Namba Takayuki 難波貴之

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Takayuki Namba 難波貴之

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Researcher Number	90726499
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院内科, 助教
Affiliation (based on the past Project Information) *help	2020: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院内科, 講師 2019 – 2020: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院内科, 助教 2018: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院内科, 講師 2017: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 病院内科, 助教
Review Section/Research Field	Principal Investigator Cardiovascular medicine
Keywords	Principal Investigator 内皮機能 / 活性酸素種 / 血管内皮障害 / 脂肪肝 / 二型糖尿病 / プロスタノイド / 酸化ストレス / 肥満 / 血管収縮因子 / 肺高血圧 … More / 血管内皮細胞 / インスリン抵抗性 / 血管内皮機能 / 一酸化窒素 / ERK2 / 2型糖尿病 / メタボリックシンドローム / インスリン Less

Vascular/organ association via ERK2 in insulin resistancePrincipal Investigator
- Principal Investigator
  
  Takayuki Namba
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Defense Medical College

All 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study2020
- Author(s)
  Toya Takumi、Ito Kei、Kagami Kazuki、Osaki Ayumu、Sato Atsushi、Kimura Toyokazu、Horii Shunpei、Yasuda Risako、Namba Takayuki、Ido Yasuo、Nagatomo Yuji、Hayashi Katsumi、Masaki Nobuyuki、Yada Hirotaka、Adachi Takeshi
- Journal Title
  
  IJC Heart & Vasculature
  
  Volume: 26 Pages: 100437-100437
- DOI
  10.1016/j.ijcha.2019.100437
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
[Journal Article] Computed tomography-measured pulmonary artery to aorta ratio and EUTOS score for detecting dasatinib-induced pulmonary arterial hypertension2019
- Author(s)
  Toya Takumi、Nagatomo Yuji、Kagami Kazuki、Yukino Midori、Yasuda Risako、Namba Takayuki、Ido Yasuo、Kobayashi Shinichi、Masaki Nobuyuki、Yada Hirotaka、Kimura Fumihiko、Adachi Takeshi
- Journal Title
  
  The International Journal of Cardiovascular Imaging
  
  Volume: 35 Issue: 8 Pages: 1435-1442
- DOI
  10.1007/s10554-019-01548-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815
[Journal Article] Arterial Stiffness Assessed by Cardio-Ankle Vascular Index2019
- Author(s)
  Namba Takayuki、Masaki Nobuyuki、Takase Bonpei、Adachi Takeshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 15 Pages: 3664-3664
- DOI
  10.3390/ijms20153664
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596, KAKENHI-PROJECT-18H02815, KAKENHI-PROJECT-17K09565
[Journal Article] A Rare Case of Rush Progression of Purulent Pericarditis by <i>Escherichia coli</i> in a Patient with Malignant Lymphoma2018
- Author(s)
  Horii Shunpei、Yada Hirotaka、Ito Kei、Osaki Ayumu、Sato Atsushi、Kimura Toyokazu、Yasuda Risako、Toya Takumi、Namba Takayuki、Masaki Nobuyuki、Adachi Takeshi
- Journal Title
  
  Int. Heart J.
  
