SEKI DAISUKE 関大輔

Researcher Number	90758442
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2020: 東北大学, 歯学研究科, 大学院非常勤講師 2018: 東北大学, 大学病院, 助教 2016 – 2017: 東北大学, 歯学研究科, 助教 2015: 東北大学, 歯学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Orthodontics/Pediatric dentistry Except Principal Investigator Basic Section 57070:Developmental dentistry-related / Orthodontics/Pediatric dentistry
Keywords	Principal Investigator 再生医療 / 歯 / iPS細胞 / 歯学 Except Principal Investigator CCN2/CTGF / methionin enkephalin / 機械的刺激 / methionine enkephalin / アポトーシス / 骨細胞 … More / iPS細胞 / Hif1α / 歯性上皮細胞 / iPS / Hif Less

Roles of methionine enkephalin produced by osteocytes in mechanical stress-induced bone metabolism
- Principal Investigator
  
  Takeshita Nobuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tohoku University
Establishment of a novel method for including iPS cell-derived odontogenic epithelial cells based on the elucidation of the role of Hif1a
- Principal Investigator
  
  Yoshida Michiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tohoku University
Induction of differentiation of dental mesenchymal cells from human iPS cellsPrincipal Investigator
- Principal Investigator
  
  Seki Daisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tohoku University
Development of method for generation of iPS cell-derived odontogenic cells by gene transfectionPrincipal Investigator
- Principal Investigator
  
  SEKI DAISUKE
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tohoku University

All 2020 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc12020
- Author(s)
  Sogi Chisumi、Takeshita Nobuo、Jiang Wei、Kim Siyoung、Maeda Toshihiro、Yoshida Michiko、Oyanagi Toshihito、Ito Arata、Kimura Seiji、Seki Daisuke、Takano Ikuko、Sakai Yuichi、Fujiwara Ikuma、Kure Shigeo、Takano‐Yamamoto Teruko
- Journal Title
  
