Yamazaki Tomohiro 山崎智弘

… Alternative Names

Tomohiro Yamazaki 山崎智弘

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Researcher Number	90732280
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院生命機能研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院生命機能研究科, 特任講師(常勤) 2019 – 2021: 大阪大学, 生命機能研究科, 特任講師 2018 – 2019: 北海道大学, 遺伝子病制御研究所, 講師 2014 – 2017: 北海道大学, 遺伝子病制御研究所, 助教
Review Section/Research Field	Principal Investigator Molecular biology / Biological Sciences / Basic Section 43010:Molecular biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Transformative Research Areas, Section (III)
Keywords	Principal Investigator NEAT1 / パラスペックル / 相分離 / lncRNA / ミセル化 / ブロック共重合体 / RNA / RNA結合タンパク質 / 核内構造体 / 長鎖ノンコーディングRNA … More / 非膜性構造体 / 非膜オルガネラ / architectural RNA / 構成的アプローチ / 細胞内相分離 / ゲノム制御 / arcRNA / 長鎖ノンコーディングRNA（lncRNA） / CRISPR/Cas9 / クロマチン / 遺伝子発現制御 / SARS-CoV-2 / 非膜性オルガネラ / 核内ストレス体 / RNAウイルス / ソフトマター物理 / ハイコンテントスクリーニング / 天然変性タンパク質 / タンパク質 / MCPタンパク質ライブラリー / 遺伝子発現 / 高次ゲノム構造 / 癌 / ソフトマター物理学 / ミセル / ヒト一倍体細胞株 / Low complexity domain / 相転移 / Long noncoding RNA / ヒト一倍体細胞 / 天然変性領域 / ノンコーディングRNA / HAP1 / RNA-seq / RNAシークエンス / RNA抽出 / Gem / 神経変性疾患 / プリオン様ドメイン Less

細胞内相分離を誘導するタンパク質の大規模探索と誘導機構の解明Principal Investigator
- Principal Investigator
  
  山崎智弘
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
Regulatory mechanism of gene expression by membraneless organelles formed through micellizationPrincipal Investigator
- Principal Investigator
  
  山崎智弘
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka University
Mechanisms to define the structure, properties, and function of RNP biomolecular condensatesPrincipal Investigator
- Principal Investigator
  
  山崎智弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Osaka University
Chromatin regulation by RNA-induced phase separationPrincipal Investigator
- Principal Investigator
  
  山崎智弘
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Mechanisms of the principles to construct and design phase-separated RNP nanostructuresPrincipal Investigator
- Principal Investigator
  
  Yamazaki Tomohiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Osaka University
  Hokkaido University
Genome regulation by phase-separated nuclear RNP bodiesPrincipal Investigator
- Principal Investigator
  
  山崎智弘
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Mechanisms for phase separation of RNA-induced nuclear bodiesPrincipal Investigator
- Principal Investigator
  
  Yamazaki Tomohiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Hokkaido University
Identification of the RNA elements that determine semi-extractability of RNAsPrincipal Investigator
- Principal Investigator
  
  Tomohiro Yamazaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Hokkaido University
プリオン様ドメインとRNAを介した核内構造体構築機構の解明Principal Investigator
- Principal Investigator
  
  山崎智弘
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Molecular biology
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book

