YAMAMOTO MIZUKI 山本瑞生

Researcher Number	90750365
Other IDs	https://orcid.org/0000-0003-3731-1702
Affiliation (Current)	2024: 東京大学, 医科学研究所, 特任講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 東京大学, 医科学研究所, 特任講師 2018 – 2019: 東京大学, 医科学研究所, 助教 2016: 東京大学, 医科学研究所, 特任助教 2015: 東京大学, 医科学研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 49060:Virology-related / Pathological medical chemistry Except Principal Investigator Complex systems / Tumor biology
Keywords	Principal Investigator 上皮間葉転換 / 乳癌 / MET / EMT / TNBC / トリプルネガティブ乳癌 / membrane fusion / coronavirus infection / viral entry / metalloprotease … More / SARS-CoV-2 / Basal-like乳癌 / 細胞間相互作用 / 可塑性 / Breast cancer / CRISPR/Cas9 / CRISPR-Cas9 Screening / トリプルネガティブ乳癌(TNBC) / 上皮間葉転換(EMT) / Basal-like breast cancer / 乳腺上皮細胞 / 乳癌幹細胞 / 癌幹細胞 / 癌悪性化 … More Except Principal Investigator シグナル伝達 / 乳癌 / 数理シグナル / 乳がん / 白血病 / ユビキチン / 免疫 / 炎症 / 数理モデル / 癌 Less

Analysis of the metalloproteinase-dependent entry mechanism of SARS-CoV-2Principal Investigator
- Principal Investigator
  
  山本瑞生
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  The University of Tokyo
Genome-wide screening for EMT-MET plasticity in triple-negative breast cancerPrincipal Investigator
- Principal Investigator
  
  Yamamoto Mizuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Genome-wide screening for epithelial mesenchymal transition (EMT)-related genes in triple-negative breast cancerPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO MIZUKI
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Spatiotemporal regulation of Inflammation and immune signals by ubiquitination and its mathematical simulation
- Principal Investigator
  
  Inoue Jun-ichiro
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Analysis of mechanisms of breast cancer stem cells using mammary tumor model micePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO MIZUKI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Molecular mechanisms of maintenance of cancer stem cells in malignant breast cancers
- Principal Investigator
  
  Inoue Jun-ichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Tob negatively regulates NF-κB activation in breast cancer through its association with the TNF receptor complex.2023
- Author(s)
  Yamamoto Tadashi、Tokumasu Miho、Sato Atsuko、Ito-Kureha Taku、Yamamoto Mizuki、Ohmine Nao、Semba Kentaro、Inoue Jun-ichiro
- Journal Title
  
  Research Square
  
  Volume: -
- DOI
  10.21203/rs.3.rs-2714472/v1
- Open Access
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] Aberrant accumulation of NIK promotes tumor growth by dysregulating translation and post-translational modifications in breast cancer2023
- Author(s)
  Hayashi Yusuke、Nakayama Jun、Yamamoto Mizuki、Maekawa Masashi、Watanabe Shinya、Higashiyama Shigeki、Inoue Jun-ichiro、Yamamoto Yusuke、Semba Kentaro
- Journal Title
  
  Cancer Cell International
  
  Volume: 23 Issue: 1 Pages: 57-57
- DOI
  10.1186/s12935-023-02904-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02721, KAKENHI-PROJECT-20J01794, KAKENHI-PROJECT-20K07610, KAKENHI-PROJECT-21K15562
[Journal Article] Reactive oxygen species are associated with the inhibitory effect of<i>N</i>-(4-hydroxyphenyl)-retinamide on the entry of the severe acute respiratory syndrome-coronavirus 22023
- Author(s)
  Hayashi Yasuhiro、Huang Xuhao、Tanikawa Takashi、Tanigawa Kazunari、Yamamoto Mizuki、Gohda Jin、Inoue Jun-ichiro、Fukase Koichi、Kabayama Kazuya
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 5 Pages: 337-342
- DOI
  10.1093/jb/mvad020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19112, KAKENHI-PROJECT-22KJ2124, KAKENHI-PROJECT-20K07610
[Journal Article] Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-192022
- Author(s)
  Ogura Hideki、Gohda Jin、Lu Xiuyuan、Yamamoto Mizuki、Takesue Yoshio、Son Aoi、Doi Sadayuki、Matsushita Kazuyuki、Isobe Fumitaka、Fukuda Yoshihiro、Huang Tai-Ping、Ueno Takamasa、Mambo Naomi、Murakami Hiromoto、Kawaguchi Yasushi、Inoue Jun-ichiro、Shirai Kunihiro、Yamasaki Sho、Hirata Jun-Ichi、Ishido Satoshi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7063-7063
- DOI
  10.1038/s41467-022-34655-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0148, KAKENHI-PLANNED-22H05183, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20K07610, KAKENHI-PROJECT-23K24378
[Journal Article] SARS-CoV-2 Omicron spike H655Y mutation is responsible for enhancement of the endosomal entry pathway and reduction of cell surface entry pathways2022
- Author(s)
  Yamamoto Mizuki、Tomita Keiko、Hirayama Youko、Inoue Jun-ichiro、Kawaguchi Yasushi、Gohda Jin
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2022.03.21.485084
- Open Access
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein2022
- Author(s)
  Mizuki Yamamoto, Jun-Ichiro Inoue (corresponding author), 他9名
- Journal Title
  
