Sato Ryota 佐藤亮太

Researcher Number	90779703
Other IDs
Affiliation (Current)	2025: 千葉大学, 未来粘膜ワクチン研究開発シナジー拠点, 特任助教
Affiliation (based on the past Project Information) *help	2024: 東京大学, 医科学研究所, 助教 2020 – 2022: 東京大学, 医科学研究所, 助教 2019: 東京大学, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related
Keywords	Principal Investigator TLR / HSV / ウイルス / 自然免疫 / 核酸リガンド / 肝臓 / マクロファージ / RNase / Immunometabolism / 脂質代謝 / 代謝免疫学 / ウイルス学

DNAストレスによる自然免疫応答の多様性及び変容の解明Principal Investigator
- Principal Investigator
  
  佐藤亮太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokyo
Exploration of TLR3 ligands and the regulatory mechanism of response through nucleases in HSV infection.Principal Investigator
- Principal Investigator
  
  Sato Ryota
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokyo
Analysis of function of mTORC2 as fatty acid sensor in TLR3 responsePrincipal Investigator
- Principal Investigator
  
  Sato Ryota
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes.2023
- Author(s)
  Kuchitsu Y, Mukai K, Uematsu R, Takaada Y, Shinojima A, Shindo R, Shoji T, Hamano S, Ogawa E, Sato R, Miyake K, Kato A, Kawaguchi Y, Nishitani-Isa M, Izawa K, Nishikomori R, Yasumi T, Suzuki T, Dohmae N, Uemura T, Barber GN, Arai H, Waguri S, Taguchi T.
- Journal Title
  
  Nature Cell Biology
  
  Volume: 25 Issue: 3 Pages: 453-466
- DOI
  10.1038/s41556-023-01098-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07104, KAKENHI-PROJECT-21K19498, KAKENHI-PUBLICLY-22H05584, KAKENHI-PROJECT-20H03202, KAKENHI-PROJECT-20H03415, KAKENHI-PROJECT-21K15464, KAKENHI-PROJECT-20H03492, KAKENHI-PUBLICLY-21H00338, KAKENHI-PUBLICLY-22H04631, KAKENHI-PROJECT-22K07829, KAKENHI-PROJECT-22K19424, KAKENHI-PLANNED-22H05184, KAKENHI-PROJECT-21H04800
[Journal Article] Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment2022
- Author(s)
  Miyake Kensuke、Shibata Takuma、Fukui Ryutaro、Sato Ryota、Saitoh Shin-Ichiroh、Murakami Yusuke
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 941931-941937
- DOI
  10.3389/fimmu.2022.941931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03466, KAKENHI-PROJECT-21K15464
[Journal Article] Role of the orphan transporter SLC35E1 in the nuclear egress of herpes simplex virus 12022
- Author(s)
  Fumio Maeda, Akihisa Kato, Kosuke Takeshima, Misato Shibazaki, Ryota Sato, Takuma Shibata, Kensuke Miyake, Hiroko Kozuka-Hata, Masaaki Oyama, Eigo Shimizu, Seiya Imoto, Satoru Miyano, Shungo Adachi, Tohru Natsume, Koh Takeuchi, Yuhei Maruzuru, Naoto Koyanagi, Jun Arii, Yasushi Kawaguchi
- Journal Title
  
  Journal of Virology
  
  Volume: - Issue: 10 Pages: 10-10
- DOI
  10.1128/jvi.00306-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22524, KAKENHI-PROJECT-20K07511, KAKENHI-PROJECT-21K19370, KAKENHI-PROJECT-21K19498, KAKENHI-PROJECT-22K15468, KAKENHI-PLANNED-21H05280, KAKENHI-PLANNED-22H05184, KAKENHI-PUBLICLY-22H05584, KAKENHI-PROJECT-21H04800, KAKENHI-PROJECT-20H03496, KAKENHI-PROJECT-21K15464, KAKENHI-PROJECT-20H05692, KAKENHI-PROJECT-20H03492, KAKENHI-PUBLICLY-21H00338, KAKENHI-PUBLICLY-21H00417, KAKENHI-WRAPUP-22H04899, KAKENHI-PROJECT-20H03378
[Journal Article] Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment.2021
- Author(s)
  Miyake K, Saitoh S-I, Fukui R, Shibata T, Sato R, and Murakami Y.
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 835-840
- DOI
  10.1093/intimm/dxab037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04900, KAKENHI-PROJECT-21H04800, KAKENHI-PROJECT-21K15464, KAKENHI-PROJECT-20H03466
[Journal Article] Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes2021
- Author(s)
  Murakami Yusuke、Fukui Ryutaro、Tanaka Reika、Motoi Yuji、Kanno Atsuo、Sato Ryota、Yamaguchi Kiyoshi、Amano Hirofumi、Furukawa Yoichi、Suzuki Hitoshi、Suzuki Yusuke、Tamura Naoto、Yamashita Naomi、Miyake Kensuke
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 0-0
- DOI
  10.3389/fimmu.2021.777197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08892, KAKENHI-PROJECT-21K15464, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K07563
[Journal Article] Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages2021
- Author(s)
  Liu Kaiwen、Sato Ryota、Shibata Takuma、Hiranuma Ryosuke、Reuter Tatjana、Fukui Ryutaro、Zhang Yun、Ichinohe Takeshi、Ozawa Manabu、Yoshida Nobuaki、Latz Eicke、Miyake Kensuke
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 9 Pages: 479-490
- DOI
  10.1093/intimm/dxab033
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03162, KAKENHI-PROJECT-21H04800, KAKENHI-PROJECT-20H03491, KAKENHI-PROJECT-21K15464, KAKENHI-PROJECT-16H06276
[Journal Article] The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages2020
- Author(s)
  Sato R, Reuter T, Hiranuma R, Shibata T, Fukui R, Motoi Y, Murakami Y, Tsukamoto H, Yamazaki S, Liu K, Saitoh SI, Latz E, Miyake K.
- Journal Title
  
