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LIU Qinghua  Liu Qinghua

ORCIDConnect your ORCID iD *help
Researcher Number 90723792
Other IDs
Affiliation (based on the past Project Information) *help 2014 – 2022: 筑波大学, 国際統合睡眠医科学研究機構, 教授
2017: 筑波大学, 国際統合睡眠医科学研究機構, 教授(WPI-IIIS)
Review Section/Research Field
Principal Investigator
Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Complex systems / Molecular biology / Integrative animal science
Except Principal Investigator
Biological Sciences / Environmental physiology(including physical medicine and nutritional physiology) / Basic / Social brain science
Keywords
Principal Investigator
睡眠欲 / cFos / 心的外傷後ストレス障害 / ストレス / 麻酔 / 血糖値 / 眠気 / 神経回路 / 神経細胞 / 睡眠 … More / 恐怖 / 恐怖感情 / 意志力 / 核 酸 / RNA / 核酸 / siRNA / miRNA / Cryo-EM / RNAi / RISC / 恐怖情動 / バイオリソース / モデルマウス / 精神障害 / 先天的恐怖 / フォワード・ジェネティックス … More
Except Principal Investigator
睡眠 / 神経科学 / 細胞内シグナル / 睡眠覚醒 / 神経生理学 / マウス遺伝学 / 細胞内シグナル伝達 / ゲノムエディティング / 遺伝子改変マウス / 脳神経 / 睡眠・覚醒 / リン酸化酵素 / 細胞内シグナル伝達系 / ゲノム編集 / リン酸化 / 動物行動 / ジェネティクス / 睡眠障害 / フォワード・ジェネティックス / 生化学 Less
  • Research Projects

    (7 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (11 People)
  •  Understanding integrated sensing system of sleep pressurePrincipal Investigator

    • Principal Investigator
      Liu Qonghua
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      University of Tsukuba
  •  Elucidation of sleep/wakefulness regulation using forward genetic approach

    • Principal Investigator
      Yanagisawa Masashi
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  新規恐怖反応異常マウスで切り拓く恐怖感情と意志力のダイナミクスPrincipal Investigator

    • Principal Investigator
      Liu Qinghua
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      University of Tsukuba
  •  Involvement of nuclear transcription factor in RISC formation in RNA interferencePrincipal Investigator

    • Principal Investigator
      Liu Qinghua
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  Unveiling the molecular mechanism of innate fear using forward genetic screen approachPrincipal Investigator

    • Principal Investigator
      LIU Qinghua
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Integrative animal science
    • Research Institution
      University of Tsukuba
  •  フォワードジェネティクスで同定した新規睡眠制御遺伝子による睡眠覚醒制御機構の解明

    • Principal Investigator
      YANAGISAWA Masashi
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Basic / Social brain science
    • Research Institution
      University of Tsukuba
  •  フォワードジェネティクスで同定した新規睡眠制御遺伝子による睡眠覚醒制御機構の解明

    • Principal Investigator
      柳沢 正史
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      University of Tsukuba

All 2022 2021 2020 2019 2018 2017 2016 2014

All Journal Article Presentation

  • [Journal Article] Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice2021

    • Author(s)
      Can Liu, Chia-Ying Lee, Greg Asher, Liqin Cao, Yuka Terakoshi, Peng Cao, Reiko Kobayakawa, Ko Kobayakawa, Katsuyasu Sakurai, Qinghua Liu
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 2648-2648

    • DOI

      10.1038/s41467-021-22914-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06738, KAKENHI-PUBLICLY-19H05006, KAKENHI-PROJECT-18K06515, KAKENHI-PROJECT-17H06095, KAKENHI-PROJECT-20K20578, KAKENHI-PUBLICLY-20H04849
  • [Journal Article] Cerebral capillary blood flow upsurge during REM sleep is mediated by A2a receptors2021

    • Author(s)
      Tsai Chia-Jung、Nagata Takeshi、Liu Chih-Yao、Suganuma Takaya、Kanda Takeshi、Miyazaki Takehiro、Liu Kai、Saitoh Tsuyoshi、Nagase Hiroshi、Lazarus Michael、Vogt Kaspar E.、Yanagisawa Masashi、Hayashi Yu
    • Journal Title

      Cell Reports

      Volume: 36 Issue: 7 Pages: 109558-109558

    • DOI

      10.1016/j.celrep.2021.109558

    • NAID

      120007141681

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21456, KAKENHI-PROJECT-21K15617, KAKENHI-PROJECT-17H06095, KAKENHI-PUBLICLY-21H00199, KAKENHI-PUBLICLY-21H00414, KAKENHI-PROJECT-20H03353, KAKENHI-PROJECT-20K06922, KAKENHI-PROJECT-22KF0048, KAKENHI-PROJECT-23K21394
  • [Journal Article] Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep-Wake EEG Disturbances2020

