Nakajima Kensuke 中島健輔

Researcher Number	90762162
Other IDs
Affiliation (Current)	2025: 長崎国際大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2025: 長崎国際大学, 薬学部, 助教 2018 – 2023: 長崎国際大学, 薬学部, 助教 2015 – 2018: 長崎国際大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Eating habits / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator 末梢組織 / BDNF / うつ病 / カンキツ / ACHN細胞 / 血液脳関門 / 脳由来神経栄養因子 / 脳由来神経栄養因子(BDNF) / 血清BDNF濃度 / アワ … More / 亜鉛 / 未精製小麦 / 脳由来神経栄養因子（BDNF） / 柑橘類 / チンピ / 和漢薬 / 穀類 / 末梢性BDNF産生促進物質 / 食品成分 / 末梢性BDNF / 新規抗うつ薬 / 食欲抑制 / 肥満 / 摂食抑制 / 天然化合物 / グレリン / トリテルペン / EGCG / カルボキシル基 / トリテルペン類 / 抗肥満 / 活性型グレリン Less

Assessing the potential of citrus as novel antidepressant drug seeds and food supplements acting on peripheral tissuesPrincipal Investigator
- Principal Investigator
  
  中島健輔
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki International University
Development of citrus-based prophylactic and antidepressant agents that act on peripheral tissuesPrincipal Investigator
- Principal Investigator
  
  中島健輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki International University
Development of prophylactic and antidepressant agents that target the BDNF expression in peripheral tissuesPrincipal Investigator
- Principal Investigator
  
  Nakajima Kensuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagasaki International University
Identifying food substances with a BDNF-upregulating effect in peripheral tissues for use in the development of new antidepressantsPrincipal Investigator
- Principal Investigator
  
  Nakajima Kensuke
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Nagasaki International University
Inhibitory effect of natural compounds with carboxylic group on active ghrelin productionPrincipal Investigator
- Principal Investigator
  
  Nakajima Kensuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagasaki International University

All 2024 2023 2022 2021 2020 2017 2016 2015

All Journal Article Presentation

[Journal Article] Upregulation Effect of Citrus Species on Brain-Derived Neurotrophic Factor2024
- Author(s)
  Nakajima K, Han A, Kayano A, Oiso S.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 70 Issue: 1 Pages: 61-71
- DOI
  10.3177/jnsv.70.61
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2024-02-29
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11843
[Journal Article] Upregulation of brain-derived neurotrophic factor by Shiikuwasha (Citrus depressa Hayata)2023
- Author(s)
  Nakajima K, Okubo S, Ohta T, Uto T, Oiso S.
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 9 Issue: 1 Pages: 40-40
- DOI
  10.1186/s40780-023-00309-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11843
[Journal Article] Increasing Effect of Citrus natsudaidai on Brain-Derived Neurotrophic Factor2023
- Author(s)
 Kensuke Nakajima, Shinya Okubo, Shigeru Oiso
- Journal Title
 
 J. Oleo Sci.
 
 Volume: 72 Issue: 2 Pages: 245-255
- DOI
 10.5650/jos.ess22324
- ISSN
 1345-8957, 1347-3352
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-22K11843
[Journal Article] Upregulating Effect of Wheat on Brain-Derived Neurotrophic Factor in Human Lung Adenocarcinoma A549 Cells2021
- Author(s)
  Kensuke Nakajima, Shigeru Oiso
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 70 Issue: 6 Pages: 867-874
- DOI
  10.5650/jos.ess20327
- NAID
  130008046372
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20134
[Journal Article] Identification of traditional Japanese Kampo medicines and crude drugs that upregulate brain-derived neurotrophic factor in human peripheral cells2021
- Author(s)
  Kensuke Nakajima, Shinya Okubo, Shigeru Oiso
- Journal Title
  
  Acta Neurobiol. Exp.
  
