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Namba Takayuki  難波 貴之

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Takayuki Namba  難波 貴之

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Researcher Number 90726499
Affiliation (Current) 2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院 内科, 助教
Affiliation (based on the past Project Information) *help 2020: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院 内科, 講師
2019 – 2020: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院 内科, 助教
2018: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院 内科, 講師
2017: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院 内科, 助教
Review Section/Research Field
Principal Investigator
Cardiovascular medicine
Keywords
Principal Investigator
内皮機能 / 活性酸素種 / 血管内皮障害 / 脂肪肝 / 二型糖尿病 / プロスタノイド / 酸化ストレス / 肥満 / 血管収縮因子 / 肺高血圧 … More / 血管内皮細胞 / インスリン抵抗性 / 血管内皮機能 / 一酸化窒素 / ERK2 / 2型糖尿病 / メタボリックシンドローム / インスリン Less
  • Research Projects

    (1 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (5 People)
  •  Vascular/organ association via ERK2 in insulin resistancePrincipal Investigator

    • Principal Investigator
      Takayuki Namba
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      National Defense Medical College

All 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study2020

    • Author(s)
      Toya Takumi、Ito Kei、Kagami Kazuki、Osaki Ayumu、Sato Atsushi、Kimura Toyokazu、Horii Shunpei、Yasuda Risako、Namba Takayuki、Ido Yasuo、Nagatomo Yuji、Hayashi Katsumi、Masaki Nobuyuki、Yada Hirotaka、Adachi Takeshi
    • Journal Title

      IJC Heart & Vasculature

      Volume: 26 Pages: 100437-100437

    • DOI

      10.1016/j.ijcha.2019.100437

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
  • [Journal Article] Computed tomography-measured pulmonary artery to aorta ratio and EUTOS score for detecting dasatinib-induced pulmonary arterial hypertension2019

    • Author(s)
      Toya Takumi、Nagatomo Yuji、Kagami Kazuki、Yukino Midori、Yasuda Risako、Namba Takayuki、Ido Yasuo、Kobayashi Shinichi、Masaki Nobuyuki、Yada Hirotaka、Kimura Fumihiko、Adachi Takeshi
    • Journal Title

      The International Journal of Cardiovascular Imaging

      Volume: 35 Issue: 8 Pages: 1435-1442

    • DOI

      10.1007/s10554-019-01548-2

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
  • [Journal Article] Arterial Stiffness Assessed by Cardio-Ankle Vascular Index2019

    • Author(s)
      Namba Takayuki、Masaki Nobuyuki、Takase Bonpei、Adachi Takeshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 15 Pages: 3664-3664

    • DOI

      10.3390/ijms20153664

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815, KAKENHI-PROJECT-17K09565
  • [Journal Article] A Rare Case of Rush Progression of Purulent Pericarditis by <i>Escherichia coli</i> in a Patient with Malignant Lymphoma2018

    • Author(s)
      Horii Shunpei、Yada Hirotaka、Ito Kei、Osaki Ayumu、Sato Atsushi、Kimura Toyokazu、Yasuda Risako、Toya Takumi、Namba Takayuki、Masaki Nobuyuki、Adachi Takeshi
    • Journal Title

      Int. Heart J.

      Volume: 59 Issue: 3 Pages: 655-659

    • DOI

      10.1536/ihj.17-238

    • NAID

      130007378304

    • ISSN
      1349-2365, 1349-3299
    • Year and Date
      2018-05-31
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] 肥満・糖尿病における血管内皮ERK2/TP Receptor経路を介した血管内皮障害2020

    • Author(s)
      2)足立健 佐藤篤志、佐藤泰司、大崎歩、鏡和樹、難波貴之
    • Organizer
      2020年 第49回日本心脈管作動性物質 久留米
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] High Fat High Sucrose Diet Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide Production by ERK2/TP Receptor Pathway.2019

    • Author(s)
      Atsushi Sato, Kei Ito, Kazuki Kagami, Ayumu Osaki, Takayuki Namba, Takeshi Adachi;
    • Organizer
      3rd Japanese Circulation Society BCVR 2019, Tokyo YIA 優秀賞
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Association of Hemodynamic Measurements Before Discharge with Lung Congestion.2019

    • Author(s)
      Takayuki Namba, Toyokazu Kimura, Risako Yasuda, Takumi Toya, Yuji Nagatomo Nobuyuki Masaki, Hirotaka Yada, Takeshi Adachi
    • Organizer
      第22回日本心不全学会 2019年 10月
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] 高脂肪高ショ糖食下における血管内皮ERK2/Thromboxane Receptor Pathwayがスーパーオキサイド産生を介して与える血管内皮機能、インスリン抵抗性および脂肪肝への影響の検討2019

    • Author(s)
      佐藤篤志、佐藤泰司、遠藤昌吾、木村豊和、大崎歩、堀井俊平、伊藤桂、鏡和樹、難波貴之 足立健
    • Organizer
      2019年第19回日本NO学会 YIA 優秀賞
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Endothelial ERK2/Thromboxane Receptor Pathway Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide with High Fat High Sucrose Diet.2019

    • Author(s)
      Atsushi Sato, Yasushi Satoh, Shogo Endo, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Kazuki Kagami Takayuki Namba, Takeshi Adachi;
    • Organizer
      European Society of Cardiology 2019 Paris
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia by catecholamine injection and hypertrophy with Angiotensin II.2018

    • Author(s)
      Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
    • Organizer
      91th American Heart Association, Scientific Session 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Angiotensin II loading in SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia2018