[Book] 「非ドメイン型arcRNAによる非膜オルガネラ形成」Meidcal Science Digest2023
- Author(s)
  山崎智弘、廣瀬哲郎
- Total Pages
  66
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23K18112
[Book] 「非ドメイン型arcRAによる非膜オルガネラ形成」Medical Science Digest2023
- Author(s)
  山崎智弘、廣瀬哲郎
- Total Pages
  66
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23K23809
[Book] セントラルドグマの新常識2022
- Author(s)
  山崎智弘、山本哲也、廣瀬哲郎（担当、分担執筆、範囲:RNAの新常識6:細胞内構造体の骨格として働くRNA）
- Total Pages
  264
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Book] フロントランナー直伝相分離解析プロトコール2022
- Author(s)
  山崎智弘、廣瀬哲郎（担当、分担執筆、範囲:レビュー編4:細胞内相分離におけるRNAの役割）
- Total Pages
  247
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Book] フロントランナー直伝　相分離解析プロトコール2022
- Author(s)
  山崎智弘、廣瀬哲郎（担当、分担執筆、範囲：レビュー編4：細胞内相分離におけるRNAの役割）
- Total Pages
  247
- Publisher
  羊土社
- ISBN
  9784758122597
- Data Source
  KAKENHI-PROJECT-23K23809
[Book] セントラルドグマの新常識2022
- Author(s)
  山崎智弘、山本哲也、廣瀬哲郎（担当、分担執筆、範囲：RNAの新常識6：細胞内構造体の骨格として働くRNA）
- Total Pages
  264
- Publisher
  羊土社
- ISBN
  9784758104043
- Data Source
  KAKENHI-PROJECT-23K23809
[Book] 月刊　細胞2021
- Author(s)
  山本哲也、山崎智弘、二宮賢介、廣瀬哲郎（担当：分担執筆、範囲：RNA生物学とソフトマター物理学の融合による核内構造体の研究）
- Total Pages
  76
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-19K06479
[Book] 相分離　メカニズムと疾患2021
- Author(s)
  山崎智弘、廣瀬哲郎（担当：分担執筆、範囲：I. 核内の非膜オルガネラ 4. パラスペックル）
- Total Pages
  221
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Book] 相分離　メカニズムと疾患2021
- Author(s)
  山崎智弘、廣瀬哲郎（担当：分担執筆、範囲：I. 核内の非膜オルガネラ 4. パラスペックル）
- Total Pages
  221
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19K06479
[Book] 月刊　細胞2021
- Author(s)
  山本哲也、山崎智弘、二宮賢介、廣瀬哲郎（担当：分担執筆、範囲：RNA生物学とソフトマター物理学の融合による核内構造体の研究）
- Total Pages
  76
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Book] 相分離生物学の全貌2020
- Author(s)
  山崎智弘、廣瀬哲郎(担当:分担執筆, 範囲:核内の相分離)
- Total Pages
  402
- Publisher
  東京化学同人
- ISBN
  9784807913466
- Data Source
  KAKENHI-PROJECT-19K06479
[Book] 相分離生物学の全貌2020
- Author(s)
  山崎智弘, 廣瀬哲郎(担当:分担執筆, 範囲:核内の相分離)
- Total Pages
  402
- Publisher
  東京化学同人
- ISBN
  9784807913466
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Book] 医学のあゆみ「マイクロRNA研究の進歩」（このうち「lncRNAの機能と関連疾患」を執筆）2019
- Author(s)
  山崎智弘、廣瀬哲郎
- Total Pages
  120
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Book] 実験医学2019年6月号「細胞内の相分離」（ノンコーディングRNAにより誘導される核内構造体形成機構）2019
- Author(s)
  加藤　昌人、廣瀬　哲郎（高桑央、山崎智弘、廣瀬哲郎）
- Total Pages
  145
- Publisher
  羊土社
- ISBN
  9784758125208
- Data Source
  KAKENHI-PROJECT-19K06479
[Book] 実験医学「細胞内の相分離ータンパク質や核酸分子を整理し、反応の場を作り、生命を駆動するー」2019
- Author(s)
  加藤昌人、田中肇、加藤昌人、吉澤拓也、杉本亜砂子、高桑央，山崎智弘，廣瀬哲郎、野澤竜介、鈴木洋、小池佑佳，石原智彦，小野寺理
- Total Pages
  145
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Book] マイクロRNA研究の進歩（lncRNAの機能と関連疾患）2019
- Author(s)
  落合孝広、山本雄介（山崎智弘、廣瀬哲郎）
- Total Pages
  120
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19K06479
[Book] Applied RNA Bioscience2018
- Author(s)
  Seiji Masuda, Shingo Izawa, Sae Kato, Kei Kitahara, Takahiro Yamauchi, Naofumi Ito, Yuji Morita, Atsushi Ogawa, Kei Endo, Naoyuki Kataoka, Intisar Fouad Ali Mursi, Takayoshi Imai, Tomohiro Yamazaki, Eleonora Leucci, Yoshiya Ikawa, Jennifer Chu, Songling Bai, Yuhya Wakasa
- Total Pages
  286
- Publisher
  Springer
- ISBN
  9789811083716
- Data Source
  KAKENHI-PROJECT-17K15058
[Book] Applied RNA Bioscience, Chapter 11, Long Noncoding RNAs and Their Applications:Focus on Architectural RNA (arcRNA), a Class of lncRNA2018
- Author(s)
  Tomohiro Yamazaki
- Total Pages
  286
- Publisher
  Springer
- ISBN
  9789811083716
- Data Source
  KAKENHI-PROJECT-17K15058
[Book] ノンコーディングRNAテキストブック2015
- Author(s)
  山崎智弘、廣瀬哲郎
- Total Pages
  251
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K18474
[Journal Article] Terminal regions of UAP56 and URH49 are required for their distinct complex formation functioning to an essential role in mRNA processing and export.2024
- Author(s)
  K-I. Fujita, T. Yamazaki, A. Mayeda, S. Masuda
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 703 Pages: 149682-149682
- DOI
  10.1016/j.bbrc.2024.149682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K19078, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-23K23809
[Journal Article] Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes.2024
- Author(s)
  K-I. Fujita, M. Ito, M. Irie, K. Harada, N. Fujiwara, Y. Ikeda, H. Yoshioka, T. Yamazaki, M. Kojima, B. Mikami, A. Mayeda, S. Masuda
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 455-455
- DOI
  10.1038/s41467-023-44217-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K19078, KAKENHI-PROJECT-21K15538, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-23K23809
[Journal Article] Satellite RNAs: emerging players in subnuclear architecture and gene regulation2023
- Author(s)
  Ninomiya Kensuke、Yamazaki Tomohiro、Hirose Tetsuro
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 18
- DOI
  10.15252/embj.2023114331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06083, KAKENHI-PROJECT-22K19293, KAKENHI-PLANNED-21H05276, KAKENHI-PUBLICLY-23H04258
[Journal Article] Shell protein composition specified by the lncRNA NEAT1 domains dictates the formation of paraspeckles as distinct membraneless organelles2023
- Author(s)
  Takakuwa Hiro、Yamazaki Tomohiro、Souquere Sylvie、Adachi Shungo、Yoshino Hyura、Fujiwara Naoko、Yamamoto Tetsuya、Natsume Tohru、Nakagawa Shinichi、Pierron Gerard、Hirose Tetsuro
- Journal Title
  
  Nature Cell Biology
  
  Volume: 25 Issue: 11 Pages: 1664-1675
- DOI
  10.1038/s41556-023-01254-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18112, KAKENHI-PROJECT-22K19293, KAKENHI-ORGANIZER-21H05273, KAKENHI-PLANNED-21H05274, KAKENHI-PLANNED-21H05276, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-23K23809
[Journal Article] 4.5SH RNA counteracts deleterious exonization of SINE B1 in mice2023
- Author(s)
  Yoshimoto Rei、Nakayama Yuta、Nomura Ikuko、Yamamoto Ikuko、Nakagawa Yumeka、Tanaka Shigeyuki、Kurihara Misuzu、Suzuki Yu、Kobayashi Takehiko、Kozuka-Hata Hiroko、Oyama Masaaki、Mito Mari、Iwasaki Shintaro、Yamazaki Tomohiro、Hirose Tetsuro、Araki Kimi、Nakagawa Shinichi
- Journal Title
  
  Molecular Cell
  
  Volume: 83 Issue: 24 Pages: 4479-4493
- DOI
  10.1016/j.molcel.2023.11.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K24688, KAKENHI-PROJECT-22K05565, KAKENHI-ORGANIZER-21H05273, KAKENHI-PLANNED-21H05274, KAKENHI-PLANNED-21H05276, KAKENHI-PLANNED-21H05280, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-23K23809, KAKENHI-PROJECT-23K26910
[Journal Article] Formation and Function of Phase-Separated Nuclear Bodies Directed by Architectural Noncoding RNA2023
- Author(s)
  Takakuwa Hiro、Yamazaki Tomohiro、Hirose Tetsuro
- Journal Title
  
  Phase Separation in Living Cells (Chapter)
  
  Volume: . Pages: 133-156
- DOI
  10.1007/978-981-99-4886-4_8
- ISBN
  9789819948857, 9789819948864
- Data Source
  KAKENHI-PROJECT-23K18112, KAKENHI-PUBLICLY-23H04258
[Journal Article] Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus2023
- Author(s)
  Yamamoto Tetsuya、Yamazaki Tomohiro、Ninomiya Kensuke、Hirose Tetsuro
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 1129-1129
- DOI
  10.1038/s42003-023-05519-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18112, KAKENHI-PROJECT-22K06083, KAKENHI-PROJECT-21K03479, KAKENHI-PLANNED-21H05276, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-23K23809
[Journal Article] Triblock copolymer micelle model of spherical paraspeckles2022
- Author(s)
  Tetsuya Yamamoto, Tomohiro Yamazaki, and Tetsuro Hirose
- Journal Title
  
  Front. Mol. Biosci.
  
