Noshiro Daisuke 能代大輔

… Alternative Names

NOSHIRO Daisuke 能代大輔

Less

Researcher Number	90751107
Other IDs
Affiliation (Current)	2025: 北海道大学, 遺伝子病制御研究所, 助教
Affiliation (based on the past Project Information) *help	2023: 北海道大学, 遺伝子病制御研究所, 助教 2022: 北海道大学, 遺伝子病制御研究所, 特任助教 2018 – 2021: 公益財団法人微生物化学研究会, 微生物化学研究所, 博士研究員 2017: 金沢大学, バイオAFM先端研究センター, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy
Keywords	Principal Investigator 高速原子間力顕微鏡 / 液―液相分離 / オートファジー / 天然変性領域 / ポリユビキチン / 液ー液相分離 / リン酸化 / 天然変性タンパク質 / 液滴 / 酵素 … More / 生体分子 / 一分子生物学 / 生物物理 / ビオチン / タマビジン２ / 高速AFM / 二次元結晶 / タマビジン2 / 観察基板 / ATPase / ヘリカーゼ Less

相分離液滴のオートファジー分解効率を規定する構造基盤の解明Principal Investigator
- Principal Investigator
  
  能代大輔
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Hokkaido University
High-speed AFM observation of autophagosome formation sites formed by liquid-liquid phase separationPrincipal Investigator
- Principal Investigator
  
  Noshiro Daisuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Hokkaido University
  Microbial Chemistry Research Foundation
High-speed AFM observation of archaeal MCM protein complexesPrincipal Investigator
- Principal Investigator
  
  NOSHIRO Daisuke
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Microbial Chemistry Research Foundation
  Kanazawa University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] 実験医学2021年8月号2021
- Author(s)
  能代　大輔、野田　展生
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19K16344
[Journal Article] A glutamine sensor that directly activates TORC12021
- Author(s)
  Tanigawa Mirai、Yamamoto Katsuyoshi、Nagatoishi Satoru、Nagata Koji、Noshiro Daisuke、Noda Nobuo N.、Tsumoto Kouhei、Maeda Tatsuya
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1093-1093
- DOI
  10.1038/s42003-021-02625-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-18H02151, KAKENHI-PROJECT-20H03251, KAKENHI-PROJECT-20K06555, KAKENHI-PROJECT-19K16344, KAKENHI-PROJECT-20H02531
[Journal Article] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2021
- Author(s)
  Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 16-16
- DOI
  10.1038/s41467-020-20185-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07276, KAKENHI-PROJECT-20K06549, KAKENHI-PROJECT-20K06644, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-20H03415, KAKENHI-PROJECT-16H06276
[Journal Article] Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy2020
- Author(s)
  Kodera Noriyuki、Noshiro Daisuke、Dora Sujit K.、Mori Tetsuya、Habchi Johnny、Blocquel David、Gruet Antoine、Dosnon Marion、Salladini Edoardo、Bignon Christophe、Fujioka Yuko、Oda Takashi、Noda Nobuo N.、Sato Mamoru、Lotti Marina、Mizuguchi Mineyuki、Longhi Sonia、Ando Toshio
- Journal Title
  
  Nature Nanotechnology
  
  Volume: 16 Issue: 2 Pages: 181-189
- DOI
  10.1038/s41565-020-00798-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06527, KAKENHI-PROJECT-20K06567, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-18H02391
[Journal Article] 柔らかい構造の可視化―LLPSと膜動態を例に2020
- Author(s)
  能代　大輔、野田　展生
- Journal Title
  
  実験医学
  
  Volume: 38 Pages: 84-89
- Data Source
  KAKENHI-PROJECT-19K16344
[Journal Article] Phase separation organizes the site of autophagosome formation2020
- Author(s)
  Fujioka Yuko、Alam Jahangir Md.、Noshiro Daisuke、Mouri Kazunari、Ando Toshio、Okada Yasushi、May Alexander I.、Knorr Roland L.、Suzuki Kuninori、Ohsumi Yoshinori、Noda Nobuo N.
- Journal Title
  