  Volume: 81 Pages: 393-404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20134
[Journal Article] Brain-Derived Neurotrophic Factor Up-Regulation by the Methanol Extract of Foxtail Millet in Human Peripheral Cells2020
- Author(s)
  Kensuke Nakajima, Shigeru Oiso, Hiroko Kariyazono
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 66 Issue: 3 Pages: 284-288
- DOI
  10.3177/jnsv.66.284
- NAID
  130007866400
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2020-06-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20134
[Journal Article] Bioactivities of Eriobotrya japonica (Thunb.) Lindl. Leaf and Its Triterpenes2017
- Author(s)
  Uto T, Tung NH, Nakajima K, Ohta T, Oiso S, Kariyazono H, Shoyama Y
- Journal Title
  
  Journal of Pharmacognosy and Natural Products
  
  Volume: 印刷中 Issue: 01 Pages: 134-134
- DOI
  10.4172/2472-0992.1000134
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06805, KAKENHI-PROJECT-16K01848
[Journal Article] Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells 2016
- Author(s)
 Nakajima K, Oiso S, Uto T, Morinaga O, Shoyama Y, Kariyazono H.
- Journal Title
 
 Biomed. Res.
 
 Volume: 37 Issue: 6 Pages: 343-349
- DOI
 10.2220/biomedres.37.343
- NAID
 130005290642
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-15H06805, KAKENHI-PROJECT-16K01848
[Journal Article] グレリン分泌抑制成分探索のための細胞評価系の構築と成分探索2016
- Author(s)
  仮屋薗　博子、大磯　茂、中島　健輔
- Journal Title
  
  Foods and Food Ingredients Journal of Japan
  
  Volume: 221 Pages: 88-93
- Data Source
  KAKENHI-PROJECT-15H06805
[Journal Article] Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production2015
- Author(s)
  Oiso S, Nobe M, Iwasaki S, Nii W, Goto N, Seki Y, Nakajima K, Nakamura K, Kariyazono H.
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 64 Issue: 11 Pages: 1185-1192
- DOI
  10.5650/jos.ess15137
- NAID
  130005105693
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06805, KAKENHI-PROJECT-25350169
[Presentation] 中枢性疾患薬シーズの発見を目指したミカン区カンキツのBDNF産生促進効果の検討2024
- Author(s)
  井手上愛海、中島健輔、大磯茂
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] BDNF産生促進効果を有するハーブの探索2024
- Author(s)
  茅野有沙、中島健輔、大磯茂
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 甘夏ならびに甘夏近縁品種カンキツを基原とする和漢薬のBDNF産生促進効果2023
- Author(s)
  中島健輔、矢崎央隆、大磯茂
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] BDNF産生促進効果を有する和漢薬の探索2023
- Author(s)
  中島健輔、矢崎央隆、大磯茂
- Organizer
  第40回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] シークヮーサー果皮のBDNF産生促進作用2023
- Author(s)
  目良知幹、中島健輔、大磯茂
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 新規抗うつ薬シーズの発見を目指した南西諸島カンキツ未利用部位のBDNF産生促進効果の検討2023
- Author(s)
  別府美鈴、ハンアルム、中島健輔、大磯茂
- Organizer
  第40回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 九州・沖縄特産カンキツのBDNF産生促進効果2023
- Author(s)
  中島健輔、ハンアルム、大磯茂
- Organizer
  2023年度日本栄養・食糧学会九州・沖縄支部および日本家政学会九州支部第67回合同大会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 中枢性疾患薬シーズの発見を目指した摘果南西諸島カンキツのBDNF産生促進効果2023
- Author(s)
  中島健輔、ハンアルム、大磯茂
- Organizer
  第82回九州山口薬学大会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 食によるうつ病の予防・改善を目指したBDNF産生促進食材の探索2023
- Author(s)
  中島健輔、大磯茂
- Organizer
  第21回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 沖縄在来カンキツのBDNF産生促進効果2022
- Author(s)
  中島健輔、大久保伸哉、大磯茂
- Organizer
  第39回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 脳由来神経栄養因子産生促進を機序とする新規抗うつ物質の探索に向けたin vitro評価系の構築2022
- Author(s)
  中島健輔、大久保伸哉、大磯茂
- Organizer
  第3回長崎県薬剤師学術大会（長崎）
- Data Source
  KAKENHI-PROJECT-19K20134
[Presentation] 末梢組織由来細胞における柑橘類の脳由来神経栄養因子産生促進効果2022
- Author(s)
  中島健輔、大久保伸哉、大磯茂
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] 末梢組織由来細胞における柑橘類の脳由来神経栄養因子産生促進効果2022
- Author(s)
  中島健輔、大久保伸哉、大磯茂
- Organizer
  第76回日本栄養・食糧学会大会（神戸）
- Data Source
  KAKENHI-PROJECT-19K20134
[Presentation] 中枢性疾患の予防・改善を目指した脳由来神経栄養因子産生促進食材の探索2022
- Author(s)
  中島健輔、大久保伸哉、大磯茂
- Organizer
  第20回日本機能性食品医用学会総会
- Data Source
  KAKENHI-PROJECT-22K11843
[Presentation] ヒト肺がん細胞における未精製小麦の脳由来神経栄養因子産生促進効果2021
- Author(s)
  中島健輔、大磯茂
- Organizer
  第75回日本・栄養食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K20134
[Presentation] 末梢組織におけるBDNF産生促進作用を機序とする抗うつ食品素材の探索2020
- Author(s)
  中島健輔、大磯茂、仮屋薗博子
- Organizer
  日本農芸化学会2020年度大会(福岡)
- Data Source
  KAKENHI-PROJECT-19K20134
[Presentation] エピガロカテキン没食子酸のオクタノイルグレリン産生抑制効果とその抑制機序の検討2017
- Author(s)
  中島　健輔、大磯　茂、仮屋薗　博子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15H06805
[Presentation] マウス血漿中オクタノイルグレリン濃度に及ぼすエピガロカテキン没食子酸およびグリチルリチン酸の影響2016
- Author(s)
  中島　健輔、大磯　茂、宇都　拓洋、森永　紀、正山　征洋、仮屋薗　博子
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15H06805
[Presentation] 活性型グレリン産生抑制作用を有する天然化合物の探索2016
- Author(s)
  中島　健輔、大磯　茂、宇都　拓洋、森永　紀、正山　征洋、仮屋薗　博子
- Organizer
  平成28年度物理化学インターカレッジセミナー兼日本油化学会界面科学部会九州地区講演会
- Place of Presentation
  福岡
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15H06805
[Presentation] 活性型グレリン産生抑制作用を有する天然化合物の探索2015
- Author(s)
  中島健輔
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15H06805

