Muramatsu Tomoki 村松智輝

Researcher Number	90732553
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2021: 東京医科歯科大学, 難治疾患研究所, 助教 2014 – 2016: 東京医科歯科大学, 難治疾患研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Complex systems / Tumor diagnostics
Keywords	Principal Investigator がん転移 / 血管新生 / VEGFA / Hypusine経路 / がん治療 / 低酸素 / BETタンパク質 / BET阻害剤 / ハイスループットスクリーニング / 化合物スクリーニング … More / ライブラリースクリーニング / VEGAF / ニワトリ胚 / 翻訳後修飾 / RNA-ChIPシークエンス / タンパク質翻訳 / eIF5A / RNA-CｈIPシークエンス / 移動・浸潤 / 口腔扁平上皮がん / 翻訳制御 … More Except Principal Investigator マイクロRNA / 核酸医薬 / ゲノム / オートファジー / バイオマーカー / オミクス解析 / BETファミリ－蛋白 / DNA損傷修復 / BETファミリーBRD4 / 抗がん核酸製剤 / スーパーエンハンサー / miR-3140-3p / miR-1293 / DNA修復経路 / BRD4 / BETファミリー蛋白 / 抗癌性核酸医薬 / 癌 / 核酸創薬 / 既存薬再配置 / がん / システム生物学 / 浸潤・転移 / がん特性 / 核酸抗がん薬 / がん抑制型マイクロRNA / がん悪性特性 / DR / がん代謝異常 / オミクス / がん細胞文脈 / 分子標的治療 / DDS / 上皮間葉転換（EMT) / 細胞文脈 / 分子標的薬 / DNAメチル化 / エピゲノム / 癌抑制遺伝子 / 癌遺伝子 / 難治がん / ビメンチン / EMT / 治療標的 / p62 / 上皮間葉転換 / がん個別化医療 Less

Analysis of mechanisms of the hypoxic responses by BET proteinsPrincipal Investigator
- Principal Investigator
  
  村松智輝
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Exploring the transcriptional repressors of VEGFA by in vitro/in vivo high throughput screeningPrincipal Investigator
- Principal Investigator
  
  Muramatsu Tomoki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Development of therapeutic miRNAs targeting BET family protein BRD4 for cancer
- Principal Investigator
  
  Inazawa Johji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of mechanism of hypusine pathway in cancerPrincipal Investigator
- Principal Investigator
  
  Muramatsu Tomoki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
Establishment of novel concept for cancer diagnostics and therapeutics based on the systematic comprehension of cellular context in cancer
- Principal Investigator
  
  Inazawa Johji
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
新規がん治療標的経路として見出されたhypusine axisの分子機構の解明Principal Investigator
- Principal Investigator
  
  村松智輝
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
Comprehensive understanding of molecular carcinogenesis through omics analysis and development of molecular diagnostics for personalized medicine
- Principal Investigator
  
  Johji Inazawa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Tokyo Medical and Dental University

All 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book Patent

[Book] 日本臨床増刊号　がん転移学上「In vivo 選択法による高転移がん細胞亜株の分離2017
- Author(s)
  （分担）村松智輝, 稲澤譲治
- Total Pages
  305
- Publisher
  株式会社　日本臨床社
- ISBN
- Data Source
  KAKENHI-PLANNED-15H05908
[Book] 次世代がん治療研究最前線2017
- Author(s)
  村松智輝　稲澤譲治
- Publisher
  株式会社　エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-15K18401
[Book] 次世代がん治療「ハイプシン経路によるがん浸潤・転移メカニズム」2017
- Author(s)
  (分担）村松智輝, 稲澤譲治
- Total Pages
  386
- Publisher
  (株) エヌ・ティー・エス
- ISBN
  9784860435035
- Data Source
  KAKENHI-PLANNED-15H05908
[Journal Article] miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway2020
- Author(s)
  Takagawa Yuki、Gen Yasuyuki、Muramatsu Tomoki、Tanimoto Kousuke、Inoue Jun、Harada Hiroyuki、Inazawa Johji
- Journal Title
  
