Takakura Daisuke 高倉大輔

… Alternative Names

高倉大輔タカクラダイスケ

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Researcher Number	90760231
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 生命医科学研究科, 特任教員
Affiliation (based on the past Project Information) *help	2020 – 2024: 横浜市立大学, 生命医科学研究科, 特任教員 2016: 横浜市立大学, 生命医科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / 0801:Pharmaceutical sciences and related fields / Physical pharmacy Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Keywords	Principal Investigator LC/MS / 糖鎖 / LC/MS/MS / がん / グライコプロテオミクス / 乳がん / B7-H3 / O-結合型糖鎖 / 臨床グライコプロテオミクス / 創薬標的 … More / O-型糖鎖 / プロテオミクス / O-グライコプロテオミクス / 大腸がん / 糖鎖不均一性 / 生物物理 / リソソーム … More Except Principal Investigator LC/MS/MS / 神経分化 / グライコプロテオミクス / 糖鎖 / iPS細胞 / プロテオミクス / 品質評価 / 細胞外小胞 / 幹細胞 / バイセクト糖鎖 / 神経変性疾患マーカー / 糖鎖生合成酵素 / アルツハイマー病 / 分子マーカー / 糖鎖合成酵素 / データ非依存的データ取得法 / OGlcNAc / O-GlcNAc / デ―タ非依存的データ取得 / 神経変性疾患 / 質量分析 / 再生治療 / 糖タンパク質 / 分化マーカー / 再生医療 / 神経細胞 Less

Development of a method for predicting cell quality in continuous production for the practical application of stem cell products - the use of extracellular vesicles
- Principal Investigator
  
  川崎ナナ
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Yokohama City University
個別化医療に向けたB7-H3糖鎖と活性化T細胞によるがん細胞認識との関係の解明Principal Investigator
- Principal Investigator
  
  高倉大輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Yokohama City University
Elucidation of molecular mechanisms of neuronal differentiation and search for molecular markers of neurodegenerative diseases by glycoproteomics.
- Principal Investigator
  
  Kawasaki Nana
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Yokohama City University
Clinical O-glycopeptidomics for the exploration of therapeutic targets for colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Takakura Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0801:Pharmaceutical sciences and related fields
- Research Institution
  Yokohama City University
Development of evaluation markers for differentiation of iPS cell-derived cells in drug discovery and regenerative medicine
- Principal Investigator
  
  Kawasaki Nana
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Yokohama City University
リソソーム膜タンパク質糖鎖のがん性変異と細胞内局在制御との関係の解明Principal Investigator
- Principal Investigator
  
  高倉大輔
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Yokohama City University

All 2024 2023 2021 2020 2016

All Journal Article Presentation

[Journal Article] Comparative Analysis of Site-Specific N-glycosylation of LAMP1 from Breast Cancer Tissues2024
- Author(s)
  Ohashi Shoko、Takakura Daisuke、Kobayashi Noritoshi、Tokuhisa Motohiko、Ichikawa Yasushi、Kawasaki Nana
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 175 Issue: 5 Pages: 561-572
- DOI
  10.1093/jb/mvae001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K04800, KAKENHI-PROJECT-23K06719, KAKENHI-PROJECT-21H02617
[Journal Article] Comprehensive Membrane <i>N</i>-Glycoproteomics Using Human Breast Cancer Cell Line Pairs2023
- Author(s)
  Takakura Daisuke、Yoshida Haruka、Ohashi Shoko、Kawasaki Nana
- Journal Title
  
