ISHIHARA TOMOAKI 石原知明

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Ishihara Tomoaki 石原知明

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Researcher Number	90724013
Other IDs	https://orcid.org/0000-0002-0840-008X
Affiliation (Current)	2024: 長崎国際大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 長崎国際大学, 薬学部, 講師 2018: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Genome biology
Keywords	Principal Investigator 脂質 / 代謝異常 / 老化関連疾患 / リピドミクス / 細胞老化 / オートファジー / 脂質代謝酵素 / 老化 / 薬理学 / 分析科学 … More / 生理活性 / 酵素 / シトクロムP450 / 機能性代謝物 / シトクロムP450（Cyp） / エイコサペンタエン酸 / 17,18-EpETE / EPA / 生体恒常性 / チトクロムP450 / 活性代謝物 / 脂肪酸代謝酵素 / ω3脂肪酸 Less

老化に伴い発現する脂質代謝異常とその生理学的役割の解明Principal Investigator
- Principal Investigator
  
  石原知明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki International University
Comprehensive analysis of the metabolic pathway involved in the biological function of omega-3 fatty acidsPrincipal Investigator
- Principal Investigator
  
  Ishihara Tomoaki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genome biology
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2022 2019 2018 2017

All Journal Article Presentation

[Journal Article] A lipidome landscape of aging in mice2024
- Author(s)
  Tsugawa Hiroshi、Ishihara Tomoaki、Ogasa Kota、Iwanami Seigo、Hori Aya、Takahashi Mikiko、Yamada Yutaka、Satoh-Takayama Naoko、Ohno Hiroshi、Minoda Aki、Arita Makoto
- Journal Title
  
  Nature Aging
  
  Volume: 4 Issue: 5 Pages: 709-726
- DOI
  10.1038/s43587-024-00610-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11718, KAKENHI-PROJECT-21K18216, KAKENHI-PROJECT-20KK0360
[Journal Article] Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis2022
- Author(s)
  Mio Yoshida, Tomoaki Ishihara, Yosuke Isobe, Makoto Arita
- Journal Title
  
  FASEB Journal
  
  Volume: 36(12) Issue: 12
- DOI
  10.1096/fj.202200982r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11718, KAKENHI-PROJECT-20H00495
[Journal Article] Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis2019
- Author(s)
  Ishihara Tomoaki、Yoshida Mio、Arita Makoto
- Journal Title
  
  International Immunology
  
  Volume: - Issue: 9 Pages: 559-567
- DOI
  10.1093/intimm/dxz001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-17K18364, KAKENHI-ORGANIZER-15H05897
[Journal Article] ω３脂肪酸由来脂質メディエーターと炎症制御2018
- Author(s)
  吉田美桜、礒部洋輔、石原知明、有田誠
- Journal Title
  
  細胞
  
  Volume: 50 Pages: 8-12
- Data Source
  KAKENHI-PROJECT-17K18364
[Journal Article] Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid2018
- Author(s)
  Isobe Yosuke、Kawashima Yusuke、Ishihara Tomoaki、Watanabe Kenji、Ohara Osamu、Arita Makoto
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 13 Issue: 4 Pages: 887-893
- DOI
  10.1021/acschembio.7b01092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18360, KAKENHI-PROJECT-17K18364, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898
[Journal Article] ω3脂肪酸の代謝と抗炎症作用2017
- Author(s)
  石原知明, 磯部洋輔, 有田誠
- Journal Title
  
  ビタミン
  
  Volume: 91 Pages: 537-541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18364
[Presentation] Protective role of omega-3 fatty acid oxygenase in skin homeostasis2018
- Author(s)
  Tomoaki Ishihara
- Organizer
  The Annual Meeting of Aging Project 2018
- Data Source
  KAKENHI-PROJECT-17K18364
[Presentation] 皮膚の組織恒常性における脂肪酸代謝系の関与2017
- Author(s)
  石原　知明, 磯部　洋輔, 吉田　美桜, 板垣　舞, 有田　誠
- Organizer
  第42回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-17K18364
[Presentation] Emerging roles of fatty acid metabolism in tissue homeostasis and aging2017
- Author(s)
  Tomoaki Ishihara
- Organizer
  Young researchers workshop Integrated life science research to challenge super aging society
- Data Source
  KAKENHI-PROJECT-17K18364

1. Arita Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. Ikeda Kazutaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 川島祐介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 有田正規

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIHARA TOMOAKI 石原 知明

Ishihara Tomoaki 石原 知明

Research Projects

Research Products

Co-Researchers

老化に伴い発現する脂質代謝異常とその生理学的役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of the metabolic pathway involved in the biological function of omega-3 fatty acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A lipidome landscape of aging in mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ω３脂肪酸由来脂質メディエーターと炎症制御2018

Author(s)

Journal Title

Data Source

[Journal Article] Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ω3脂肪酸の代謝と抗炎症作用2017

Author(s)

Journal Title

Data Source

[Presentation] Protective role of omega-3 fatty acid oxygenase in skin homeostasis2018

Author(s)

Organizer

Data Source

[Presentation] 皮膚の組織恒常性における脂肪酸代謝系の関与2017

Author(s)

Organizer

Data Source

[Presentation] Emerging roles of fatty acid metabolism in tissue homeostasis and aging2017

Author(s)

Organizer

Data Source

ISHIHARA TOMOAKI 石原知明

Ishihara Tomoaki 石原知明