  JBMR Plus
  
  Volume: 4 Issue: 7 Pages: 1-13
- DOI
  10.1002/jbm4.10369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19257, KAKENHI-PROJECT-20K18775, KAKENHI-PROJECT-18K09828, KAKENHI-PROJECT-18K17241, KAKENHI-PROJECT-19K24085
[Journal Article] Insulin-like growth factor 1 modulates bioengineered tooth morphogenesis.2019
- Author(s)
  Oyanagi T, Takeshita N, Hara M, Ikeda E, Chida T, Seki D, Yoshida M, Seiryu M, Takano I, Kimura S, Oshima M, Tsuji T, Takano-Yamamoto T
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 368-368
- DOI
  10.1038/s41598-018-36863-6
- NAID
  120006875661
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11928, KAKENHI-PROJECT-18K09828, KAKENHI-PROJECT-17K17304, KAKENHI-PROJECT-18K17241, KAKENHI-PROJECT-19K10375, KAKENHI-PROJECT-17K11931
[Journal Article] Improvement of Open Bite and Stomatognathic Function in an Axenfeld- Rieger Syndrome Patient by Orthodontic Sectional Arch Mechanics: Clinical Considerations and the Risk of Orthodontic Tooth Movement2019
- Author(s)
  Daisuke Seki, Nobuo Takeshita, Masahiro Seiryu, Toru Deguchi, Teruko Takano-Yamamoto
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 73 Issue: 3 Pages: 255-262
- DOI
  10.18926/AMO/56869
- NAID
  120006648005
- URL
  https://ousar.lib.okayama-u.ac.jp/56869
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09828, KAKENHI-PROJECT-19K10375, KAKENHI-PROJECT-17K11931, KAKENHI-PROJECT-17K17304
[Journal Article] In vivo expression and regulation of genes associated with vascularization during early response of sutures to tensile force.2016
- Author(s)
  Nobuo Takeshita, Masakazu Hasegawa, Kiyo Sasaki, Daisuke Seki, Masahiro Seiryu, Shunro Miyashita, Ikuko Takano, Toshihito Oyanagi, Yuki Miyajima, Teruko Takano-Yamamoto.
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06048
[Journal Article] In vivo expression and regulation of genes associated with vascularization during early response of sutures to tensile force2016
- Author(s)
  Takeshita N, Hasegawa M, Sasaki K, Seki D, Seiryu M, Miyashita S, Takano I, Oyanagi T, Miyajima Y, Takano-Yamamoto T
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 印刷中 Issue: 1 Pages: 40-51
- DOI
  10.1007/s00774-016-0737-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05048, KAKENHI-PROJECT-15H06048, KAKENHI-PROJECT-26463084, KAKENHI-PROJECT-15K11336, KAKENHI-PROJECT-16K20634
[Presentation] Ten-m/Odz3はFGF2によるRhoA活性制御を介してATDC5のアクチン再構成、遊走、分化を促す2018
- Author(s)
  竹下信郎、高野郁子、関大輔、大柳俊仁、吉田倫子、山本照子
- Organizer
  第３６回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09828
[Presentation] Odz3はRhoA、アクチン制御を介した遊走促進および分化の促進により、ATDC5の軟骨細胞分化を調整する2018
- Author(s)
  高野郁子、竹下信郎、関大輔、大柳俊仁、吉田倫子、木村晴地、川津正慶、山本照子
- Organizer
  第７７回日本矯正歯科学会大会
- Data Source
  KAKENHI-PROJECT-18K09828
[Presentation] IGF1 regulates morphogenesis of bioengineered teeth via proliferation and differentiation of dental epithelial and mesenchymal cells2018
- Author(s)
  Toshihito Oyanagi，Nobuo Takeshita，Mamiko Hara，Etsuko Ikeda， Toko Chida，Daisuke Seki，Michiko Yoshida，Masahiro Seiryu，Ikuko Takano，Seiji Kimura，Masamitsu Oshima，Takashi Tsuji，Teruko Takano-Yamamoto,
- Organizer
  5th Tissue Engineering and Regenerative Medicine International Society World Congress, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-17K17304
[Presentation] 膜タンパク質Ten-m/Odz3はFGF2によるRhoA活性制御を介してATDC5のアクチン再構成、遊走、分化を促す2018
- Author(s)
  竹下信郎、高野郁子、関大輔、大柳俊仁、吉田倫子、山本照子
- Organizer
  第３６回日本骨代謝学会学術集会、長崎
- Data Source
  KAKENHI-PROJECT-17K17304
[Presentation] Odz3はRhoA、アクチン制御を介した遊走促進および分化の促進により、ATDC5の軟骨細胞分化を調整する2018
- Author(s)
  高野郁子、竹下信郎、関大輔、大柳俊仁、吉田倫子、木村晴地、川津正慶、山本照子
- Organizer
  第７７回日本矯正歯科学会大会、横浜
- Data Source
  KAKENHI-PROJECT-17K17304
[Presentation] IGF1 regulates morphogenesis of bioengineered teeth via proliferation and differentiation of dental epithelial and mesenchymal cells.2018
- Author(s)
  435.Oyanagi T, Takeshita N, Hara M, Ikeda E, Chida T, Seki D, Yoshida M, Seiryu M, Takano I, Kimura S, Oshima M, Tsuji T, Takano-Yamamoto T
- Organizer
  5th TERMIS World Congress.
- Data Source
  KAKENHI-PROJECT-17K11928
[Presentation] Odz3はRhoAとアクチンの制御を介した遊走と分化の促進によりATDC5の軟骨細胞分化を調整する2018
- Author(s)
  高野郁子、竹下信郎、関大輔、大柳俊仁、吉田倫子、木村晴地、川津正慶、山本照子
- Organizer
  第77回日本矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11928
[Presentation] IGF1 regulates morphogenesis of bioengineered teeth via proliferation and differentiation of dental epithelial and mesenchymal cells2018
- Author(s)
  Toshihito Oyanagi，Nobuo Takeshita，Mamiko Hara，Etsuko Ikeda， Toko Chida，Daisuke Seki，Michiko Yoshida，Masahiro Seiryu，Ikuko Takano，Seiji Kimura，Masamitsu Oshima，Takashi Tsuji，Teruko Takano-Yamamoto
- Organizer
  5th Tissue Engineering and Regenerative Medicine International Society World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09828
[Presentation] 膜タンパク質Ten-m/Odz3はFGF2によるRhoA活性制御を介してATDC5のアクチン再構成、遊走、分化を促す2018
- Author(s)
  竹下信郎、高野郁子、関大輔、大柳俊仁、吉田倫子、山本照子
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11928
[Presentation] CCN2/CTGFは牽引力が負荷された頭蓋縫合における骨および血管の形成を制御する2016
- Author(s)
  竹下信郎、佐々木紀代、関大輔、清流正弘、宮下俊郎、高野郁子、大柳俊仁、長谷川正和、山本照子
- Organizer
  第７５回日本矯正歯科学会大会
- Place of Presentation
  徳島
- Year and Date
  2016-11-07
- Data Source
  KAKENHI-PROJECT-15H06048
[Presentation] CCN2/CTGFは牽引力が負荷された頭蓋縫合における血管および骨の形成を制御する2016
- Author(s)
  竹下信郎、佐々木紀代、関大輔、宮下俊郎、高野郁子、大柳俊仁、山本照子
- Organizer
  第３４回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15H06048
[Presentation] IGF1による再生歯の形態制御とそのメカニズム解析2016
- Author(s)
  大柳俊仁、竹下信郎、関大輔、原真美子、池田悦子、高野郁子、清流正弘、吉田倫子、山本照子
- Organizer
  第３４回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15H06048
[Presentation] 機械的刺激が促す骨形成過程における前駆骨芽細胞凝集へのCCN2/CTGFの影響2016
- Author(s)
  竹下信郎、関大輔、清流正弘、木村晴地、高野郁子、大柳俊仁、吉田倫子、長谷川正和、山本照子
- Organizer
  第８回日本CCNファミリー研究会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-15H06048
[Presentation] 遺伝子導入を応用したiPS細胞由来象牙芽細胞様細胞の新規分化誘導法の開発2016
- Author(s)
  関大輔、竹下信郎、大柳俊仁、高野郁子、佐々木周太郎、長谷川正和、山本照子
- Organizer
  第15回再生医療学会総会
- Place of Presentation
  大阪
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15H06048
[Presentation] Differentiation of Odontoblast-Like Cells from Mouse Induced Pluripotent Stem Cells by Pax9 and Bmp4 Transfection.2015
- Author(s)
  関大輔、竹下信郎、大柳俊仁、高野郁子、佐々木周太郎、長谷川正和、山本照子
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H06048
[Presentation] 遺伝子導入を応用したiPS細胞由来象牙芽細胞様細胞の新規分化誘導法の開発2015
- Author(s)
  関大輔、竹下信郎、大柳俊仁、高野郁子、佐々木周太郎、長谷川正和、山本照子
- Organizer
  第74回日本矯正歯科学会
- Place of Presentation
  博多
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15H06048

