Baird Liam ＢａｉｒｄＬｉａｍ

Researcher Number	90724914
Other IDs
Affiliation (Current)	2025: 東北大学, 未来型医療創成センター, 助教
Affiliation (based on the past Project Information) *help	2025: 東北大学, 未来型医療創成センター, 助教 2017 – 2020: 東北大学, 医学系研究科, 助教 2016: 東北大学, 知の創出センター, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / General medical chemistry
Keywords	Principal Investigator Keap1-Nrf2 / Environmental stress / Nrf2 / Keap1 / synthetic lethal / Molecular Biology / 細胞内シグナル伝達

Elucidation of the molecular mechanism of environmental stress response-mediated regulation of inflammationPrincipal Investigator
- Principal Investigator
  
  Baird Liam
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tohoku University
Development of an Nrf2 inhibitor for the treatment of Nrf2-addicted cancerPrincipal Investigator
- Principal Investigator
  
  Baird Liam
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tohoku University
An investigation into the mechanism regulating the oxidative stress-dependent activation of the Keap1-Nrf2 pathwayPrincipal Investigator
- Principal Investigator
  
  Baird Liam
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University

All 2020 2017

All Journal Article

[Journal Article] Geldanamycin-derived HSP90 inhibitors are synthetic lethal with NRF22020
- Author(s)
  Baird Liam、Suzuki Takafumi、Takahashi Yushi、Hishinuma Eiji、Saigusa Daisuke、Yamamoto Masayuki
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 40 Issue: 22 Pages: 1-22
- DOI
  10.1128/mcb.00377-20
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19K16512
[Journal Article] NRF2-Dependent Bioactivation of Mitomycin C as a Novel Strategy To Target KEAP1-NRF2 Pathway Activation in Human Cancer2020
- Author(s)
  Baird Liam、Yamamoto Masayuki
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 41 Issue: 2 Pages: 1-18
- DOI
  10.1128/mcb.00473-20
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19K16512
[Journal Article] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway2020
- Author(s)
  Baird Liam、Yamamoto Masayuki
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 40 Issue: 13 Pages: 1-23
- DOI
  10.1128/mcb.00099-20
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19K16512
[Journal Article] Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.2017
- Author(s)
  Suzuki T, Seki S, Hiramoto K, Naganuma E, Kobayashi EH, Yamaoka A, Baird L, Takahashi N, Sato H, Yamamoto M.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 14577-14577
- DOI
  10.1038/ncomms14577
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-16K19027, KAKENHI-PROJECT-17K15590

1. Yamamoto Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. Suzuki Takafumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SUZUKI Norio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Baird Liam Ｂａｉｒｄ Ｌｉａｍ

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanism of environmental stress response-mediated regulation of inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of an Nrf2 inhibitor for the treatment of Nrf2-addicted cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An investigation into the mechanism regulating the oxidative stress-dependent activation of the Keap1-Nrf2 pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Geldanamycin-derived HSP90 inhibitors are synthetic lethal with NRF22020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NRF2-Dependent Bioactivation of Mitomycin C as a Novel Strategy To Target KEAP1-NRF2 Pathway Activation in Human Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.2017

Author(s)

Journal Title

DOI

Data Source

Baird Liam ＢａｉｒｄＬｉａｍ