HIRATA Tetsuya 平田哲也

Researcher Number	90780651
Other IDs
Affiliation (based on the past Project Information) *help	2023: 岐阜大学, 高等研究院, 特任助教 2022: 岐阜大学, 研究推進・社会連携機構, 特任助教 2020 – 2021: 岐阜大学, 高等研究院, 特任助教 2017 – 2018: 生理学研究所, 分子細胞生理研究領域, 特任助教 2016 – 2017: 大阪大学, 微生物病研究所, 特任研究員(常勤)
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related / Structural biochemistry Except Principal Investigator Basic Section 38040:Bioorganic chemistry-related / Neurophysiology / General neuroscience / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator 糖脂質 / GPIアンカー / ノックアウトマウス / 糖転移酵素 / プリオン / 糖鎖修飾 / 骨形成 / 脳機能 / PGAP4 / プリオン病 … More / 糖鎖 / ナノドメイン / 脱パルミトイル化 / 質量分析 / 神経細胞 / ノックインマウス / ABHD17 / PSD95 / シナプス / パルミトイル化 / 立体構造モデル / GPI … More Except Principal Investigator 蛋白質 / 生理学 / シナプス / 蛍光ラベル / PGAP4 / B3GALT4 / 糖転移酵素 / 蛍光プローブ / 糖鎖合成 / 糖脂質GPI / 脳・神経 / 脂質 / Zdk1-iLID / LOVTRAP / 酵素 / ABHD17 / LOV2 / 光科学 / タンパク質 / NMDA受容体 / 超解像顕微鏡 / 遺伝学 / 脳神経疾患 / 神経科学 / LGI1 / パルミトイル化 / 脱パルミトイル化酵素 / ナノドメイン / 脱パルミトイル化 / てんかん / PSD-95 / パルミトイル化脂質修飾 / グルタミン酸受容体 / AMPA受容体 Less

Mechanism for diversifying the branched structure of GPI elucidated by interdisciplinary research in glycochemistry and glycobiology
- Principal Investigator
  
  Tanaka Hide-Nori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Gifu University
GPIアンカー側鎖の生理機能と疾患との関連の解明Principal Investigator
- Principal Investigator
  
  平田哲也
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Gifu University
脱パルミトイル化によるシナプス局所領域の維持機構とその生理的意義の解明Principal Investigator
- Principal Investigator
  
  平田哲也
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  National Institute for Physiological Sciences
GPI側鎖の生合成機構及びその生理的意義の解明Principal Investigator
- Principal Investigator
  
  平田哲也
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
Optogenetic manipulation of protein palmitoylation for synapse organization
- Principal Investigator
  
  Masaki Fukata
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Institute for Physiological Sciences
Mechanisms for AMPA-type glutamate receptor anchoring at the synapse
- Principal Investigator
  
  FUKATA Yuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Institute for Physiological Sciences

All 2022 2021 2018 2016

All Journal Article Presentation

[Journal Article] Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology.2022
- Author(s)
  Tetsuya Hirata, Atsushi Kobayashi, Tamio Furuse, Ikuko Yamada, Masaru Tamura, Hiroyuki Tomita, Yuko Tokoro, Akinori Ninomiya, Yoshitaka Fujihara, Masahito Ikawa, Yusuke Maeda, Yoshiko Murakami, Yasuhiko Kizuka, and Taroh Kinoshita.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: - Issue: 3 Pages: 101720-101720
- DOI
  10.1016/j.jbc.2022.101720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15746, KAKENHI-PROJECT-19H03457
[Journal Article] Biology of Glycosylphosphatidylinositol (GPI)-anchor Side Chains and Free GPI2021
- Author(s)
  Tetsuya Hirata
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 33 Issue: 196 Pages: E129-E134
- DOI
  10.4052/tigg.2041.1E
- NAID
  130008120294
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2021-11-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15746
[Journal Article] Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals2021
- Author(s)
  Jing Yang, Tetsuya Hirata, Yi-Shi Liu, Xin-Yu Guo, Xiao-Dong Gao, Taroh Kinoshita, and Morihisa Fujita
- Journal Title
  
  FEBS Letters
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15746
[Journal Article] パルミトイル化修飾酵素を軸とした神経機能研究2018
- Author(s)
  平田哲也，深田優子，深田正紀
- Journal Title
  
  生化学
  
  Volume: 90
- NAID
  40021617357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14560
[Journal Article] パルミトイル化修飾酵素を軸とした神経機能研究2018
- Author(s)
  平田哲也，深田優子，深田正紀
- Journal Title
  
  生化学
  
  Volume: 90
- NAID
  40021617357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04279
[Journal Article] Palmitoylation/depalmitoylation enzymes in neuroscience research2018
- Author(s)
  平田哲也、深田優子、深田正紀
- Journal Title
  
  生化学
  
  Volume: 90 Issue: 2 Pages: 125-137
- DOI
  10.14952/SEIKAGAKU.2018.900125
- NAID
  40021617357
- ISSN
  0037-1017
- Year and Date
  2018-04-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14707
[Presentation] GPIアンカーのGalNAc側鎖の生理的、病理的な役割2021
- Author(s)
  平田哲也
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K15746
[Presentation] 立体構造モデルに基づいたGPI-GalNAc転移酵素PGAP4によるGPI側鎖合成機構2016
- Author(s)
  平田哲也、Sushil Kumar Mishra、中村昇太、元岡大祐、神澤範行、藤田盛久、村上良子、前田裕輔、山口芳樹、木下タロウ
- Organizer
  第35回日本糖質学会年会
- Place of Presentation
  高知県・高知市
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-16H06939
[Presentation] The mechanism for the addition of GPI side-chain by PGAP4, a GPI-GalNAc transferase, predicted from its 3D model2016
- Author(s)
  Tetsuya Hirata, Sushil Kumar Mishra, Shota Nakamura, Daisuke Motooka, Noriyuki Kanzawa, Morihisa Fujita, Yoshiko Murakami, Yusuke Maeda, Yoshiki Yamaguchi, Taroh Kinoshita
- Organizer
  8th ACGG Annual Conference
- Place of Presentation
  中国・無錫市
- Year and Date
  2016-10-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06939

1. FUKATA Yuko (40416186)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. YOKOI Norihiko (50710969)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. INAHASHI Hiroki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SUZUKI Yumi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Masaki Fukata (00335027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Tanaka Hide-Nori (20725064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 藤田盛久 (30532056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAHASHI Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SEKIYA Atsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MURAKAMI Tatsuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FURUKAWA Sachiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KANADOME Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WATANABE Mie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIRATA Tetsuya 平田 哲也

Research Projects

Research Products

Co-Researchers

Mechanism for diversifying the branched structure of GPI elucidated by interdisciplinary research in glycochemistry and glycobiology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

GPIアンカー側鎖の生理機能と疾患との関連の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脱パルミトイル化によるシナプス局所領域の維持機構とその生理的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

GPI側鎖の生合成機構及びその生理的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Optogenetic manipulation of protein palmitoylation for synapse organization

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms for AMPA-type glutamate receptor anchoring at the synapse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biology of Glycosylphosphatidylinositol (GPI)-anchor Side Chains and Free GPI2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals2021

Author(s)

Journal Title

Data Source

[Journal Article] パルミトイル化修飾酵素を軸とした神経機能研究2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] パルミトイル化修飾酵素を軸とした神経機能研究2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Palmitoylation/depalmitoylation enzymes in neuroscience research2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Presentation] GPIアンカーのGalNAc側鎖の生理的、病理的な役割2021

Author(s)

Organizer

HIRATA Tetsuya 平田哲也