Takagi Wataru 高木亙

Researcher Number	90755307
Other IDs	https://orcid.org/0000-0002-7882-0223
Affiliation (Current)	2025: 東京大学, 大気海洋研究所, 助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 大気海洋研究所, 助教 2018 – 2023: 東京大学, 大気海洋研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 44040:Morphology and anatomical structure-related Except Principal Investigator Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Basic Section 17050:Biogeosciences-related
Keywords	Principal Investigator 進化 / 遺伝子制御ネットワーク / 発生 / 甲状腺 / 内柱 / ヤツメウナギ / 円口類 / メダカ / 遺伝 / 獲得形質 … More / ATAC-seq / RNA-seq / 海水適応 / エピジェネティクス … More Except Principal Investigator 進化 / 脊椎動物 / トラザメ / 頭部体幹境界 / 化石 / 胚発生 / 糖質 / カワヤツメ / ウズラ / 代謝 / 卵黄 / 卵黄多核層 / 発生 / 糖新生 / グルコース / 遺伝子改変 / 逆遺伝学 / 機能解析 / 繁殖 / 生殖制御メカニズム / 生殖周期 / プレハッチ / 遺伝子導入 / 軟骨魚類 Less

Understanding the dawn of vertebrate morphological evolution based on integrated research of paleontology and evolutionary developmental biology
- Principal Investigator
  
  平沢達矢
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 17050:Biogeosciences-related
- Research Institution
  The University of Tokyo
ヤツメウナギ内柱の発生機序解明と脊索動物内柱の相同性再検証Principal Investigator
- Principal Investigator
  
  高木亙
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  The University of Tokyo
The evolution of yolk metabolism in vertebrate embryos
- Principal Investigator
  
  Furukawa Fumiya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Kitasato University
Introduction of reverse genetic analysis into cartilaginous fish research
- Principal Investigator
  
  HYODO SUSUMU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  The University of Tokyo
Molecular backgrounds for the seawater adaptation in euryhaline medaka (Oryzias latipes).Principal Investigator
- Principal Investigator
  
  Takagi Wataru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Molecular mechanism of nutrient uptake in developing embryos of oviparous cloudy catshark (Scyliorhinus torazame)2022
- Author(s)
  Honda Yuki、Ogawa Nobuhiro、Wong Marty Kwok-Shing、Tokunaga Kotaro、Kuraku Shigehiro、Hyodo Susumu、Takagi Wataru
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 3 Pages: e0265428-e0265428
- DOI
  10.1371/journal.pone.0265428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22414
[Journal Article] Thyroid and endostyle development in cyclostomes provides new insights into the evolutionary history of vertebrates2022
- Author(s)
  Takagi Wataru、Sugahara Fumiaki、Higuchi Shinnosuke、Kusakabe Rie、Pascual-Anaya Juan、Sato Iori、Oisi Yasuhiro、Ogawa Nobuhiro、Miyanishi Hiroshi、Adachi Noritaka、Hyodo Susumu、Kuratani Shigeru
- Journal Title
  
  BMC Biology
  
  Volume: 20 Issue: 1 Pages: 76-76
- DOI
  10.1186/s12915-022-01282-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22414, KAKENHI-PLANNED-17H06385, KAKENHI-PROJECT-20K15830, KAKENHI-PROJECT-22K06243, KAKENHI-PROJECT-22K15153, KAKENHI-PROJECT-19K06683, KAKENHI-PROJECT-19K06794
[Journal Article] N-terminal domain regulates steroid activation of elephant shark glucocorticoid and mineralocorticoid receptors2021
- Author(s)
  Katsu Yoshinao、Shariful Islam M.D.、Lin Xiaozhi、Takagi Wataru、Urushitani Hiroshi、Kohno Satomi、Hyodo Susumu、Baker Michael E.
- Journal Title
  
  The Journal of Steroid Biochemistry and Molecular Biology
  
  Volume: 210 Pages: 105845-105845
- DOI
  10.1016/j.jsbmb.2021.105845
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14740, KAKENHI-PROJECT-19K06734, KAKENHI-PROJECT-19K22414
[Journal Article] Regulation by Progestins, Corticosteroids, and RU486 of Transcriptional Activation of Elephant Shark and Human Progesterone Receptors: An Evolutionary Perspective2021
- Author(s)
  Lin Xiaozhi、Takagi Wataru、Hyodo Susumu、Ijiri Shigeho、Katsu Yoshinao、Baker Michael E.
- Journal Title
  
  ACS Pharmacology & Translational Science
  
  Volume: 5 Issue: 2 Pages: 52-61
- DOI
  10.1021/acsptsci.1c00191
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06734, KAKENHI-PROJECT-19K22414
[Journal Article] Morphological and functional development of the spiral intestine in cloudy catshark (Scyliorhinus torazame)2020
- Author(s)
  Honda Yuki、Takagi Wataru、Wong Marty K. S.、Ogawa Nobuhiro、Tokunaga Kotaro、Kofuji Kazuya、Hyodo Susumu
- Journal Title
  