  mBio
  
  Volume: 13(4) Issue: 4 Pages: 00519-22
- DOI
  10.1128/mbio.00519-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20K07610
[Journal Article] Discovery of new fusion inhibitor peptides against SARS-CoV-2 by targeting the Spike S2 subunit.2021
- Author(s)
  Kandeel, M., Yamamoto, M., Tani, H., Kobayashi, A., Gohda, J., Kawaguchi, Y., Park, B. K., Kwon, H.-J., Inoue, J. and Alkattan, A.
- Journal Title
  
  Biomol. Ther.
  
  Volume: in press Issue: 3 Pages: 282-289
- DOI
  10.4062/biomolther.2020.201
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-19K24679
[Journal Article] Metalloproteinase-dependent and TMPRSS2-independnt cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein2021
- Author(s)
  Yamamoto Mizuki、Gohda Jin、Kobayashi Ayako、Tomita Keiko、Hirayama Youko、Koshikawa Naohiko、Seiki Motoharu、Semba Kentaro、Akiyama Tetsu、Kawaguchi Yasushi、Inoue Jun-ichiro
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2021.12.14.472513
- Open Access
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] Aberrant accumulation of NIK promotes tumorigenicity by dysregulating post-translational modifications in breast cancer2021
- Author(s)
  Hayashi Yusuke、Nakayama Jun、Yamamoto Mizuki、Maekawa Masashi、Watanabe Shinya、Higashiyama Shigeki、Inoue Jun-ichiro、Yamamoto Yusuke、Semba Kentaro
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2021.08.27.457878
- Open Access
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] Discovery of new fusion inhibitor peptides against SARS-CoV-2 by targeting the spike S2 subunit.2021
- Author(s)
  Kandeel M, Yamamoto M, Tani H, Kobayashi A, Gohda J, Kawaguchi Y, Park BK, Kwon HJ, Inoue JI, Alkattan A.
- Journal Title
  
  Biomolecules & Therapeutics
  
  Volume: in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] Discovery of New Potent anti-MERS CoV Fusion Inhibitors2021
- Author(s)
  Kandeel Mahmoud、Yamamoto Mizuki、Park Byoung Kwon、Al-Taher Abdulla、Watanabe Aya、Gohda Jin、Kawaguchi Yasushi、Oh-hashi Kentaro、Kwon Hyung-Joo、Inoue Jun-ichiro
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 685161-685161
- DOI
  10.3389/fphar.2021.685161
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] TNF receptor-associated factor 6 (TRAF6) plays crucial roles in multiple biological systems through polyubiquitination-mediated NF-κB activation2021
- Author(s)
  Yamamoto, M., Gohda, J., Akiyama, T. and Inoue, J.
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 97 Issue: 4 Pages: 145-160
- DOI
  10.2183/pjab.97.009
- NAID
  130008023387
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2021-04-09
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-20K07610, KAKENHI-PROJECT-20H03441
[Journal Article] Cell-based membrane fusion assays with viral fusion proteins for identification of entry inhibitors2021
- Author(s)
  YAMAMOTO Mizuki、GOHDA Jin
- Journal Title
  
  Translational and Regulatory Sciences
  
  Volume: 3 Issue: 3 Pages: 72-76
- DOI
  10.33611/trs.2021-011
- NAID
  130008133970
- ISSN
  2434-4974
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner2020
- Author(s)
  Yamamoto Mizuki、Kiso Maki、Sakai-Tagawa Yuko、Iwatsuki-Horimoto Kiyoko、Imai Masaki、Takeda Makoto、Kinoshita Noriko、Ohmagari Norio、Gohda Jin、Semba Kentaro、Matsuda Zene、Kawaguchi Yasushi、Kawaoka Yoshihiro、Inoue Jun-ichiro
- Journal Title
  
