Uriu Koichiro 瓜生耕一郎

Researcher Number	90726241
Other IDs
External Links
Affiliation (Current)	2025: 東京科学大学, 生命理工学院, 准教授
Affiliation (based on the past Project Information) *help	2024: 東京工業大学, 生命理工学院, 准教授 2018 – 2023: 金沢大学, 生命理工学系, 助教 2015 – 2017: 金沢大学, 自然システム学系, 助教 2014: 独立行政法人理化学研究所, 階層縦断型理論生物学研究チーム, 研究員
Review Section/Research Field	Principal Investigator Biological Sciences / Transformative Research Areas, Section (III) / Basic Section 44020:Developmental biology-related / Complex systems / Developmental biology Except Principal Investigator Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related / Basic Section 45020:Evolutionary biology-related / Basic Section 45010:Genetics-related / Transformative Research Areas, Section (III)
Keywords	Principal Investigator 数理モデル / 同期 / 体節形成 / ゼブラフィッシュ / 分節時計 / 遺伝子発現リズム / 位相振動子 / 細胞移動 / 記憶 / sharp-wave/ripples … More / 海馬 / 数理生物学 / 非線型システム / 哺乳類概日時計 / 光応答 / Period / リミットサイクル / 位相応答 / 概日時計 / 発生・分化 / 発生 / ロンドン / ブエノスアイレス / 国際情報交換 / 数値シミュレーション / cell mixing / トラッキング / シミュレーション / 時間スケール / 画像解析 … More Except Principal Investigator 位相前進作用 / 概日リズム / 内的脱同調 / 時計遺伝子 / 数理モデル / 大規模電気生理 / 多光子イメージング / 睡眠行動解析 / 眠気 Less

眠気の生成・解消機構の解明のための総括研究
- Principal Investigator
  
  丹羽康貴
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Hirosaki University
細胞状態遷移と神経回路遷移をつなぐ数理モデル: 眠気の生成・解消機構の理論Principal Investigator
- Principal Investigator
  
  瓜生耕一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Science Tokyo
Period1誘導化合物の位相前進作用の解明とそれを用いた内的脱同調モデルの構築
- Principal Investigator
  
  程肇
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45010:Genetics-related
  Basic Section 45020:Evolutionary biology-related
  Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related
- Research Institution
  Kanazawa University
Analysis of gene expression rhythms in a population of mobile cellsPrincipal Investigator
- Principal Investigator
  
  Uriu Koichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kanazawa University
Synchronization of developmental clock under tissue deformationPrincipal Investigator
- Principal Investigator
  
  瓜生耕一郎
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Phase response theory of the circadian clocks and its experimental validationPrincipal Investigator
- Principal Investigator
  
  瓜生耕一郎
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kanazawa University
Spatiotemporal dynamics of developmental clocks: mathematical modeling of resynchronization process of the segmentation clockPrincipal Investigator
- Principal Investigator
  
  瓜生耕一郎
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Mathematical modeling of collective cell movementPrincipal Investigator
- Principal Investigator
  
  Uriu Koichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Kanazawa University
  The Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation2023
- Author(s)
  Yabe Taijiro、Uriu Koichiro、Takada Shinji
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2115-2115
- DOI
  10.1038/s41467-023-37745-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02498, KAKENHI-PROJECT-20K06653, KAKENHI-PUBLICLY-22H05642
[Journal Article] Orchestration of tissue shape changes and gene expression patterns in development.2023
- Author(s)
  Uriu K, Morelli LG.
- Journal Title
  
  Semin. Cell Dev. Biol.
  