    • Author(s)
      Tingting Lou, Jing Ma, Zhiqiang Wang, Yuka Terakoshi, Chia-Ying Lee, Greg Asher, Liqin Cao, Zhiyu Chen, Katsuyasu Sakurai, Qinghua Liu
    • Journal Title

      Frontiers in Neuroscience

      Volume: 14 Pages: 883-883

    • DOI

      10.3389/fnins.2020.00883

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06738, KAKENHI-PROJECT-19H03263, KAKENHI-PROJECT-18KK0070
  • [Journal Article] Effects of 3 Weeks of Water Immersion and Restraint Stress on Sleep in Mice.2019

    • Author(s)
      Yasugaki S, Liu CY, Kashiwagi M, Kanuka M, Honda T, Miyata S, Yanagisawa M, Hayashi Y.
    • Journal Title

      Frontiers in Neuroscience

      Volume: 13 Pages: 1072-1072

    • DOI

      10.3389/fnins.2019.01072

    • NAID

      120007132777

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06916, KAKENHI-PROJECT-17H06095, KAKENHI-PROJECT-17J00738
  • [Journal Article] Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors2018

    • Author(s)
      Wang, Y., Cao, L., Lee, C-Y., Matsuo, M., Wu, K., Asher, G., Saitoh, T., Klewe-Nebenius, D., Wang, L., Soya, S., Hasegawa, E., Cherasse, Y., Miyoshi,C., Irukayama, Y., Wang, Z., Sakurai, K., Funato, H., Sakurai, T., Yanagisawa, M., Nagase, H., Kobayakawa, R., Kobayakawa, K., Beutler, B., Liu, Q
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 2041-2041

    • DOI

      10.1038/s41467-018-04324-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08133, KAKENHI-PROJECT-17H06095, KAKENHI-PLANNED-15H05942, KAKENHI-PUBLICLY-17H05583, KAKENHI-PUBLICLY-17H06048, KAKENHI-PROJECT-17H04023, KAKENHI-PROJECT-16K07445, KAKENHI-PUBLICLY-17H05586, KAKENHI-PUBLICLY-18H04806, KAKENHI-PROJECT-16H02591, KAKENHI-PROJECT-18H02546, KAKENHI-PROJECT-18K19350, KAKENHI-PROJECT-18K06024
  • [Journal Article] Quantitative phosphoproteomic analysis of the molecular substrates of sleep need2018

    • Author(s)
      Z. Wang, J. Ma, C. Miyoshi, Y. Li, M Sato, Y. Ogawa, T. Lou, C. Ma, X. Gao, C. Lee, T. Fujiyama, X. Yang, S. Zhou, N. Hotta-Hirashima, D. Klewe-Nebenus, A. Ikkyu, M. Kakizaki, S. Kanno, L. Cao, S. Takahashi, J. Peng, Y. Yu, H. Funato, M. Yanagisawa, Q. Liu
    • Journal Title

      Nature

      Volume: 558 Issue: 7710 Pages: 435-439

    • DOI

      10.1038/s41586-018-0218-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08133, KAKENHI-PROJECT-17K15592, KAKENHI-PROJECT-17H06095, KAKENHI-PLANNED-15H05942, KAKENHI-PUBLICLY-17H05583, KAKENHI-PUBLICLY-17H06048, KAKENHI-PROJECT-17H04023, KAKENHI-PROJECT-18K06024, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Forward-genetics analysis of sleep in randomly mutagenized mice2016

    • Author(s)
      Funato H and Yanagisawa M et al.
    • Journal Title

      Nature

      Volume: 539(7629) Issue: 46 Pages: 378-383

    • DOI

      10.1038/nature20142

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-15J06369, KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-26507003, KAKENHI-PROJECT-26507008, KAKENHI-PROJECT-15K18966, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16K15187, KAKENHI-PROJECT-16K16639, KAKENHI-PROJECT-16K18358, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015, KAKENHI-PROJECT-16H00588, KAKENHI-PROJECT-16H00590, KAKENHI-PROJECT-15J00393
  • [Journal Article] HP1BP3, a chromatin retention factor for co-transcriptional microRNA processing2016

    • Author(s)
      H. Liu#, C. Liang#, R.K. Kollipara, M. Matsui, X. Ke, B-C. Jeong, Z. Wang, K.S. Yoo, G.P. Yadav, L.N. Kinch, N.V. Grishin, Y. Nam, D.R. Corey, R. Kittler, Q.Liu.
    • Journal Title