  Viruses
  
  Volume: 12 Issue: 6 Pages: 629-629
- DOI
  10.3390/v12060629
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02665, KAKENHI-PROJECT-20K07610, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-19K24679
[Journal Article] The antimalarial compound atovaquone inhibits Zika and dengue virus infection by blocking E protein-mediated membrane fusion.2020
- Author(s)
  Yamamoto, M., Ichinohe, T., Watanabe, A., Kobayashi, A., Zhang, R., Song, J., Kawaguchi, Y., Matsuda, Z. and Inoue, J.
- Journal Title
  
  Viruses
  
  Volume: 12 Pages: 1475-1475
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Journal Article] The Antimalarial Compound Atovaquone Inhibits Zika and Dengue Virus Infection by Blocking E Protein-Mediated Membrane Fusion.2020
- Author(s)
  Yamamoto M, Ichinohe T, Watanabe A, Kobayashi A, Zhang R, Song J, Kawaguchi Y, Matsuda Z, Inoue JI.
- Journal Title
  
  Viruses
  
  Volume: 12 (12) Issue: 12 Pages: 1475-1475
- DOI
  10.3390/v12121475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07610
[Journal Article] Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers2020
- Author(s)
  Kandeel Mahmoud、Yamamoto Mizuki、Al-Taher Abdulla、Watanabe Aya、Oh-hashi Kentaro、Park Byoung Kwon、Kwon Hyung-Joo、Inoue Jun-ichiro、Al-Nazawi Mohammed
- Journal Title
  
  Biomolecules & Therapeutics
  
  Volume: Online first Issue: 4 Pages: 311-319
- DOI
  10.4062/biomolther.2019.202
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-20K07610, KAKENHI-ORGANIZER-16H06573
[Journal Article] Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series.2020
- Author(s)
  Doi, K,Ikeda,M.Hayase,N,Moriya,K.Maehara,H.Tagami,S.Fukushima,K.Misawa,N.Inoue,Y.Nakamura,H.Takai,D.Kurimoto,M.Tokunaga,K.Yamamoto,M.Hirayama,I.Horie,R.Endo,Y.Hiwatashi,K.Shikama,M.Jubishi,D.Kanno,Y.Okamoto,K.Harada,S.Okugawa,S.Miyazono,K.Seto,Y.Inoue,J.and Morimura,N.
- Journal Title
  
  Crit. Care
  
  Volume: 24 Issue: 1 Pages: 392-392
- DOI
  10.1186/s13054-020-03078-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575
[Journal Article] TRAF6 maintains mammary stem cells and promotes pregnancy-induced mammary epithelial cell expansion2019
- Author(s)
  Yamamoto Mizuki、Abe Chiho、Wakinaga Sakura、Sakane Kota、Yumiketa Yo、Taguchi Yuu、Matsumura Takayuki、Ishikawa Kosuke、Fujimoto Jiro、Semba Kentaro、Miyauchi Maki、Akiyama Taishin、Inoue Jun-ichiro
- Journal Title
  
  Communications Biology
  
  Volume: 2 Issue: 1 Pages: 292-292
- DOI
  10.1038/s42003-019-0547-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PROJECT-17K10999, KAKENHI-PROJECT-18K15235, KAKENHI-PUBLICLY-18H04989, KAKENHI-PROJECT-17H04038
[Journal Article] Cell-cell and virus-cell fusion assay-based analyses of alanine insertion mutants in the distal α9 portion of the JRFL gp41 subunit from HIV-1.2019
- Author(s)
  Mizuki Yamamoto, Qingling Du, Jiping Song, Hongyun Wang, Aya Watanabe, Yuetsu Tanaka, Yasushi Kawaguchi, Jun-ichiro Inoue and Zene Matsuda
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 294(14) Issue: 14 Pages: 5677-5687
- DOI
  10.1074/jbc.ra118.004579
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15235, KAKENHI-PLANNED-16H06575
[Journal Article] A method of producing genetically manipulated mouse mammary gland.2019
- Author(s)
  Tagaya H., Ishikawa K., Hosokawa Y., Kobayashi S., Ueoka Y., Shimada M., Ohashi Y., Mikami H., Yamamoto M., Ihara T., Kumazawa K., Sugihara K., Goshima N., Watanabe S., Semba K.
- Journal Title
  
  Breast Cancer Res.
  
