Ohbayashi Ryudo 大林龍胆

Researcher Number	90778333
Other IDs	https://orcid.org/0000-0001-6359-0122
Affiliation (Current)	2025: 東京都立大学, 理学研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 静岡大学, 理学部, 助教 2019: 東京工業大学, 科学技術創成研究院, 特任助教 2018: 東京大学, 大学院理学系研究科(理学部), 客員共同研究員 2016 – 2017: 国立遺伝学研究所, 細胞遺伝研究系, 博士研究員
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 45010:Genetics-related / Genome biology
Keywords	Principal Investigator シアノバクテリア / ゲノム倍数性 / 進化 / DNA複製 / ゲノム複製 / 葉緑体 / DnaA / 細胞内共生 / ゲノム重複 / 染色体倍数性 … More / ゲノム遺伝 / 遺伝学 / 微生物 / ゲノム / DNAコーミング / 藍藻 / 共生進化 Less

細胞内共生前に獲得したDnaA非依存型ゲノム複製機構とその進化的意義の解明Principal Investigator
- Principal Investigator
  
  大林龍胆
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Shizuoka University
倍数ゲノム複製機構がもたらす新規機能獲得と進化速度の両立Principal Investigator
- Principal Investigator
  
  大林龍胆
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Shizuoka University
ゲノム倍数性がもたらす進化可能性～揺らぎと安定性の両立～Principal Investigator
- Principal Investigator
  
  大林龍胆
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tokyo Institute of Technology
  The University of Tokyo
Analyses of regulation mechanism of DNA replication and its evolutionary significance in cyanobacteria and chloroplastPrincipal Investigator
- Principal Investigator
  
  Ohbayashi Ryudo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Genome biology
- Research Institution
  National Institute of Genetics

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Glycogen deficiency enhances carbon partitioning into glutamate for an alternative extracellular metabolic sink in cyanobacteria2024
- Author(s)
  Kato Yuichi、Hidese Ryota、Matsuda Mami、Ohbayashi Ryudo、Ashida Hiroki、Kondo Akihiko、Hasunuma Tomohisa
- Journal Title
  
  Communications Biology
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s42003-024-05929-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15142
[Journal Article] Discovery of novel replication proteins for large plasmids in cyanobacteria and their potential applications in genetic engineering2024
- Author(s)
  Ohdate Kazuma、Sakata Minori、Maeda Kaisei、Sakamaki Yutaka、Nimura-Matsune Kaori、Ohbayashi Ryudo、Hess Wolfgang R.、Watanabe Satoru
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 15
- DOI
  10.3389/fmicb.2024.1311290
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15142
[Journal Article] ppGpp accumulation reduces the expression of the global nitrogen homeostasis-modulating NtcA regulon by affecting 2-oxoglutarate levels2023
- Author(s)
  Hidese Ryota、Ohbayashi Ryudo、Kato Yuichi、Matsuda Mami、Tanaka Kan、Imamura Sousuke、Ashida Hiroki、Kondo Akihiko、Hasunuma Tomohisa
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 1285-1285
- DOI
  10.1038/s42003-023-05632-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15142, KAKENHI-PROJECT-23K23503
[Journal Article] Evolutionary Innovation by Polyploidy2022
- Author(s)
  Hatakeyama Tetsuhiro S.、Ohbayashi Ryudo
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.10.29.514387
- Data Source
  KAKENHI-PROJECT-21K15142, KAKENHI-PUBLICLY-20H04862
[Journal Article] 細胞増殖に伴うラン藻の複数コピーゲノムの維持機構2021
- Author(s)
  大林龍胆
- Journal Title
  