  Int Immunol
  
  Volume: 32 Issue: 12 Pages: 785-798
- DOI
  10.1093/intimm/dxaa055
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21612, KAKENHI-PUBLICLY-18H04856, KAKENHI-PUBLICLY-20H04900, KAKENHI-PUBLICLY-20H05025, KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-20H03466, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-18K06651, KAKENHI-PROJECT-18K07169, KAKENHI-PROJECT-19K16685, KAKENHI-PROJECT-19H03451, KAKENHI-PROJECT-19K22635
[Journal Article] Identification of a herpes simplex virus 1 gene encoding neurovirulence factor by chemical proteomics2020
- Author(s)
  Kato Akihisa、Adachi Shungo、Kawano Shuichi、Takeshima Kousuke、Watanabe Mizuki、Kitazume Shinobu、Sato Ryota、Kusano Hideo、Koyanagi Naoto、Maruzuru Yuhei、Arii Jun、Hatta Tomohisa、Natsume Tohru、Kawaguchi Yasushi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 4894-4894
- DOI
  10.1038/s41467-020-18718-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07511, KAKENHI-PROJECT-19K22524, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-17H04080, KAKENHI-PROJECT-17H05069, KAKENHI-PUBLICLY-20H04899, KAKENHI-PROJECT-18K15164, KAKENHI-PROJECT-19K21256, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06433, KAKENHI-PROJECT-20H05692, KAKENHI-PROJECT-20H03492, KAKENHI-PROJECT-19K16685, KAKENHI-PUBLICLY-21H00338, KAKENHI-ORGANIZER-15H05935, KAKENHI-WRAPUP-20H05615
[Journal Article] Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors2019
- Author(s)
  Miyake Kensuke、Saitoh Shin‐ichiroh、Sato Ryota、Shibata Takuma、Fukui Ryutaro、Murakami Yusuke
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 106 Issue: 4 Pages: 853-862
- DOI
  10.1002/jlb.mr0119-020r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16685, KAKENHI-PUBLICLY-18H04666, KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-19H03451, KAKENHI-PROJECT-19K22635
[Presentation] The role of RNase T2 in macrophage homeostasis.2022
- Author(s)
  Ryota Sato, Kaiwen Liu, Takuma Shibata, Ryutaro Fukui, Katsuaki Hoshino, Toshikazu Kondo, Yuko Ishida, Toru Miyazaki, Tsuneyasu Kaisho, Kensuke Miyake
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-21K15464
[Presentation] The role of RNase T2 in macrophage homeostasis.2021
- Author(s)
  Ryota Sato, Kaiwen Liu, Takuma Shibata, Ryutaro Fukui, Katsuaki Hoshino, Tsuneyasu Kaisho, Kensuke Miyake
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-21K15464
[Presentation] Combating herpesvirus encephalitis by potentiating a TLR3-mTOR axis2019
- Author(s)
  Ryota Sato, Akihisa Kato, Takahiko Chimura, Glen N Barber, Toshiya Manabe, Yasushi Kawaguchi, Kensuke Miyake
- Organizer
  Keystone Symposia Immunometabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16685
[Presentation] Combating herpesvirus encephalitis by potentiating a TLR3-mTOR axis2019
- Author(s)
  Ryota Sato, Akihisa Kato, Takahiko Chimura, Glen N Barber, Toshiya Manabe, Yasushi Kawaguchi, Kensuke Miyake
- Organizer
  AIFII2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16685
[Presentation] Combating herpesvirus encephalitis by potentiating a TLR3-mTOR axis2019
- Author(s)
  Ryota Sato, Akihisa Kato, Takahiko Chimura, Glen N Barber, Toshiya Manabe, Yasushi Kawaguchi, Kensuke Miyake
- Organizer
  IUIS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16685
[Presentation] Combating herpesvirus encephalitis by potentiating a TLR3-mTOR axis2019
- Author(s)
  Ryota Sato, Akihisa Kato, Takahiko Chimura, Glen N Barber, Toshiya Manabe, Yasushi Kawaguchi, Kensuke Miyake
- Organizer
  ICBL2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16685

1. UEMURA Takefumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. OZAWA Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 斉藤伸一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 川口寧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 天野浩文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 山崎聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 丸鶴雄平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sato Ryota 佐藤 亮太

Research Projects

Research Products

Co-Researchers

DNAストレスによる自然免疫応答の多様性及び変容の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of TLR3 ligands and the regulatory mechanism of response through nucleases in HSV infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of function of mTORC2 as fatty acid sensor in TLR3 responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the orphan transporter SLC35E1 in the nuclear egress of herpes simplex virus 12022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of a herpes simplex virus 1 gene encoding neurovirulence factor by chemical proteomics2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] The role of RNase T2 in macrophage homeostasis.2022

Author(s)

Organizer

Data Source

[Presentation] The role of RNase T2 in macrophage homeostasis.2021

Author(s)

Organizer

Data Source

[Presentation] Combating herpesvirus encephalitis by potentiating a TLR3-mTOR axis2019

Author(s)

Organizer

Data Source

[Presentation] Combating herpesvirus encephalitis by potentiating a TLR3-mTOR axis2019

Sato Ryota 佐藤亮太