Matsuo Kazuya 松尾和哉

Researcher Number	90764952
Other IDs
Affiliation (Current)	2025: 京都工芸繊維大学, 分子化学系, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 京都工芸繊維大学, 分子化学系, 助教 2019 – 2021: 北海道大学, 電子科学研究所, 助教 2016 – 2017: 北海道大学, 電子科学研究所, 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Complex systems / Basic Section 37030:Chemical biology-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Biomolecular chemistry Except Principal Investigator Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
Keywords	Principal Investigator 光スイッチ / 光薬理学 / 光異性化 / 超硫黄 / オルガネラ / CENP-E / 光制御型阻害剤 / 光異性化反応 / 細胞分裂 / 阻害剤 … More / 化学修飾 / モータータンパク質 / 光応答性 / ケージド / 光 / 光制御 / 光薬理学リガンド / コバレントドラッグ / 光機能化 / 光化学 / 近接効果 / 部位特異的 / 超硫黄化 / チオール / 光ケージド / 超硫黄種 / センサー / HDAC / 分子内反応 / 酵素反応 / スマートドラッグ / 分子内転位反応 / リガンド / 熱異性化 / 光制御型リガンド / 光・熱異性化 / リガンド結合・解離 / ROCK / 光操作 / 細胞質分裂 / 細胞核分裂 / 染色体 / 外部刺激 / ラベル化 / タンパク質間相互作用 / 反応性スイッチング / アフィニティラベル / 微小管 / キネシン … More Except Principal Investigator 細胞骨格 / マルチスケールイメージング / 染色体 / 光制御 / ゼブラフィッシュ / 細胞分裂 Less

Development of chemical tools for the precise photocontrol of cell divisionPrincipal Investigator
- Principal Investigator
  
  松尾和哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto Institute of Technology
Photoresponsive scavengers for supersulfides in specific organellePrincipal Investigator
- Principal Investigator
  
  松尾和哉
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto Institute of Technology
Development of photocaged reagents for specific persulfidationPrincipal Investigator
- Principal Investigator
  
  松尾和哉
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto Institute of Technology
Chemical construction of a photoreactive protein using a photopharmacological ligandPrincipal Investigator
- Principal Investigator
  
  松尾和哉
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto Institute of Technology
Development of smart drugs for the sensing and inhibition of target biomoleculesPrincipal Investigator
- Principal Investigator
  
  Matsuo Kazuya
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto Institute of Technology
Molecular movies for protein-ligand association and dissociationPrincipal Investigator
- Principal Investigator
  
  松尾和哉
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto Institute of Technology
  Hokkaido University
Development of photocontrol techniques for cell division driven by motor proteinsPrincipal Investigator
- Principal Investigator
  
  Matsuo Kazuya
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Hokkaido University
Principle of body malfunctioning through local cell division failure
- Principal Investigator
  
  Uehara Ryota
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Hokkaido University
Novel chemical protein labeling approach for analyzing the intracellular cargo transport system in kinesinPrincipal Investigator
- Principal Investigator
  
  Matsuo Kazuya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Wash-free FISH of bacterial ribosomal RNAs by benzo[a]pyrene-modified oligonucleotides.2024
- Author(s)
  Y. Watari, K. Nakatani, K. Matsuo, T. Waku, A. Kobori
- Journal Title
  
  Results in Chemistry
  
  Volume: 7 Pages: 101214-101214
- DOI
  10.1016/j.rechem.2023.101214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05307, KAKENHI-PUBLICLY-22H04750, KAKENHI-PUBLICLY-22H05566
[Journal Article] Tetraploidy-linked sensitization to CENP-E inhibition in human cells.2023
- Author(s)
  Yoshizawa Koya、Matsura Akira、Shimada Masaya、Ishida‐Ishihara Sumire、Sato Fuyu、Yamamoto Takahiro、Yaguchi Kan、Kawamoto Eiji、Kuroda Taruho、Matsuo Kazuya、Tamaoki Nobuyuki、Sakai Ryuichi、Shimada Yasuhito、Mishra Mithilesh、Uehara Ryota
- Journal Title
  