  Molecular Therapy
  
  Volume: 28 Issue: 6 Pages: 1494-1505
- DOI
  10.1016/j.ymthe.2020.04.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-18K06954
[Journal Article] Suppression of MET Signaling Mediated by Pitavastatin and Capmatinib Inhibits Oral and Esophageal Cancer Cell Growth2020
- Author(s)
  Xu Bo、Muramatsu Tomoki、Inazawa Johji
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 19 Issue: 4 Pages: 585-597
- DOI
  10.1158/1541-7786.mcr-20-0688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02688
[Journal Article] Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas2019
- Author(s)
  Tanimoto Kousuke、Muramatsu Tomoki、Inazawa Johji
- Journal Title
  
  Cancer Medicine
  
  Volume: 8 Issue: 17 Pages: 7372-7384
- DOI
  10.1002/cam4.2619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-18K15305
[Journal Article] Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk12019
- Author(s)
  Akatsu Y*, Takahashi N*, Yoshimatsu Y*, Kimuro S, Muramatsu T, Katsura A, Maishi N, Suzuki HI, Inazawa J, Hida K, Miyazono K, Watabe T. (＊equal contribution)
- Journal Title
  
  Molecular Oncology
  
  Volume: 13 Issue: 8 Pages: 1706-1724
- DOI
  10.1002/1878-0261.12504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07157, KAKENHI-PROJECT-18K09715, KAKENHI-PLANNED-15H05908, KAKENHI-PUBLICLY-18H05092, KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-18H02996
[Journal Article] Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line2018
- Author(s)
  Sato Taku、Muramatsu Tomoki、Tanabe Minoru、Inazawa Johji
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 11 Pages: 3623-3633
- DOI
  10.1111/cas.13783
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-18H02688
[Journal Article] miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein2018
- Author(s)
  Tonouchi Erina、Gen Yasuyuki、Muramatsu Tomoki、Hiramoto Hidekazu、Tanimoto Kousuke、Inoue Jun、Inazawa Johji
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 4482-4482
- DOI
  10.1038/s41598-018-22767-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14630, KAKENHI-PROJECT-15K19040, KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-18H02688
[Journal Article] miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer2017
- Author(s)
  Hiramoto Hidekazu、Muramatsu Tomoki、Ichikawa Daisuke、Tanimoto Kousuke、Yasukawa Satoru、Otsuji Eigo、Inazawa Johji
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s41598-017-04191-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-16K14630
[Journal Article] Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma.2017
- Author(s)
  Nagata H, Kozaki K, Muramatsu T, Hiramoto H, Tanimoto K, Fujiwara N, Imoto S, Ichikawa D, Otsuji E, Miyano S, Kawano T, Inazawa J
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05908
[Journal Article] Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma2017
- Author(s)
  Nagata Hiroaki、Kozaki Ken-Ichi、Muramatsu Tomoki、Hiramoto Hidekazu、Tanimoto Kousuke、Fujiwara Naoto、Imoto Seiya、Ichikawa Daisuke、Otsuji Eigo、Miyano Satoru、Kawano Tatsuyuki、Inazawa Johji
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 23 Pages: 37740-37750
- DOI
  10.18632/oncotarget.17147
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16K14630
[Journal Article] Significant impact of miRNA-target gene networks on genetics of human complex traits.2016
- Author(s)
  Okada Y, Muramatsu T, Suita N, Kanai M, Kawakami E et al.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 22223-22223
- DOI
  10.1038/srep22223
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14429, KAKENHI-PROJECT-15K21631, KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-15H05670
[Journal Article] The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.2016
- Author(s)
  Muramatsu T, Kozaki KI, Imoto S, Yamaguchi R, Tsuda H, Kawano T, Fujiwara N, Morishita M, Miyano S, Inazawa J.
- Journal Title
  
  Oncogene
  
  Volume: - Issue: 40 Pages: 5304-5316
- DOI
  10.1038/onc.2016.71
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18401, KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-25250019, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16K14630
[Journal Article] Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system2016
- Author(s)
  Morishita M, Muramatsu T, Suto Y, Hirai M, Konishi T, Hayashi S, Shigemizu D, Tsunoda T, Moriyama K, Inazawa J
- Journal Title
  
  Oncotarget
  
  Volume: 7(9) Issue: 9 Pages: 10182-92
- DOI
  10.18632/oncotarget.7186
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-26253093, KAKENHI-PROJECT-14J05209
[Journal Article] Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma.2016
- Author(s)
  Sakha S, Muramatsu T, Ueda K, Inazawa J:
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 38750-38750
- DOI
  10.1038/srep38750
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-26710007, KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-16K14630
[Journal Article] miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer2015
- Author(s)
  Yanaka Y, Muramatsu T, Uetake H, Kozaki K, Inazawa J
- Journal Title
  
  Carcinogenesis.
  