  Volume: 9 Pages: 925058-925058
- DOI
  10.3389/fmolb.2022.925058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K03479, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PUBLICLY-21H00241, KAKENHI-PUBLICLY-21H00253, KAKENHI-PROJECT-23K23809, KAKENHI-PLANNED-20H05934
[Journal Article] Editorial: The why of RNA granules: Form, function, and regulation2022
- Author(s)
  Yamazaki Tomohiro、Audas Timothy E.、Farny Natalie G.
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 9
- DOI
  10.3389/fmolb.2022.1111463
- Data Source
  KAKENHI-PUBLICLY-21H00253, KAKENHI-PROJECT-23K23809
[Journal Article] Statistical Thermodynamics Approach for Intracellular Phase Separation2022
- Author(s)
  Tomohiro Yamazaki
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 2509 Pages: 361-393
- DOI
  10.1007/978-1-0716-2380-0_22
- ISBN
  9781071623794, 9781071623800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K03479, KAKENHI-PLANNED-20H05934, KAKENHI-PUBLICLY-21H00241, KAKENHI-PUBLICLY-21H00253, KAKENHI-PROJECT-23K23809
[Journal Article] A guide to membraneless organelles and their various roles in gene regulation2022
- Author(s)
  Hirose Tetsuro、Ninomiya Kensuke、Nakagawa Shinichi、Yamazaki Tomohiro
- Journal Title
  
  Nature Reviews Molecular Cell Biology
  
  Volume: 24 Issue: 4 Pages: 288-304
- DOI
  10.1038/s41580-022-00558-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06083, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PUBLICLY-21H00253, KAKENHI-PROJECT-23K23809, KAKENHI-PROJECT-22K19293
[Journal Article] Micellization: A new principle in the formation of biomolecular condensates2022
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, and Tetsuro Hirose
- Journal Title
  
  Front. Mol. Biosci.
  
  Volume: 9 Pages: 974772-974772
- DOI
  10.3389/fmolb.2022.974772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K03479, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PLANNED-20H05934, KAKENHI-PUBLICLY-21H00241, KAKENHI-PUBLICLY-21H00253, KAKENHI-PROJECT-23K23809
[Journal Article] Remarkable improvement in detection of readthrough downstream-of-gene transcripts by semi-extractable RNA-sequencing2022
- Author(s)
  Iwakiri Junichi、Tanaka Kumiko、Chujo Takeshi、Takakuwa Hiro、Yamazaki Tomohiro、Terai Goro、Asai Kiyoshi、Hirose Tetsuro
- Journal Title
  
  RNA
  
  Volume: 29 Issue: 2 Pages: 170-177
- DOI
  10.1261/rna.079469.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19293, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H00448, KAKENHI-PROJECT-20K12041, KAKENHI-PUBLICLY-21H00253, KAKENHI-PROJECT-23K23809
[Journal Article] RNAが形作る相分離構造体2021
- Author(s)
  山崎智弘、廣瀬哲郎
- Journal Title
  
  生化学
  
  Volume: 93 Pages: 385-390
- NAID
  40022647432
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Journal Article] ArcRNAs and the formation of nuclear bodies.2021
- Author(s)
  Shinichi Nakagawa, Tomohiro Yamazaki, Taro Mannen, Tetsuro Hirose
- Journal Title
  
  Mammalian Genome
  
  Volume: - Issue: 2 Pages: 382-401
- DOI
  10.1007/s00335-021-09881-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06479, KAKENHI-PUBLICLY-21H00253, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PROJECT-20K06493, KAKENHI-PROJECT-21K19246, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06279, KAKENHI-PLANNED-21H05274
[Journal Article] Paraspeckles are constructed as block copolymer micelles.2021
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hyura Yoshino, Sylvie Souquere, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Journal Title
  
  EMBO Journal
  
  Volume: - Issue: 12
- DOI
  10.15252/embj.2020107270
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05250, KAKENHI-PROJECT-19K22374, KAKENHI-PROJECT-19K06479, KAKENHI-PUBLICLY-20H05377, KAKENHI-PUBLICLY-21H00253, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PROJECT-17H03604, KAKENHI-PLANNED-21H05274
[Journal Article] CRISPR-mediated mutagenesis of long noncoding RNAs2021
- Author(s)
  Yamazaki T., Hirose T.
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2254 Pages: 283-303
- DOI
  10.1007/978-1-0716-1158-6_18
- ISBN
  9781071611579, 9781071611586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06479, KAKENHI-PUBLICLY-19H05250, KAKENHI-PUBLICLY-20H05377, KAKENHI-PROJECT-19K22374, KAKENHI-PROJECT-20H00448
[Journal Article] RNAが形作る相分離構造体2021
- Author(s)
  山崎智弘、廣瀬哲郎
- Journal Title
  
  生化学
  
  Volume: 93 Pages: 385-390
- NAID
  40022647432
- Data Source
  KAKENHI-PROJECT-19K06479
[Journal Article] Control of condensates dictates nucleolar architecture.2021
- Author(s)
  Tomohiro Yamazaki, Tetsuro Hirose
- Journal Title
  
  Science
  
  Volume: 373 Issue: 6554 Pages: 486-487
- DOI
  10.1126/science.abj8350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06479, KAKENHI-PUBLICLY-20H05377, KAKENHI-PUBLICLY-21H00253, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448
[Journal Article] Phase separation driven by production of architectural RNA transcripts.2020
- Author(s)
  Tetsuya Yamamoto, Tomohiro Yamazaki, Tetsuro Hirose
- Journal Title
  