  Volume: 21, 1 Issue: 1 Pages: 1-12
- DOI
  10.1186/s13058-018-1086-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15235, KAKENHI-PROJECT-16H06276
[Journal Article] High-Throughput Screening for Linear Ubiquitin Chain Assembly Complex (LUBAC) Selective Inhibitors Using Homogenous Time-Resolved Fluorescence (HTRF)-Based Assay System2018
- Author(s)
  Katsuya Ken、Hori Yuji、Oikawa Daisuke、Yamamoto Tomohisa、Umetani Kayo、Urashima Toshiki、Kinoshita Tomomi、Ayukawa Kumiko、Tokunaga Fuminori、Tamaru Masahiro
- Journal Title
  
  SLAS DISCOVERY: Advancing Life Sciences R&D
  
  Volume: 23 Issue: 10 Pages: 1018-1029
- DOI
  10.1177/2472555218793066
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06967
[Journal Article] Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination2018
- Author(s)
  Ogawa M, Matsuda R, Takada N, Tomokiyo M, Yamamoto S, Shizukusihi S, Yamaji T, Yoshikawa Y, Yoshida M, Tanida I, Koike M, Murai M, Morita H, Takeyama H, Ryo A, Guan JL, Yamamoto M, Inoue JI, Yanagawa T, Fukuda M, Kawabe H, Ohnishi M
- Journal Title
  
  Cellular Microbiology
  
  Volume: e12846 Issue: 8
- DOI
  10.1111/cmi.12846
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08798, KAKENHI-PROJECT-16K08800, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-15K12749, KAKENHI-PROJECT-17K19888, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-15K21769, KAKENHI-PROJECT-17K08841, KAKENHI-PUBLICLY-17H05682
[Journal Article] In-frame Val 216 -Ser 217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response2018
- Author(s)
  Hattori Mai、Ishikawa Osamu、Oikawa Daisuke、Amano Hiroo、Yasuda Masahito、Kaira Kyoichi、Ishida-Yamamoto Akemi、Nakano Hajime、Sawamura Daisuke、Terawaki Shin-ichi、Wakamatsu Kaori、Tokunaga Fuminori、Shimizu Akira
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 91 Issue: 1 Pages: 35-42
- DOI
  10.1016/j.jdermsci.2018.03.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07301, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K07262, KAKENHI-PROJECT-18K06967
[Journal Article] Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.2018
- Author(s)
  Johmura Y, Maeda I, Suzuki N, Wu W, Goda A,Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T Akiyama F, Maruyama R, Inoue JI, Fukukawa Y, Ohta T, Nkanishi M.
- Journal Title
  
  J Clin Invest.
  
  Volume: 128 Issue: 12 Pages: 5603-5619
- DOI
  10.1172/jci121679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-18K15235, KAKENHI-PLANNED-16H06575, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-17K18336, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-17K07214
[Journal Article] In-frame Val216-Ser217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response.2018
- Author(s)
  Hattori M, Ishikawa O, Oikawa D, Amano H, Yasuda M, Kaira K, Ishida-Yamamoto A, Nakano H, Sawamura D, Terawaki SI, Wakamatsu K, Tokunaga F, Shimizu A
- Journal Title
  
  J. Dermatol. Sci.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06575
[Journal Article] Six-helix bundle completion in the distal C-terminal heptad repeat region of gp41 is required for efficient human immunodeficiency virus type 1 infection2018
- Author(s)
  Liu, D., Wang, H., Yamamoto, M., Song, J., Zhang, R., Du, Q., Kawaguchi, Y., Inoue, J. and Matsuda, Z.
- Journal Title
  
  Retrovirology
  
  Volume: 15 Issue: 1 Pages: 1-11
- DOI
  10.1186/s12977-018-0410-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18K15235
[Journal Article] Mechanistic insight into the repigmentation of piebaldism: functional characterization of a mutant KIT in melanocyte regeneration.2018
- Author(s)
  Hattori M, Oikawa D, Amano H, Yasuda M, Kaira K, Ishida-Yamamoto A, Nakano H, Sawamura D, Terawaki S, Wakamatsu K, Tokunaga F, Ishikawa O, Shimizu A.
- Journal Title
  
  J. Dermatol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06575
[Journal Article] Reduced SHARPIN and LUBAC formation may contribute to CCl4- or acetaminophen-induced liver cirrhosis in mice.2017
- Author(s)
  Yamamotoya T, Nakatsu Y, Matsunaga Y, Fukushima T, Yamazaki H, Kaneko S, Fujishiro M, Kikuchi T, Kushiyama A, Tokunaga F, Asano T, and Sakoda H.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 18 Issue: 2 Pages: 326-326
- DOI
  10.3390/ijms18020326
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-15H06427, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-16K15210, KAKENHI-PROJECT-16K09784
[Journal Article] ER stress in the pathogenesis of pretibial dystrophic epidermolysis bullosa.2017
- Author(s)
  Hattori M, Shimuzu A, Oikawa D, Kamei K, Kaira K, Ishida-Yamamoto A, Nakano H, Sawamura D, Tokunaga F, and Ishikawa O.
- Journal Title
  
  Br. J. Dermatol.
  