  Nature
  
  Volume: 578 Issue: 7794 Pages: 301-305
- DOI
  10.1038/s41586-020-1977-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22520, KAKENHI-PROJECT-19K16344, KAKENHI-PUBLICLY-18H04751, KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-18H03989, KAKENHI-PROJECT-19H03394, KAKENHI-PROJECT-17K07319, KAKENHI-PROJECT-16H06280, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05795, KAKENHI-PROJECT-16H06375, KAKENHI-PLANNED-19H05708
[Journal Article] Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion2020
- Author(s)
  Matoba Kazuaki、Kotani Tetsuya、Tsutsumi Akihisa、Tsuji Takuma、Mori Takaharu、Noshiro Daisuke、Sugita Yuji、Nomura Norimichi、Iwata So、Ohsumi Yoshinori、Fujimoto Toyoshi、Nakatogawa Hitoshi、Kikkawa Masahide、Noda Nobuo N.
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 27 Issue: 12 Pages: 1185-1193
- DOI
  10.1038/s41594-020-00518-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06532, KAKENHI-PROJECT-19K07265, KAKENHI-PROJECT-19K16071, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H05339, KAKENHI-PROJECT-16H06375, KAKENHI-PROJECT-19H05645, KAKENHI-PROJECT-18H03989, KAKENHI-PROJECT-18H04023, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06097, KAKENHI-PLANNED-19H05708, KAKENHI-PLANNED-19H05777
[Journal Article] Liquidity Is a Critical Determinant for Selective Autophagy of Protein Condensates2020
- Author(s)
  Yamasaki Akinori、Alam Jahangir Md.、Noshiro Daisuke、Hirata Eri、Fujioka Yuko、Suzuki Kuninori、Ohsumi Yoshinori、Noda Nobuo N.
- Journal Title
  
  Molecular Cell
  
  Volume: 77 Issue: 6 Pages: 1163-1175
- DOI
  10.1016/j.molcel.2019.12.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-18H03989, KAKENHI-PROJECT-18J13429, KAKENHI-PROJECT-17K07319, KAKENHI-PROJECT-17K18339, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-16H06375, KAKENHI-PLANNED-19H05708
[Journal Article] Substrate protein dependence of GroEL-GroES interaction cycle revealed by high-speed AFM imaging2018
- Author(s)
  D. Noshiro and T. Ando
- Journal Title
  
