tsuchiya hikaru 土屋光

… Alternative Names

Researcher Number	90760132
Other IDs
Affiliation (Current)	2020: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主任研究員 2020: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主任研究員
Affiliation (based on the past Project Information) *help	2020: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主任研究員 2019 – 2020: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主任研究員 2015 – 2018: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator タンパク質分解 / ユビキチン / 蛋白質分解 Except Principal Investigator ユビキチン / 翻訳後修飾 / タンパク質分解 / タンパク質 / シグナル伝達 / プロテアソーム / 蛋白質

プロテアソーム結合ユビキチンリガーゼによるタンパク質分解制御Principal InvestigatorOngoing
- Principal Investigator
  
  土屋光
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
シャトル分子を介したプロテアソーム活性制御機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  土屋光
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
分岐型ユビキチン鎖が司る新たなシグナル伝達機構Ongoing
- Principal Investigator
  
  大竹史明
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
  Tokyo Metropolitan Institute of Medical Science
A method for determining ubiquitin chain length in cellsPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Hikaru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science

All 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Methods to measure ubiquitin chain length and linkage.2019
- Author(s)
  Ohtake, F., Tsuchiya, H., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 618 Pages: 105-133
- DOI
  10.1016/bs.mie.2018.12.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14913, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993
[Journal Article] Detection of ubiquitination activity and identification of ubiquitinated substrates using TR-TUBE.2019
- Author(s)
  Yoshida, Y., Saeki, Y., Tsuchiya, H., and Tanaka, K.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 618 Pages: 135-147
- DOI
  10.1016/bs.mie.2018.12.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14913, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-16K07705
[Journal Article] K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains.2018
- Author(s)
  Ohtake, F., Tsuchiya, H., Saeki, Y., and Tanaka, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 115 Pages: 1401-1408
- DOI
  10.1073/pnas.1716673115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14702, KAKENHI-PROJECT-26293018, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-26000014
[Journal Article] Ub-ProT reveals global length and composition of protein ubiquitylation in cells.2018
- Author(s)
  Tsuchiya, H., Burana, D., Ohtake, F., Arai, N., Kaiho, A., Komada, M., and Tanaka, K.*, and Saeki, Y. * (*Correspondence)
- Journal Title
  
  Nat. Commun.
  
  Volume: 9 Pages: 524-524
- DOI
  10.1038/s41467-018-02869-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14702, KAKENHI-PROJECT-26293018, KAKENHI-PUBLICLY-17H05681, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-26000014
[Journal Article] The emerging complexity of ubiquitin architecture2017
- Author(s)
  Ohtake, F., and Tsuchiya, H
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 161 Pages: 125-133
- DOI
  10.1093/jb/mvw088
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H06882, KAKENHI-PLANNED-24112004, KAKENHI-PROJECT-16K14702
[Journal Article] In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-linked Chain Specificity of the Proteasome2017
- Author(s)
  Hikaru Tsuchiya, Fumiaki Ohtake, Naoko Arai, Ai Kaiho, Sayaka Yasuda, Keiji Tanaka, and Yasushi Saeki
- Journal Title
  
  Molecular Cell
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H06882
[Presentation] ユビキチン鎖長決定法の開発2018
- Author(s)
  土屋光、新井直子、海保愛、田中啓二、佐伯泰
- Organizer
  第91回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K14913
[Presentation] Ubiquitin chain selectivity of ubiquitin-binding proteins in yeast2016
- Author(s)
  Hikaru Tsuchiya
- Organizer
  7th PROTEASOME and AUTOPHAGY WORKSHOP
- Place of Presentation
  Clermont-Ferrand, France
- Year and Date
  2016-04-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06882
[Presentation] プロテアソーム依存的タンパク質分解経路におけるユビキチン鎖選択制の解析2015
- Author(s)
  土屋光、吉原英人、新井直子、海保愛、田中啓二、佐伯泰
- Organizer
  第38回日本分子生物学会第88回　日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド (兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H06882

1. 大竹史明 (60447373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. SAEKI Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
3. KAIHO Ai

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 田中啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 吉田雪子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

tsuchiya hikaru 土屋 光

TSUCHIYA Hikaru 土屋 光

Research Projects

Research Products

Co-Researchers

プロテアソーム結合ユビキチンリガーゼによるタンパク質分解制御Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シャトル分子を介したプロテアソーム活性制御機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分岐型ユビキチン鎖が司る新たなシグナル伝達機構Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A method for determining ubiquitin chain length in cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Methods to measure ubiquitin chain length and linkage.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of ubiquitination activity and identification of ubiquitinated substrates using TR-TUBE.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ub-ProT reveals global length and composition of protein ubiquitylation in cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The emerging complexity of ubiquitin architecture2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-linked Chain Specificity of the Proteasome2017

Author(s)

Journal Title

Data Source

[Presentation] ユビキチン鎖長決定法の開発2018

Author(s)

Organizer

Data Source

[Presentation] Ubiquitin chain selectivity of ubiquitin-binding proteins in yeast2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] プロテアソーム依存的タンパク質分解経路におけるユビキチン鎖選択制の解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

tsuchiya hikaru 土屋光

TSUCHIYA Hikaru 土屋光