  Volume: 36 Issue: 11 Pages: 1363-71
- DOI
  10.1093/carcin/bgv106
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-26670815, KAKENHI-PROJECT-26293067
[Patent] 医薬組成物2020
- Inventor(s)
  稲澤　譲治、玄　泰之、井上　純、村松　智輝、高川　祐希
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02688
[Patent] がん用医薬組成物2020
- Inventor(s)
  稲澤　譲治、村松　智輝、徐　博
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-107768
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H02688
[Patent] 医薬組成物2019
- Inventor(s)
  稲澤譲治、玄泰之、井上純、村松智輝、高川祐希
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-233250
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02688
[Patent] 医薬組成物2019
- Inventor(s)
  稲澤譲治、玄泰之、井上純、村松智輝、高川祐希
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-233250
- Filing Date
  2019
- Data Source
  KAKENHI-PLANNED-15H05908
[Patent] マイクロＲＮＡ及びその誘導体を有効成分とする医薬組成物2018
- Inventor(s)
  稲澤譲治、玄泰行、村松智輝、外内えり奈
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PLANNED-15H05908
[Patent] マイクロＲＮＡ及びその誘導体を有効成分とする医薬組成物2018
- Inventor(s)
  稲澤譲治、玄泰行、村松智輝、外内えり奈
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02688
[Patent] マイクロＲＮＡ及びその誘導体を有効成分とする医薬組成物2018
- Inventor(s)
  稲澤譲治、玄泰行、村松智輝、外内えり奈
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PLANNED-15H05908
[Patent] マイクロＲＮＡ及びその誘導体を有効成分とする医薬組成物2018
- Inventor(s)
  稲澤譲治、玄泰行、村松智輝、外内えり奈
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02688
[Patent] マイクロRNA及びその誘導体を有効成分とするがん治療剤2017
- Inventor(s)
  稲澤譲治、玄泰行、村松智輝、外内えり奈
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学、株式会社ビー・エム・エル
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-229046
- Filing Date
  2017
- Data Source
  KAKENHI-PLANNED-15H05908
[Patent] 食道がんのリンパ節転移可能性のデータ取得方法2017
- Inventor(s)
  稲澤譲治、村松智輝、永田啓明、谷本幸介、河野辰幸　他2名
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学、株式会社ビー・エム・エル
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-036122
- Filing Date
  2017-02-28
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] Exploring the transcriptional inhibitors of VEGFA with chemical compound libraries2021
- Author(s)
  Tomoki Muramatsu, Johji Inazawa
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07093
[Presentation] FDA承認薬ライブラリーから見出したピタバスタチンの抗腫瘍効果についての機能解析2020
- Author(s)
  村松智輝、稲澤譲治
- Organizer
  第24回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 口腔・食道がんにおいてピタバスタチンは AKT、ERK のシグナルを抑制し、細胞増殖を阻害する2020
- Author(s)
  村松智輝、徐博、稲澤譲治
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] Exploring novel tumor suppressive microRNAs in OSCC2019
- Author(s)
  Takagawa Y, Gen Y, Muramatsu T, Harada H, Inazawa J.
- Organizer
  The 3rd International Symposium of International Society of Precision Cancer Medicine 2019
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 線維芽細胞増殖因子(FGF2)は腫瘍血管内皮細胞において TGF-b によって誘導される内皮-筋線維芽移行を制御する2019
- Author(s)
  吉松康裕、赤津裕一、高橋直也、紀室志織、村松智輝、桂彰宏、間石奈湖、鈴木洋、稲澤譲治、樋田京子、宮園浩平、渡部徹郎
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 扁平上皮がん細胞においてピタバスタチンは AKT、ERK の抑制を介して細胞増殖を阻害する2019
- Author(s)
  徐博、村松智輝、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 機能的 miRNA ライブラリースクリーニングによる、BRD4 を標的とする新規癌抑制型 miRNA の同定2019
- Author(s)
  高川祐希、玄泰行、村松智輝、原田浩之、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 核酸抗癌薬を目指した新規腫瘍抑制型 miRNA の探索2019
- Author(s)
  玄泰行、村松智輝、井上純、稲澤譲治
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 線維芽細胞増殖因子(FGF2)は腫瘍血管内皮細胞において TGF-b によって誘導される内皮-筋線維芽移行を制御する2019
- Author(s)
  吉松康裕、赤津裕一、高橋直也、紀室志織、村松智輝、桂彰宏、間石奈湖、鈴木洋、稲澤譲治、樋田京子、宮園浩平、渡部徹郎
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 膵臓癌細胞株(Panc-1)から樹立したCTC 亜株における TGFBI の機能解析2019
- Author(s)
  村松智輝、稲澤譲治
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 扁平上皮がん細胞においてピタバスタチンは AKT、ERK の抑制を介して細胞増殖を阻害する2019
- Author(s)
  徐博、村松智輝、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 統合的 mRNA, miRNA 発現情報を基盤とした独自のマイクロ RNA標的遺伝子予測データベースの構築2019
- Author(s)
  内藤諒、村松智輝、谷本幸介、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 循環腫瘍細胞亜株 (Panc-1-CTC)の発現解析から見出した TGFBIの機能解析2019
- Author(s)
  村松智輝、佐藤拓、田邉稔、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] Identification and characterization of TGFBI in circulating tumor cell subline from pancreatic cancer cell line2019
- Author(s)
  Muramatsu T, Sato T, Tanabe M, Inazawa J