  Volume: 印刷中 Issue: 4 Pages: e92-e93
- DOI
  10.1111/bjd.15342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-16K15210, KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-15K09739
[Journal Article] Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer.2017
- Author(s)
  Yamamoto, M., Sakane, K., Tominaga, K., Gotoh, N., Niwa, T., Kikuchi, Y., Tada, K., Goshima, N., Semba, K. and Inoue, J.
- Journal Title
  
  Cancer Sci
  
  Volume: 印刷中 Issue: 6 Pages: 1210-1222
- DOI
  10.1111/cas.13246
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290036, KAKENHI-PROJECT-15K21438, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-16J40231
[Journal Article] Identification of nafamostat as a potent inhibitor of Middle East respiratory syndrome (MERS) corona virus S-mediated membrane fusion using the split protein-based cell-cell fusion assay2016
- Author(s)
  Yamamoto, M., Mastsuyama, S., Li, X., Takeda, M., Kawaguchi, Y., Inoue, J.* and Matsuda, Z.
- Journal Title
  
  Antimicrob. Agents Chemother.
  
  Volume: 60（11） Issue: 11 Pages: 6532-6539
- DOI
  10.1128/aac.01043-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575
[Journal Article] Tropomodulin 1 expression driven by NF-kB enhances breast cancer growth.2015
- Author(s)
  Ito-Kureha, T., Koshikawa, N., Yamamoto, M., Semba, K., Yamaguchi, N., Yamamoto, T., Seiki, M. and Inoue, J.
- Journal Title
  
