotent stem cells in a 3-D culture model.2020
- Author(s)
  Sato M, Aoki H, Nakamura T, Onodera S, Yamaguchi A, Saito A, Azuma T
- Journal Title
  
  J Period Res
  
  Volume: 55 Issue: 5 Pages: 734-743
- DOI
  10.1111/jre.12762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03894, KAKENHI-PROJECT-18H03007
[Journal Article] Hedgehog Activation Regulates Human Osteoblastogenesis2020
- Author(s)
  Onodera Shoko、Saito Akiko、Hojo Hironori、Nakamura Takashi、Zujur Denise、Watanabe Katsuhito、Morita Nana、Hasegawa Daigo、Masaki Hideki、Nakauchi Hiromitsu、Nomura Takeshi、Shibahara Takahiko、Yamaguchi Akira、Chung Ung-il、Azuma Toshifumi、Ohba Shinsuke
- Journal Title
  
  Stem Cell Reports
  
  Volume: 15 Issue: 1 Pages: 125-139
- DOI
  10.1016/j.stemcr.2020.05.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-20H03894, KAKENHI-PROJECT-18H03007
[Journal Article] Stage-dependent differential gene expression profiles of cranial neural2020
- Author(s)
  Odashima A, Onodera S, Saito A, Ogihara Y, Ichinohe T, Azuma T.
- Journal Title
  
  Med Mol　Morphology
  
  Volume: 53(1) Issue: 1 Pages: 28-41
- DOI
  10.1007/s00795-019-00229-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03007, KAKENHI-PROJECT-19K19247, KAKENHI-PROJECT-19H03833
[Journal Article] Targeted reversion of induced pluripotent stem cells from patients with human cleidocranial dysplasia showed corrected osteoblastic differentiation both in vitro and in vivo.2018
- Author(s)
  Ooki A, Nakamura T, Onodera S, Hayashi K, Hasegawa D, Kato H, Onda T, Watanabe A, Kosaki K, Nishimura K, Ohtaka M, Nakanishi M, Sakamoto T, Yamaguchi A, Sueishi K, Azuma T
- Journal Title
  
  Stem Cell Res Ther
  
  Volume: 9 Issue: 1 Pages: 12-12
- DOI
  10.1186/s13287-017-0754-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K20427, KAKENHI-PROJECT-16K20428, KAKENHI-PROJECT-16K20619, KAKENHI-PROJECT-16K11701
[Journal Article] Multi-layered mutatin in hedgehog-related genes in Gorlin syndrome may affect the phenotype.2017
- Author(s)
  Onodera S, Saito A, Hasegawa D, Watanabe K, Morita N, Nomura T, Shibahara T, Ohba S, Yamaguchi A, Azuma T
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 9 Pages: e0184702-e0184702
- DOI
  10.1371/journal.pone.0184702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-15K15732, KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K20427, KAKENHI-PROJECT-16K20428
[Journal Article] Effect of the combined use of enamel matrix derivative and atelocollagen sponge scaffold on osteoblastic differentiation of mouse induced pluripotent stem cells in vitro2017
- Author(s)
  Hisanaga Y.、Suzuki E.、Aoki H.、Sato M.、Saito A.、Saito A.、Azuma T.
- Journal Title
  
  Journal of periodontal research
  
  Volume: 53 Issue: 2 Pages: 240-249
- DOI
  10.1111/jre.12511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07216, KAKENHI-PROJECT-16K20428
[Journal Article] The HIV co-receptor CCR5 regulates osteoclast function.2017
- Author(s)
  Lee JW, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, Ueha S, Matsushima K, Yamaguchi A, Imai Y, Iimura T.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 2226-2226
- DOI
  10.1038/s41467-017-02368-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K19546, KAKENHI-PROJECT-17K19728, KAKENHI-PROJECT-16K20412, KAKENHI-PROJECT-26293392, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K18578
[Journal Article] Gorlin syndrome-derived induced pluripotent stem cells are hypersensitive to Hedgehog-mediated osteogenic induction.2017
- Author(s)
  Hasegawa D, Shino H, Onodera S, Nakamura T, Saito A, Onda T, Watanabe K, Nishimura K, Ohtaka M, Nakanishi M, Kosaki K, Yamaguchi A, Shibahara T, Azuma T
- Journal Title
  