    • Author(s)
      Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
    • Organizer
      日本不整脈学会総会YIA 最優秀賞
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] SERCA2 C674S heterozygote kock-in mice with angioteinsion II infusion leads to QT prologation and lethal ventricular arrhythmia due to impaired sarcoplasmic reticulum Ca2+ handling2018

    • Author(s)
      Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
    • Organizer
      European Society of Cardiology 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] High Fat/ High Sucrose Diet Did Not Induce Endothelial Dysfunction but Impaired the Reduction of Vascular Tone with Adipose Tissue in Aortic Ring from Mice2018

    • Author(s)
      Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Kei Ito, Takumi Toya, Ysauo Ido, Nobuyuki Masaki, Takayuki Namba, Takeshi Adachi
    • Organizer
      91th American Heart Association, Scientific Session 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Ectopic Fat Deposition with Organ Damages in Adipose Specific Extracellular Signal-Regulated Kinase 2 Deficient Mice with High Fat Diet2018

    • Author(s)
      Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Tohya, Yasuo Ido, Nobuyuki Masaki, Takayuki Namba, Takeshi Adachi
    • Organizer
      82nd Japanese Circulation Society 2018
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Histological Validation of Cardiac Magnetic Resonance T1 Mapping as an Indicator of Interstitial Myocardial Fibrosis in Non-Ischemic Cardiomyopathy Patients2018

    • Author(s)
      Takumi Toya, Nobuyuki Masaki, Katsumi Hayashi, Atsushi Sato, Ayumu Osaki, Kei Ito, Shunpei Horii, Risako Yasuda, Yasuo Ido, Takayuki Namba, Yuji Nagatomo, Hirotaka Yada, Takeshi Adachi
    • Organizer
      82nd Japanese Circulation Society 2018
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Association between Total Cholesterol and Ratio of Direct to Total Bilirubin in Serum2018

    • Author(s)
      Masataka Mine, Nobuyuki Masaki, Tetsuya Hisada, Risako Yasuda, Takayuki Namba, Hirotaka Yada, Kenichi Hashimoto, Bonpei Takase, Takeshi Adachi
    • Organizer
      82nd Japanese Circulation Society 2018
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Adipose Extracellular Signal-Regulated Kinase 2 Protect From Ectopic Fat Depositions and Endothelial Dysfunction in Obesity2018

    • Author(s)
      Ayumu Osaki, Yasushi Satoh, Shogo Endo, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Toya, Ysauo Ido, Takayuki Namba, Takeshi Adachi
    • Organizer
      91th American Heart Association, Scientific Session 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Adipose Extracellular Signal-Regulated Kinase 2 Deficiency Impaired Endothelial Function and the Modulation of Vascular Tone with Adipose Tissue2018

    • Author(s)
      Ayumu Osaki, Yasushi Satoh, Shogo Endo, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Toya, Ysauo Ido, Takayuki Namba, Takeshi Adachi
    • Organizer
      91th American Heart Association, Scientific Session 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Induced Hypertension and Endothelial Dysfunction and Insulin Resistance in Obese2018

    • Author(s)
      Atsushi Sato, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takumi Tohya, Nobuyuki Masaki, Takayuki Namba Takeshi Adachi.
    • Organizer
      82nd Japanese Circulation Society 2018
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Adipose Specific Extracellular Signal-Regulated Kinase 2 suppresses Ectopic Fat and limit Organ Damage in Obese2018

    • Author(s)
      Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Kei Ito, Takumi Toya, Nobuyuki Masaki ,Takayuki Namba, Takeshi Adachi
    • Organizer
      日本循環器学会総会 (JCS) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Increased Basal eNOS Activity in Freshly Isolated Endothelial Cells from Patients with Cardiovascular Disease2018

    • Author(s)
      Nobuyuki Masaki, Youhei Yamashita, Toshiyuki Yamada, Yasuo Ido, Risako Yasuda, Takumi Tohya, Takayuki Nanba, Yuji Nagatomo, Hirotaka Yada, Kenichi Hashimoto, Bonpei Takase, Takeshi Adachi
    • Organizer
      82nd Japanese Circulation Society 2018
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 induced Hypertension and Endothelial Dysfunction and Insulin Resistance in Obese2018

    • Author(s)
      Atsushi Sato, Yasushi Satoh, Shogo Endo, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takayuki Namba, Takesshi Adachi
    • Organizer
      日本循環器学会総会 (JCS) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] The mechanism of lean body in SOD1 deficient mice with High Fat High Sucrose Diet: The role of activated AMP-Activated Protein Kinase with Oxidative Stress.2017

    • Author(s)
      Atsushi Sato, Yasunaga Shiraishi, Ayumu Osaki, Toyokazu Kimura, Takumi Toya, Risako Yasuda, Takayuki Namba, Hirotaka Yada, Nobuyuki Masaki, Takeshi Adachi
    • Organizer
      AHA Scientific Session 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • [Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Increases Blood Pressure and Induced Endothelial Dysfunction and Insulin Resistance in Mice with High Fat High Sucrose Diet2017

    • Author(s)
      Atsushi Sato, Yasushi Satoh, Endo XXXX, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takayuki Namba, Takeshi Adachi
    • Organizer
      AHA Scientific Session 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09596
  • 1.  眞崎 暢之 (00364795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  佐藤 泰司 (10505267)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 3.  足立 健 (50231931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 23 results
  • 4.  東谷 卓美 (60781515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  真崎 暢之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 15 results

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