  Volume: 147 Pages: 24-33
- DOI
  10.1016/j.semcdb.2022.12.009
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06653
[Journal Article] Cell size homeostasis under the circadian regulation of cell division in cyanobacteria.2022
- Author(s)
  Kitaguchi Y, Tei H, Uriu K.
- Journal Title
  
  J. Theor. Biol.
  
  Volume: 553 Pages: 111260-111260
- DOI
  10.1016/j.jtbi.2022.111260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06653
[Journal Article] From local resynchronization to global pattern recovery in the zebrafish segmentation clock2021
- Author(s)
  Uriu K., Liao B-K., Oates A.C., Morelli L.G.
- Journal Title
  
  Elife
  
  Volume: 10
- DOI
  10.7554/elife.61358
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04772
[Journal Article] Complementary phase responses via functional differentiation of dual negative feedback loops2021
- Author(s)
  Uriu K. and Tei H.
- Journal Title
  
  PLOS Computational Biology
  
  Volume: 17 Issue: 3 Pages: e1008774-e1008774
- DOI
  10.1371/journal.pcbi.1008774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04955
[Journal Article] Synchronization dynamics of mobile oscillators in the presence of coupling delays2019
- Author(s)
  Petrungaro G., Uriu K., Morelli L.G.
- Journal Title
  
  Physical Review E
  
  Volume: 99 Issue: 6
- DOI
  10.1103/physreve.99.062207
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04772
[Journal Article] A saturated reaction in repressor synthesis creates a daytime dead zone in circadian clocks2019
- Author(s)
  Uriu K., Tei H.
- Journal Title
  
  PLoS Comput Biol.
  
  Volume: 15 Issue: 2 Pages: e1006787-e1006787
- DOI
  10.1371/journal.pcbi.1006787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Journal Article] Information flow in the presence of cell mixing and signaling delays during embryonic development2018
- Author(s)
  Petrungaro G., Morelli L.G., Uriu K.
- Journal Title
  
  Semin Cell Dev Biol.
  
  Volume: - Pages: 26-35
- DOI
  10.1016/j.semcdb.2018.09.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Journal Article] Assessment of instructions on protection against food contaminated with radiocesium in Japan in 20112018
- Author(s)
  Seto M., Uriu K., Kawaguchi I., Yokomizo H.
- Journal Title
  
  Risk Anal.
  
  Volume: 印刷中 Issue: 6 Pages: 1154-1168
- DOI
  10.1111/risa.12893
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Journal Article] A framework for quantification and physical modeling of cell mixing applied to oscillator synchronization in vertebrate somitogenesis2017
- Author(s)
  Uriu K., Bhavna R. Oates A.C., Morelli L.G.
- Journal Title
  
  Biol. Open
  
  Volume: 6 Pages: 1235-1244
- DOI
  10.1242/bio.025148
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Journal Article] Feedback loops interlocked at competitive binding sites amplify and facilitate genetic oscillations2017
- Author(s)
  Uriu K., Tei H.
- Journal Title
  
  J. Theor. Biol.
  
  Volume: 428 Pages: 56-64
- DOI
  10.1016/j.jtbi.2017.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Journal Article] Determining the impact of cell mixing on signaling during development2017
- Author(s)
  Uriu K., Morelli L.G.
- Journal Title
  
  Dev. Growth Differ.
  
  Volume: 59 Issue: 5 Pages: 351-368
- DOI
  10.1111/dgd.12366
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Journal Article] Mobility-induced persistent chimera states2017
- Author(s)
  Petrungaro G., Uriu K., Morelli L.G.
- Journal Title
  
  Phys. Rev. E
  
  Volume: 96 Issue: 6 Pages: 062210-062210
- DOI
  10.1103/physreve.96.062210
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Journal Article] Object segmentation and ground truth in 3D embryonic imaging2016
- Author(s)
  Bhavna Rajasekaran, Koichiro Uriu, Guillaume Valentin, Jean-Yves Tinevez, Andrew C. Oates
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 6 Pages: e0150853-e0150853
- DOI
  10.1371/journal.pone.0150853
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840085
[Journal Article] Genetic oscillators in development2016
- Author(s)
  Koichiro Uriu
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 58 Issue: 1 Pages: 16-30
- DOI
  10.1111/dgd.12262
- NAID
  120005741598
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26840085
[Journal Article] Interplay between intercellular signaling and cell movement in development2014
- Author(s)
  Koichiro Uriu, Luis G. Morelli and Andrew C. Oates
- Journal Title
  