  Mass Spectrometry
  
  Volume: 12 Issue: 1 Pages: A0117-A0117
- DOI
  10.5702/massspectrometry.A0117
- ISSN
  2186-5116, 2187-137X
- Year and Date
  2023-04-11
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02617
[Journal Article] Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice2023
- Author(s)
  Wei Heng、Naruse Chie、Takakura Daisuke、Sugihara Kazushi、Pan Xuchi、Ikeda Aki、Kawasaki Nana、Asano Masahide
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 01-14
- DOI
  10.3389/fimmu.2023.1272537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02617
[Journal Article] O-GalNAc glycosylation determines intracellular trafficking of APP and Aβ production2023
- Author(s)
  Tachida Yuriko、Iijima Junko、Takahashi Kazuto、Suzuki Hideaki、Kizuka Yasuhiko、Yamaguchi Yoshiki、Tanaka Katsunori、Nakano Miyako、Takakura Daisuke、Kawasaki Nana、Saito Yuko、Manya Hiroshi、Endo Tamao、Kitazume Shinobu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 7 Pages: 104905-104905
- DOI
  10.1016/j.jbc.2023.104905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15665, KAKENHI-PROJECT-22K16448, KAKENHI-PROJECT-22K20653, KAKENHI-PROJECT-21H02617
[Journal Article] Glycoproteomic analysis of the changes in protein N-glycosylation during neuronal differentiation in human-induced pluripotent stem cells and derived neuronal cells2021
- Author(s)
  Kazumasa Kimura, Takumi Koizumi, Takaya Urasawa, Yuki Ohta, Daisuke Takakura, Nana Kawasaki
- Journal Title
  
  Sci. Rep.
  
  Volume: 11 Issue: 1 Pages: 11169-11169
- DOI
  10.1038/s41598-021-90102-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02617
[Journal Article] Monitoring the glycosylation of AMPA (a-amino-3-hydroxy-5-methyl-4isoxazole-propionate)-type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N-glycosylation occupancy by molecular chaperones in Mice.2020
- Author(s)
  Midorikawa R, Takakura D, Morise J, Wakazono Y, Kawasaki N, Oka S, Takamiya K.
- Journal Title
  
  J. Neurochem.
  
  Volume: 0 Issue: 5 Pages: 1-19
- DOI
  10.1111/jnc.14964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16074, KAKENHI-PROJECT-18H02563, KAKENHI-PROJECT-17K08541, KAKENHI-PROJECT-19H03370
[Presentation] データ非依存的取得質量分析法を用いた神経分化関連O-GlcNAc修飾タンパク質の探索2023
- Author(s)
  保科隼佑・浦澤貴哉・西村梨香・高倉大輔・川崎ナナ
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02617
[Presentation] O-GlcNAcプロテオミクスによるパーキンソン病モデル細胞の神経分化におけるO-GlcNAc修飾の解析2023
- Author(s)
  保科隼佑・浦澤貴哉・西村梨香・芳﨑雅人・高倉大輔・菅原亨・川崎ナナ
- Organizer
  グライコ東京2023
- Data Source
  KAKENHI-PROJECT-21H02617
[Presentation] データ非依存的取得法を用いた細胞内O-GlcNAc修飾タンパク質の定量解析2023
- Author(s)
  保科隼佑・西村梨香・浦澤貴哉・高倉大輔・川崎ナナ
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-21H02617
[Presentation] O-GlcNAcプロテオミクス手法の開発とパーキンソン病モデル細胞の神経分化におけるO-GlcNAc修飾の網羅的解析2023
- Author(s)
  保科隼佑・浦澤貴哉・西村梨香・芳﨑雅人・高倉大輔・菅原亨・川崎ナナ
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21H02617
[Presentation] ヒトiPS細胞の神経分化に伴うプロテオグリカンプロファイルの解析2023
- Author(s)
  高下寛生、西村梨香、高倉大輔、川崎ナナ
- Organizer
  グライコ東京2023
- Data Source
  KAKENHI-PROJECT-21H02617
[Presentation] データ非依存的取得LC/MS/MSを用いたヒト人工多能性幹細胞神経分化におけるリン酸化タンパク質の定量解析2023
- Author(s)
  勝野恵梨・西村梨香・高倉大輔・川崎ナナ
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02617
[Presentation] グライコプロテオーム解析プラットフォームの開発と大腸がん診断・治療標的の探索2021
- Author(s)
  高倉大輔
- Organizer
  JCGG2021
- Invited
- Data Source
  KAKENHI-PROJECT-20K22712
[Presentation] 臨床O-グライコプロテオミクスによる大腸がんO-型糖鎖修飾タンパク質の探索2021
- Author(s)
  高倉大輔、我妻孝則、大橋祥子、小林規俊、廣島幸彦、徳久元彦、市川靖史、川崎ナナ
- Organizer
  第40回日本糖質学会
- Data Source
  KAKENHI-PROJECT-20K22712
[Presentation] ヒトiPS細胞の神経分化に伴う糖タンパク質合成とN型糖鎖修飾の変化の解析2021
- Author(s)
  木村一雅、浦澤貴哉、小泉匠、高倉大輔、太田悠葵、川崎ナナ
- Organizer
  第69回日本質量分析学会総合討論会
- Data Source
  KAKENHI-PROJECT-21H02617
[Presentation] ヒトiPS細胞の神経分化に伴う膜タンパク質のN型糖鎖修飾の変化2020
- Author(s)
  木村一雅、小泉匠、浦澤貴哉、太田悠葵、高倉大輔、川崎ナナ
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-18H02563
[Presentation] グライコプロテオミクス技術による乳がん細胞糖タンパク質の腫瘍関連グリコフォーム解析2016
- Author(s)
  高倉大輔、吉田晴香、川崎ナナ
- Organizer
  日本プロテオーム学会２０１６年大会
- Place of Presentation
  北里大学薬学部白金キャンパス　（東京都・港区）
- Data Source
  KAKENHI-PROJECT-16K18864
[Presentation] 乳がん細胞糖タンパク質糖鎖のミクロ不均一性変化の解析2016
- Author(s)
  高倉大輔、吉田晴香、川崎ナナ
- Organizer
  第３５回日本糖質学会年会
- Place of Presentation
  高知市文化プラザかるぽーと　（高知県・高知市）
- Data Source
  KAKENHI-PROJECT-16K18864
[Presentation] 乳がん細胞膜糖タンパク質の部位特異的なN-型糖鎖変化2016
- Author(s)
  吉田晴香、高倉大輔、川崎ナナ
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-16K18864