  PLos One
  
  Volume: 12 Issue: 10 Pages: e0186879-e0186879
- DOI
  10.1371/journal.pone.0186879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K20427, KAKENHI-PROJECT-16K20428
[Journal Article] Promoting effect of 1,25(OH)2 vitamin D3 in osteogenic differentiation from induced pluripotent stem cells to osteocyte like cells2015
- Author(s)
  Kato H, Ochiai-Shino H, Onodera S, Saito A, Takahiko Shibahara, Azuma T
- Journal Title
  
  Open Biology 5(2):140201
  
  Volume: 5(2) Issue: 2 Pages: 140201-140201
- DOI
  10.1098/rsob.140201
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462900, KAKENHI-PROJECT-25861761, KAKENHI-PROJECT-26861560, KAKENHI-PROJECT-26861686
[Journal Article] Akt Activation is Required for TGF-β1-Induced Osteoblast Differentiation of MC3T3-E1 Pre-Osteoblasts.2015
- Author(s)
  Suzuki E, Ochiai-Shino H, Aoki H, Onodera S, Saito A, Saito A, Azuma T
- Journal Title
  
  Plosons
  
  Volume: 9(12) Issue: 12 Pages: e112566-e112566
- DOI
  10.1371/journal.pone.0112566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462900, KAKENHI-PROJECT-25861761, KAKENHI-PROJECT-26861560, KAKENHI-PROJECT-26861686
[Journal Article] A novel strategy for enrichment and isolation of osteoprogenitor cells from induced pluripotent stem cells based on surface marker combination.2014
- Author(s)
  Ochiai-Shino H, Kato H, Sawada T, Onodera S, Saito A, Takato T, Shibahara T, Muramatsu T, Azuma T.
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 6 Pages: e99534-e99534
- DOI
  10.1371/journal.pone.0099534
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462878, KAKENHI-PROJECT-25861761, KAKENHI-PROJECT-26861560, KAKENHI-PROJECT-26861686, KAKENHI-PROJECT-25462900
[Presentation] RUNX2による核膜関連タンパク質の発現調節を介した骨芽細胞分化制御機構2022
- Author(s)
  齋藤暁子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K10063
[Presentation] RUNX2による核膜関連タンパク質の発現調節を介した骨芽細胞分化制御機構2022
- Author(s)
  齋藤暁子
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K10063
[Presentation] Runx2はLINCタンパク質発現調節により骨芽細胞分化を制御する2021
- Author(s)
  東俊文、齋藤暁子、中村貴
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K10063
[Presentation] 『核とミトコンドリア研究』から見えてきた疾患病態の先端分子生物学）Runx2 は　LINCタンパク質発現調節により骨芽細胞分化を制御する。2021
- Author(s)
  東　俊文、齋藤暁子、中村貴
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H03146
[Presentation] 骨細胞のLamin Aは骨リモデリングを制御する。2021
- Author(s)
  奥平　貴人，中村貴 2，齋藤暁子 2，山口朗 1，髙野正行 3，柴原孝彦 3，東俊文 1.2
- Organizer
  第53回日本臨床分子形態学会総会・学術集会,
- Data Source
  KAKENHI-PROJECT-21H03146
[Presentation] 骨芽細胞RUnx2 は核膜タンパク質発現制御を通じて核形態および骨芽細胞分化を制御する。2021
- Author(s)
  東　俊文、齋藤暁子、中村貴
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H03146
[Presentation] 鎖骨頭蓋骨異形成症特異的iPS細胞を用いた骨分化におけるRUNX2と核膜タンパク質による転写制御の検討2019
- Author(s)
  齋藤暁子, 大木章生, 澤田隆, 中村貴, 小野寺晶子, 末石研二, 山口朗, 東俊文
- Organizer
  第307回東京歯科大学学会
- Data Source
  KAKENHI-PROJECT-19K10063
[Presentation] 鎖骨頭蓋骨異形成症由来iPS細胞を用いたRUNX2機能不全と核膜形態異常との関連2018
- Author(s)
  齋藤暁子，大木章生，澤田隆，中村貴，小野寺晶子，長谷川大悟，小崎健次郎，末石研二，東俊文
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K20428
[Presentation] 鎖骨頭蓋骨異形成症患者由来iPS細胞の解析と骨組織分化との関連の検討2017
- Author(s)
  齋藤暁子，大木章生，中村貴，小野寺晶子，篠宏美，長谷川大悟，小崎健次郎，恩田健志，渡邊章，柴原孝彦，末石研二，東俊文
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16K20428
[Presentation] iPS 細胞を用いた顎骨疾患病態解明へのアプローチ2017
- Author(s)
  東俊文、小野寺晶、齋藤暁子、中村貴、大庭伸介、小崎健次郎、山口朗、柴原孝彦
- Organizer
  第５９回歯科基礎医学会総会学術大会アップデートシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K15791
[Presentation] Gorlin 症候群患者由来iPS 細胞を用いた骨芽細胞分化応答2016
- Author(s)