  Seminars in Cell and Developmental Biology
  
  Volume: 35 Pages: 66-72
- DOI
  10.1016/j.semcdb.2014.05.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26840085
[Journal Article] Collective cell movement promotes synchronization of coupled genetic oscillators2014
- Author(s)
  Koichiro Uriu and Luis G. Morelli
- Journal Title
  
  Biophysical Journal
  
  Volume: 107 Issue: 2 Pages: 514-526
- DOI
  10.1016/j.bpj.2014.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Bifurcation for determining somite boundary in zebrafish2022
- Author(s)
  Koichiro Uriu, Taijiro Yabe, Shinji Takada
- Organizer
  日本数理生物学会2022年年会
- Data Source
  KAKENHI-PROJECT-20K06653
[Presentation] Regularity of gene expression waves under cell mobility gradient in somitogenesis2022
- Author(s)
  Koichiro Uriu, Luis Morelli
- Organizer
  第55回日本発生生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06653
[Presentation] Synchronization dynamics of the zebrafish segmentation clock: effect of delayed coupling and period gradient.2021
- Author(s)
  Koichiro Uriu
- Organizer
  第54回日本発生生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06653
[Presentation] From local synchronization by Delta-Notch signaling to global pattern formation2021
- Author(s)
  Koichiro Uriu
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06653
[Presentation] Continuum limit of mobile genetic oscillators in vertebrate segment formation2021
- Author(s)
  Koichiro Uriu
- Organizer
  第31回日本数理生物学会大会
- Data Source
  KAKENHI-PROJECT-20K06653
[Presentation] 二重ネガティブフィードバックループの機能分化がもたらす概日時計の相補的位相応答2020
- Author(s)
  瓜生耕一郎
- Organizer
  2020年日本数理生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04955
[Presentation] 概日時計システムにおけるネガティブフィードバックループの機能分化2020
- Author(s)
  瓜生耕一郎
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04955
[Presentation] 哺乳類Period遺伝子の機能分化による相補的な位相応答2020
- Author(s)
  瓜生耕一郎
- Organizer
  第27回日本時間生物学会学術大会
- Data Source
  KAKENHI-PUBLICLY-19H04955
[Presentation] Resynchronization dynamics of the vertebrate segmentation clock2019
- Author(s)
  Uriu K.
- Organizer
  日本数理生物学会2019年度年会
- Data Source
  KAKENHI-PUBLICLY-19H04772
[Presentation] Period after effectの数理モデリング2019
- Author(s)
  瓜生耕一郎, 程肇
- Organizer
  第26回日本時間生物学会学術大会
- Data Source
  KAKENHI-PUBLICLY-19H04955
[Presentation] Resynchronization of the zebrafish segmentation clock in Delta-Notch mutants2019
- Author(s)
  Uriu K., Liao B-K., Morelli L.G., Oates A.C
- Organizer
  第52回日本発生生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04772
[Presentation] Synchrony recovery of the zebrafish segmentation clock2018
- Author(s)
  Koichiro Uriu
- Organizer
  International young scientists workshop on neural development & stem cells 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Presentation] Interplay between cell movement and intercellular signaling in development2018
- Author(s)
  瓜生耕一郎
- Organizer
  The JSDB-GfE young scientist exchange meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Presentation] Dead zone formation by negative feedback loops in the circadian clocks2018
- Author(s)
  瓜生耕一郎
- Organizer
  2018 Annual Meeting of the Society for Mathematical Biology & the Japanese Society for Mathematical Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Presentation] Dead zone formation by saturated reactions in circadian clocks2018
- Author(s)
  瓜生耕一郎
- Organizer
  第25回日本時間生物学会学術大会
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Presentation] Resynchronization dynamics of the zebrafish segmentation clock2018
- Author(s)
  瓜生耕一郎
- Organizer
  第70回日本細胞生物学会第51回日本発生生物学会合同大会
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Presentation] Physical modeling of oscillator resynchronization after perturbation of Delta-Notch signaling in zebrafish presomitic mesoderm2017
- Author(s)
  Koichiro Uriu
- Organizer
  第50回日本発生生物学会年会
- Data Source
  KAKENHI-PUBLICLY-17H05762
[Presentation] 細胞移動が分節時計の同期に与える影響をイメージングデータと数理モデルで明らかにする2016
- Author(s)
  瓜生耕一郎
- Organizer
  日本発生生物学会秋季シンポジウム2016
- Place of Presentation
  静岡県三島市三島市民文化会館
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Quantification and mathematical modeling of the effect of cellular movement on oscillator synchronization in vertebrate somitogenesis2015
- Author(s)
  Koichiro Uriu, Bhavna Rajasekaran, Luis G. Morelli, Andrew C. Oates
- Organizer
  The 26th CDB meeting
- Place of Presentation
  理化学研究所多細胞システム形成研究センター、兵庫
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Relative cellular motion in vertebrate somitogenesis2015
- Author(s)
  Koichiro Uriu
- Organizer
  日本発生生物学会年会
- Place of Presentation
  つくば国際会議場、茨城
- Year and Date
  2015-06-02
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Modeling cellular motion in vertebrate somitogenesis based on embryonic imaging data2015
- Author(s)
  Koichiro Uriu
- Organizer
  2015年日本数理生物学会年会/日中韓数理生物学コロキウム合同大会
- Place of Presentation
  同志社大学、京都
- Year and Date
  2015-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Quantification of relative cellular movement and mathematical modeling in vertebrate somitogenesis2015
- Author(s)
  Koichiro Uriu
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、兵庫
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Collective cell movement promotes synchronization of coupled genetic oscillators
- Author(s)
  Koichiro Uriu
- Organizer
  The Joint Meeting of the Japanese Society for Mathematical Biology and the Society for Mathematical Biology 2014
- Place of Presentation
  Osaka, Japan
- Year and Date
  2014-07-28 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Collective cell movement promotes synchronization of coupled genetic oscillators
- Author(s)
  Koichiro Uriu
- Organizer
  The 9th European Conference on Mathematical and Theoretical Biology
- Place of Presentation
  Gothenburg, Sweden
- Year and Date
  2014-06-15 – 2014-06-19
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Synchronization of coupled genetic oscillators promoted by collective cell movement
- Author(s)
  Koichiro Uriu
- Organizer
  CDB Symposium 2015 Time in Development
- Place of Presentation
  Kobe, Japan
- Year and Date
  2015-03-23 – 2015-03-25
- Data Source
  KAKENHI-PROJECT-26840085
[Presentation] Collective cell movement promotes synchronization of the segmentation clock
- Author(s)
  瓜生耕一郎
- Organizer
  第47回日本発生生物学会年会
- Place of Presentation
  愛知
- Year and Date
  2014-05-27 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26840085