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 新規癌抑制型 miRNA による MYC 標的核酸抗癌治療の可能性2019
- Author(s)
  玄泰行、村松智輝、井上純、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 核酸抗癌薬を目指した新規腫瘍抑制型 miRNA の探索2019
- Author(s)
  玄泰行、村松智輝、井上純、稲澤譲治
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 新規癌抑制型 miRNA による MYC 標的核酸抗癌治療の可能性2019
- Author(s)
  玄泰行、村松智輝、井上純、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 膵臓癌細胞株(Panc-1)から樹立したCTC 亜株における TGFBI の機能解析2019
- Author(s)
  村松智輝、稲澤譲治
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 循環腫瘍細胞亜株 (Panc-1-CTC)の発現解析から見出した TGFBIの機能解析2019
- Author(s)
  村松智輝、佐藤拓、田邉稔、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] Identification and characterization of TGFBI in circulating tumor cell subline from pancreatic cancer cell line2019
- Author(s)
  Muramatsu T, Sato T, Tanabe M, Inazawa J
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 機能的 miRNA ライブラリースクリーニングによる、BRD4 を標的とする新規癌抑制型 miRNA の同定2019
- Author(s)
  高川祐希、玄泰行、村松智輝、原田浩之、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] 統合的 mRNA, miRNA 発現情報を基盤とした独自のマイクロ RNA標的遺伝子予測データベースの構築2019
- Author(s)
  内藤諒、村松智輝、谷本幸介、稲澤譲治
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] Exploring novel tumor suppressive microRNAs in OSCC.2019
- Author(s)
  Takagawa Y, Gen Y, Muramatsu T, Harada H, Inazawa J
- Organizer
  The 3rd International Symposium of International Society of Precision Cancer Medicine 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 口腔扁平上皮癌における新規のがん抑制型マイクロRNAの探索2018
- Author(s)
  髙川祐希、玄泰行、村松智輝、原田浩之、稲澤譲治
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 口腔扁平上皮癌における新規のがん抑制型マイクロRNAの探索2018
- Author(s)
  髙川祐希、玄泰行、村松智輝、原田浩之、稲澤譲治
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein2018
- Author(s)
  Muramatsu T, Tonouchi E, Gen Y, Hiramoto H, Tanimoto K, Inoue J, Inazawa J
- Organizer
  AACR Annual Meeting 2018
- Data Source
  KAKENHI-PROJECT-18H02688
[Presentation] miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein2018
- Author(s)
  Muramatsu T, Tonouchi E, Gen Y, Hiramoto H, Tanimoto K, Inoue J, Inazawa J
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 機能的miRNA ライブラリースクリーニングを用いた、BET family 遺伝子を制御するがん抑制型miRNA の同定2017
- Author(s)
  外内えり奈、村松智輝、玄泰行、平本秀一、稲澤譲治.
- Organizer
  第76 回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] miR-509-5p とmiR-1243 は膵癌においてEMT を抑制する2017
- Author(s)
  平本秀一、村松智輝、市川大輔、大辻英吾、稲澤譲治
- Organizer
  第76 回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] Exploring target genes of eukaryotic initiation factor 5A in cancer using RNA sequence analysis2016
- Author(s)
  Muramatsu T, Tanimoto K, Inazawa J
- Organizer
  AACR
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] MicroRNAを介したBET familyとmTOR経路阻害によるがん細胞増殖抑制機構2016
- Author(s)
  外内えり奈、村松智輝、平本秀一、稲澤譲治
- Organizer
  第75回日本癌学会学術総会.
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] Exploring target genes of eukaryotic initiation factor 5A in cancer using RNA sequence analysis2016
- Author(s)
  Muramatsu T, Tanimoto K, Inazawa J
- Organizer
  AACR2016 Annual Meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] Significant impact of miRNA-target gene networks on genetics of human complex traits2016
- Author(s)
  Kanai M, Okada Y, Muramatsu T, Suita N, Kawakami E, Iotchkova V, Soranzo N, Inazawa J, Tanaka T
- Organizer
  ICHG
- Place of Presentation
  国立京都国際会館, 京都
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] Significant impact of miRNA-target gene networks on genetics of human complex traits2016
- Author(s)
  Kanai M, Okada Y, Muramatsu T, Suita N, Kawakami E, Iotchkova V, Soranzo N, Inazawa J, Tanaka T
- Organizer
  ICHG
- Place of Presentation
  国立京都国際会館, 京都
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] 細胞ベースのレポーターシステムとmiRNAライブラリーを用いてのEMT抑制miRNAの探索2016
- Author(s)
  平本秀一、村松智輝、市川大輔、大辻英吾、稲澤譲治
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] Exploring target genes of eukaryotic initiation factor 5A in cancer using RNA sequence analysis2016
- Author(s)
  Muramatsu T, Tanimoto K, Inazawa J
- Organizer
  AACR
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] Exploring target genes of eukaryotic initiation factor 5A in cancer using RNA sequence analysis2016