  Soft matter
  
  Volume: 16 Issue: 19 Pages: 4692-4698
- DOI
  10.1039/c9sm02458a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06479, KAKENHI-PUBLICLY-19H05250, KAKENHI-PUBLICLY-19H05259, KAKENHI-PUBLICLY-20H05377, KAKENHI-PROJECT-18K03558, KAKENHI-PROJECT-19K22374, KAKENHI-PROJECT-20H00448
[Journal Article] URH49 exports mRNA by remodeling complex formation and mediating the NXF1-dependent pathway.2020
- Author(s)
  Ken-Ichi Fujita, Tomohiro Yamazaki, Kotaro Harada, Shigeto Seno, Hideo Matsuda, Seiji Masuda
- Journal Title
  
  Biochimica et biophysica acta. Gene regulatory mechanisms
  
  Volume: 1863 Pages: 194480-194480
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Journal Article] Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation2020
- Author(s)
  Suzuki Eisuke、Ogawa Namino、Takeda Taka-aki、Nishito Yukina、Tanaka Yu-ki、Fujiwara Takashi、Matsunaga Mayu、Ueda Sachiko、Kubo Naoya、Tsuji Tokuji、Fukunaka Ayako、Yamazaki Tomohiro、Taylor Kathryn M.、Ogra Yasumitsu、Kambe Taiho
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 17 Pages: 5669-5684
- DOI
  10.1074/jbc.ra120.012610
- NAID
  120006850466
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08971, KAKENHI-PLANNED-19H05772, KAKENHI-PROJECT-17J06767, KAKENHI-PROJECT-19K06479, KAKENHI-PUBLICLY-19H05250, KAKENHI-PLANNED-19H05768, KAKENHI-PROJECT-18H03380, KAKENHI-PROJECT-19H02883, KAKENHI-PROJECT-19J01778
[Journal Article] Architectural RNAs for Membraneless Nuclear Body Formation2020
- Author(s)
  Yamazaki T., Nakagawa S., Hirose T.
- Journal Title
  
  Cold Spring Harbor Symposia on Quantitative Biology
  
  Volume: LXXXIV Pages: 1-11
- DOI
  10.1101/sqb.2019.84.039404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06479, KAKENHI-PROJECT-19K22374, KAKENHI-PROJECT-17H03630, KAKENHI-PUBLICLY-19H05250
[Journal Article] Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition2019
- Author(s)
  Modic Miha、Grosch Markus、Rot Gregor、Schirge Silvia、Lepko Tjasa、Yamazaki Tomohiro（中略）Hirose Tetsuro（20名中18番目）、Ule Jernej、Drukker Micha
- Journal Title
  
  Molecular Cell
  
  Volume: 74 Issue: 5 Pages: 951-965
- DOI
  10.1016/j.molcel.2019.03.041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03630, KAKENHI-PUBLICLY-19H05250
[Journal Article] Molecular anatomy of the architectural NEAT1 noncoding RNA: The domains, interactors, and biogenesis pathway required to build phase-separated nuclear paraspeckles2019
- Author(s)
  Hirose T., Yamazaki T., Nakagawa S.
- Journal Title
  
  WIREs RNA
  
  Volume: 10 Issue: 6
- DOI
  10.1002/wrna.1545
- NAID
  120006941691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06479, KAKENHI-PUBLICLY-19H05250
[Journal Article] Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation2018
- Author(s)
  Yamazaki Tomohiro、Souquere Sylvie、Chujo Takeshi、Kobelke Simon、Chong Yee Seng、Fox Archa H.、Bond Charles S.、Nakagawa Shinichi、Pierron Gerard、Hirose Tetsuro
- Journal Title
  
  Molecular Cell
  
  Volume: 70 Issue: 6 Pages: 1038-1053
- DOI
  10.1016/j.molcel.2018.05.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15084, KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113002, KAKENHI-PLANNED-26113005, KAKENHI-PROJECT-17K19335, KAKENHI-PROJECT-17K15058, KAKENHI-INTERNATIONAL-15K21720, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H03630
[Journal Article] Molecular dissection of nuclear paraspeckles: towards understanding the emerging world of the RNP milieu.2018
- Author(s)
  Nakagawa S, Yamazaki T, Hirose T.
- Journal Title
  
  Open Biology
  
  Volume: 8 Issue: 10 Pages: 180150-180150
- DOI
  10.1098/rsob.180150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26113002, KAKENHI-PLANNED-26113005, KAKENHI-PROJECT-17H03604, KAKENHI-PROJECT-17K19335, KAKENHI-PROJECT-17K15058, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H03630
[Journal Article] 長鎖非コードRNAであるNEAT1の機能ドメインは相分離を介して核内構造体であるパラスペックルの形成をひき起こす2018
- Author(s)
  山崎智弘、廣瀬哲郎
- Journal Title
  
  First Author's
  
  Volume: - Pages: 070
- DOI
  10.7875/first.author.2018.070
- Open Access
- Data Source
  KAKENHI-PLANNED-26113002, KAKENHI-PROJECT-17K15058
[Journal Article] CRISPRa-mediated NEAT1 lncRNA upregulation induces formation of intact paraspeckles.2018
- Author(s)
  Yamazaki T, Fujikawa C, Kubota A, Takahashi A, Hirose T.
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 504 Issue: 1 Pages: 218-224
- DOI
  10.1016/j.bbrc.2018.08.158
- NAID
  120006725828
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26113002, KAKENHI-PROJECT-17K19335, KAKENHI-PROJECT-17K15058, KAKENHI-PROJECT-17H03630
[Journal Article] Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins2018
- Author(s)
  Chi B, O’Connell JD, Yamazaki T, Gangopadhyay J, Gygi SP, Reed R
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8755-8766
- DOI
  10.1038/s41598-018-27136-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15058
[Journal Article] Unusual semi‐extractability as a hallmark of nuclear body‐associated architectural noncoding RNAs2017
- Author(s)
  Chujo T, Yamazaki T, Kawaguchi T, Kurosaka S, Takumi T, Nakagawa S, Hirose T
- Journal Title
  
