Narumi Katsuya 鳴海克哉

Researcher Number	90746752
Other IDs
Affiliation (Current)	2025: 北海道大学, 薬学研究院, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 北海道大学, 薬学研究院, 講師 2018 – 2020: 北海道大学, 薬学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 47040:Pharmacology-related / Basic Section 38050:Food sciences-related
Keywords	Principal Investigator 薬物相互作用 / 一塩基多型 / アルデヒドオキシダーゼ / アザチオプリン / 有害事象自発報告データベース / トランスポーター / SNP / 肝障害 / メトトレキサート / 機能性食品 … More / 補完代替療法 / エストロゲン / 有機アニオン輸送ポリペプチド / ポリフェノール / 乳酸 / モノカルボン酸トランスポーター / 乳がん Less

Research Projects
(3 results)
Research Products
(17 results)

AOX1の新規SNP機能解析および副作用予測因子としての薬物動態学的意義の検証Principal Investigator
- Principal Investigator
  
  鳴海克哉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hokkaido University
Pharmacogenetic analysis of pharmacokinetic factors related with methotrexate-induced toxicityPrincipal Investigator
- Principal Investigator
  
  Narumi Katsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Hokkaido University
Application of complementary and alternative medicine for breast cancer based on kinetic characteristics of food componentsPrincipal Investigator
- Principal Investigator
  
  Narumi Katsuya
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Comparative study on the occurrence of adverse effects in the concomitant use of azathioprine and aldehyde oxidase inhibitors2023
- Author(s)
  Ueda Hinata、Narumi Katsuya、Asano Shuho、Saito Yoshitaka、Furugen Ayako、Kobayashi Masaki
- Journal Title
  
  Expert Opinion on Drug Safety
  
  Volume: 23 Issue: 1 Pages: 89-97
- DOI
  10.1080/14740338.2023.2295976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23KJ0039, KAKENHI-PROJECT-23K06229
[Journal Article] The rs35217482 (T755I) single-nucleotide polymorphism in aldehyde oxidase-1 attenuates protein dimer formation and reduces the rates of phthalazine metabolism2022
- Author(s)
  Hinata Ueda, Katsuya Narumi, Ayako Furugen, Yoshitaka Saito, Masaki Kobayashi
- Journal Title
  
  Drug Metabolism & Disposition
  
  Volume: 50 Issue: 9 Pages: 1126-1131
- DOI
  10.1124/dmd.122.000902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07063
[Journal Article] Evaluation of possible pharmacokinetic interaction between methotrexate and proton pump inhibitors in rats2020
- Author(s)
  Ueda Hinata、Narumi Katsuya、Sato Yu、Furugen Ayako、Kobayashi Masaki、Iseki Ken
- Journal Title
  
  Pharmacological Reports
  
  Volume: 72 Issue: 5 Pages: 1426-1432
- DOI
  10.1007/s43440-020-00130-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07063
[Journal Article] Black tea extract and theaflavin derivatives affect the pharmacokinetics of rosuvastatin by modulating organic anion transporting polypeptide (OATP) 2B1 activity2019
- Author(s)
  Kondo Ayuko、Narumi Katsuya、Okuhara Keisuke、Takahashi Yuka、Furugen Ayako、Kobayashi Masaki、Iseki Ken
- Journal Title
  