- Author(s)
  Tomoki Muramatsu, Kousuke Tanimoto and Johji Inazawa
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18401
[Presentation] がん転移におけるマイクロRNAとWNT経路の役割2016
- Author(s)
  村松智輝、小崎健一、稲澤譲治
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PLANNED-15H05908
[Presentation] Chromothripsis-like pattern in cancer-cell genome after irradiation by a focused vertical micro-beam system SPICE2015
- Author(s)
  Morishita M、Muramatsu T、Hayashi S、Inazawa J
- Organizer
  he 34th Sapporo International Cancer Symposium
- Place of Presentation
  ロイトン札幌, 札幌
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] 扁平上皮がんにおけるハイプシン経路の活性は、RhoAシグナルを介してがん悪性化を促進する2015
- Author(s)
  村松智輝、小崎健一、井元清哉、山口類、津田均、河野辰幸、藤原直人、森下真紀、宮野悟、稲澤譲治
- Organizer
  第60回大会　日本人類遺伝学会
- Place of Presentation
  東京都新宿区　京王プラザホテル
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-15K18401
[Presentation] Exploring EMT-related miRNAs using cell-based reporter system in pancreatic cancer2015
- Author(s)
  Hiramoto H、Muramatsu T、Inazawa J
- Organizer
  The 34th Sapporo International Cancer Symposium
- Place of Presentation
  ロイトン札幌, 札幌
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma2015
- Author(s)
  Tomoki Muramatsu, Ken-ichi Kozaki, Seiya Imoto, Rui Yamaguchi, Hitoshi Tsuda, Tatsuyuki Kawano, Maki Morishita, Satoru Miyano, and Johji Inazawa
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Pennsylvania Convention Center Philadelphia, Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18401
[Presentation] Characterization of circulating tumor cell phenotype in pancreatic canccer.2015
- Author(s)
  Sato T、Muramatsu T、Inazawa J
- Organizer
  The 34th Sapporo International Cancer Symposium
- Place of Presentation
  ロイトン札幌, 札幌
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] Highly metastatic cancer cell exosomes contribute to cancer cell growth and metastatic traits2015
- Author(s)
  Sujata S、Muramatsu T、Inazawa J
- Organizer
  The 34th Sapporo International Cancer Symposium
- Place of Presentation
  ロイトン札幌, 札幌
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma2015
- Author(s)
  Muramatsu T、Inazawa J
- Organizer
  The 34th Sapporo International Cancer Symposium
- Place of Presentation
  ロイトン札幌, 札幌
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma2015
- Author(s)
  Tomoki Muramatsu, Ken-ichi Kozaki, Seiya Imoto, Rui Yamaguchi, Hitoshi Tsuda, Tatsuyuki Kawano, Naoto Fujiwara, Maki Morishita, Satoru Miyano, and Johji Inazawa
- Organizer
  第34回　札幌国際がんシンポジウム
- Place of Presentation
  北海道札幌市　ロイトン札幌
- Year and Date
  2015-06-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18401
[Presentation] 高転移腫瘍における統合的解析から同定された新規治療標的経路ハイプシンカスケードの解析
- Author(s)
  村松智輝
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26890012
[Presentation] The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.
- Author(s)
  Muramatsu T.Kozaki K. Imoto S.Yamaguchi R. Tsuda H.Kawano T. Morishita M.Miyano S. Inazawa J
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Philadelphia, USA.
- Year and Date
  2015-04-18 – 2015-04-22
- Invited
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] 口腔がん細胞株に認められた19番染色体の増幅領域に座位する遺伝子は、Rhoシグナル経路を介して転移に寄与している可能性がある．
- Author(s)
  村松智輝、稲澤譲治　他
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜．神奈川
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] Exploration of mechanisms for chromothripsis by irradiation
- Author(s)
  Morishita M. Muramatsu T. Hayashi S. Hirai M. Suto Y. Konishi T. Moriyama K. Inazawa J
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Invited
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] Chromosome 19 amplicon in oral cancer cell line have the potential to promote metastasis via Rho signaling pathway.
- Author(s)
  村松智輝、稲澤譲治　他
- Organizer
  平成25年度文部科学省科学研究費補助金・新学術領域研究「がん研究分野の特性等を踏まえた支援活動」. がん若手研究者ワークショップ
- Place of Presentation
  蓼科グランドホテル滝の湯．長野
- Data Source
  KAKENHI-PROJECT-25250019
[Presentation] the hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma
- Author(s)
  Tomoki Muramatsu
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Pennsylvania Convention Center Philadelphia, PA, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-26890012