  The EMBO Journal
  
  Volume: - Issue: 10 Pages: 861-868
- DOI
  10.15252/embj.201695848
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113002, KAKENHI-PLANNED-26113005, KAKENHI-PROJECT-15J01473, KAKENHI-PROJECT-26291001, KAKENHI-PROJECT-15K18474, KAKENHI-PROJECT-17K19335, KAKENHI-PROJECT-17H03604, KAKENHI-PROJECT-17H03630, KAKENHI-PLANNED-16H06463, KAKENHI-PROJECT-16H06316
[Journal Article] Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells.2017
- Author(s)
  S. Saitoh, T. Maruyama, Y. Yako, M. Kajita, Y. Fujioka, Y. Ohba, N. Kasai, N. Sugama, S. Kon, S. Ishikawa, T. Hayashi, T. Yamazaki, M. Tada and Y. Fujita.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 114 Issue: 12
- DOI
  10.1073/pnas.1602349114
- NAID
  120006346108
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01248, KAKENHI-ORGANIZER-26114001, KAKENHI-PLANNED-26114008, KAKENHI-PROJECT-26250026, KAKENHI-PROJECT-16H06227, KAKENHI-PROJECT-14J02366, KAKENHI-PROJECT-14J02420, KAKENHI-PROJECT-26293041, KAKENHI-PROJECT-15K15023, KAKENHI-PROJECT-15K18474, KAKENHI-PROJECT-16K19571, KAKENHI-INTERNATIONAL-15K21757, KAKENHI-PROJECT-15KK0290, KAKENHI-PROJECT-17K19507, KAKENHI-PUBLICLY-17H05611, KAKENHI-PROJECT-17H04016
[Journal Article] Architectural RNAs (arcRNAs): A class of long noncoding RNAs that functions as the scaffold of nuclear bodies2016
- Author(s)
  Takeshi Chujo, Tomohiro Yamazaki, Tetsuro Hirose
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1859 Issue: 1 Pages: 139-146
- DOI
  10.1016/j.bbagrm.2015.05.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18474, KAKENHI-PROJECT-15J01473, KAKENHI-PROJECT-26650001, KAKENHI-PROJECT-26291001, KAKENHI-PLANNED-26113002
[Journal Article] Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter2016
- Author(s)
  Nishito Y, Tsuji N, Fujishiro H, Takeda T, Yamazaki T, Teranishi F, Okazaki F, Matsunaga A, Tuschl K, Rao R, Kono S, Miyajima H, Narita H, Himeno S, Kambe T
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 28 Pages: 14773-14787
- DOI
  10.1074/jbc.m116.728014
- NAID
  120006376011
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04501, KAKENHI-PROJECT-15K18474, KAKENHI-PROJECT-15K08054
[Journal Article] The building process of the functional paraspeckle with long non-coding RNAs2015
- Author(s)
  Yamazaki T, Hirose T
- Journal Title
  
  Frontiers in Bioscience
  
  Volume: 7 Issue: 1 Pages: 1-47
- DOI
  10.2741/715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26891001
[Journal Article] U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish2015
- Author(s)
  Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer-Hurt ME, Yin S, Eliasse Y, Adams E, Shaw CE, Reed R
- Journal Title
  