  Cancer Res
  
  Volume: 75 Issue: 1 Pages: 62-72
- DOI
  10.1158/0008-5472.can-13-3455
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22117001, KAKENHI-PUBLICLY-25121734, KAKENHI-PROJECT-25460356, KAKENHI-PROJECT-26290036, KAKENHI-PROJECT-25462471
[Journal Article] Visualization of RelB expression and activation at the single-cell level during dendritic cell maturation in Relb-Venus knock-in mice2015
- Author(s)
  Takao Seki, Mami Yamamoto, Yuu Taguchi, Maki Miyauchi, Noritaka Yamaguchi, Jin Gohda, Taishin Akiyama, Jun-ichiro Inoue
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 158 Pages: 485-495
- DOI
  10.1093/jb/mvv064
- NAID
  40020683863
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19986, KAKENHI-PLANNED-22117002, KAKENHI-PUBLICLY-15H01150, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-22117001, KAKENHI-PROJECT-25460356, KAKENHI-PROJECT-26670234, KAKENHI-PROJECT-26290036
[Presentation] 、ウイルスエンベロープタンパク質依存性膜融合の定量化のための細胞融合アッセイの確立Establishment of a cell fusion assay for the quantification of viral envelope protein-dependent membrane fusion.2021
- Author(s)
  山本瑞生, 井上純一郎, 川口寧, 合田仁
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] Cell-based membrane fusion assay for flavivirus envelope proteins.2021
- Author(s)
  Mizuki Yamamoto, Jun-ichiro Inoue, Yasushi Kawaguchi, Jin Gohda
- Organizer
  The 62nd Annual Meeting for the Japanese Society of Tropical Medicine
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] Cell-based high throughput membrane fusion assay for SARS-CoV-2 S protein.2021
- Author(s)
  Mizuki Yamamoto, Jun-ichiro Inoue, Yasushi Kawaguchi and Jin Gohda.
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] CRISPR/Cas9システムを用いたトリプルネガティブ乳癌におけるEMT/MET可塑性制御機構の解析 The CRISPR/Cas9-mediated gene knockout screening to analyze EMT-MET plasticity in triple-negative breast cancer2021
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Jin Gohda, Yoichi Furukawa and Jun-ichiro Inoue.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] 新型コロナウイルスのエンベロープタンパク質を用いた細胞融合アッセイの確立 Cell-based high throughput membrane fusion assay for SARS-CoV-2.2021
- Author(s)
  山本瑞生, 井上純一郎, 川口寧, 合田仁
- Organizer
  2021年度若手支援技術講習会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] 、ウイルスエンベロープタンパク質依存性膜融合の定量のための細胞融合アッセイの確立2021
- Author(s)
  山本瑞生
- Organizer
  第21回Pharmaco-Hematologyシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] SARS-CoV-2 S依存的な細胞融合アッセイによる抗血液凝固剤ナファモスタットの抗ウイルス感染作用の発見　The anticoagulant Nafamostat potently inhibits SARS-CoV-2 S protein-mediated fusion in a cell fusion assay system and viral infection in vitro in a cell-type-dependent manner.2020
- Author(s)
  Mizuki Yamamoto, Jun-ichiro Inoue, Yasushi Kawaguchi, Jin Gohda.
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] CRISPR/Cas9システムを用いたトリプルネガティブ乳癌におけるEMT/MET可塑性制御機構の解析2020
- Author(s)
  山本瑞生、山口貴世志、古川洋一、井上純一郎
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] The CRISPR/Cas9-mediated gene knockout screening to analyze EMT-MET plasticity in triple-negative breast cancer2020
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Jin Gohda, Yoichi Furukawa and Jun-ichiro Inoue
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07610
[Presentation] Intratumoral bidirectional transitions between epithelial & mesenvhymal cells in triple-negative breast cancer2020
- Author(s)
  Jun-ichiro Inoue. Mizuki Yamamoto
- Organizer
  Establishing International Research Network of Mathematical Oncology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assy System and Viral Infection in vitro in a Cell-Type-Dependent Manner2020
- Author(s)
  Mizuki Yamamoto, Jun-ichiro Inoue, Yasushi Kawaguchi and Jin Gohda
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer2019
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Yoichi Furukawa and Jun-ichiro Inoue
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] Intratumoral bidirectional transitions beyween epithelial and mesenchymal cells in triple-negative breast cancer2019
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] The CRISPR-Cas9-mediated gene knockout system to identify tumor suppressor genes in basal-like breast cancer mouse model2019
- Author(s)
  Chiho Abe, Mizuki Yamamoto, Jun-ichiro Inoue
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] Establisyment of quantitative membrane fusion assay for Dengue virus2019
- Author(s)
  藤波祐丞、山本瑞生、渡辺亜矢、井上純一郎
- Organizer
  先端モデル動物支援プラットフォーム成果発表会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Cell-based membrane fusion assay for flavivirus envelope proteins2019
- Author(s)
  Mizuki yamamoto, Takeshi Ichinohe, Aya Watanabe, Yusuke Fujinami, Yasushi Kawaguchi, Zene Matsuda, Jun-ichiro Inoue
- Organizer
  Asian-African Research Forum on Emerging and Reemerging Infections 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] The CRISPR/Cas9-mediated gene knockout screening to analyze EMT-MET plasticity in triple-negative breast cancer2019
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Yoichi Furukawa and Jun-ichiro Inoue
- Organizer
  Cell symposia: Hallmarks of Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] The CRISPR/Cas9-meditated gene knpckout screening to analyze EMT-MET plasticity in triple-negative breast cancer2019
- Author(s)
  M.Yamamoto, K.Yamaguchi, Y.Furukawa, J.Inoue
- Organizer
  TEMTIA IX
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer2019
- Author(s)
  Mizuki Yamamoto, Jun-ichiro Inoue
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] Mechanistic analysis of small molecules that inhibit flavivirus E protein-mediated membrane fusion2019
- Author(s)
  Yusuke Fujinami, Mizuki Yamamoto, Aya Watanabe, Yasushi Kawaguchi, Zene Matsuda, Jun-ichiro Inoue
- Organizer
  Asian-African Research Forum on Emerging and Reemerging Infections 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] The CRISPR-Cas9 mediated gene knockout system to identify tumor suppressor genes in basal-like breast cancer mouse model2019
- Author(s)
  阿部智帆、山本瑞生、井上純一郎
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] The CRISPR/Cas9-mediated gene knockout screening to analyze EMT-MET plasticity in triple-negative breast cancer2019
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Yoichi Furukawa and Jun-ichiro Inoue
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] CRISPR/Cas9システムを用いたトリプルネガティブ乳癌におけるEMT/MET可塑性制御機構の解析2019
- Author(s)
  山本瑞生、山口貴世志、古川洋一、井上純一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Genome wide screening for regulator of epithelial to mesenchymal transition (EMT) in triple-negative breast cancer2019
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Yoichi Furukawa and Jun-ichiro Inoue
- Organizer
  The 9th EMT International Association Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] CRISPR/Cas9システムを用いたトリプルネガティブ乳癌におけるEMT/MET可塑性制御機構の解析2019
- Author(s)
  山本瑞生、山口貴世志、古川洋一、井上純一郎
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] フラビウイルスエンベロープタンパクのウイルスフリー膜融合アッセイ2019
- Author(s)