  Philosophical Transactions B
  
  Volume: 印刷中 Issue: 1749 Pages: 20170180-20170180
- DOI
  10.1098/rstb.2017.0180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-17K15433
[Presentation] Observation of the structures and dynamics of the autophagy-related proteins using high-speed AFM2023
- Author(s)
  能代大輔
- Organizer
  第10回IGM研究会
- Data Source
  KAKENHI-PROJECT-23K06065
[Presentation] 高速原子間力顕微鏡を用いたオートファジー関連タンパク質のイメージングの試み2023
- Author(s)
  能代大輔, 藤岡優子, 野田展生
- Organizer
  第9回北大部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-23K06065
[Presentation] ULK1/2-mediated p62-phosphorylation at Ser349 is physiologically important for NRF2 activation2022
- Author(s)
  Ryo Ikeda, Yoshinobu Ichimura, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Tomoko Funakoshi, Satoko Komatsu-Hirota, Shun Kageyama, Ritsuko Arai, Manabu Abe, Kenji Sakimura, Arata Horii, Satoshi Waguri
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] ULK1キナーゼによるp62の液-液相分離制御2022
- Author(s)
  池田良, 一村義信, 森下英晃, 能代大輔, 船越智子, 小松聡子, 蔭山俊, 野田展生, 小松雅明
- Organizer
  第30回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] UFM1システム:Alphafold2構造予測からわかったUFM1システムの作動原理2022
- Author(s)
  石村亮輔, 能代大輔, 植村武文, 和栗聡, 野田展生, 小松雅明
- Organizer
  第30回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] カーゴの流動性が選択的オートファジーでの分解を左右する2021
- Author(s)
  山崎章徳、Jahangir MD. Alam、能代大輔、平田恵理、藤岡優子、Alexander I. May、鈴木邦律、大隅良典、野田展生
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] p62顆粒はオートファゴソーム形成とストレス応答の足場として働く機能的液滴である2021
- Author(s)
  蔭山俊、Sigurdur Gudmundsson、曽友深、一村義信、田村直輝、數野彩子、上野隆、三浦芳樹、能代大輔、阿部学、水島恒裕、三浦信明、奥田修二郎、本橋ほづみ、Jin-A Lee、﨑村建司、大江知之、野田展生、和栗聡、Eeva-Liisa Eskelinen、小松雅明
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] 高速原子間力顕微鏡によるオートファジー関連タンパク質の動態観察2021
- Author(s)
  能代　大輔
- Organizer
  日本顕微鏡学会学際的顕微研究領域若手研究部会2021年度WEBシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] 高速原子間力顕微鏡を用いたオートファジー関連タンパク質のイメージング2020
- Author(s)
  能代大輔、藤岡優子、鈴木浩典、安藤敏夫、野田展生
- Organizer
  第13回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] 高速AFMを用いた選択的オートファジー関連タンパク質Atg11の観察2019
- Author(s)
  能代　大輔、鈴木　浩典、藤岡　優子、野田　展生
- Organizer
  第１２回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] Dual observation of autophagy-related proteins by combined high-speed AFM and fluorescence microscope2019
- Author(s)
  Daisuke Noshiro, Hironori Suzuki, Yuko Fujioka, Nobuo N. Noda
- Organizer
  第３回オートファジー討論会
- Data Source
  KAKENHI-PROJECT-19K16344
[Presentation] 高速AFMによるAtg17-Atg29-Atg31のS字構造とAtg13-Atg17-Atg29-Atg31複合体により形成される液滴の観察2018
- Author(s)
  能代大輔、藤岡優子、安藤敏夫、野田展生
- Organizer
  第11回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-17K15433
[Presentation] オートファジーの足場タンパク質Atg17-Atg29-Atg31複合体の高速AFM観察2018
- Author(s)
  能代大輔、藤岡優子、野田展生、安藤敏夫
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K15433
[Presentation] Two-dimensional crystals of tamavidin 2 for a quick and easy method of immobilization of biotinylated biomolecules2017
- Author(s)
  能代大輔、古寺哲幸、安藤敏夫
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K15433
[Presentation] Two-dimensional crystals of tamavidin 2 on mica surface and their application2017
- Author(s)
  Daisuke Noshiro, Noriyuki Kodera, Toshio Ando
- Organizer
  International Symposium on Atomic Force Microscopy at Solid-Liquid Interfaces
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15433

1. NODA Nobuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 小田隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 曽友深

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 毛利一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 安藤敏夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 森貴治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Noshiro Daisuke 能代 大輔

NOSHIRO Daisuke 能代 大輔

Research Projects

Research Products

Co-Researchers

相分離液滴のオートファジー分解効率を規定する構造基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

High-speed AFM observation of autophagosome formation sites formed by liquid-liquid phase separationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

High-speed AFM observation of archaeal MCM protein complexesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学2021年8月号2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] A glutamine sensor that directly activates TORC12021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 柔らかい構造の可視化―LLPSと膜動態を例に2020

Author(s)

Journal Title

Data Source

[Journal Article] Phase separation organizes the site of autophagosome formation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Liquidity Is a Critical Determinant for Selective Autophagy of Protein Condensates2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Substrate protein dependence of GroEL-GroES interaction cycle revealed by high-speed AFM imaging2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Observation of the structures and dynamics of the autophagy-related proteins using high-speed AFM2023

Author(s)

Organizer

Data Source

[Presentation] 高速原子間力顕微鏡を用いたオートファジー関連タンパク質のイメージングの試み2023

Author(s)

Organizer

Data Source

[Presentation] ULK1/2-mediated p62-phosphorylation at Ser349 is physiologically important for NRF2 activation2022

Author(s)

Organizer

Data Source

[Presentation] ULK1キナーゼによるp62の液-液相分離制御2022

Noshiro Daisuke 能代大輔

NOSHIRO Daisuke 能代大輔