  Nucleic Acid Research
  
  Volume: 43 Issue: 6 Pages: 3208-3218
- DOI
  10.1093/nar/gkv157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26891001
[Presentation] Large-scale identification of RNA-binding proteins that initiate the formation of biomoleuclar condensates in cells2023
- Author(s)
  山崎智弘
- Organizer
  第1回関西RNA club
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04258
[Presentation] Large-scale identification of RNA-binding proteins that initiate the formation of biomoleuclar condensates in cells2023
- Author(s)
  山崎智弘
- Organizer
  第1回関西RNA club
- Invited
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] Biomolecular condensates with RNA scaffolds: towards a theoretical and systematic understanding of their formation and function2023
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hiro Takakuwa, Hyura Yoshino, Sylvie Souquere, Wakana Isshiki, Rie Doi, Mizuki Iwata, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  28th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18112
[Presentation] 物理理論と構成的アプローチを用いたRNAを足場とする非膜性構造体の作動原理の理解2023
- Author(s)
  山崎智弘、山本哲也、高桑央、吉野彪羅、Sylvie Souquere、土井理恵、岩田瑞季、一色和奏、梅崎創太、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18112
[Presentation] Formation mechanisms of SARS-CoV-2 viral RNPs with cellular host proteins2023
- Author(s)
  山崎智弘、土井理恵、廣瀬哲郎
- Organizer
  大阪大学先導的学際研究機構 RNAフロンティアサイエンス部門第一回 RNA-FSシンポジウム RNA研究が拓く生命科学
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] Biomolecular condensates scaffolded by RNAs: Towards a theoretical and systematic understanding of their formation and function2023
- Author(s)
  Tomohiro Yamzaki, Tetsuya Yamamoto, Hyura Yoshino, Hiro Takakuwa, Sylvie Souquere, Wakana Isshiki, Mizuki Iwata, Rie Doi, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  28th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04258
[Presentation] パラスペックルのミセル構造と形態を規定するNEAT1_2 RNAドメインマッピング2023
- Author(s)
  梅崎創太、山崎智弘、高桑央、廣瀬哲郎
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K18112
[Presentation] 物理理論と構成的アプローチを用いたRNAを足場とする非膜性構造体の作動原理の理解2023
- Author(s)
  山崎智弘、山本哲也、高桑央、吉野彪羅、Sylvie Souquere、土井理恵、岩田瑞季、一色和奏、梅崎創太、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04258
[Presentation] Formation mechanisms of SARS-CoV-2 viral RNPs with cellular host proteins2023
- Author(s)
  山崎智弘、土井理恵、廣瀬哲郎
- Organizer
  大阪大学先導的学際研究機構 RNAフロンティアサイエンス部門第一回 RNA-FSシンポジウム RNA研究が拓く生命科学
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Presentation] パラスペックルのミセル構造と形態を規定するNEAT1_2 RNAドメインマッピング2023
- Author(s)
  梅崎創太、山崎智弘、高桑央、廣瀬哲郎
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-23H04258
[Presentation] Large-scale identification of RNA-binding proteins that initiate the formation of biomolecular condensates in cells2023
- Author(s)
  山崎智弘
- Organizer
  第1回関西RNA club
- Invited
- Data Source
  KAKENHI-PROJECT-23K18112
[Presentation] 物理理論と構成的アプローチを用いたRNAを足場とする非膜性構造体の作動原理の理解2023
- Author(s)
  山崎智弘、山本哲也、高桑央、吉野彪羅、Sylvie Souquere、土井理恵、岩田瑞季、一色和奏、梅崎創太、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] パラスペックルのミセル構造と形態を規定するNEAT1_2 RNAドメインマッピング2023
- Author(s)
  梅崎創太、山崎智弘、高桑央、廣瀬哲郎
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] Large-scale identification of RNA-binding proteins that initiate the formation of biomoleuclar condensates in cells2023
- Author(s)
  Tomohiro Yamzaki, Doi Rie, Mizuki Iwata, Wakana Isshiki, Hiro Takakuwa, Tetsuro Hirose
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PUBLICLY-23H04258
[Presentation] Biomolecular condensates scaffolded by RNAs: Towards a theoretical and systematic understanding of their formation and function2023
- Author(s)
  Tomohiro Yamzaki, Tetsuya Yamamoto, Hyura Yoshino, Hiro Takakuwa, Sylvie Souquere, Wakana Isshiki, Mizuki Iwata, Rie Doi, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  28th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] Large-scale identification of RNA-binding proteins that initiate the formation of biomoleuclar condensates in cells2023
- Author(s)
  Tomohiro Yamzaki, Doi Rie, Mizuki Iwata, Wakana Isshiki, Hiro Takakuwa, Tetsuro Hirose
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] Large-scale identification of RNA-binding proteins that initiate the formation of biomolecular condensates in cells2023
- Author(s)
  Tomohiro Yamazaki, Rie Doi, Mizuki Iwata, Wakana Isshiki, Hiro Takakuwa, Tetsuro Hirose
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K18112
[Presentation] Biomolecular condensates scaffolded by RNAs: towards their theoretical and systematic understandings2022
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hyura Yoshino, Hiro Takakuwa, Sylvie Souquere, Wakana Isshiki, Mizuki Iwata, Rie Doi, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] RNAs as scaffolds of biomolecular condensates: Lessons from paraspeckles scaffolded by NEAT1_2 lncRNAs2022
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hiro Takakuwa, Hyura Yoshino, Wakana Isshiki, Sylvie Souquere, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  RNAフロンティアミーティング2021
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Presentation] RNAs as scaffolds of biomolecular condensates: Lessons from paraspeckles scaffolded by NEAT1_2 lncRNAs2022
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hiro Takakuwa, Hyura Yoshino, Wakana Isshiki, Sylvie Souquere, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  RNAフロンティアミーティング2021
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] Biomolecular condensates scaffolded by RNAs: towards their theoretical and systematic understandings2022
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hyura Yoshino, Hiro Takakuwa, Sylvie Souquere, Wakana Isshiki, Mizuki Iwata, Rie Doi, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Presentation] RNAを設計図とする非膜オルガネラの形成原理2022
- Author(s)
  山崎智弘、山本哲也、吉野彪羅、高桑央、Sylvie Souquere、土井理恵、岩田瑞季、一色和奏、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  RNAフロンティアミーティング2022
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Presentation] 理論と構成的アプローチを用いたRNAを足場とする非膜オルガネラの形成原理の解析2022
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hyura Yoshino, Hiro Takakuwa, Sylvie Souquere, Wakana Isshiki, Mizuki Iwata, Rie Doi, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  5回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Presentation] 理論と構成的アプローチを用いたRNAを足場とする非膜オルガネラの形成原理の解析2022
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Hyura Yoshino, Hiro Takakuwa, Sylvie Souquere, Wakana Isshiki, Mizuki Iwata, Rie Doi, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] RNAを設計図とする非膜オルガネラの形成原理2022
- Author(s)
  山崎智弘、山本哲也、吉野彪羅、高桑央、Sylvie Souquere、土井理恵、岩田瑞季、一色和奏、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  RNAフロンティアミーティング
- Data Source
  KAKENHI-PROJECT-23K23809
[Presentation] Paraspeckles are constructed as block copolymer micelles2021
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Sylvie Souquere, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] RNAs as scaffolds of biomolecular condensates: from LLPS to micellization2021
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Sylvie Souquere, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  MBSJ2021
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] Paraspeckles are constructed as block copolymer micelles2021
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Sylvie Souquere, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Presentation] RNAs as scaffolds of biomolecular condensates: from LLPS to micellization2021
- Author(s)
  Tomohiro Yamazaki, Tetsuya Yamamoto, Sylvie Souquere, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  MBSJ2021
- Data Source
  KAKENHI-PUBLICLY-21H00253
[Presentation] Paraspeckles: RNA-scaffolding microphase-separated condensates2020
- Author(s)
  山崎智弘
- Organizer
  MBSJ2020
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] Paraspeckles: RNA-scaffolding microphase-separated condensates2020
- Author(s)
  山崎智弘
- Organizer
  MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] 相分離構造体パラスペックルの性状・機能を規定するNEAT1 lncRNAモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、小松リチャード馨、吉野彪羅、Archa H Fox、Charles S Bond、中川真一、齋藤博英、Gerard Pierron、廣瀬哲郎
- Organizer
  RNAフロンティアミーティング2019
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] Formation and function of RNA-induced phase-separated nuclear bodies2019
- Author(s)
  Tomohiro Yamazaki, Sylvie Souquere, Hiro Takakuwa, Hyura Yoshino, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] Hidden codes of NEAT1 lncRNA for biophysical properties of phase-separated paraspeckles.2019
- Author(s)
  Yamazaki T, Souquere S, Takakuwa H, Yoshino H, Fox AH, Bond CS, Nakagawa S, Pierron G, Hirose T.
- Organizer
  RNA2019 (24th Annual Meeting of the RNA Society)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] 相分離構造体パラスペックルの性状・機能を規定するNEAT1 lncRNAモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、小松リチャード馨、吉野彪羅、Archa H Fox、Charles S Bond、中川真一、齋藤博英、Gerard Pierron、廣瀬哲郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] Design Principles of Architectural RNAs for Phase-separated Paraspeckle Nuclear Bodies.2019
- Author(s)
  Yamazaki T
- Organizer
  Tokyo RNA Club, The 26th Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] 相分離構造体パラスペックルの性状・機能を規定するNEAT1 lncRNAモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、小松リチャード馨、吉野彪羅、Archa H. Fox、Charles S. Bond、中川真一、齊藤博英、Gerard Pierron、廣瀬哲郎
- Organizer