      Mol Cell

      Volume: 63 Pages: 420-432

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04740
  • [Journal Article] Orexin/Hypocretin Activates mTOR Complex 1 (mTORC1) via an Erk/Akt-independent and Calcium-stimulated Lysosome v-ATPase Pathway2014

    • Author(s)
      Zhiqiang Wang, Shimeng Liu, Miyo Kakizaki, Yuuki Hirose, Yukiko Ishikawa, Hiromasa Funato, Masashi Yanagisawa, Yonghao Yu,Qinghua Liu
    • Journal Title

      Journal of Biological Chemistry

      Volume: 289 Issue: 46 Pages: 31950-31959

    • DOI

      10.1074/jbc.m114.600015

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-25126725, KAKENHI-PROJECT-25460318, KAKENHI-PROJECT-26220207
  • [Presentation] Natural history study of sleep disturbances in CDKL5 deficiency disorder mice2022

    • Author(s)
      Cao Liqin, Tingting Lou, Xin Zhang, Jing Ma, Zhiqiang Wang, Teruyuki Tanaka, Hiromasa Funato, Qinghua Liu, Masashi Yanagisawa
    • Organizer
      第99回日本生理学会JST-CREST "Opt Bio" /WPI-IIIS Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06095
  • [Presentation] Molecular Substrates of Homeostatic Sleep Regulation2020

    • Author(s)
      Qinghua Liu
    • Organizer
      25th Congress of the European Sleep Research Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06095
  • [Presentation] Molecular Circuits of Homeostatic Sleep Regulation2020

    • Author(s)
      Qinghua Liu
    • Organizer
      Society for Research on Biological Rhythm (SRBR) 2020 biennial conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06095
  • [Presentation] Identifying schizophrenia genes through a forward genetic screen in mice2019

    • Author(s)
      Liqin Cao, Daniela Klewe-Nebenius, Greg Asher, Chika Miyoshi, Takeshi Sakurai, Hiromasa Funato, Masashi Yanagisawa, Qinghua Liu
    • Organizer
      Neuro2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06095
  • [Presentation] Quantitative phosphoproteomic analysis of the molecular substrates of sleep need2018

    • Author(s)
      Liu Qinghua
    • Organizer
      Texas Society for Circadian Biology and Medicine meeting
    • Data Source
      KAKENHI-PROJECT-16H04740
  • [Presentation] Cumulative phosphorylation of SNIPPs as a function of homeostatic sleep need2018

    • Author(s)
      Liu Qinghua
    • Organizer
      Gordon Research Conference on Sleep Regulation and Function, Galveston, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04740
  • [Presentation] Psycho, a potential mouse model of schizophrenia2018

    • Author(s)
      Liqin Cao, Daniela Klewe-Nebenius, Greg Asher, Makito Sato, Chika Miyoshi, Hiromasa Funato, Masashi Yanagisawa, Qinghua Liu
    • Organizer
      The 7th Annual IIIS International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H06048
  • [Presentation] A synaptic phosphoproteomic link to homeostatic sleep need2017

    • Author(s)
      Liu Qinghua
    • Organizer
      40th Annual meeting of the Japan Neuroscience Society, Chiba, Japan
    • Data Source
      KAKENHI-PROJECT-16H04740
  • [Presentation] Identification of molecular correlates of sleep need by phosphoproteomic analysis2017

    • Author(s)
      Qinghua Liu
    • Organizer
      Circadian and sleep medicine symposium
    • Place of Presentation
      Dallas, TX, (USA)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26220207
  • [Presentation] Synaptic phosphoproteome as a molecular correlate of sleep need2017

    • Author(s)
      Liu Qinghua
    • Organizer
      Asian Chronobiology Forum and 2nd Biennial conference of Chinese Society of Biological Rhythms, Hohhot, China
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04740
  • [Presentation] A molecular link between synaptic phosphoproteome and homeostatic sleep need2017

    • Author(s)
      Liu Qinghua
    • Organizer
      Cold Spring Harbor Asia meeting Francis Crick Frontier in Neuroscience, Suzhou, China
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04740
  • [Presentation] HP1BP3, a chromatin retention factor for co-transcriptional microRNA processing2016

    • Author(s)
      Qinghua Liu
    • Organizer
      International RNA society meeting in Kyoto
    • Place of Presentation
      Kyoto international conference center (kyoto city)
    • Year and Date
      2016-06-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04740
  • 1.  YANAGISAWA Masashi (20202369)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 2.  船戸 弘正 (90363118)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 3.  上田 壮志 (00599821)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  高橋 智 (50271896)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KOBAYAKAWA Reiko (40372411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  曹 麗琴 (60399475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  クレウエ・ネベニウス ダニエラ (60737667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  佐藤 牧人 (70743699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  櫻井 勝康 (70507920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MIYATA Shingo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  HAYASHI Yu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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