  Volume: 59 Issue: 3 Pages: 655-659
- DOI
  10.1536/ihj.17-238
- NAID
  130007378304
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2018-05-31
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] 肥満・糖尿病における血管内皮ERK2/TP Receptor経路を介した血管内皮障害2020
- Author(s)
  2）足立健　佐藤篤志、佐藤泰司、大崎歩、鏡和樹、難波貴之
- Organizer
  2020年　第49回日本心脈管作動性物質　久留米
- Invited
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] High Fat High Sucrose Diet Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide Production by ERK2/TP Receptor Pathway.2019
- Author(s)
  Atsushi Sato, Kei Ito, Kazuki Kagami, Ayumu Osaki, Takayuki Namba, Takeshi Adachi;
- Organizer
  3rd Japanese Circulation Society BCVR 2019, Tokyo YIA 優秀賞
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Association of Hemodynamic Measurements Before Discharge with Lung Congestion.2019
- Author(s)
  Takayuki Namba, Toyokazu Kimura, Risako Yasuda, Takumi Toya, Yuji Nagatomo Nobuyuki Masaki, Hirotaka Yada, Takeshi Adachi
- Organizer
  第22回日本心不全学会 2019年 10月
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] 高脂肪高ショ糖食下における血管内皮ERK2/Thromboxane Receptor Pathwayがスーパーオキサイド産生を介して与える血管内皮機能、インスリン抵抗性および脂肪肝への影響の検討2019
- Author(s)
  佐藤篤志、佐藤泰司、遠藤昌吾、木村豊和、大崎歩、堀井俊平、伊藤桂、鏡和樹、難波貴之　足立健
- Organizer
  2019年第１９回日本NO学会　YIA 優秀賞
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial ERK2/Thromboxane Receptor Pathway Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide with High Fat High Sucrose Diet.2019
- Author(s)
  Atsushi Sato, Yasushi Satoh, Shogo Endo, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Kazuki Kagami Takayuki Namba, Takeshi Adachi;
- Organizer
  European Society of Cardiology 2019 Paris
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia by catecholamine injection and hypertrophy with Angiotensin II.2018
- Author(s)
  Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Angiotensin II loading in SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia2018
- Author(s)
  Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
- Organizer
  日本不整脈学会総会YIA 最優秀賞
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] SERCA2 C674S heterozygote kock-in mice with angioteinsion II infusion leads to QT prologation and lethal ventricular arrhythmia due to impaired sarcoplasmic reticulum Ca2+ handling2018
- Author(s)
  Kei Ito, Hirotaka Yada, Shunpei Horii, Takumi Toya, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Atsushi Sato, Risako Yasuda, Takayuki Namba, Yuji Nagatomo, Nobuyuki Masaki, Yasuo Ido, Bonpei Takase, Takeshi Adachi
- Organizer
  European Society of Cardiology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] High Fat/ High Sucrose Diet Did Not Induce Endothelial Dysfunction but Impaired the Reduction of Vascular Tone with Adipose Tissue in Aortic Ring from Mice2018
- Author(s)
  Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Kei Ito, Takumi Toya, Ysauo Ido, Nobuyuki Masaki, Takayuki Namba, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Ectopic Fat Deposition with Organ Damages in Adipose Specific Extracellular Signal-Regulated Kinase 2 Deficient Mice with High Fat Diet2018
- Author(s)
  Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Tohya, Yasuo Ido, Nobuyuki Masaki, Takayuki Namba, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Histological Validation of Cardiac Magnetic Resonance T1 Mapping as an Indicator of Interstitial Myocardial Fibrosis in Non-Ischemic Cardiomyopathy Patients2018
- Author(s)
  Takumi Toya, Nobuyuki Masaki, Katsumi Hayashi, Atsushi Sato, Ayumu Osaki, Kei Ito, Shunpei Horii, Risako Yasuda, Yasuo Ido, Takayuki Namba, Yuji Nagatomo, Hirotaka Yada, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Association between Total Cholesterol and Ratio of Direct to Total Bilirubin in Serum2018
- Author(s)
  Masataka Mine, Nobuyuki Masaki, Tetsuya Hisada, Risako Yasuda, Takayuki Namba, Hirotaka Yada, Kenichi Hashimoto, Bonpei Takase, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Adipose Extracellular Signal-Regulated Kinase 2 Protect From Ectopic Fat Depositions and Endothelial Dysfunction in Obesity2018
- Author(s)
  Ayumu Osaki, Yasushi Satoh, Shogo Endo, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Toya, Ysauo Ido, Takayuki Namba, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Adipose Extracellular Signal-Regulated Kinase 2 Deficiency Impaired Endothelial Function and the Modulation of Vascular Tone with Adipose Tissue2018
- Author(s)
  Ayumu Osaki, Yasushi Satoh, Shogo Endo, Atsushi Sato, Toyokazu Kimura, Kei Ito, Takumi Toya, Ysauo Ido, Takayuki Namba, Takeshi Adachi
- Organizer
  91th American Heart Association, Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Induced Hypertension and Endothelial Dysfunction and Insulin Resistance in Obese2018
- Author(s)
  Atsushi Sato, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takumi Tohya, Nobuyuki Masaki, Takayuki Namba Takeshi Adachi.
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Adipose Specific Extracellular Signal-Regulated Kinase 2 suppresses Ectopic Fat and limit Organ Damage in Obese2018
- Author(s)
  Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Kei Ito, Takumi Toya, Nobuyuki Masaki ,Takayuki Namba, Takeshi Adachi
- Organizer
  日本循環器学会総会 (JCS) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Increased Basal eNOS Activity in Freshly Isolated Endothelial Cells from Patients with Cardiovascular Disease2018
- Author(s)
  Nobuyuki Masaki, Youhei Yamashita, Toshiyuki Yamada, Yasuo Ido, Risako Yasuda, Takumi Tohya, Takayuki Nanba, Yuji Nagatomo, Hirotaka Yada, Kenichi Hashimoto, Bonpei Takase, Takeshi Adachi
- Organizer
  82nd Japanese Circulation Society 2018
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 induced Hypertension and Endothelial Dysfunction and Insulin Resistance in Obese2018
- Author(s)
  Atsushi Sato, Yasushi Satoh, Shogo Endo, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takayuki Namba, Takesshi Adachi
- Organizer
  日本循環器学会総会 (JCS) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] The mechanism of lean body in SOD1 deficient mice with High Fat High Sucrose Diet: The role of activated AMP-Activated Protein Kinase with Oxidative Stress.2017
- Author(s)
  Atsushi Sato, Yasunaga Shiraishi, Ayumu Osaki, Toyokazu Kimura, Takumi Toya, Risako Yasuda, Takayuki Namba, Hirotaka Yada, Nobuyuki Masaki, Takeshi Adachi
- Organizer
  AHA Scientific Session 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596
[Presentation] Endothelial Extracellular Signal-Regulated Kinase 2 Increases Blood Pressure and Induced Endothelial Dysfunction and Insulin Resistance in Mice with High Fat High Sucrose Diet2017
- Author(s)
  Atsushi Sato, Yasushi Satoh, Endo XXXX, Toyokazu Kimura, Ayumu Osaki, Shunpei Horii, Kei Ito, Takayuki Namba, Takeshi Adachi
- Organizer
  AHA Scientific Session 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09596