  第５回北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] Design principles of arhitectural RNAs for phase-separated paraspeckle nuclear bodies2019
- Author(s)
  山崎智弘
- Organizer
  Tokyo RNA Club, The 26th meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] Hidden codes of NEAT1 lncRNA for biophysical properties of phase-separated paraspeckles2019
- Author(s)
  Tomohiro Yamazaki, Sylvie Souquere, Hiro Takakuwa, Hyura Yoshino, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  RNA2019
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] 相分離構造体パラスペックルの性状・機能を規定するNEAT1 lncRNAモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、小松リチャード馨、吉野彪羅、Archa H Fox、Charles S Bond、中川真一、齋藤博英、Gerard Pierron、廣瀬哲郎
- Organizer
  第５回北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] 相分離構造体パラスペックルの性状・機能を規定するNEAT1 lncRNAモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、小松リチャード馨、吉野彪羅、Archa H. Fox、Charles S. Bond、中川真一、齊藤博英、Gerard Pierron、廣瀬哲郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] 核内相分離構造体パラスペックルの生物物理的性質を規定するNEAT1 lncRNAのRNPモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、吉野彪羅、Archa H Fox、Charles S Bond、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] NEAT1 modular lncRNA domains dictate formation of phase-separated, distinct, highly ordered paraspeckle2019
- Author(s)
  Tomohiro Yamazaki, Sylvie Souquere, Hyura Yoshino, Hiro Takakuwa, Takeshi Chujo, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  The 20th Takeda Science Foundation Symposium on Bioscience: RNA Neobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] Formation and function of RNA-induced phase-separated nuclear bodies.2019
- Author(s)
  Yamazaki T, Souquere S, Takakuwa H, Yshino H, Fox AH, Bond CS, Nakagawa S, Pierron G, Hirose T.
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06479
[Presentation] 相分離構造体パラスペックルの性状・機能を規定するNEAT1 lncRNAモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、小松リチャード馨、吉野彪羅、Archa H. Fox、Charles S. Bond、中川真一、齊藤博英、Gerard Pierron、廣瀬哲郎
- Organizer
  RNAフロンティアミーティング2019
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] 核内相分離構造体パラスペックルの生物物理的性質を規定するNEAT1 lncRNAのRNPモジュール2019
- Author(s)
  山崎智弘、高桑央、Sylvie Souquere、吉野彪羅、Archa H. Fox、Charles S. Bond、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  日本RNA学会2019
- Data Source
  KAKENHI-PUBLICLY-19H05250
[Presentation] 核内構造体パラスペックルはNEAT1 lncRNAの複数の機能RNAドメインが協働することにより構築される2018
- Author(s)
  山崎智弘、Sylvie Souquere、吉野彪羅、高桑央、中條岳志、Archa H. Fox、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第３回北大部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] Dissection of NEAT1 lncRNA domains to establish distinct, highly ordered, phase-separated paraspeckle nuclear body2018
- Author(s)
  山崎智弘、Sylvie Souquere、吉野彪羅、高桑央、木立尚孝、Archa H. Fox、Charles S. Bond、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  Keystone symposium Noncoding RNAs: Form, Function, Physiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] 核内構造体パラスペックルはNEAT1 lncRNAの複数のモジュールドメインの協調した機能により構築される2018
- Author(s)
  山崎智弘、Sylvie Souquere、吉野彪羅、高桑央、中條岳志、Archa H. Fox、Charles S. Bond、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] 核内構造体パラスペックルはNEAT1 lncRNAの複数のモジュールドメインの協調した機能により構築される2018
- Author(s)
  山崎智弘、Sylvie Souquere、吉野彪羅、高桑央、中條岳志、Archa H. Fox、Charles S. Bond、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  RNAフロンティアミーティング2018
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] NEAT1 lncRNA 機能ドメイン上での NONO オリゴマー化が相分離した核内構造体パラスぺックル形成を誘導する2018
- Author(s)
  山崎智弘、Sylvie Souquere、吉野彪羅、高桑央、中條岳志、Archa H. Fox、Charles S. Bond、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第 20 回日本 RNA 学会年会
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] Multiple NEAT1 modular RNA domains cooperatively construct phase-separated, distinct, highly ordered paraspeckle nuclear bodies2018
- Author(s)
  Tomohiro Yamazaki, Souquere Sylvie, Hiro Takakuwa, Hyura Yoshino, Takeshi Chujo, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  JAJ RNA 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] Functional domains of NEAT1 architectural lncRNA induce paraspeckle assembly through phase separation2018
- Author(s)
  Tomohiro Yamazaki, Sylvie Souquere, Hyura Yoshino, Hiro Takakuwa, Takeshi Chujo, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  The 13th International Symposium of the Institute Network for Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] NEAT1 lncRNAに潜むパラスペックル構築を司るRNAエレメント2017
- Author(s)
  山崎智弘、Sylvie Souquere、木立尚孝、Archa H. Fox, 中川真一, Gerard Pierron, 廣瀬哲郎
- Organizer
  第２回北大・部局横断シンポジウム「免疫・癌・感染」
- Place of Presentation
  北海道大学工学部鈴木章記念ホール（札幌市北区）
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] The specific region of architectural NEAT1 lncRNA induces the formation of the phase-separated paraspeckle nuclear body2017
- Author(s)
  Tomohiro Yamazaki, Taro Mannen, Sylvie Souquere, Hisanori Kiryu, Archa H. Fox, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第４３回内藤コンファレンス　非コードRNA：生物学、化学、そして疾患
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] The specific regions of architectural NEAT1 lncRNA induce the formation of the phase-separated paraspeckle nuclear body2017
- Author(s)
  山崎智弘、萬年太郎、Sylvie Souquere、木立尚孝、Archa H. Fox、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  第54回日本生化学会北海道支部例会
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] 核内構造体パラスペックルはNEAT1 lncRNAの複数の機能ドメインにより構築される2017
- Author(s)
  山崎智弘、Sylvie Souquere、木立尚孝、Archa H. Fox、中川真一、Gerard Pierron、廣瀬哲郎
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] Liquid-liquid phase separation induced by NEAT1 lncRNA that builds paraspeckle nuclear body2017
- Author(s)
  Tomohiro Yamazaki, Sylvie Souquere, Archa H. Fox, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  Phase Separation and RNA Processing as Drivers of Cancer and Neurodegenerative Disease
- Place of Presentation
  Sanford Consortium (San Diego, CA, USA)
- Year and Date
  2017-02-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] The specific domains of architectural NEAT1 lncRNA induce the formation of the distinct phase-separated paraspeckle nuclear body2017
- Author(s)
  Tomohiro Yamazaki, Taro Mannen, Sylvie Souquere, Hisanori Kiryu, Archa H. Fox, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  RNA2017
- Place of Presentation
  Prague Congress Center（プラハ、チェコ）
- Year and Date
  2017-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] The specific domains of architectural NEAT1 lncRNA induces the formation of the distinct phase-separated paraspeckle nuclear body2017
- Author(s)
  Tomohiro Yamazaki, Taro Mannen, Sylvie Souquere, Hisanori Kiryu, Archa H. Fox, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  RNA2017 (The 22nd Annual Meeting of the RNA Society)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] NEAT1長鎖ノンコーディングRNAは液相分離を誘導することで核内構造体パラスペックルを構築する2017
- Author(s)
  山崎智弘、Sylvie Souquere 、木立尚孝、Archa H. Fox 、中川真一、Gerard Pierron 、廣瀬哲郎
- Organizer
  第19回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-17K15058
[Presentation] NEAT1 lncRNAに潜むパラスペックル構築を司るRNAエレメント2016
- Author(s)
  Tomohiro Yamazaki, Sylvie Souquere, Hisanori Kiryu, Yuki Baba, Kazuki Mugikura, Archa H. Fox, Charles S. Bond, Shinichi Nakagawa, Gerard Pierron, Tetsuro Hirose
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] CRISPR/Cas9-mediated dissection of NEAT1 lncRNA to identify “architectural” RNA elements2016
- Author(s)
  Tomohiro Yamazaki, Tetsuro Hirose
- Organizer
  Keystone Symposium: Noncoding RNAs in Health and Disease
- Place of Presentation
  Santa Fe (USA)
- Year and Date
  2016-02-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] Decoding “architectural” RNA elements in NEAT1 lncRNA2016
- Author(s)
  山崎智弘
- Organizer
  2016年日本生物物理学会北海道支部・日本生化学会北海道支部合同シンポジウム
- Place of Presentation
  北海道大学大学院薬学研究院（北海道札幌市）
- Year and Date
  2016-03-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] Decoding "architectural" RNA elements in NEAT1 lncRNA2016
- Author(s)
  Tomohiro Yamazaki, Sylvie Souquere, Archa H. Fox, Gerard Pierron, Shinichi Nakagawa, Tetsuro Hirose
- Organizer
  RNA2016
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] CRISPR/Cas9-mediated dissection of NEAT1 lncRNA to identify architectural RNA elements2015
- Author(s)
  Tomohiro Yamazaki, Tetsuro Hirose
- Organizer
  第38回日本分子生物学会年会（BMB2015）
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] RNA研究を続けて：生命科学研究科から研究キャリアをスタートして2015
- Author(s)
  山崎智弘
- Organizer
  平成27年度京都大学生命科学研究科リトリート
- Place of Presentation
  同志社大学びわこリトリートセンター（滋賀県大津市）
- Year and Date
  2015-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] CRISPR/Cas9システムを用いたNEAT1 lncRNAに潜む構造構築エレメントの探索2015
- Author(s)
  山崎智弘、廣瀬哲郎
- Organizer
  RNAフロンティアミーティング2015
- Place of Presentation
  タカミヤヴィレッジホテル樹林（山形県山形市蔵王温泉）
- Year and Date
  2015-12-08
- Data Source
  KAKENHI-PROJECT-15K18474
[Presentation] 核内構造体Gemが繋ぐ運動ニューロン病ALSとSMA
- Author(s)
  山崎　智弘、Yong Yu、Shi Chen、Bo Zhai、Rita Das、Christopher E. Shaw、Steve P. Gygi、Neil A. Shneider、Tom Maniatis、Robin Reed
- Organizer
  RNAフロンティアミーティング2014
- Place of Presentation
  ラフォーレ南紀白浜（和歌山県・西牟婁郡白浜町）
- Year and Date
  2014-09-16 – 2014-09-18
- Data Source
  KAKENHI-PROJECT-26891001
[Presentation] A molecular link between motor neuron diseases ALS and SMA
- Author(s)
  山崎　智弘、Yong Yu、Shi Chen、Bo Zhai、Rita Das、Christopher E. Shaw、Steve P. Gygi、Neil A. Shneider、Tom Maniatis、Robin Reed
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26891001