1. Johji Inazawa (30193551)

# of Collaborated Projects: 3 results

# of Collaborated Products: 58 results
2. Inoue Jun (50568326)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. Tanimoto Kosuke (60611613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 玄泰行 (80596156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. Kozaki Ken-ichi (50270715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 岡田随象

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 吉松康裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Muramatsu Tomoki 村松 智輝

Research Projects

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Co-Researchers

Analysis of mechanisms of the hypoxic responses by BET proteinsPrincipal Investigator

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Exploring the transcriptional repressors of VEGFA by in vitro/in vivo high throughput screeningPrincipal Investigator

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Development of therapeutic miRNAs targeting BET family protein BRD4 for cancer

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Analysis of mechanism of hypusine pathway in cancerPrincipal Investigator

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Establishment of novel concept for cancer diagnostics and therapeutics based on the systematic comprehension of cellular context in cancer

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新規がん治療標的経路として見出されたhypusine axisの分子機構の解明Principal Investigator

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Comprehensive understanding of molecular carcinogenesis through omics analysis and development of molecular diagnostics for personalized medicine

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[Book] 日本臨床増刊号 がん転移学上「In vivo 選択法による高転移がん細胞亜株の分離2017

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[Book] 次世代がん治療研究最前線2017

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[Book] 次世代がん治療「ハイプシン経路によるがん浸潤・ 転移メカニズム」2017

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[Journal Article] miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway2020

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[Journal Article] Suppression of MET Signaling Mediated by Pitavastatin and Capmatinib Inhibits Oral and Esophageal Cancer Cell Growth2020

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[Journal Article] Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas2019

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[Journal Article] Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk12019

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Muramatsu Tomoki 村松智輝

[Book] 日本臨床増刊号　がん転移学上「In vivo 選択法による高転移がん細胞亜株の分離2017

[Book] 次世代がん治療「ハイプシン経路によるがん浸潤・転移メカニズム」2017