  Journal of Experimental Biology
  
  Volume: 223 Pages: 1-1
- DOI
  10.1242/jeb.225557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22414, KAKENHI-PROJECT-18K14740
[Journal Article] Facilitated NaCl Uptake in the Highly Developed Bundle of the Nephron in Japanese Red Stingray Hemitrygon akajei Revealed by Comparative Anatomy and Molecular Mapping2020
- Author(s)
  Aburatani Naotaka、Takagi Wataru、Wong Marty Kwok-Sing、Kadota Mitsutaka、Kuraku Shigehiro、Tokunaga Kotaro、Kofuji Kazuya、Saito Kazuhiro、Godo Waichiro、Sakamoto Tatsuya、Hyodo Susumu
- Journal Title
  
  Zoological Science
  
  Volume: 37 Issue: 5 Pages: 458-466
- DOI
  10.2108/zs200038
- NAID
  210000171963
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22414, KAKENHI-PROJECT-20K21429, KAKENHI-PROJECT-18K14740
[Journal Article] Comprehensive analysis of genes contributing to euryhalinity in the bull shark, Carcharhinus leucas; Na+-Cl? co-transporter is one of the key renal factors upregulated in acclimation to low-salinity environment2019
- Author(s)
  Imaseki Itaru、Wakabayashi Midori、Hara Yuichiro、Watanabe Taro、Takabe Souichirou、Kakumura Keigo、Honda Yuki、Ueda Keiichi、Murakumo Kiyomi、Matsumoto Rui、Matsumoto Yosuke、Nakamura Masaru、Takagi Wataru、Kuraku Shigehiro、Hyodo Susumu
- Journal Title
  
  The Journal of Experimental Biology
  
  Volume: 222
- DOI
  10.1242/jeb.201780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22414, KAKENHI-PROJECT-16H04812, KAKENHI-PROJECT-17H03868
[Journal Article] Transcriptional activation of elephant shark mineralocorticoid receptor by corticosteroids, progesterone, and spironolactone.2019
- Author(s)
  Katsu Y, Kohno S, Oka K, Lin X, Otake S, Pillai NE, Takagi W, Hyodo S, Venkatesh B, Baker ME
- Journal Title
  