1. NAKAGAWA Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. YOSHIMOTO Rei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. FUKUNAKA Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 中條岳志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 二宮賢介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 広瀬哲郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
7. 山本哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 田中茂幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 大場雄介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 前田明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 神戸大朋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamazaki Tomohiro 山崎 智弘

Tomohiro Yamazaki 山崎 智弘

Research Projects

Research Products

Co-Researchers

細胞内相分離を誘導するタンパク質の大規模探索と誘導機構の解明Principal Investigator

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Regulatory mechanism of gene expression by membraneless organelles formed through micellizationPrincipal Investigator

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Mechanisms to define the structure, properties, and function of RNP biomolecular condensatesPrincipal Investigator

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Chromatin regulation by RNA-induced phase separationPrincipal Investigator

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Mechanisms of the principles to construct and design phase-separated RNP nanostructuresPrincipal Investigator

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Genome regulation by phase-separated nuclear RNP bodiesPrincipal Investigator

Principal Investigator

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Mechanisms for phase separation of RNA-induced nuclear bodiesPrincipal Investigator

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Identification of the RNA elements that determine semi-extractability of RNAsPrincipal Investigator

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プリオン様ドメインとRNAを介した核内構造体構築機構の解明Principal Investigator

Principal Investigator

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[Book] 「非ドメイン型arcRNAによる非膜オルガネラ形成」Meidcal Science Digest2023

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[Book] 「非ドメイン型arcRAによる非膜オルガネラ形成」Medical Science Digest2023

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[Book] セントラルドグマの新常識2022

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[Book] フロントランナー直伝 相分離解析プロトコール2022

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[Book] フロントランナー直伝 相分離解析プロトコール2022

Yamazaki Tomohiro 山崎智弘

Tomohiro Yamazaki 山崎智弘

[Book] フロントランナー直伝相分離解析プロトコール2022

[Book] フロントランナー直伝　相分離解析プロトコール2022

[Book] 月刊　細胞2021

[Book] 相分離　メカニズムと疾患2021

[Book] 相分離　メカニズムと疾患2021

[Book] 月刊　細胞2021