ISHIHARA TOMOAKI 石原知明

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石原知明イシハラトモアキ

Ishihara Tomoaki 石原知明

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Researcher Number	90724013
Other IDs	https://orcid.org/0000-0002-0840-008X
Affiliation (Current)	2025: 長崎国際大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2025: 長崎国際大学, 薬学部, 講師 2022 – 2023: 長崎国際大学, 薬学部, 講師 2018: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Genome biology
Keywords	Principal Investigator 脂質 / 代謝異常 / 老化関連疾患 / リピドミクス / 細胞老化 / オートファジー / 脂質代謝酵素 / 老化 / 薬理学 / 分析科学 … More / 生理活性 / 酵素 / シトクロムP450 / 機能性代謝物 / シトクロムP450（Cyp） / エイコサペンタエン酸 / 17,18-EpETE / EPA / 生体恒常性 / チトクロムP450 / 活性代謝物 / 脂肪酸代謝酵素 / ω3脂肪酸 Less

老化に伴い増加するビスモノアシルグリセロリン酸によるオートファジー制御機構の解明Principal Investigator
- Principal Investigator
  
  石原知明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki International University
老化に伴い発現する脂質代謝異常とその生理学的役割の解明Principal Investigator
- Principal Investigator
  
  石原知明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki International University
Comprehensive analysis of the metabolic pathway involved in the biological function of omega-3 fatty acidsPrincipal Investigator
- Principal Investigator
  
  Ishihara Tomoaki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genome biology
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2022 2019 2018 2017

All Journal Article Presentation

[Journal Article] A lipidome landscape of aging in mice2024
- Author(s)
  Tsugawa Hiroshi、Ishihara Tomoaki、Ogasa Kota、Iwanami Seigo、Hori Aya、Takahashi Mikiko、Yamada Yutaka、Satoh-Takayama Naoko、Ohno Hiroshi、Minoda Aki、Arita Makoto
- Journal Title
  
  Nature Aging
  
  Volume: 4 Issue: 5 Pages: 709-726
- DOI
  10.1038/s43587-024-00610-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11718, KAKENHI-PROJECT-21K18216, KAKENHI-PROJECT-20KK0360
[Journal Article] Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis2022
- Author(s)
  Mio Yoshida, Tomoaki Ishihara, Yosuke Isobe, Makoto Arita
- Journal Title
  
  FASEB Journal
  
  Volume: 36(12) Issue: 12
- DOI
  10.1096/fj.202200982r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11718, KAKENHI-PROJECT-20H00495
[Journal Article] Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis2019
- Author(s)
  Ishihara Tomoaki、Yoshida Mio、Arita Makoto
- Journal Title
  
  International Immunology
  
  Volume: - Issue: 9 Pages: 559-567
- DOI
  10.1093/intimm/dxz001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-17K18364, KAKENHI-ORGANIZER-15H05897
[Journal Article] ω３脂肪酸由来脂質メディエーターと炎症制御2018
- Author(s)
  吉田美桜、礒部洋輔、石原知明、有田誠
- Journal Title
  
  細胞
  
  Volume: 50 Pages: 8-12
- Data Source
  KAKENHI-PROJECT-17K18364
[Journal Article] Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid2018
- Author(s)
  Isobe Yosuke、Kawashima Yusuke、Ishihara Tomoaki、Watanabe Kenji、Ohara Osamu、Arita Makoto
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 13 Issue: 4 Pages: 887-893
- DOI
  10.1021/acschembio.7b01092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18360, KAKENHI-PROJECT-17K18364, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898
[Journal Article] ω3脂肪酸の代謝と抗炎症作用2017
- Author(s)
  石原知明, 磯部洋輔, 有田誠
- Journal Title
  
  ビタミン
  
  Volume: 91 Pages: 537-541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18364
[Presentation] Protective role of omega-3 fatty acid oxygenase in skin homeostasis2018
- Author(s)
  Tomoaki Ishihara
- Organizer
  The Annual Meeting of Aging Project 2018
- Data Source
  KAKENHI-PROJECT-17K18364
[Presentation] 皮膚の組織恒常性における脂肪酸代謝系の関与2017
- Author(s)
  石原　知明, 磯部　洋輔, 吉田　美桜, 板垣　舞, 有田　誠
- Organizer
  第42回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-17K18364
[Presentation] Emerging roles of fatty acid metabolism in tissue homeostasis and aging2017
- Author(s)
  Tomoaki Ishihara
- Organizer
  Young researchers workshop Integrated life science research to challenge super aging society
- Data Source
  KAKENHI-PROJECT-17K18364

1. Arita Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. Ikeda Kazutaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 川島祐介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 有田正規

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIHARA TOMOAKI 石原 知明

石原 知明 イシハラ トモアキ

Ishihara Tomoaki 石原 知明

Research Projects

Research Products

Co-Researchers

老化に伴い増加するビスモノアシルグリセロリン酸によるオートファジー制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

老化に伴い発現する脂質代謝異常とその生理学的役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of the metabolic pathway involved in the biological function of omega-3 fatty acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A lipidome landscape of aging in mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ω３脂肪酸由来脂質メディエーターと炎症制御2018

Author(s)

Journal Title

Data Source

[Journal Article] Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ω3脂肪酸の代謝と抗炎症作用2017

Author(s)

Journal Title

Data Source

[Presentation] Protective role of omega-3 fatty acid oxygenase in skin homeostasis2018

Author(s)

Organizer

Data Source

[Presentation] 皮膚の組織恒常性における脂肪酸代謝系の関与2017

Author(s)

Organizer

Data Source

[Presentation] Emerging roles of fatty acid metabolism in tissue homeostasis and aging2017

Author(s)

Organizer

Data Source

ISHIHARA TOMOAKI 石原知明

石原知明イシハラトモアキ

Ishihara Tomoaki 石原知明