Hirasawa Kazuhiro 平澤一浩

… Alternative Names

平澤一浩ヒラサワカズヒロ

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Researcher Number	90772161
Affiliation (Current)	2025: 東京医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2016 – 2018: 東京医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Applied pharmacology
Keywords	Principal Investigator 分子標的治療 / 薬物治療学 / ＥＧＦＲ　ＴＫＩ / アミノ酸トランスポーター / マクロライド系抗菌薬 / 分子標的薬 / マクロライド抗生剤 / がん / ネクロプトーシス / アポトーシス … More / 頭頸部腫瘍 / EGFR-TKI / 小胞体ストレス / アミノ酸 / オートファジー / マクロライド抗菌薬 / 頭頸部癌 Less

Establishment of novel "amino acid starvation induction therapy" using macrolide antibiotics for head and neck cancerPrincipal Investigator
- Principal Investigator
  
  Hirasawa Kazuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tokyo Medical University

All 2018 2016

All Journal Article Presentation

[Journal Article] 嗄声を契機に発見された若年胸部大動脈瘤切迫破裂例2018
- Author(s)
  平澤一浩, 高田大輔, 西山信宏, 塚原清彰
- Journal Title
  
  耳鼻咽喉科臨床
  
  Volume: 111 Pages: 351-355
- NAID
  130006729783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21387
[Journal Article] Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis.2018
- Author(s)
  Saito Y, Moriya S, Kazama H, Hirasawa K, Miyahara K, Kokuba H, Hino H, Kikuchi　H, Takano N, Hiramoto M, Tsukahara K, Miyazawa K.
- Journal Title
  
  Int J Oncol.
  
  Volume: 52 Pages: 1165-1177
- DOI
  10.3892/ijo.2018.4282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08771, KAKENHI-PROJECT-16K19187, KAKENHI-PROJECT-16K21387, KAKENHI-PROJECT-16K21388, KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-17K15031
[Journal Article] Macrolide antibiotics exhibit cytotoxiceffect under amino acid-depleted culture condition by blocking autophagy flux in head and neck squamous cell carcinoma cell lines.2016
- Author(s)
  Hirasawa K, Moriya S, Miyahara K, Kazama H, Hirota A, Takemura J, Abe A, Inazu　M, Hiramoto M, Tsukahara K, Miyazawa K.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 12 Pages: 1848-1858
- DOI
  10.1371/journal.pone.0164529
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460478, KAKENHI-PROJECT-26670589, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K19187, KAKENHI-PROJECT-16K21387, KAKENHI-PROJECT-16K21388
[Journal Article] Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines.2016
- Author(s)
  Miyahara K, Kazama H, Kokuba H, Komatsu S, Hirota A, Takemura J, Hirasawa K,Moriya S, Abe A, Hiramoto M, Ishikawa T, Miyazawa K.
- Journal Title
  
  Int J Oncol.
  
  Volume: 49 Issue: 5 Pages: 1848-1858
- DOI
  10.3892/ijo.2016.3673
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460478, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K19187, KAKENHI-PROJECT-16K21387
[Presentation] 嗄声を契機に発見された若年胸部大動脈瘤切迫破裂例2018
- Author(s)
  平澤一浩
- Organizer
  第80回耳鼻咽喉科臨床学会・学術講演会
- Data Source
  KAKENHI-PROJECT-16K21387
[Presentation] Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition2016
- Author(s)
  Kazuhiro Hirasawa、Shota Moriya、Kana Miyahara、Hiromi Kazama、Ayako Hirota、Jun Yoshida、Akihisa Abe、Masato Inazu、Masaki Hiramoto、Kiyoaki Tsukahara、Keisuke Miyazawa
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K21387

1. MIYAZAWA Keisuke (50209897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. MORIYA Shota (30634935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 平本正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Hirasawa Kazuhiro 平澤 一浩

平澤 一浩 ヒラサワ カズヒロ

Research Projects

Research Products

Co-Researchers

Establishment of novel "amino acid starvation induction therapy" using macrolide antibiotics for head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 嗄声を契機に発見された若年胸部大動脈瘤切迫破裂例2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Macrolide antibiotics exhibit cytotoxiceffect under amino acid-depleted culture condition by blocking autophagy flux in head and neck squamous cell carcinoma cell lines.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 嗄声を契機に発見された若年胸部大動脈瘤切迫破裂例2018

Author(s)

Organizer

Data Source

[Presentation] Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Hirasawa Kazuhiro 平澤一浩

平澤一浩ヒラサワカズヒロ