  Seibutsu-kogaku Kaishi
  
  Volume: 99 Issue: 8 Pages: 425-428
- DOI
  10.34565/seibutsukogaku.99.8_425
- NAID
  130008077604
- ISSN
  0919-3758, 2435-8630
- Year and Date
  2021-08-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-21K15142
[Journal Article] Specific binding of DnaA to the DnaA box motif in the cyanobacterium <i>Synechococcus elongatus</i> PCC 79422020
- Author(s)
  Satoru Watanabe, Shunsuke Saito, Yasuhiro Suezaki, Takeshi Seguchi, Ryudo Ohbayashi
- Journal Title
  
  J. Gen. Appl. Microbiol.
  
  Volume: 66 Issue: 2 Pages: 80-84
- DOI
  10.2323/jgam.2019.11.005
- NAID
  130007855494
- ISSN
  0022-1260, 1349-8037
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05793, KAKENHI-PUBLICLY-18H04827
[Journal Article] Relationship between Cell Cycle and Diel Transcriptomic Changes in Metabolism in a Unicellular Red Alga2020
- Author(s)
  Fujiwara Takayuki、Hirooka Shunsuke、Ohbayashi Ryudo、Onuma Ryo、Miyagishima Shin-ya
- Journal Title
  
  Plant Physiology
  
  Volume: 183 Issue: 4 Pages: 1484-1501
- DOI
  10.1104/pp.20.00469
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06300, KAKENHI-PUBLICLY-20H04862
[Journal Article] Evolutionary Changes in DnaA-Dependent Chromosomal Replication in Cyanobacteria2020
- Author(s)
  Ohbayashi Ryudo、Hirooka Shunsuke、Onuma Ryo、Kanesaki Yu、Hirose Yuu、Kobayashi Yusuke、Fujiwara Takayuki、Furusawa Chikara、Miyagishima Shin-ya
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 11 Pages: 786-786
- DOI
  10.3389/fmicb.2020.00786
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J01993, KAKENHI-PROJECT-18K05416, KAKENHI-PROJECT-18K06300, KAKENHI-PUBLICLY-20H04862, KAKENHI-PUBLICLY-18H04827
[Journal Article] Integration of a Galdieria plasma membrane sugar transporter enables heterotrophic growth of the obligate photoautotrophic red alga Cynanidioschyzon merolae2019
- Author(s)
  Fujiwara Takayuki、Hirooka Shunsuke、Mukai Mizuna、Ohbayashi Ryudo、kanesaki Yu、Watanabe Satoru、Miyagishima Shin-ya
- Journal Title
  
  Plant Direct
  
  Volume: 3 Issue: 4
- DOI
  10.1002/pld3.134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06300, KAKENHI-PROJECT-17H01446, KAKENHI-PUBLICLY-18H04827
[Journal Article] Coordination of Polyploid Chromosome Replication With Cell Size and Growth in a Cyanobacterium.2019
- Author(s)
  Ohbayashi R, Nakamachi A, Hatakeyama TS, Watanabe S, Kanesaki Y, Chibazakura T, Yoshikawa H, Miyagishima SY.
- Journal Title
  
  mBio
  
  Volume: 10 Issue: 2
- DOI
  10.1128/mbio.00510-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05416, KAKENHI-PROJECT-18K06300, KAKENHI-PUBLICLY-18H04827
[Journal Article] Direct Visualization of the Multicopy Chromosomes in Cyanobacterium Synechococcus elongatus PCC 79422018
- Author(s)
  Ohbayashi Ryudo、Yoshikawa Hirofumi、Watanabe Satoru
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 8 Issue: 15
- DOI
  10.21769/bioprotoc.2958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Journal Article] ParA-like protein influences the distribution of multi-copy chromosomes in cyanobacterium Synechococcus elongatus PCC 7942.2018
- Author(s)
  Watanabe S, Noda A, Ohbayashi R, Uchioke K, Kurihara A, Nakatake S, Morioka S, Kanesaki Y, Chibazakura T, Yoshikawa H
- Journal Title
  
  Microbiology
  
  Volume: 164 Issue: 1 Pages: 45-56
- DOI
  10.1099/mic.0.000577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07675, KAKENHI-PROJECT-16H07418, KAKENHI-PROJECT-15K07368, KAKENHI-PROJECT-15K07557, KAKENHI-PUBLICLY-17H05451
[Journal Article] Development of a double nuclear gene-targeting method by two-step transformation based on a newly established chloramphenicol-selection system in the red alga Cyanidioschyzon merolae2017
- Author(s)
  Fujiwara, T., Ohnuma, M., Kuroiwa, T., Ohbayashi, R., Hirooka, S.and Miyagishima, S.
- Journal Title
  
  Front. Plant Sci.
  