  Science Signaling
  
  Volume: 12 Issue: 584 Pages: 1-10
- DOI
  10.1126/scisignal.aar2668
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06734, KAKENHI-PROJECT-19K22414, KAKENHI-PROJECT-17H03868
[Presentation] Gluconeogenesis in the YSL-like tissue of cloudy catshark (Scyliorhinus torazame)2024
- Author(s)
  Marino Shimizu, Wataru Takagi, Isana Kayanuma, Yuki Sakai, Kotaro Tokunaga, Susumu Hyodo, Fumiya Furukawa
- Organizer
  15th International Congress on the Biology of Fish
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19276
[Presentation] Expression of gluconeogenic genes in the yolk sac of cloudy catshark (Scyliorhinus torazame)2023
- Author(s)
  Marino Shimizu, Wataru Takagi, Isana Kayanuma, Yuki Sakai, Kotaro Tokunaga, Susumu Hyodo, Fumiya Furukawa
- Organizer
  International Symposium on Aquatic Animal Physiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19276
[Presentation] Expression of gluconeogenic genes in the yolk sac of cloudy catshark2023
- Author(s)
  Marino Shimizu, Wataru Takagi, Isana Kayanuma, Yuki Sakai, Kotaro Tokunaga, Susumu Hyodo, Fumiya Furukawa
- Organizer
  International Symposium on Aquatic Animal Physiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19276
[Presentation] トラザメ胚における消化吸収機構の発達2021
- Author(s)
  本田祐基、高木亙、小川展弘、徳永幸太郎、小藤一弥、工樂樹洋、兵藤晋
- Organizer
  日本動物学会第92回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] アカエイ腎臓における淡水適応の分子メカニズム2021
- Author(s)
  油谷直孝、高木亙、工樂樹洋、齊藤和裕、牛堂和一郎、坂本竜哉、兵藤晋
- Organizer
  日本動物学会第92回大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] トラザメの卵胞における性ステロイドホルモン合成の変動2021
- Author(s)
  川野真依、齋藤萌々子、有村省吾、下山紘也、徳永幸太郎、高木亙、黄國成、兵藤晋
- Organizer
  第45回日本比較内分泌学会大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] トラザメにおいてプロゲステロンは卵殻の一部であるツルの形成を誘導する2021
- Author(s)
  下山紘也、井上拓人、齋藤萌々子、有村省吾、小林牧人、徳永幸太郎、高木亙、兵藤晋
- Organizer
  第45回日本比較内分泌学会大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] トラザメ産卵周期におけるプロゲステロンの役割2021
- Author(s)
  下山紘也、井上拓人、齋藤萌々子、有村省吾、小林牧人、徳永幸太郎、高木亙、兵藤晋
- Organizer
  日本動物学会第92回大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] トラザメの卵胞発育に伴う生殖腺刺激ホルモン受容体の発現動態と機能解析2021
- Author(s)
  有村省吾、齋藤萌々子、下山紘也、徳永幸太郎、高木亙、兵藤晋
- Organizer
  第45回日本比較内分泌学会大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] エコー検査を用いたトラザメ(Scyliorhinus torazame)の産卵周期における性ステロイドホルモンの役割の研究2020
- Author(s)
  下山紘也、井上拓人、斎藤萌々子、有村省吾、小林牧人、徳永幸太郎、高木亙、兵藤晋
- Organizer
  日本動物学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] トラザメにおける生殖腺刺激ホルモン受容体の解析2020
- Author(s)
  有村省吾、下山紘也、齋藤萌々子、徳永幸太郎、高木亙、兵藤晋
- Organizer
  日本動物学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] エコー検査を活用したトラザメの産卵周期同定と血中性ステロイドホルモンの変動2020
- Author(s)
  井上拓人、齊藤萌々子、池羽希理子、高木亙、村雲清美、佐藤圭一、徳永幸太郎、小藤一弥、兵藤晋
- Organizer
  令和2年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] 軟骨魚類の中でもユニークなエイ類の腎ネフロン：尿の組成と形態的特徴から考察する機能2020
- Author(s)
  油谷直孝、兵藤晋、高木亙
- Organizer
  第30回バゾプレシン研究会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] トラザメの産卵サイクルの制御メカニズム：エコー検査と血中ステロイドホルモンの測定2019
- Author(s)
  井上拓人、齊藤萌々子、高木亙、村雲清美、佐藤圭一、徳永幸太郎、小藤一弥、兵藤晋
- Organizer
  第4回軟骨魚類研究会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] トラザメ胚発生における卵黄嚢上皮ならびに消化管での栄養吸収輸送体の発現解析2019
- Author(s)
  本田祐基、高木亙、徳永幸太郎、小藤一弥、工樂樹洋、兵藤晋
- Organizer
  日本動物学会第90回大会
- Data Source
  KAKENHI-PROJECT-19K22414
[Presentation] エコー検査を活用したトラザメの産卵周期と性ステロイドホルモン変動2019
- Author(s)
  井上拓人、池羽希理子、徳永幸太郎、小藤一弥、高木亙、兵藤晋
- Organizer
  第44回日本比較内分泌学会大会
- Data Source
  KAKENHI-PROJECT-19K22414

1. HYODO SUSUMU (40222244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
2. Furukawa Fumiya (80750281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 神田真司 (50634284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 藤森千加 (50750775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 平沢達矢 (60585793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 勝義直

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Takagi Wataru 高木 亙

Research Projects

Research Products

Co-Researchers

Understanding the dawn of vertebrate morphological evolution based on integrated research of paleontology and evolutionary developmental biology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヤツメウナギ内柱の発生機序解明と脊索動物内柱の相同性再検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The evolution of yolk metabolism in vertebrate embryos

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Introduction of reverse genetic analysis into cartilaginous fish research

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular backgrounds for the seawater adaptation in euryhaline medaka (Oryzias latipes).Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Molecular mechanism of nutrient uptake in developing embryos of oviparous cloudy catshark (Scyliorhinus torazame)2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thyroid and endostyle development in cyclostomes provides new insights into the evolutionary history of vertebrates2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-terminal domain regulates steroid activation of elephant shark glucocorticoid and mineralocorticoid receptors2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation by Progestins, Corticosteroids, and RU486 of Transcriptional Activation of Elephant Shark and Human Progesterone Receptors: An Evolutionary Perspective2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Morphological and functional development of the spiral intestine in cloudy catshark (Scyliorhinus torazame)2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Facilitated NaCl Uptake in the Highly Developed Bundle of the Nephron in Japanese Red Stingray Hemitrygon akajei Revealed by Comparative Anatomy and Molecular Mapping2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Comprehensive analysis of genes contributing to euryhalinity in the bull shark, Carcharhinus leucas; Na+-Cl? co-transporter is one of the key renal factors upregulated in acclimation to low-salinity environment2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptional activation of elephant shark mineralocorticoid receptor by corticosteroids, progesterone, and spironolactone.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Gluconeogenesis in the YSL-like tissue of cloudy catshark (Scyliorhinus torazame)2024

Author(s)

Organizer

Data Source

[Presentation] Expression of gluconeogenic genes in the yolk sac of cloudy catshark (Scyliorhinus torazame)2023

Takagi Wataru 高木亙