  山本瑞生、一戸猛志、渡邉亜矢、藤波祐丞、川口寧、松田善衛、井上純一郎
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Critical roles of FRS2beta for creating the cytokine-rich precancerous microenvironment for mammary tumorigenesis2019
- Author(s)
  Tatsunori Nishimura, Natsuoko Kimura, Takahiko Murayama, Yukino Machida, Daisuke Iejima, Reiko Sakamoto, Mizuki Yamamoto, Naoki Itano, Yusuke Inoue, Masataka Ito, Nobuyuki Yoshida, Junichiro Inoue, Kouichi Akashi, Hideyuki Saya, Koji Fujita, Masahiko Kuroda, Issay Kitabayashi, Arinobu Tojo, Noriko Gotoh
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] フラビウイルスEタンパク質依存性膜融合に対する低分子阻害剤の作用機構解析2019
- Author(s)
  藤波祐丞、山本瑞生、渡邉亜矢、川口寧、松田善衛、井上純一郎
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Mechanistic analysis of small molecules that inhibit flavivirus E protein-mediated membrane fusion2019
- Author(s)
  Yusuke Fujinami, Mizuki Yamamoto, Aya Watanabe, Yasushi Kawaguchi, Zene Matsuda, Jun-ichiro Inoue
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Basal-like乳癌における自発的上皮間葉転換（EMT)とMETの機構解析2018
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  先端モデル動物支援プラットフォーム・若手支援技術講習会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Basal-like乳癌モデルマウスにおける、ゲノム編集技術CRISPR-Cas9を利用した癌抑制遺伝子評価系の確立2018
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer2018
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] The CRISPR-Cas9 mediated gene knockout system to identify tumor suppressor genes in basal-like breast cancer mouse model2018
- Author(s)
  阿部智帆、山本瑞生、井上純一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer2018
- Author(s)
  山本瑞生
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] TRAF6は乳腺上皮幹細胞の維持および乳腺上皮細胞の増殖と生存の促進によって妊娠期の乳腺発達を促進する2018
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] ゲノム編集技術CRISPR/Cas9システムを利用したBasal-like乳癌モデルマウスの開発2018
- Author(s)
  阿部智帆、山本瑞生、井上純一郎
- Organizer
  先端モデル動物支援プラットフォーム　成果発表会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] トリプルネガティブ乳癌におけるEMT/MET相互転換機構の解析2018
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第77回日本癌学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] The CRISPR-Cas9-mediated gene knockout system to identify tumor suppressor genes in basal-like breast cancer mouse model2018
- Author(s)
  阿部知帆、山本瑞生、井上純一郎
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] Basal-like乳癌モデルマウスにおけるゲノム編集技術CRISPR-Cas9を利用した癌抑制遺伝子評価系の確立2018
- Author(s)
  阿部智帆、山本瑞生、井上純一郎
- Organizer
  先端モデル動物支援プラットフォーム・若手支援技術講習会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Basal-like乳癌モデルマウスにおけるゲノム編集技術CRISPR-Cas9を利用した癌抑制遺伝子評価系の確立2018
- Author(s)
  阿部知帆、山本瑞生、井上純一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15235
[Presentation] TRAF6は乳腺上皮細胞の維持および乳腺上皮細胞の細胞死抑制によって妊娠期の乳腺発達を促進する2017
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  先端モデル動物支援プラットフォーム
- Place of Presentation
  琵琶湖ホテル
- Year and Date
  2017-02-06
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] TRAF6は乳腺上皮細胞の維持および乳腺上皮細胞の細胞死抑制によって妊娠期の乳腺発達を促進する2017
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  先端モデル動物支援プラットフォーム
- Place of Presentation
  琵琶湖ホテル
- Year and Date
  2017-02-06
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breastnancer2017
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  Adovances in Breast Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Basal-like乳癌における腫瘍内上皮間葉転換機構の解析2017
- Author(s)
  山本瑞生、後藤典子、井上純一郎
- Organizer
  金沢大学がん進展制御研究所　共同利用・共同研究拠点シンポジウム
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] トリプルネガティブ乳癌における上皮‐間葉‐腫瘍内双方向転換の制御機構2017
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Basal-like乳がんモデルマウスにおけるCRISPR/Cas9システムを利用したガン抑制遺伝子の探索2016
- Author(s)
  坂根康太、山本瑞生、井上純一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] TRAF6は乳腺上皮細胞の維持および乳腺上皮細胞の細胞死抑制によって妊娠期の乳腺発達を促進する2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] 乳腺発達と乳がん悪性化における転写因子NF-κBの役割の相違2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] TRAF6は乳腺上皮細胞の維持および乳腺上皮細胞の細胞死抑制によって妊娠期の乳腺発達を促進する2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] Differential roles of NF-kB activation in mammary gland development and breast cancer malignancy2016
- Author(s)
  Mizuki Yamamoto, Jun-ichiro Inoue
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K21438
[Presentation] TRAF6は乳腺幹細胞の維持および乳腺上皮細胞の細胞死抑制によって妊娠期の乳腺発達を促進する2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K21438
[Presentation] 乳がんを標的とした新規NF-kappaB阻害剤の探索2016
- Author(s)
  真鍋英里香、上松篤史、城戸康希、竹田浩之、高橋宏隆、山本瑞生、井上純一郎、澤崎達也
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] TRAF6 regulates pregnancy-induced mammary gland development and maintenance of epithelial stem cells2016
- Author(s)
  Mizuki Yamamoto, Jun-ichiro Inoue
- Organizer
  KEYSTONE SYMPOSIA
- Place of Presentation
  Breckenridge, Colorado (USA)
- Year and Date
  2016-03-06
- Data Source
  KAKENHI-PROJECT-15K21438
[Presentation] 乳腺発達と乳がん悪性化における転写因子NF-κBの役割の相違2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] TRAF6は乳腺上皮細胞の維持および乳腺上皮細胞の細胞死抑制によって妊娠期の乳腺発達を促進する2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  先端モデル動物支援　若手技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] Basal-like乳がんモデルマウスにおけるCRISPR/Cas9システムを利用したガン抑制遺伝子の探索2016
- Author(s)
  坂根康太、山本瑞生、井上純一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] TRAF6 regulates pregnancy-induced mammary gland development and maintenance of epithelial stem cells2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  Keystone symposia Stem Cells and Cancer (C1)
- Place of Presentation
  Beaver Run Resort（米国　コロラド州）
- Year and Date
  2016-03-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] 乳がんを標的とした新規NF-kappaB阻害剤の探索2016
- Author(s)
  真鍋英里香、上松篤史、城戸康希、竹田浩之、高橋宏隆、山本瑞生、井上純一郎、澤崎達也
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] .Visualization of RelB expression and activation at the single-cell level during dendritic cell maturation in Relb-Venus knock-in mice2016
- Author(s)
  関崇生、山本真実、田口祐、宮内真紀、秋山伸子、山口憲孝、合田仁、秋山泰身、井上純一郎
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Whistler Conference Centre（カナダ　バンクーバー）
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] TRAF6は乳腺上皮細胞の維持および乳腺上皮細胞の細胞死抑制によって妊娠期の乳腺発達を促進する2016
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  先端モデル動物支援　若手技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PLANNED-16H06575
[Presentation] 乳癌における細胞間相互作用による上皮感葉転換の制御2015
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際センター（愛知県名古屋市）
- Year and Date
  2015-11-11
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] 妊娠期の乳癌成熟および幹細胞維持におけるTRAF6の役割2015
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26290036
[Presentation] Non-Cell-Autonomous Regulation of Epithelial-Mesenchymal Transition in Breast Cancer2015
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  日本癌学会学術総会
- Place of Presentation
  NAGOYA CONGRESS CENTER(愛知県・名古屋)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K21438
[Presentation] 妊娠期の乳腺成熟および幹細胞維持におけるTRAF6の役割2015
- Author(s)
  山本瑞生、井上純一郎
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県・神戸)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K21438