  Volume: 8 Pages: 343-343
- DOI
  10.3389/fpls.2017.00343
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25251039, KAKENHI-PROJECT-17K00676, KAKENHI-PROJECT-16H04813, KAKENHI-PROJECT-16H07418, KAKENHI-PROJECT-16K14791, KAKENHI-PROJECT-15K18588
[Journal Article] Variety of DNA Replication Activity Among Cyanobacteria Correlates with Distinct Respiration Activity in the Dark2017
- Author(s)
  Ryudo Ohbayashi, Jun-ya Yamamoto, Satoru Watanabe, Yu Kanesaki, Taku Chibazakura, Shin-ya Miyagishima, Hirofumi Yoshikawa
- Journal Title
  
  Plant and Cell Physiology
  
  Volume: 58 (2) Pages: 279-286
- DOI
  10.1093/pcp/pcw186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07418, KAKENHI-PROJECT-15K07368, KAKENHI-PROJECT-15K07557
[Journal Article] Acidophilic green algal genome provides insights into adaptation to an acidic environment2017
- Author(s)
  Hirooka, S., Hirose, Y., Kanesaki, Y., Higuchi, S., Fujiwara, T., Onuma, R., Era, A., Ohbayashi, R., Uzuka, A., Nozaki, H., Yoshikawa, H., and Miyagishima, S.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 114 Issue: 39
- DOI
  10.1073/pnas.1707072114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01446, KAKENHI-PROJECT-16H07418, KAKENHI-PROJECT-15K07368, KAKENHI-PROJECT-15K18588, KAKENHI-PROJECT-16H02518
[Patent] アミノ酸および/または有機酸を製造する方法2022
- Inventor(s)
  蓮沼誠久、加藤悠一、秀瀬涼太、蘆田弘樹、大林龍胆
- Industrial Property Rights Holder
  蓮沼誠久、加藤悠一、秀瀬涼太、蘆田弘樹、大林龍胆
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PUBLICLY-20H04862
[Patent] アミノ酸および/または有機酸を製造する方法2022
- Inventor(s)
  蓮沼誠久、加藤悠一、秀瀬涼太、蘆田弘樹、大林龍胆
- Industrial Property Rights Holder
  蓮沼誠久、加藤悠一、秀瀬涼太、蘆田弘樹、大林龍胆
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-110536
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K15142
[Patent] 環境負荷の低い物質生産方法2022
- Inventor(s)
  蓮沼誠久、蘆田弘樹、大林龍胆、秀瀬涼太、稲邊宏輔
- Industrial Property Rights Holder
  蓮沼誠久、蘆田弘樹、大林龍胆、秀瀬涼太、稲邊宏輔
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PUBLICLY-20H04862
[Patent] 芳香族系化合物を生産する方法2019
- Inventor(s)
  蓮沼誠久、大林龍胆、蘆田弘樹
- Industrial Property Rights Holder
  蓮沼誠久、大林龍胆、蘆田弘樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-101419
- Filing Date
  2019
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] バクテリアにおいて多倍数体は進化にとって有利なのか？2024
- Author(s)
  大林龍胆
- Organizer
  第71回日本生態学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] 細胞成長とゲノム複製間における協調関係の解明2024
- Author(s)
  安村健伸、大林龍胆
- Organizer
  第18回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] ゲノム多倍数体における 1 ゲノムあたりの転写、翻訳活性の定量2024
- Author(s)
  村木遥飛、奥本麗奈、大林龍胆
- Organizer
  第18回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] シアノバクテリアにおけるゲノム倍数性と転写、翻訳活性の相関2023
- Author(s)
  村木遥飛、奥本麗奈、大林龍胆
- Organizer
  第17回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H04862
[Presentation] シアノバクテリアにおけるゲノム倍数性と転写、翻訳活性の相関2023
- Author(s)
  村木遥飛、奥本麗奈、大林龍胆
- Organizer
  第17回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] ゲノム倍数体における遺伝様式の解明2022
- Author(s)
  大林龍胆、畠山哲央
- Organizer
  藍藻の分子生物学2022
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] ゲノム倍数性生物におけるゲノム継承機構の解明2022
- Author(s)
  大林龍胆、畠山哲央
- Organizer
  第16回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] なぜ、生物はゲノムを複数持つのか？2022
