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Otsuki Sachiko  大月 幸子

ORCIDConnect your ORCID iD *help
Researcher Number 90774018
Affiliation (Current) 2025: 広島大学, 病院(医), 寄附講座助教
Affiliation (based on the past Project Information) *help 2021 – 2023: 広島大学, 医系科学研究科(医), 助教
2020: 広島大学, 病院(医), 助教
2017 – 2018: 広島大学, 病院(医), 助教
2016: 広島大学, 病院(医), 医科診療医
Review Section/Research Field
Principal Investigator
Basic Section 55050:Anesthesiology-related / Anesthesiology
Except Principal Investigator
Basic Section 55050:Anesthesiology-related
Keywords
Principal Investigator
悪性高熱症 / 加齢 / ノックインマウス / CACNA1S / カルシウム拮抗薬 / 細胞内カルシウム濃度 / 筋毒性 / 局所麻酔薬
Except Principal Investigator
NGS / CACNA1S … More / RYR1 / TRPV1 / STAC3 / 遺伝子解析 / 悪性高熱症 Less
  • Research Projects

    (4 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (9 People)
  •  Investigation of the effect of aging on the development of malignant hyperthermia in RYR1 knock-in mouse.Principal Investigator

    • Principal Investigator
      大月 幸子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hiroshima University
  •  悪性高熱症の原因遺伝子としてのSTAC3・TRPV1の関与の探索

    • Principal Investigator
      神崎 理英子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hiroshima University
  •  Investigation of the effect of CACNA1S mutation on intracellular calcium kineticsPrincipal Investigator

    • Principal Investigator
      Otsuki Sachiko
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hiroshima University
  •  Do local anesthetics increase intracelluler calcium concentration?Principal Investigator

    • Principal Investigator
      Otsuki Sachiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology
    • Research Institution
      Hiroshima University

All 2024 2023 2018 2016

All Journal Article Presentation

  • [Journal Article] Rapid dantrolene administration with body temperature monitoring is associated with decreased mortality in Japanese malignant hyperthermia events.2023

    • Author(s)
      Toyota Y, Kondo T, Shorin D, Sumii A, Kido K, Watanabe T, Otsuki S, Kanzaki R, Miyoshi H, Yasuda T, Horikawa YT, Mukaida K, Tsutsumi YM.
    • Journal Title

      BioMed Res Int

      Volume: 2023 Issue: 1 Pages: 8340209-8340209

    • DOI

      10.1155/2023/8340209

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09047, KAKENHI-PROJECT-22K09070, KAKENHI-PROJECT-22K09095
  • [Journal Article] Myotoxicity of local anesthetics is equivalent in individuals with and without predisposition to malignant hyperthermia.2018

    • Author(s)
      Otsuki S, Yasuda T, Mukaida K, Noda Y, Kanzaki R, Miyoshi H, Kondo T, Hamada H, Kawamoto M.
    • Journal Title

      J Anesth.

      Volume: 32 Issue: 4 Pages: 616-618

    • DOI

      10.1007/s00540-018-2526-4

    • NAID

      40021627019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08856, KAKENHI-PROJECT-16K10938, KAKENHI-PROJECT-16K20100
  • [Presentation] Genetic panel testing of malignant hyperthermia patients in Japan2024

    • Author(s)
      Ayako Sumii, Hirotsugu Miyoshi, Keiko Mukaida, Tsuyoshi Ikeda, Kenshiro Kido, Yuko Noda, Toshimichi Yasuda, Sachiko Otsuki, Rieko Kanzaki, Yasuo Tsutsumi
    • Organizer
      18th World Congress of Anaesthesiologists (WCA2024)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09095
  • [Presentation] 悪性高熱症原因遺伝子であるジヒドロピリジン受容体遺伝子の変異R174W機能解析2023

    • Author(s)
      向田 圭子、大月 幸子、野田 祐子、神崎 理英子、三好 寛二、堤 保夫
    • Organizer
      日本麻酔科学会第70回学術集会
    • Data Source
      KAKENHI-PROJECT-22K09095
  • [Presentation] 悪性高熱症素因骨格筋のカルシウム代謝に及ぼすアミド型局所麻酔薬の影響2016

    • Author(s)
      大月幸子
    • Organizer
      日本麻酔科学会
    • Place of Presentation
      神戸ポートピアホテル
    • Data Source
      KAKENHI-PROJECT-16K20100
  • 1.  三好 寛二 (50645364)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  神崎 理英子 (70751402)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  堤 保夫 (90523499)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  Yasuda Toshimichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  Mukaida Keiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Noda Yuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Kondo Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  Hamada Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Kawamoto Masashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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