  Molecular Oncology
  
  Volume: 10 Issue: 6 Pages: 13379-13379
- DOI
  10.1002/1878-0261.13379
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09015, KAKENHI-PROJECT-21K09070, KAKENHI-PROJECT-22K09117, KAKENHI-PROJECT-19KK0181, KAKENHI-PROJECT-19KK0224, KAKENHI-PROJECT-21K19244, KAKENHI-PUBLICLY-22H04750
[Journal Article] Photopharmacological Tools for Mitotic Cell Division2022
- Author(s)
  Matsuo Kazuya
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 142 Issue: 5 Pages: 513-519
- DOI
  10.1248/yakushi.21-00203-5
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2022-05-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05432, KAKENHI-PUBLICLY-22H04750
[Journal Article] Rational design and development of a lit-active photoswitchable inhibitor targeting CENP-E2021
- Author(s)
  Matsuo Kazuya、Tamaoki Nobuyuki
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 19 Issue: 32 Pages: 6979-6984
- DOI
  10.1039/d1ob01332g
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H05432, KAKENHI-PROJECT-19KK0181
[Journal Article] A visible light-controllable Rho kinase inhibitor based on a photochromic phenylazothiazole2021
- Author(s)
  Matsuo Kazuya、Thayyil Sampreeth、Kawaguchi Mitsuyasu、Nakagawa Hidehiko、Tamaoki Nobuyuki
- Journal Title
  