- Author(s)
  奥本麗奈、大林龍胆
- Organizer
  第一回総合微生物学研究会
- Data Source
  KAKENHI-PUBLICLY-20H04862
[Presentation] シアノバクテリアのDnaAに依存しないゲノム複製開始機構の解明2022
- Author(s)
  大石葉月、大林龍胆
- Organizer
  第一回総合微生物学研究会
- Data Source
  KAKENHI-PUBLICLY-20H04862
[Presentation] ゲノム倍数体における遺伝様式の解明2022
- Author(s)
  大林龍胆、畠山哲央
- Organizer
  藍藻の分子生物学2022
- Data Source
  KAKENHI-PUBLICLY-20H04862
[Presentation] なぜ、生物はゲノムを複数持つのか？2022
- Author(s)
  奥本麗奈、大林龍胆
- Organizer
  第一回総合微生物学研究会
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] シアノバクテリアのDnaAに依存しないゲノム複製開始機構の解明2022
- Author(s)
  大石葉月、大林龍胆
- Organizer
  第一回総合微生物学研究会
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] ゲノム倍数体生物における遺伝様式と進化可能性2021
- Author(s)
  大林龍胆、畠山哲央
- Organizer
  日本遺伝学会第93回大会
- Data Source
  KAKENHI-PROJECT-21K15142
[Presentation] シアノバクテリアでは染色体複製におけるDnaA非依存への進化は複数回独立に起きている2020
- Author(s)
  大林龍胆、廣岡俊亮、大沼亮、広瀬侑、兼崎友、古澤力、宮城島進也
- Organizer
  第14日本ゲノム微生物学会
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] Replication and inheritance mechanism of multi-copy genomes in bacteria and organelle2020
- Author(s)
  Ryudo Ohbayashi
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] Replication and inheritance mechanism of multi-copy genomes in bacteria and organelle.2020
- Author(s)
  Ryudo Ohbayashi
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04862
[Presentation] シアノバクテリアの染色体複製におけるDnaA依存性進化2019
- Author(s)
  大林龍胆、廣岡俊亮、大沼亮、広瀬侑、兼崎友、宮城島進也
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] 倍数ゲノムの複製、遺伝様式から紐解くシアノバクテリアの進化可能性2019
- Author(s)
  大林龍胆
- Organizer
  藍藻の分子生物学2019
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] 複数コピー染色体の複製、遺伝様式2019
- Author(s)
  大林龍胆、畠山哲央、宮城島進也
- Organizer
  第13回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] Impact of polyploidy on the evolutionary rate2019
- Author(s)
  Ryudo Ohbayashi, Tetsuhiro S Hatakeyama
- Organizer
  第56回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] 複数コピー染色体において複製システムが及ぼす進化可能性2019
- Author(s)
  大林龍胆
- Organizer
  第13回日本ゲノム微生物学会若手の会
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] 遺伝様式から考えるゲノム倍数性がもたらす進化可能性2018
- Author(s)
  大林龍胆
- Organizer
  生命科学系フロンティアミーティング2018
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] 細胞の成長に相関した複数コピー染色体の複製制御機構とその普遍性2018
- Author(s)
  大林龍胆、宮城島進也
- Organizer
  日本遺伝学会第90回大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] 細胞成長に伴うゲノムコピー数の増加とその制御機構2018
- Author(s)
  大林龍胆
- Organizer
  第12回日本ゲノム微生物学会
- Data Source
  KAKENHI-PROJECT-16H07418
[Presentation] ゲノム倍数性が及ぼす進化可能性～実験的検証の試み～2018
- Author(s)
  大林龍胆、畠山哲央
- Organizer
  日本進化学会第20回大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04827
[Presentation] バクテリアゲノムの構造、倍数性と複製機構から考える進化と意義2017
- Author(s)
  大林龍胆
- Organizer
  NGS現場の会
- Invited
- Data Source
  KAKENHI-PROJECT-16H07418
[Presentation] シアノバクテリアにおける複数コピーゲノムの複製制御機構2017
- Author(s)
  大林龍胆、中町愛、渡辺智、兼崎友、吉川博文、宮城島進也
- Organizer
  第11回日本ゲノム微生物学会年会
- Place of Presentation
  慶應義塾大学　湘南藤沢キャンパス
- Year and Date
  2017-03-02
- Data Source
  KAKENHI-PROJECT-16H07418
[Presentation] マルチコピーゲノムの複製制御機構からゲノムの存在意義を探る2017
- Author(s)
  大林龍胆
- Organizer
  藍藻の分子生物学2017
- Data Source
  KAKENHI-PROJECT-16H07418