1. Inoue Jun-ichiro (70176428)

# of Collaborated Projects: 2 results

# of Collaborated Products: 50 results
2. 徳永文稔 (00212069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. YAMAMOTO Shouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. WU Wenwen

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. INOUE Ken-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. KABAYAMA Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 上野貴将

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 山本雄介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 竹田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 若松馨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 田口祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAMOTO MIZUKI 山本 瑞生

Research Projects

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Analysis of the metalloproteinase-dependent entry mechanism of SARS-CoV-2Principal Investigator

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Genome-wide screening for EMT-MET plasticity in triple-negative breast cancerPrincipal Investigator

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Genome-wide screening for epithelial mesenchymal transition (EMT)-related genes in triple-negative breast cancerPrincipal Investigator

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Spatiotemporal regulation of Inflammation and immune signals by ubiquitination and its mathematical simulation

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Analysis of mechanisms of breast cancer stem cells using mammary tumor model micePrincipal Investigator

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Molecular mechanisms of maintenance of cancer stem cells in malignant breast cancers

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[Journal Article] Tob negatively regulates NF-κB activation in breast cancer through its association with the TNF receptor complex.2023

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[Journal Article] Aberrant accumulation of NIK promotes tumor growth by dysregulating translation and post-translational modifications in breast cancer2023

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[Journal Article] Reactive oxygen species are associated with the inhibitory effect of<i>N</i>-(4-hydroxyphenyl)-retinamide on the entry of the severe acute respiratory syndrome-coronavirus 22023

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[Journal Article] Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-192022

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[Journal Article] SARS-CoV-2 Omicron spike H655Y mutation is responsible for enhancement of the endosomal entry pathway and reduction of cell surface entry pathways2022

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[Journal Article] Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein2022

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[Journal Article] Discovery of new fusion inhibitor peptides against SARS-CoV-2 by targeting the Spike S2 subunit.2021

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[Journal Article] Metalloproteinase-dependent and TMPRSS2-independnt cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein2021

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YAMAMOTO MIZUKI 山本瑞生