  Chemical Communications
  
  Volume: 57 Issue: 93 Pages: 12500-12503
- DOI
  10.1039/d1cc04905d
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H05432, KAKENHI-PUBLICLY-21H00290, KAKENHI-PROJECT-21K19317, KAKENHI-PROJECT-19KK0181
[Journal Article] Photoswitchable CENP-E Inhibitor Enabling the Dynamic Control of Chromosome Movement and Mitotic Progression2020
- Author(s)
  Noushaba Nusrat Mafy, Kazuya Matsuo, Shota Hiruma, Ryota Uehara, Nobuyuki Tamaoki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Issue: 4 Pages: 1763-1767
- DOI
  10.1021/jacs.9b12782
- NAID
  120006955185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15709, KAKENHI-PROJECT-19KK0181, KAKENHI-PUBLICLY-19H05413, KAKENHI-PROJECT-18H02042, KAKENHI-PROJECT-19H03219
[Journal Article] Structure-property relationships of photoresponsive inhibitors of the kinesin motor2016
- Author(s)
  Ammathnadu S. Amrutha, K. R. Sunil Kumar, Kazuya Matsuo, Nobuyuki Tamaoki
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14 Issue: 30 Pages: 7202-7210
- DOI
  10.1039/c6ob00951d
- NAID
  120005851050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] ケミカルツールによる細胞機能の光操作2024
- Author(s)
  松尾和哉
- Organizer
  薬学会第１４４年会薬学における生命指向型化学
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] ケミカルツールによる細胞機能の光操作2024
- Author(s)
  松尾和哉
- Organizer
  薬学会第１４４年会　薬学における生命指向型化学
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05566
[Presentation] コバレントに機能する光制御型CENP-E阻害剤を用いた細胞分裂制御2023
- Author(s)
  松尾和哉、山岡秀介、和久友則、小堀哲生
- Organizer
  日本化学会　第103春季年会
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 細胞機能を光操作する分子技術2023
- Author(s)
  松尾和哉
- Organizer
  令和５年度純正・応用化学セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05566
[Presentation] The influence of aberrant mitosis in different developmental stages in zebrafish embryos2023
- Author(s)
  松浦暉、松尾和哉、小谷友也、玉置信之、上原亮太
- Organizer
  第56回日本発生生物学会
- Data Source
  KAKENHI-PROJECT-19KK0181
[Presentation] 細胞機能を光操作する分子技術2023
- Author(s)
  松尾和哉
- Organizer
  令和５年度純正・応用化学セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 細胞分裂の光操作技術2023
- Author(s)
  松尾和哉
- Organizer
  分子夾雑に挑む化学＠わかやま
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 細胞分裂の光操作技術2023
- Author(s)
  松尾和哉
- Organizer
  分子夾雑に挑む化学＠わかやま
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05566
[Presentation] 細胞機能を操作する光化学技術の開発2022
- Author(s)
  松尾和哉
- Organizer
  第27回光科学若手研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19317
[Presentation] 細胞機能を操作する光薬理学ツールの開発2022
- Author(s)
  松尾和哉
- Organizer
  第45回日本分子生物学会年会ワークショップ
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 細胞機能を操作する光化学技術の開発2022
- Author(s)
  松尾和哉
- Organizer
  第２７回光科学若手研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05566
[Presentation] アクトミオシン系を可視光で制御できるROCK阻害剤の開発2022
- Author(s)
  松尾和哉、和久友則、小堀哲生
- Organizer
  第12回4大学連携研究フォーラム
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 光制御型CENP-E阻害剤を基盤としたコバレントドラッグへの展開2022
- Author(s)
  松尾和哉
- Organizer
  令和４年度　新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 部位特異的な超硫黄化法の開発2022
- Author(s)
  松尾和哉
- Organizer
  新興硫黄生物学が拓く生命原理変革(硫黄生物学) 第 2 回領域会議
- Data Source
  KAKENHI-PUBLICLY-22H05566
[Presentation] 細胞分裂を標的とした光制御型コバレントドラッグの開発2022
- Author(s)
  山岡秀介、松尾和哉、和久友則、小堀哲生
- Organizer
  第12回4大学連携研究フォーラム
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 細胞機能を操作する光化学技術の開発2022
- Author(s)
  松尾和哉
- Organizer
  第27回光科学若手研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04750
[Presentation] 細胞分裂を操作する光薬理学ツール2021
- Author(s)
  松尾和哉
- Organizer
  日本薬学会第141年会（広島）
- Invited
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] 可視光による分裂期染色体の光操作法2021
- Author(s)
  松尾和哉、上原亮太、菊川峰志、玉置信之
- Organizer
  第15回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PUBLICLY-20H05432
[Presentation] 光制御型ROCK阻害剤の開発2021
- Author(s)
  松尾和哉
- Organizer
  令和3年度　新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PUBLICLY-20H05432
[Presentation] Photopharmacological Approaches for Mitotic Cell Division2021
- Author(s)
  Kazuya Matsuo
- Organizer
  2021 RIES-CEFMS on-line symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05432
[Presentation] 細胞分裂を操作する光薬理学ツール2021
- Author(s)
  松尾和哉
- Organizer
  日本薬学会第141年会（広島）
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05432
[Presentation] 染色体の動きを光操作するケミカルツールの開発2020
- Author(s)
  松尾和哉
- Organizer
  令和二年度新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PUBLICLY-20H05432
[Presentation] モータータンパク質が駆動する分裂期染色体の光操作2020
- Author(s)
  松尾和哉・Noushaba N. Mafy・比留間翔太・上原亮太・玉置信之
- Organizer
  第14回バイオ関連化学シンポジウム2020（オンライン開催）
- Data Source
  KAKENHI-PUBLICLY-20H05432
[Presentation] モータータンパク質が駆動する分裂期染色体の光操作2020
- Author(s)
  松尾和哉、Noushaba N. Mafy、比留間翔太、上原亮太、玉置信之
- Organizer
  第14回バイオ関連化学シンポジウム2020（オンライン開催）
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] 分裂期染色体の光操作2019
- Author(s)
  松尾和哉、Mafy Nusrat Noushaba、比留間翔太、上原亮太、玉置信之
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] 「動く」タンパク質を標的とした光化学技術戦略とその展開2019
- Author(s)
  松尾和哉
- Organizer