  小野寺晶子、大庭伸介、長谷川大悟、齋藤暁子、篠宏美、渡邊章、大高真奈美、西村健、中西真人、片倉朗、鄭雄一、柴原孝彦、東俊文
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] Gorlin 症候群患者由来細胞を用いたiPS 細胞の樹立と骨芽細胞分化の検討2016
- Author(s)
  篠宏美、長谷川大悟、小野寺晶子、齋藤暁子、大高真奈美、渡邊章、西村健、中西真人、片倉朗、柴原孝彦、東俊文
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] 鎖骨頭蓋異形成症患者由来iPS細胞の樹立と機能解析2016
- Author(s)
  齋藤暁子、大木章生、中村貴、小野寺晶子、篠宏美、長谷川大悟、小崎健次郎、柴原孝彦、末石研二、東俊文
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] Runx2ホモ欠損マウス由来iPS細胞を用いた骨芽細胞分化機構におけるRunx2非依存的経路の解析2016
- Author(s)
  青木栄人，鈴木瑛一，久永幸乃，佐藤正敬，小野寺晶子，篠宏美，齋藤暁子，齋藤淳，東俊文
- Organizer
  第301回東京歯科大学学会・例会
- Place of Presentation
  東京都
- Year and Date
  2016-06-04
- Data Source
  KAKENHI-PROJECT-16K20428
[Presentation] 鎖骨頭蓋骨異形成症患者由来iPS細胞の解析と骨組織分化との関連の検討2016
- Author(s)
  齋藤暁子，大木章生，中村貴，小野寺晶子，篠宏美，長谷川大悟，小崎健次郎，恩田健志，渡邊章，柴原孝彦，末石研二，東俊文
- Organizer
  第34回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K20428
[Presentation] Analyses of osteogenic differentiation in iPS cells derived from cleidocranial dysplasia patients2016
- Author(s)
  Saito A, Oki A, Nakamura T, Onodera S, Shino H, Hasegawa D, Kosaki K, Onda T, Watanabe A, Shibahara T, Sueishi K, Azuma T
- Organizer
  The joint annual scientific meetings of the endocrine society of Australia, the society for reproductive biology and the Australian and new Zealand bone and mineral society
- Place of Presentation
  Gold Coast
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20428
[Presentation] 鎖骨頭蓋異形成症患者由来細胞を用いた疾患特異的iPS細胞の樹立と機能解析2015
- Author(s)
  齋藤暁子、大木章生、中村貴、小野寺晶子、篠宏美、長谷川大悟、小崎健次郎、柴原孝彦、末石研二、東俊文
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] 鎖骨頭蓋異形成症患者由来細胞を用いた疾患特異的iPS細胞の樹立と機能解析2015
- Author(s)
  齋藤暁子、大木章生、中村貴、小野寺晶子、篠宏美、長谷川大悟、小崎健次郎、柴原孝彦、末石研二、東俊文
- Organizer
  第24回硬組織再生生物学会学術大会・総会
- Place of Presentation
  大阪歯科大学
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] 鎖骨頭蓋異形成症患者由来細胞を用いた疾患特異的iPS細胞の樹立と機能解析2015
- Author(s)
  齋藤暁子、中村貴、小野寺晶子、篠宏美、大木章生、長谷川大悟、渡邊章、小崎健次郎、柴原孝彦、末石研二、東俊文
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] Gorlin 症候群患者由来細胞を用いたヒト人工多能性幹細胞（iPS 細胞）の樹立および骨芽細胞分化2015
- Author(s)
  小野寺晶子、長谷川大悟、齋藤暁子、大高真奈美、渡邊章、西村健、片倉朗、柴原孝彦、中西真人、東俊文
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] 基底細胞癌発生機序解明を目指したGorlin症候群患者由来ヒト人工幹細胞(iPS細胞)の樹立
- Author(s)
  長谷川大悟、小野寺晶子、齋藤暁子、大高真奈美、渡邊章、西村健、東俊文、片倉朗、中西真人、柴原孝彦
- Organizer
  第24回日本有病者医療学会総会・学術大会
- Place of Presentation
  旭川市大雪クリスタルホール
- Year and Date
  2015-03-20 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] iPS細胞から誘導した骨芽細胞を用いた創薬評価-活性型ビタミンD3の効果判定-
- Author(s)
  加藤宏、篠宏美、小野寺晶子、齋藤暁子、林宰央、長谷川大悟、柴原孝彦、東俊文
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] Akt is a Key Modulator in TGF-β1-Induced Osteoblast Differentiation
- Author(s)
  Suzuki E, Ochiai-Shino H, Aoki H, Onodera S, Saito A, Azuma T, Saito A
- Organizer
  The 62nd Annual, Meeting of Japanese Association for Dental Research, Dec. 2014, Osaka
- Place of Presentation
  KKR Hotel Osaka
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] 基底細胞母斑症候群（Gorlin症候群）患者由来細胞を用いた疾患特異的ヒト人工多能性幹細胞(iPS細胞)の樹立
- Author(s)
  小野寺晶子、長谷川大悟、齋藤暁子、大高真奈美、渡邊章、西村健、柴原孝彦、片倉朗、中西真人、東俊文
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] 鎖骨頭蓋骨異形成症患者由来細胞を用いた疾患特異的iPS細胞の樹立
- Author(s)
  齋藤暁子、小野寺晶子、大木章生、長谷川大悟、大高真奈美、中西真人、西村健、渡邊章、柴原孝彦、末石研二、東俊文
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26861560
[Presentation] iPS細胞から骨前駆細胞分化誘導および単離の新規方法開発と骨細胞様細胞への分化誘導
- Author(s)
  東俊文、齋藤暁子、小野寺晶子、加藤宏、篠宏美
- Organizer
  第32回日本骨代謝学会学術集会、2014年7月、大阪市
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26861560