1. 丹羽康貴 (40590071)

# of Collaborated Projects: 1 results

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2. 坂本雅行 (00777865)

# of Collaborated Projects: 1 results

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3. 宮脇寛行 (40785979)

# of Collaborated Projects: 1 results

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4. 阪東勇輝 (70826809)

# of Collaborated Projects: 1 results

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5. 真仁田聡 (80584135)

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6. 程肇 (00242115)

# of Collaborated Projects: 1 results

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7. 高田慎治

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Uriu Koichiro 瓜生 耕一郎

Research Projects

Research Products

Co-Researchers

眠気の生成・解消機構の解明のための総括研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞状態遷移と神経回路遷移をつなぐ数理モデル: 眠気の生成・解消機構の理論Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Period1誘導化合物の位相前進作用の解明とそれを用いた内的脱同調モデルの構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of gene expression rhythms in a population of mobile cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synchronization of developmental clock under tissue deformationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Phase response theory of the circadian clocks and its experimental validationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Spatiotemporal dynamics of developmental clocks: mathematical modeling of resynchronization process of the segmentation clockPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mathematical modeling of collective cell movementPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Orchestration of tissue shape changes and gene expression patterns in development.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell size homeostasis under the circadian regulation of cell division in cyanobacteria.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] From local resynchronization to global pattern recovery in the zebrafish segmentation clock2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complementary phase responses via functional differentiation of dual negative feedback loops2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synchronization dynamics of mobile oscillators in the presence of coupling delays2019

Author(s)

Journal Title

Uriu Koichiro 瓜生耕一郎