1. KANESAKI Yu

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# of Collaborated Products: 2 results
2. OHBA Yusaku

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# of Collaborated Products: 1 results
3. YOSHIKAWA Kanako

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# of Collaborated Products: 1 results
4. MIYAGISHIMA Sin-ya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 藤原崇之

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# of Collaborated Products: 2 results
6. 渡辺智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohbayashi Ryudo 大林 龍胆

Research Projects

Research Products

Co-Researchers

細胞内共生前に獲得したDnaA非依存型ゲノム複製機構とその進化的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

倍数ゲノム複製機構がもたらす新規機能獲得と進化速度の両立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノム倍数性がもたらす進化可能性～揺らぎと安定性の両立～Principal Investigator

Principal Investigator

Project Period (FY)

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Analyses of regulation mechanism of DNA replication and its evolutionary significance in cyanobacteria and chloroplastPrincipal Investigator

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[Journal Article] Glycogen deficiency enhances carbon partitioning into glutamate for an alternative extracellular metabolic sink in cyanobacteria2024

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[Journal Article] Discovery of novel replication proteins for large plasmids in cyanobacteria and their potential applications in genetic engineering2024

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[Journal Article] ppGpp accumulation reduces the expression of the global nitrogen homeostasis-modulating NtcA regulon by affecting 2-oxoglutarate levels2023

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[Journal Article] Evolutionary Innovation by Polyploidy2022

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[Journal Article] 細胞増殖に伴うラン藻の複数コピーゲノムの維持機構2021

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[Journal Article] Specific binding of DnaA to the DnaA box motif in the cyanobacterium <i>Synechococcus elongatus</i> PCC 79422020

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[Journal Article] Relationship between Cell Cycle and Diel Transcriptomic Changes in Metabolism in a Unicellular Red Alga2020

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[Journal Article] Evolutionary Changes in DnaA-Dependent Chromosomal Replication in Cyanobacteria2020

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[Journal Article] Integration of a Galdieria plasma membrane sugar transporter enables heterotrophic growth of the obligate photoautotrophic red alga Cynanidioschyzon merolae2019

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[Journal Article] Coordination of Polyploid Chromosome Replication With Cell Size and Growth in a Cyanobacterium.2019

Ohbayashi Ryudo 大林龍胆