1. Onodera Shoko (90637662)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
2. 中村貴 (80431948)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. Yamaguchi Akira (00142430)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. AZUMA TOSHIFUMI (00222612)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. Ishii Takenobu (80433978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 末石研二 (00154427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 柴原孝彦 (50178919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 齋藤淳 (60266559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 間奈津子 (90615379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 長山和亮 (10359763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 村川泰裕 (50765469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 野村武史 (60328268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 溝口利英 (90329475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 片倉朗 (10233743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OHBA Shinsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. UEHA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. Matsushima Kouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 鈴木瑛一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 北條宏徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 加藤宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 篠宏美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 竹田和由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 津村麻記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 村松敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 斎藤一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saito Akiko 齋藤 暁子

Research Projects

Research Products

Co-Researchers

骨芽細胞核におけるRunx2-Lamin Aの遺伝子発現制御機構の解明Principal Investigator

Principal Investigator

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Development of a new treatment for fibrodysplasia using active genomics and high-throughput analysis

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Multi-layered mutations in patient with Gorlin syndrome may affect the phenotype

Principal Investigator

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Elucidation of the regulatory mechanism of osteoblast differentiation based on a new concept and development of therapeutic agents for cleidocranial dysplasia.Principal Investigator

Principal Investigator

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Review Section

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Odontogenic keratocyst model using iPSCs derived from patient with Golin syndrome

Principal Investigator

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Review Section

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Elucidation of osteoblast mineralization mechanism using McCunealbright syndrome iPS cells

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Review Section

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Establishment and application of disease-specific iPS cells for Apert syndrome

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Establishment of iPS cells from McCune-Albright syndrome and it application

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Elucidation of the pathophysiology of cleidocranial dysplasia using disease-specific iPS cellsPrincipal Investigator

Principal Investigator

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Elucidation of the expression regulatory mechanism of tumor suppressor gene Lefty reprogrammed leukoplakia cellsPrincipal Investigator

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[Journal Article] FGF-2 promotes proliferation and consequently induces osteoblast differentiation in mesenchymal stem cells.2023

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[Journal Article] Current Status of Next-Generation Sequencing in Bone Genetic Diseases2023

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[Journal Article] Induced pluripotent stem cells from homozygous Runx2-deficient mice show poor response to vitamin D during osteoblastic differentiation2022

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DOI

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[Journal Article] Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages2022

Author(s)

Saito Akiko 齋藤暁子