1. KARIYAZONO hiroko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. OISO shigeru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakajima Kensuke 中島 健輔

Research Projects

Research Products

Co-Researchers

Assessing the potential of citrus as novel antidepressant drug seeds and food supplements acting on peripheral tissuesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of citrus-based prophylactic and antidepressant agents that act on peripheral tissuesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of prophylactic and antidepressant agents that target the BDNF expression in peripheral tissuesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identifying food substances with a BDNF-upregulating effect in peripheral tissues for use in the development of new antidepressantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibitory effect of natural compounds with carboxylic group on active ghrelin productionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Upregulation Effect of Citrus Species on Brain-Derived Neurotrophic Factor2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Upregulation of brain-derived neurotrophic factor by Shiikuwasha (Citrus depressa Hayata)2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increasing Effect of <i>Citrus natsudaidai</i> on Brain-Derived Neurotrophic Factor2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Upregulating Effect of Wheat on Brain-Derived Neurotrophic Factor in Human Lung Adenocarcinoma A549 Cells2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Identification of traditional Japanese Kampo medicines and crude drugs that upregulate brain-derived neurotrophic factor in human peripheral cells2021

Author(s)

Journal Title

Data Source

[Journal Article] Brain-Derived Neurotrophic Factor Up-Regulation by the Methanol Extract of Foxtail Millet in Human Peripheral Cells2020

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Bioactivities of Eriobotrya japonica (Thunb.) Lindl. Leaf and Its Triterpenes2017

Author(s)

Journal Title

DOI

Data Source

Nakajima Kensuke 中島健輔