1. 眞崎暢之 (00364795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 佐藤泰司 (10505267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
3. 足立健 (50231931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
4. 東谷卓美 (60781515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 真崎暢之

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results

Namba Takayuki 難波 貴之

Takayuki Namba 難波 貴之

Research Projects

Research Products

Co-Researchers

Vascular/organ association via ERK2 in insulin resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computed tomography-measured pulmonary artery to aorta ratio and EUTOS score for detecting dasatinib-induced pulmonary arterial hypertension2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arterial Stiffness Assessed by Cardio-Ankle Vascular Index2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Rare Case of Rush Progression of Purulent Pericarditis by <i>Escherichia coli</i> in a Patient with Malignant Lymphoma2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Presentation] 肥満・糖尿病における血管内皮ERK2/TP Receptor経路を介した血管内皮障害2020

Author(s)

Organizer

Data Source

[Presentation] High Fat High Sucrose Diet Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide Production by ERK2/TP Receptor Pathway.2019

Author(s)

Organizer

Data Source

[Presentation] Association of Hemodynamic Measurements Before Discharge with Lung Congestion.2019

Author(s)

Organizer

Data Source

[Presentation] 高脂肪高ショ糖食下における血管内皮ERK2/Thromboxane Receptor Pathwayがスーパーオキサイド産生を介して与える血管内皮機能、インスリン抵抗性および脂肪肝への影響の検討2019

Author(s)

Organizer

Data Source

[Presentation] Endothelial ERK2/Thromboxane Receptor Pathway Induced Endothelial Dysfunction, Insulin Resistance and Steatohepatosis through Superoxide with High Fat High Sucrose Diet.2019

Author(s)

Organizer

Data Source

[Presentation] SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia by catecholamine injection and hypertrophy with Angiotensin II.2018

Author(s)

Organizer

Data Source

[Presentation] Angiotensin II loading in SERCA2 C674S heterozygote knock-in mice leads to QT prolongation and lethal ventricular arrhythmia2018

Author(s)

Organizer

Data Source

[Presentation] SERCA2 C674S heterozygote kock-in mice with angioteinsion II infusion leads to QT prologation and lethal ventricular arrhythmia due to impaired sarcoplasmic reticulum Ca2+ handling2018

Author(s)

Organizer

Data Source

[Presentation] High Fat/ High Sucrose Diet Did Not Induce Endothelial Dysfunction but Impaired the Reduction of Vascular Tone with Adipose Tissue in Aortic Ring from Mice2018

Author(s)

Organizer

Data Source

[Presentation] Ectopic Fat Deposition with Organ Damages in Adipose Specific Extracellular Signal-Regulated Kinase 2 Deficient Mice with High Fat Diet2018

Author(s)

Organizer

Data Source

[Presentation] Histological Validation of Cardiac Magnetic Resonance T1 Mapping as an Indicator of Interstitial Myocardial Fibrosis in Non-Ischemic Cardiomyopathy Patients2018

Author(s)

Organizer

Data Source

[Presentation] Association between Total Cholesterol and Ratio of Direct to Total Bilirubin in Serum2018

Namba Takayuki 難波貴之

Takayuki Namba 難波貴之