1. Kawasaki Nana (20186167)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. 太田悠葵 (10583453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 大橋祥子 (00908709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 菅原亨 (70553460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MORISE Jyoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 鈴木英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takakura Daisuke 高倉 大輔

高倉 大輔 タカクラ ダイスケ

Research Projects

Research Products

Co-Researchers

Development of a method for predicting cell quality in continuous production for the practical application of stem cell products - the use of extracellular vesicles

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

個別化医療に向けたB7-H3糖鎖と活性化T細胞によるがん細胞認識との関係の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanisms of neuronal differentiation and search for molecular markers of neurodegenerative diseases by glycoproteomics.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinical O-glycopeptidomics for the exploration of therapeutic targets for colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of evaluation markers for differentiation of iPS cell-derived cells in drug discovery and regenerative medicine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

リソソーム膜タンパク質糖鎖のがん性変異と細胞内局在制御との関係の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Comparative Analysis of Site-Specific N-glycosylation of LAMP1 from Breast Cancer Tissues2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive Membrane <i>N</i>-Glycoproteomics Using Human Breast Cancer Cell Line Pairs2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] O-GalNAc glycosylation determines intracellular trafficking of APP and Aβ production2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycoproteomic analysis of the changes in protein N-glycosylation during neuronal differentiation in human-induced pluripotent stem cells and derived neuronal cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monitoring the glycosylation of AMPA (a-amino-3-hydroxy-5-methyl-4isoxazole-propionate)-type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N-glycosylation occupancy by molecular chaperones in Mice.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] データ非依存的取得質量分析法を用いた神経分化関連O-GlcNAc修飾タンパク質の探索2023

Author(s)

Organizer

Data Source

[Presentation] O-GlcNAcプロテオミクスによるパーキンソン病モデル細胞の神経分化におけるO-GlcNAc修飾の解析2023

Author(s)

Takakura Daisuke 高倉大輔

高倉大輔タカクラダイスケ