Yoshida Hisashi 吉田尚史

Researcher Number	90724774
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 筑波大学, 生存ダイナミクス研究センター, 助教 2020: 横浜市立大学, 生命医科学研究科, 特任助教 2016: 公益財団法人神奈川科学技術アカデミー, 革新的インフルエンザウイルス創薬プロジェクト, 研究員 2015: 公益財団法人神奈川科学技術アカデミー, 朴プロジェクト, 研究員
Review Section/Research Field	Principal Investigator Basic Section 38030:Applied biochemistry-related / Basic Section 49060:Virology-related / Structural biochemistry
Keywords	Principal Investigator X線結晶構造解析 / インフルエンザウイルス / マイナーイントロン / SRSF2 / ZRSR2 / pre-mRNA / 骨髄異形成症候群 / スプライシング / 立体構造解析 / クライオ電子顕微鏡解析 … More / 増殖阻害抗体 / RNAポリメラーゼ / インフルエンザ / ITC / インフルエンザRNAポリメラーゼ / クライオ電子顕微鏡 / 阻害抗体 / NP / 核移行 / 宿主因子 / 核輸送 Less

マイナーイントロンスプライシングにおけるZRSR2のRNA認識機構の解明Principal Investigator
- Principal Investigator
  
  吉田尚史
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  University of Tsukuba
Structural analysis of Influenza viral RNA polymerase and inhibitory antibodyPrincipal Investigator
- Principal Investigator
  
  Yoshida Hisashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  University of Tsukuba
  Yokohama City University
Structural Study of Influenza Virral NP and importin5 of Host Cell Factor.Principal Investigator
- Principal Investigator
  
  Yoshida Hisashi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kanagawa Academy of Science and Technology

All 2023 2022 2017 2015

All Journal Article Presentation

[Journal Article] Structural insights into the HBV receptor and bile acid transporter NTCP2022
- Author(s)
  Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY.
- Journal Title
  
  Nature
  
  Volume: 606 Issue: 7916 Pages: 1027-1031
- DOI
  10.1038/s41586-022-04857-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15453, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-21H02449, KAKENHI-PROJECT-20K16264, KAKENHI-PLANNED-19H05779, KAKENHI-PLANNED-19H05777
[Journal Article] G196 epitope tag system: a novel monocle antibody, G196, recognizes the small, soluble peptide DLVPR with high affinity2017
- Author(s)
  Tatsumi K, Sakashita G, Nariai Y, Okazaki K, Kato H, Obayashi E, Yoshida H, Sugiyama K, Park SY, Sekine J, Urano T
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 43480-43480
- DOI
  10.1038/srep43480
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18499
[Journal Article] Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF52017
- Author(s)
  Obayashi E, Luna RE, Nagata T, Martin-Marcos P, Hiraishi H, Singh CR, Erzberger JP, Zhang F, Arthanari H, Morris J, Pellarin R, Moore C, Harmon I, Papadopoulos E, Yoshida H, Nasr ML, Unzai S, Thompson B, Aube E, Hustak S, Stengel F, Dagraca E, Ananbandam A, Gao P, Urano T, Hinnebusch AG, Wagner G, Asano K.
- Journal Title
  
  Cell Report
  
  Volume: 18 Issue: 11 Pages: 2651-2663
- DOI
  10.1016/j.celrep.2017.02.052
- NAID
  120006358788
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01634, KAKENHI-PROJECT-15K18499, KAKENHI-PROJECT-15K06980, KAKENHI-PROJECT-26440026
[Journal Article] A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.2015
- Author(s)
  Yoshida H, Park S-Y, Oda T, Akiyoshi T, Sato M, Shirouzu M, Tsuda K, Kuwasako K, Unzai S, Muto Y, Urano T, Obayashi E.
- Journal Title
  
  Genes Dev.
  
  Volume: 29 Issue: 15 Pages: 1649-1660
- DOI
  10.1101/gad.267104.115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06980, KAKENHI-PROJECT-15K06982, KAKENHI-PROJECT-15K18499, KAKENHI-PUBLICLY-26116519, KAKENHI-PROJECT-25291016, KAKENHI-PROJECT-25291037
[Presentation] スプライシング異常を伴う骨髄異形成症候群におけるSRSF2変異体の結晶構造解析2023
- Author(s)
  佐藤理央、吉永匡希、尾林栄治、岩崎憲治、吉田尚史
- Organizer
  量子ビームサインエスフェスタ
- Data Source
  KAKENHI-PROJECT-22K05424
[Presentation] スプライシング異常を伴う骨髄異形成症候群におけるSRSF2変異体の結晶構造解析2023
- Author(s)
  川本江那、佐藤理央、吉永匡希、朴三用、尾林栄治、吉田尚史
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K05424
[Presentation] スプライシングタンパク質U2AF1によるイントロン認識機構の解明2022
- Author(s)
  吉田尚史, 朴三用, 坂下暁介, 成相裕子, 桑迫香奈子, 武藤裕, 浦野健, 尾林栄治
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K05424
[Presentation] The Structural basis of 3' splice site recognition by splicing factor U2AF12022
- Author(s)
  吉田尚史, 朴三用, 坂下暁介, 成相裕子, 桑迫香奈子, 武藤裕, 浦野健, 尾林栄治
- Organizer
  第23回RNA学会年会
- Data Source
  KAKENHI-PROJECT-22K05424

1. NAGATA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 岩本将士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 朴三用

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 雲財悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshida Hisashi 吉田 尚史

Research Projects

Research Products

Co-Researchers

マイナーイントロンスプライシングにおけるZRSR2のRNA認識機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analysis of Influenza viral RNA polymerase and inhibitory antibodyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural Study of Influenza Virral NP and importin5 of Host Cell Factor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Structural insights into the HBV receptor and bile acid transporter NTCP2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] G196 epitope tag system: a novel monocle antibody, G196, recognizes the small, soluble peptide DLVPR with high affinity2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF52017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] スプライシング異常を伴う骨髄異形成症候群におけるSRSF2変異体の結晶構造解析2023

Author(s)

Organizer

Data Source

[Presentation] スプライシング異常を伴う骨髄異形成症候群におけるSRSF2変異体の結晶構造解析2023

Author(s)

Organizer

Data Source

[Presentation] スプライシングタンパク質U2AF1によるイントロン認識機構の解明2022

Author(s)

Organizer

Data Source

[Presentation] The Structural basis of 3' splice site recognition by splicing factor U2AF12022

Author(s)

Organizer

Data Source

Yoshida Hisashi 吉田尚史