  2019年度北海道高分子若手研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] Development of the photoswitchable mitotic inhibitor2019
- Author(s)
  Kazuya Matsuo, Mafy Nusrat Noushaba, Shota Hiruma, Ryota Uehara, Nobuyuki Tamaoki
- Organizer
  The 20th RIES-HOKUDAI International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] Optochemical Motion Control for Biomachines Under Live Cell Condition2019
- Author(s)
  Kazuya Matsuo
- Organizer
  ICPAC Yangon 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] A photoswitchable inhibitor for the mitotic motor protein2019
- Author(s)
  Kazuya Matsuo, Mafy Nusrat Noushaba, Shota Hiruma, Ryota Uehara, Nobuyuki Tamaoki
- Organizer
  Cold Spring Harbor Asia, Chemical Biology and Drug Discovery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] 細胞分裂のオプトケミカルコントロール2019
- Author(s)
  松尾和哉、Mafy Nusrat Noushaba、比留間翔太、上原亮太、玉置信之
- Organizer
  第13回バイオ関連化学シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19K15709
[Presentation] ケミカルエンジニアリングによるモータータンパク質の機能改変2018
- Author(s)
  松尾和哉、玉置信之
- Organizer
  第3回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] アフィニティ駆動型化学修飾を利用した光制御型キネシンの開発2018
- Author(s)
  松尾和哉、玉置信之
- Organizer
  日本薬学会　第138年会
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] 化学修飾による光応答性モータータンパク質の構築2017
- Author(s)
  松尾和哉、玉置信之
- Organizer
  第5回アライアンス若手研究交流会
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] A Reversibly Photoswitchable Biomachine Constructed by Chemical Protein Engineering2017
- Author(s)
  Kazuya Matsuo, Nobuyuki Tamaoki
- Organizer
  The 18th RIES-HOKUDAI INTERNATIONAL SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] 可逆的に光制御できるキネシン阻害剤の開発とその応用2017
- Author(s)
  松尾和哉、玉置信之
- Organizer
  日本化学会　第97回春季年会
- Place of Presentation
  慶応義塾大学日吉キャンパス（神奈川県横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] 新規アゾベンゼン三リン酸によるキネシンの駆動とin vitro光制御2017
- Author(s)
  芦野史弥、松尾和哉、玉置信之
- Organizer
  日本化学会　第97回春季年会
- Place of Presentation
  慶応義塾大学日吉キャンパス（神奈川県横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] Structure-Activity Relationship of Photochromic Inhibitors for Kinesin-12016
- Author(s)
  Kazuya Matsuo, Nobuyuki Tamaoki
- Organizer
  HOKUDAI-NCTU Joint Symposium on Nano, Photo and Bio Sciences in 2016
- Place of Presentation
  Hokkaido University, Sapporo, Hokkaido
- Year and Date
  2016-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] Rational Design of Potent Photoreversible Kinesin-1 Inhibitors2016
- Author(s)
  Kazuya Matsuo, Nobuyuki Tamaoki
- Organizer
  The 17th RIES-Hokudai International Symposium
- Place of Presentation
  Chasseresse Gateaux Kingdom, Sapporo, Hokkaido
- Year and Date
  2016-12-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16635
[Presentation] モータータンパク質キネシンの光制御型阻害剤における構造活性相関2016
- Author(s)
  松尾和哉、玉置信之
- Organizer
  第4回アライアンス若手研究交流会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2016-11-09
- Data Source
  KAKENHI-PROJECT-16K16635

1. Uehara Ryota (20580020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 塚田祐基 (80580000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KAWAMOTO Eiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小堀哲生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsuo Kazuya 松尾 和哉

Research Projects

Research Products

Co-Researchers

Development of chemical tools for the precise photocontrol of cell divisionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Photoresponsive scavengers for supersulfides in specific organellePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of photocaged reagents for specific persulfidationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemical construction of a photoreactive protein using a photopharmacological ligandPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of smart drugs for the sensing and inhibition of target biomoleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular movies for protein-ligand association and dissociationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of photocontrol techniques for cell division driven by motor proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principle of body malfunctioning through local cell division failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel chemical protein labeling approach for analyzing the intracellular cargo transport system in kinesinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Wash-free FISH of bacterial ribosomal RNAs by benzo[a]pyrene-modified oligonucleotides.2024

Author(s)

Journal Title

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[Journal Article] Tetraploidy-linked sensitization to CENP-E inhibition in human cells.2023

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[Journal Article] Photopharmacological Tools for Mitotic Cell Division2022

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[Journal Article] Rational design and development of a lit-active photoswitchable inhibitor targeting CENP-E2021

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Matsuo Kazuya 松尾和哉