1. TAKESHITA NOBUO (50431515)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. YAMAMOTO TERUKO (00127250)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. Yoshida Michiko (80746818)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 高野郁子 (90770462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SEIRYU Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 佐々木紀代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 前田敏博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SEKI DAISUKE 関 大輔

Research Projects

Research Products

Co-Researchers

Roles of methionine enkephalin produced by osteocytes in mechanical stress-induced bone metabolism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a novel method for including iPS cell-derived odontogenic epithelial cells based on the elucidation of the role of Hif1a

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of differentiation of dental mesenchymal cells from human iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of method for generation of iPS cell-derived odontogenic cells by gene transfectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Methionine Enkephalin Suppresses Osteocyte Apoptosis Induced by Compressive Force through Regulation of Nuclear Translocation of NFATc12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insulin-like growth factor 1 modulates bioengineered tooth morphogenesis.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Improvement of Open Bite and Stomatognathic Function in an Axenfeld- Rieger Syndrome Patient by Orthodontic Sectional Arch Mechanics: Clinical Considerations and the Risk of Orthodontic Tooth Movement2019

Author(s)

Journal Title

DOI

NAID

URL

Language

Data Source

[Journal Article] In vivo expression and regulation of genes associated with vascularization during early response of sutures to tensile force.2016

Author(s)

Journal Title

Data Source

[Journal Article] In vivo expression and regulation of genes associated with vascularization during early response of sutures to tensile force2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Ten-m/Odz3はFGF2によるRhoA活性制御を介してATDC5のアクチン再構成、遊走、分化を促す2018

Author(s)

Organizer

Data Source

[Presentation] Odz3はRhoA、アクチン制御を介した遊走促進および分化の促進により、ATDC5の軟骨細胞分化を調整する2018

Author(s)

Organizer

Data Source

[Presentation] IGF1 regulates morphogenesis of bioengineered teeth via proliferation and differentiation of dental epithelial and mesenchymal cells2018

Author(s)

Organizer

Data Source

[Presentation] 膜タンパク質Ten-m/Odz3はFGF2によるRhoA活性制御を介してATDC5のアクチン再構成、遊走、分化を促す2018

Author(s)

Organizer

Data Source

[Presentation] Odz3はRhoA、アクチン制御を介した遊走促進および分化の促進により、ATDC5の軟骨細胞分化を調整する2018

Author(s)

Organizer

Data Source

[Presentation] IGF1 regulates morphogenesis of bioengineered teeth via proliferation and differentiation of dental epithelial and mesenchymal cells.2018

Author(s)

Organizer

Data Source

SEKI DAISUKE 関大輔