Sonobe Shota 園部奨太

Researcher Number	90771808
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2017 – 2024: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55060:Emergency medicine-related / Emergency medicine
Keywords	Principal Investigator ARDS / Setdb2 / エピジェネティクス / AKI / 急性腎障害 / 血管内皮細胞 / 急性呼吸促拍症候群 / ヒストンメチル化 / SETDB2 / 急性呼吸促迫症候群

The mechanism of vascular endothelial cells apoptosis derived from histone methyltransferase SETDB2Principal Investigator
- Principal Investigator
  
  園部奨太
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nara Medical University
Investigation of ARDS molecular mechanism throw vascular entohelial cells - Histon methyltransferase protein SETDB2 -Principal Investigator
- Principal Investigator
  
  SONOBE SHOTA
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nara Medical University
The role and clinical significance of histone methylation enzyme Setdb2 in ARDSPrincipal Investigator
- Principal Investigator
  
  Sonobe Shota
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Nara Medical University

All 2023 2021 2019 2018

All Journal Article Presentation

[Journal Article] A Disintegrin and Metalloproteinase with Thrombospondin Motifs 4 Regulates Pulmonary Vascular Hyperpermeability through Destruction of Glycocalyx in Acute Respiratory Distress Syndrome2023
- Author(s)
  Konda Makiko、Kitabatake Masahiro、Ouji-Sageshima Noriko、Tonomura Rei、Furukawa Ryutaro、Sonobe Shota、Terada-Ikeda Chiyoko、Takeda Maiko、Kawaguchi Masahiko、Ito Toshihiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 22 Pages: 16230-16230
- DOI
  10.3390/ijms242216230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09310, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
[Journal Article] The critical role of the histone modification enzyme SETDB2 in the pathogenesis of acute respiratory distress syndrome2023
- Author(s)
  Sonobe Shota、Kitabatake Masahiro、Hara Atsushi、Konda Makiko、Ouji-Sageshima Noriko、Terada-Ikeda Chiyoko、Furukawa Ryutaro、Imakita Natsuko、Oda Akihisa、Takeda Maiko、Takamura Shiki、Inoue Satoki、Kunkel Steven L.、Kawaguchi Masahiko、Ito Toshihiro
- Journal Title
  
  Shock
  
  Volume: 60 Issue: 1 Pages: 137-145
- DOI
  10.1097/shk.0000000000002145
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15374, KAKENHI-PROJECT-20K09310, KAKENHI-PROJECT-21K07825, KAKENHI-PROJECT-21K08162, KAKENHI-PROJECT-20K17469, KAKENHI-PROJECT-23K27431
[Journal Article] A pediatric case developing critical abdominal distension caused by a combination of humidified high-flow nasal cannula oxygen therapy and nasal airway.2018
- Author(s)
  Satoki Inoue, Yumiko Tamaki, Shota Sonobe, Junji Egawa Masahiko Kawaguchi
- Journal Title
  
  JA Clinical Reports
  
  Volume: 4(1) Issue: 1 Pages: 4-4
- DOI
  10.1186/s40981-017-0143-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17065
[Presentation] Histone modification enzyme SET domain bifurcated 2 (Setdb2) contributes to the pathogenesisloss in vascular endothelial cells leads ofto exacerbation of acute respiratory distress syndrome (ARDS) in murine model.2021
- Author(s)
  Shota Sonobe
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09310
[Presentation] エピジェネティクス解析を用いた急性呼吸促迫症候群（ARDS）の病態解明2019
- Author(s)
  園部奨太
- Organizer
  第46回日本集中治療医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K17065
[Presentation] Histone modification enzyme SET domain bifurcated 2 (Setdb2) regulates acute inflammation in murine model of acute respiratory distress syndrome (ARDS).2019
- Author(s)
  Shota Sonobe, Masahiro Kitabatake, Ryutaro Furukawa, Tomoko Nishimura, Noriko Ouji-Sagaeshima, Toshihiro Ito
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K17065
[Presentation] The critical role of Epigenetic regulation by Setdb2 in acute respiratory distress syndrome (ARDS) model2018
- Author(s)
  Shota Sonobe, Masahiro Kitabatake, Noriko Ouji-sageshima, Natsuko Imakita, Toshihiro Ito
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K17065
[Presentation] Examination of sternotomy range that causes respiratory failure2018
- Author(s)
  Shota Sonobe, Satoki Inoue, Junji Egawa, Masahiko Kawaguchi
- Organizer
  日本集中治療医学会
- Data Source
  KAKENHI-PROJECT-17K17065

1. 北畠正大 (60457588)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 小田朗永 (80547703)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 今北菜津子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sonobe Shota 園部 奨太

Research Projects

Research Products

Co-Researchers

The mechanism of vascular endothelial cells apoptosis derived from histone methyltransferase SETDB2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of ARDS molecular mechanism throw vascular entohelial cells - Histon methyltransferase protein SETDB2 -Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role and clinical significance of histone methylation enzyme Setdb2 in ARDSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A Disintegrin and Metalloproteinase with Thrombospondin Motifs 4 Regulates Pulmonary Vascular Hyperpermeability through Destruction of Glycocalyx in Acute Respiratory Distress Syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The critical role of the histone modification enzyme SETDB2 in the pathogenesis of acute respiratory distress syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A pediatric case developing critical abdominal distension caused by a combination of humidified high-flow nasal cannula oxygen therapy and nasal airway.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Histone modification enzyme SET domain bifurcated 2 (Setdb2) contributes to the pathogenesisloss in vascular endothelial cells leads ofto exacerbation of acute respiratory distress syndrome (ARDS) in murine model.2021

Author(s)

Organizer

Data Source

[Presentation] エピジェネティクス解析を用いた急性呼吸促迫症候群（ARDS）の病態解明2019

Author(s)

Organizer

Data Source

[Presentation] Histone modification enzyme SET domain bifurcated 2 (Setdb2) regulates acute inflammation in murine model of acute respiratory distress syndrome (ARDS).2019

Author(s)

Organizer

Data Source

[Presentation] The critical role of Epigenetic regulation by Setdb2 in acute respiratory distress syndrome (ARDS) model2018

Author(s)

Organizer

Data Source

[Presentation] Examination of sternotomy range that causes respiratory failure2018

Author(s)

Organizer

Data Source

Sonobe Shota 園部奨太