  Biopharmaceutics & Drug Disposition
  
  Volume: 40 Issue: 8 Pages: 302-306
- DOI
  10.1002/bdd.2202
- NAID
  120006887718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14416
[Journal Article] Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP2019
- Author(s)
  Narumi Katsuya、Ohata Tsukika、Horiuchi Yuichi、Satoh Hiroshi、Furugen Ayako、Kobayashi Masaki、Iseki Ken
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 10 Pages: e0223892-e0223892
- DOI
  10.1371/journal.pone.0223892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14416
[Presentation] AOX1遺伝子の5’上流および3’非翻訳領域におけるSNP解析2024
- Author(s)
  林愛、鳴海克哉、上田一奈太、岡本敬介、古堅彩子、小林正紀
- Organizer
  第40回日本TDM学会・学術大会
- Data Source
  KAKENHI-PROJECT-23K06229
[Presentation] Effect of aldehyde oxidase inhibitors on azathioprine-induced hematologic and hepatic injury2023
- Author(s)
  Ueda Hinata, Narumi Katsuya, Furugen Ayako, Kobayashi Masaki
- Organizer
  日本薬学会第143年会 (PSJ/CSPS ジョイントシンポジウム)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07063
[Presentation] メトトレキサート誘発性肝障害におけるアルデヒドオキシダーゼの寄与―基礎および薬剤疫学的アプローチによる検証―2023
- Author(s)
  鳴海克哉、森山綾子、上田一奈太、淺野秀峰、古堅彩子、小林正紀
- Organizer
  医療薬学フォーラム2023 第31回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-23K06229
[Presentation] AOX1遺伝子のT755I多型は二量体形成および代謝活性を低下させる2022
- Author(s)
  上田一奈太、鳴海克哉、古堅彩子、小林正紀
- Organizer
  日本医療薬学会第5回フレッシャーズ・カンファランス
- Data Source
  KAKENHI-PROJECT-20K07063
[Presentation] Clinical importance of drug interaction between methotrexate and proton pump inhibitors and its potential mechanism2022
- Author(s)
  Katsuya Narumi
- Organizer
  The 7th Japan-Taiwan Joint Symposium For Pharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07063
[Presentation] メトトレキサート誘発性肝障害におけるaldehyde oxidase 1の関与2022
- Author(s)
  森山綾子、鳴海克哉、上田一奈太、古堅彩子、小林正紀
- Organizer
  第35回北海道薬物作用談話会
- Data Source
  KAKENHI-PROJECT-20K07063
[Presentation] メトトレキサートとプロトンポンプ阻害剤間の薬物相互作用に関する後方視的評価およびその相互作用機序の解析2021
- Author(s)
  鳴海克哉、上田一奈太、佐藤優、古堅彩子、井関健、小林正紀
- Organizer
  第31回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07063
[Presentation] リンゴポリフェノールによるOATP2B1を介した薬物相互作用の解析2020
- Author(s)
  高橋優花、鳴海克哉、古堅彩子、小林正紀、井関健
- Organizer
  日本薬学会北海道支部第147回例会
- Data Source
  KAKENHI-PROJECT-18K14416
[Presentation] dAMPの腸管吸収過程におけるCNT3およびCD73の協働的役割2020
- Author(s)
  大畑月香、鳴海克哉、佐藤浩志、古堅彩子、小林正紀、井関健
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K14416
[Presentation] メトトレキサート投与時におけるプロトンポンプ阻害剤のin vivoおよびin vitro薬物相互作用評価2020
- Author(s)
  上田一奈太、鳴海克哉、古堅彩子、小林正紀、井関健
- Organizer
  日本薬学会北海道支部第147回例会
- Data Source
  KAKENHI-PROJECT-20K07063
[Presentation] サケ白子に含まれるデオキシリボヌクレオチド類の消化吸収機構2019
- Author(s)
  大畑月香、鳴海克哉、佐藤浩志、古堅彩子、小林正紀、井関健
- Organizer
  日本薬学会北海道支部第146回例会
- Data Source
  KAKENHI-PROJECT-18K14416
[Presentation] 紅茶成分によるBCRP介在性薬物相互作用の解析2018
- Author(s)
  奥原圭祐、鳴海克哉、近藤安佑子、古堅彩子、小林正紀、井関健
- Organizer
  第32回北海道薬物作用談話会
- Data Source
  KAKENHI-PROJECT-18K14416

Narumi Katsuya 鳴海 克哉

Research Projects

Research Products

AOX1の新規SNP機能解析および副作用予測因子としての薬物動態学的意義の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pharmacogenetic analysis of pharmacokinetic factors related with methotrexate-induced toxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of complementary and alternative medicine for breast cancer based on kinetic characteristics of food componentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Comparative study on the occurrence of adverse effects in the concomitant use of azathioprine and aldehyde oxidase inhibitors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The rs35217482 (T755I) single-nucleotide polymorphism in aldehyde oxidase-1 attenuates protein dimer formation and reduces the rates of phthalazine metabolism2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of possible pharmacokinetic interaction between methotrexate and proton pump inhibitors in rats2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Black tea extract and theaflavin derivatives affect the pharmacokinetics of rosuvastatin by modulating organic anion transporting polypeptide (OATP) 2B1 activity2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] AOX1遺伝子の5’上流および3’非翻訳領域におけるSNP解析2024

Author(s)

Organizer

Data Source

[Presentation] Effect of aldehyde oxidase inhibitors on azathioprine-induced hematologic and hepatic injury2023

Author(s)

Organizer

Data Source

[Presentation] メトトレキサート誘発性肝障害におけるアルデヒドオキシダーゼの寄与―基礎および薬剤疫学的アプローチによる検証―2023

Author(s)

Organizer

Data Source

[Presentation] AOX1遺伝子のT755I多型は二量体形成および代謝活性を低下させる2022

Author(s)

Organizer

Data Source

[Presentation] Clinical importance of drug interaction between methotrexate and proton pump inhibitors and its potential mechanism2022

Author(s)

Organizer

Data Source

[Presentation] メトトレキサート誘発性肝障害におけるaldehyde oxidase 1の関与2022

Author(s)

Organizer

Data Source

[Presentation] メトトレキサートとプロトンポンプ阻害剤間の薬物相互作用に関する後方視的評価およびその相互作用機序の解析2021

Author(s)

Organizer

Data Source

[Presentation] リンゴポリフェノールによるOATP2B1を介した薬物相互作用の解析2020

Author(s)

Organizer

Data Source

[Presentation] dAMPの腸管吸収過程におけるCNT3およびCD73の協働的役割2020

Narumi Katsuya 鳴海克哉